Presence of t(14; 18) translocation in healthy individuals varies according to ethnic background in the Brazilian population
Levy, D; Bertoldi, ERM; Ruiz, JLM; Pereira, J; Bydlowski, SP.
Braz. j. med. biol. res
; 50(7): e6172, 2017. tab, graf
Artigo
em Inglês
| LILACS | ID: biblio-839317
Several groups have demonstrated that healthy individuals can present the t(14;18) translocation. In this report, the presence of the translocation was examined in healthy blood donors in Brazil, a country considered an ethnic melting pot. The translocation was detected by nested PCR in 227 peripheral blood samples from individuals with different ethnic backgrounds. The t(14;18) translocation was found in 45 of 85 White individuals (52.94%); in 57 of 72 Black individuals (79.17%); and in 68 of 70 individuals (97.14%) of Japanese-descent. In conclusion, the frequency of the t(14;18) translocation in the Brazilian population varies according to the ethnic background.
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BR1.1
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