Micobacteriose cutânea atípica felina autóctone no município do Rio de Janeiro-Brasil / Autochthonous Case of Feline Atypical Cutaneous Mycobacteriosis in the Municipality of Rio de Janeiro-Brazil

Background: Cutaneous mycobacterioses show a worldwide distribution and manifest as three forms: atypical mycobacteriosis, feline leprosy and cutaneous tuberculosis. Atypical cutaneous mycobacteriosis in cats is a rare disease commonly caused by fast-growing mycobacteria belonging group IV of the Runyon classification. This report describes for the first time an autochthonous case of atypical cutaneous mycobacteriosis in a cat from the municipality of Rio de Janeiro. Case: A castrated female mongrel cat presented multiple ulcerated, exudative and alopecic lesions in different regions of the body. After sedation of the animal with 1% acepromazine hydrochloride (0.1 mg/kg) and 10% ketamine hydrochloride (10 mg/kg), clinical examination was performed and an exudate was collected from the ulcerated skin lesion for cytopathological analysis and mycological culture. The slide containing the lesion impression was stained by a rapid panoptic method. For fungal culture, material was collected with a sterile swab, seeded onto Sabouraud dextrose agar containing chloramphenicol and mycobiotic agar, and incubated at 25ºC. After antisepsis and asepsis, local anesthesia was performed with 2% lidocaine hydrochloride without vasoconstrictor and a 4 mm punch biopsy was collected from the lesion, fixed in 10% buffered formalin and sent for histopathological analysis. No fungal structures were detected by cytopathological or mycological analysis. Histopathological examination revealed ulcerated skin and the presence of a marked and diffuse pyogranulomatous infiltrate in the superficial and deep dermis, which also involving the subcutaneous tissue and underlying muscle tissue. Grocott’s or PAS staining did not identify fungal structures. The Wade method was positive for acid-fast bacteria suggestive of Mycobacterium. Analysis of the hematological and biochemical profiles revealed no noteworthy alterations.(...)

Micobacteriose cutânea atípica felina autóctone no município do Rio de Janeiro-Brasil / Autochthonous Case of Feline Atypical Cutaneous Mycobacteriosis in the Municipality of Rio de Janeiro-Brazil

Background: Cutaneous mycobacterioses show a worldwide distribution and manifest as three forms: atypical mycobacteriosis, feline leprosy and cutaneous tuberculosis. Atypical cutaneous mycobacteriosis in cats is a rare disease commonly caused by fast-growing mycobacteria belonging group IV of the Runyon classification. This report describes for the first time an autochthonous case of atypical cutaneous mycobacteriosis in a cat from the municipality of Rio de Janeiro. Case: A castrated female mongrel cat presented multiple ulcerated, exudative and alopecic lesions in different regions of the body. After sedation of the animal with 1% acepromazine hydrochloride (0.1 mg/kg) and 10% ketamine hydrochloride (10 mg/kg), clinical examination was performed and an exudate was collected from the ulcerated skin lesion for cytopathological analysis and mycological culture. The slide containing the lesion impression was stained by a rapid panoptic method. For fungal culture, material was collected with a sterile swab, seeded onto Sabouraud dextrose agar containing chloramphenicol and mycobiotic agar, and incubated at 25ºC. After antisepsis and asepsis, local anesthesia was performed with 2% lidocaine hydrochloride without vasoconstrictor and a 4 mm punch biopsy was collected from the lesion, fixed in 10% buffered formalin and sent for histopathological analysis. No fungal structures were detected by cytopathological or mycological analysis. Histopathological examination revealed ulcerated skin and the presence of a marked and diffuse pyogranulomatous infiltrate in the superficial and deep dermis, which also involving the subcutaneous tissue and underlying muscle tissue. Grocotts or PAS staining did not identify fungal structures. The Wade method was positive for acid-fast bacteria suggestive of Mycobacterium. Analysis of the hematological and biochemical profiles revealed no noteworthy alterations.(...)(AU)

Síndrome lepra felina: aspectos dermatohistopatológicos / Dermatohistopathology in feline leprosy syndrome

As dermatopatias micobacterianas dos gatos vem apresentando interesse crescente devido à heterogeneidadeclínica, microbiológica e patológica. Entre as principais síndromes relacionadas estão a lepra felina, focodesta revisão, as micobacterioses cutâneas atípicas e a tuberculose cutânea felina. A lepra felina é caracterizada por granulomas cutâneos ou subcutâneos únicos ou múltiplos contendo bacilos álcool-ácido resistentes, acompanhadas geralmente por linfoadenopatia. É dividida histologicamente nas formas tuberculóide e lepromatóide,na dependência de fatores tais como a idade, apresentação clínica e histomorfologia. Os principais agentesenvolvidos nestas afecções incluem o M. lepraemurium, M. fortuitum, M.phlei, M. smegmatis, M. chelonae, M.thermoresistible e M. fortuitum-peregrinum. Entretanto, outros agentes não relacionados ao gênero Mycobacterium spp têm sido detectados por técnicas moleculares. A presente revisão descreve os principais aspectos histopatológicos e etiológicos, dos casos de lesões lepromatosas felinas. (AU)

Mycobacterial skin diseases in cats have been showing increasing interest due to different clinical, microbiologicaland pathological presentation. The main syndromes associated with this disease are feline leprosy, focus of this review, atypical mycobacteriosis and feline cutaneous tuberculosis. Feline leprosy ischaracterized by cutaneous or subcutaneous granulomas containing single or multiple acid-fast bacilli, usually accompanied by lymphadenopathy. It might be divided histologically in lepromatoid and tuberculoid forms, depending on factors such as age, clinical presentation and histomorphology. The main etiologicalagents involved in these disorders include M. lepraemurium, M. fortuitum, M.phlei, M. smegmatis, M. chelonae,and M. thermoresistible, and M. fortuitum-peregrinum. However, other Mycobacterium spp non-related agentshave been detected by molecular techniques. The present review describes the major histopathological and etiological aspects of feline cases of lepromatous lesions. (AU)

Síndrome lepra felina: aspectos dermatohistopatológicos / Dermatohistopathology in feline leprosy syndrome

As dermatopatias micobacterianas dos gatos vem apresentando interesse crescente devido à heterogeneidadeclínica, microbiológica e patológica. Entre as principais síndromes relacionadas estão a lepra felina, focodesta revisão, as micobacterioses cutâneas atípicas e a tuberculose cutânea felina. A lepra felina é caracterizada por granulomas cutâneos ou subcutâneos únicos ou múltiplos contendo bacilos álcool-ácido resistentes, acompanhadas geralmente por linfoadenopatia. É dividida histologicamente nas formas tuberculóide e lepromatóide,na dependência de fatores tais como a idade, apresentação clínica e histomorfologia. Os principais agentesenvolvidos nestas afecções incluem o M. lepraemurium, M. fortuitum, M.phlei, M. smegmatis, M. chelonae, M.thermoresistible e M. fortuitum-peregrinum. Entretanto, outros agentes não relacionados ao gênero Mycobacterium spp têm sido detectados por técnicas moleculares. A presente revisão descreve os principais aspectos histopatológicos e etiológicos, dos casos de lesões lepromatosas felinas.

Mycobacterial skin diseases in cats have been showing increasing interest due to different clinical, microbiologicaland pathological presentation. The main syndromes associated with this disease are feline leprosy, focus of this review, atypical mycobacteriosis and feline cutaneous tuberculosis. Feline leprosy ischaracterized by cutaneous or subcutaneous granulomas containing single or multiple acid-fast bacilli, usually accompanied by lymphadenopathy. It might be divided histologically in lepromatoid and tuberculoid forms, depending on factors such as age, clinical presentation and histomorphology. The main etiologicalagents involved in these disorders include M. lepraemurium, M. fortuitum, M.phlei, M. smegmatis, M. chelonae,and M. thermoresistible, and M. fortuitum-peregrinum. However, other Mycobacterium spp non-related agentshave been detected by molecular techniques. The present review describes the major histopathological and etiological aspects of feline cases of lepromatous lesions.

Micobacteriose cutânea atípica felina autóctone no município do Rio de Janeiro-Brasil

Background:  :  : Cutaneous mycobacterioses show a worldwide distribution and manifest as three forms: atypical mycobacteriosis, feline leprosy and cutaneous tuberculosis. Atypical cutaneous mycobacteriosis in cats is a rare disease commonly caused by fast-growing mycobacteria belonging group IV of the Runyon classification. This report describes for the first time an autochthonous case of atypical cutaneous mycobacteriosis in a cat from the municipality of Rio de Janeiro. Case: A castrated female mongrel cat presented multiple ulcerated, exudative and alopecic lesions in different regions of the body. After sedation of the animal with 1% acepromazine hydrochloride (0.1 mg/kg) and 10% ketamine hydrochloride (10 mg/kg), clinical examination was performed and an exudate was collected from the ulcerated skin lesion for cytopathological analysis and mycological culture. The slide containing the lesion impression was stained by a rapid panoptic method. For fungal culture, material was collected with a sterile swab, seeded onto Sabouraud dextrose agar containing chloramphenicol and mycobiotic agar, and incubated at 25ºC. After antisepsis and asepsis, local anesthesia was performed with 2% lidocaine hydrochloride without vasoconstrictor and a 4 mm punch biopsy was collected from the lesion, fixed in 10% buffered formalin and sent for histopathological analysis. No fungal structures we

Micobacteriose cutânea atípica felina autóctone no município do Rio de Janeiro-Brasil

Background:  :  : Cutaneous mycobacterioses show a worldwide distribution and manifest as three forms: atypical mycobacteriosis, feline leprosy and cutaneous tuberculosis. Atypical cutaneous mycobacteriosis in cats is a rare disease commonly caused by fast-growing mycobacteria belonging group IV of the Runyon classification. This report describes for the first time an autochthonous case of atypical cutaneous mycobacteriosis in a cat from the municipality of Rio de Janeiro. Case: A castrated female mongrel cat presented multiple ulcerated, exudative and alopecic lesions in different regions of the body. After sedation of the animal with 1% acepromazine hydrochloride (0.1 mg/kg) and 10% ketamine hydrochloride (10 mg/kg), clinical examination was performed and an exudate was collected from the ulcerated skin lesion for cytopathological analysis and mycological culture. The slide containing the lesion impression was stained by a rapid panoptic method. For fungal culture, material was collected with a sterile swab, seeded onto Sabouraud dextrose agar containing chloramphenicol and mycobiotic agar, and incubated at 25ºC. After antisepsis and asepsis, local anesthesia was performed with 2% lidocaine hydrochloride without vasoconstrictor and a 4 mm punch biopsy was collected from the lesion, fixed in 10% buffered formalin and sent for histopathological analysis. No fungal structures we