Correção de deformidade flexural da articulação metacarpofalangeana em uma bezerra / Correction of flexural deformity of the metacarpophalangeal joint in a calf

Background: The congenital flexural deformity is common in cattle, often affecting the metacarpophalangeal joint of thethoracic limbs. The deformity may be mild, moderate, or severe, and the therapy depends on the limb’s degree of flexionand the affected joint. In severe deformities, tenotomy of the flexor tendons and desmotomy of the suspensor ligament isrecommended. However, this surgical technique may not be sufficient to promote limb extension, and other interventionsmay be necessary. Thus, the purpose of this report is to describe a technique to correct severe flexural deformities of themetacarpophalangeal joint in calves.Case: A 3-month-old, female, Dutch-bred calf weighing 46 kg was referred for treatment of congenital flexural deformity.On attendance, the patient presented severe deformity in the right thoracic limb and mild in the left thoracic limb both at theheight of the metacarpophalangeal joints. During palpation it was possible to notice that the flexor tendons were contractedin both limbs. Radiographic exams were performed to rule out the presence of other diseases, confirming the diagnosis offlexural deformity. The patient was referred to surgery to correct the anatomical anomaly. The animal was submitted to general anesthesia and placed in right lateral decubitus. In the left thoracic limb, an incision was made in the medial region ofthe metacarpal bone, the tissues were divulsioned until the superficial digital and deep digital flexor tendons were exposed;these structures were sectioned with a scalpel, and the limb was extended, returning to the standard anatomical position. Inthe right thoracic limb, the same procedure was performed, but during the limb extension test, we observed that the limbremained flexed, we then followed with a second incision and section of the deep...

Clinical and arthroscopic presentation of horses with osteochondral fragmentation at metacarpophalangeal and metatarsophalangeal joints: a 10-year study (2010-2019) / Caracterização clínica e artroscópica de equinos com fragmentação osteocondral em articulações metacarpofalangeana e metatarsofalangeana: estudo de 10 anos (2010-2019)

This study aimed to characterize the clinical and arthroscopic presentations of horses with osteochondral fragmentation at the metacarpophalangeal and metatarsophalangeal joints at the Veterinary Hospital of the University of São Paulo in a 10-year period (2010-2019). The hind limbs were affected similarly to the plantar and dorsal fragments from the first phalanx, while the thoracic limbs had a more frequent occurrence on the dorsal aspect of the joint. The Brazilian Sport Horses were the most frequently observed breed. The degree of lameness was variable and might be related to fragment localization, animal age, and physical activity. There was a significant statistical difference between the joint effusion and degree of lameness; therefore, it can be considered that the joint effusion is related to degenerative joint processes and might be triggered by the presence of the osteochondral fragment. Surgical correction, especially when performed in young animals using an arthroscopic procedure is probably the best treatment option for most cases, possibly acting as a minimizer of the occurrence of secondary joint degeneration. Prospective studies of specific breeds with a larger number of animals can expand this clinical characterization and enable a better understanding of the animal's recovery after surgical or conservative management.

O objetivo deste estudo foi caracterizar a apresentação clínica e artroscópica de equinos com fragmentação osteocondral em articulação metacarpo/metatarsofalangeana atendidos no Hospital Veterinário da Universidade de São Paulo, no período de 10 anos (2010-2019). Os membros pélvicos são mais acometidos com fragmentos plantaromediais da primeira falange, enquanto os membros torácicos apresentam uma caracterização de ocorrência de fragmentação dorsal da primeira falange, sendo o Brasileiro de Hipismo a raça de maior ocorrência nesta casuística. O grau de claudicação foi variável e pode relacionar-se com a localização do fragmento, a idade e o nível de atividade atlética desenvolvida. Houve relação estatística significativa entre a presença de efusão articular e o grau de claudicação, por isso suscita-se sobre a efusão relacionar-se com processos degenerativos articulares que podem ser desencadeados pela presença do fragmento osteocondral. A correção cirúrgica por meio de procedimento artroscópico provavelmente consiste na melhor opção de tratamento para a maioria dos casos, principalmente quando realizada em animais jovens, possivelmente atuando como minimizador da ocorrência de degeneração articular secundária. Estudos prospectivos de raças específicas e com um número maior de animais podem ampliar essa caracterização clínica e possibilitar um entendimento sobre a evolução após a opção ou não pelo tratamento cirúrgico.

Deformidade flexural adquirida da articulação metacarpofalangeana esquerda em bezerra - relato de caso / Acquired flexural deformity of the left metacarpophalangeal joint of a female calf - case report

O presente trabalho relata o caso de uma bezerra com deformidade flexural adquirida da articulação metacarpofalangeana esquerda de origem idiopática. No exame físico o animal não conseguia se locomover normalmente e, durante o exame de extensão e flexão, foi constatada a rigidez da articulação metacarpofalangeana do lado esquerdo. O tratamento instituído foi a imobilização do membro acometido com tala de PVC e a administração de oxitetraciclina, associada a dexametasona. Decorridos oito dias do tratamento a tala foi retirada e a bezerra passou a apoiar o membro no chão, locomovendo-se normalmente.

The present paper is a case report of a heifer presenting an acquired flexural deformity of the left metacarpophalangeal joint of idiopathic origin. During the physical examination it was observed that the animal was unable to move normally and during the extension and flexion examination it was found rigidity of the left metacarpophalangeal joint. The treatment applied was the immobilization of the affected limb with PVC splint and administration of Oxytetracycline, associated with Dexamethasone. After eight days, the splint was removed and the heifer was moving normally supporting his limb on the ground.

Deformidade flexural adquirida da articulação metacarpofalangeana esquerda em bezerra - relato de caso / Acquired flexural deformity of the left metacarpophalangeal joint of a female calf - case report

O presente trabalho relata o caso de uma bezerra com deformidade flexural adquirida da articulação metacarpofalangeana esquerda de origem idiopática. No exame físico o animal não conseguia se locomover normalmente e, durante o exame de extensão e flexão, foi constatada a rigidez da articulação metacarpofalangeana do lado esquerdo. O tratamento instituído foi a imobilização do membro acometido com tala de PVC e a administração de oxitetraciclina, associada a dexametasona. Decorridos oito dias do tratamento a tala foi retirada e a bezerra passou a apoiar o membro no chão, locomovendo-se normalmente.(AU)

The present paper is a case report of a heifer presenting an acquired flexural deformity of the left metacarpophalangeal joint of idiopathic origin. During the physical examination it was observed that the animal was unable to move normally and during the extension and flexion examination it was found rigidity of the left metacarpophalangeal joint. The treatment applied was the immobilization of the affected limb with PVC splint and administration of Oxytetracycline, associated with Dexamethasone. After eight days, the splint was removed and the heifer was moving normally supporting his limb on the ground.(AU)

Manejo da deformidade flexural congênita em bezerro - aspectos cirúrgicos e patológicos / Management of a congenital flexural deformity in a calf - surgical and pathological aspects

Background: Flexural deformities are anatomical deviations, in varying degrees, of one or more joints, and may have a congenital or acquired origin. Congenital contracture of the deep digital flexor tendon (DDFT) affects newborn calves and results in hyperflexion of the metacarpal-phalangeal joint, which in severe cases means that the animal must support its own weight on its fetlock joints. The aim of this study is to report the rapid and successful result of applying bilateral total tenotomy technique on a newborn bovine that had been diagnosed with severe bilateral DDFT contracture in the thoracic limbs. Case: A 3-week-old male bovine with a history of difficulty in maintaining a quadrupedal position was attended at the Veterinary Hospital of the Federal University of Tocantins. The animal had severe bilateral locomotor alterations in the thoracic members to the point that he walked on his fetlock joints. The physical examination revealed clinical parameters within the normal range. However, the locomotor system examination showed severe flexor deformity in the bilateral metacarpal-phalangeal joints, and the limbs were being supported on the dorsal face of the fetlock joints, which presented ulcerations, and was suggestive of a shortening of the DDFT. Based on the patient’s history and clinical examination, as well as the severity of the tendon contractures, surgical treatment using the DDFT bilateral total tenotomy technique was decided upon. Postoperative treatment consisted of 2.5 mg/kg of enrofloxacin intramuscularly (IM), SID, for 5 days and 0.5 mg/kg meloxicam via IM, SID, for 3 days; as well as a dressing (cotton, medical bandage and a PVC mold) on the thoracic limbs to provide support and allow the animal to..

Manejo da deformidade flexural congênita em bezerro - aspectos cirúrgicos e patológicos / Management of a congenital flexural deformity in a calf - surgical and pathological aspects

Background: Flexural deformities are anatomical deviations, in varying degrees, of one or more joints, and may have a congenital or acquired origin. Congenital contracture of the deep digital flexor tendon (DDFT) affects newborn calves and results in hyperflexion of the metacarpal-phalangeal joint, which in severe cases means that the animal must support its own weight on its fetlock joints. The aim of this study is to report the rapid and successful result of applying bilateral total tenotomy technique on a newborn bovine that had been diagnosed with severe bilateral DDFT contracture in the thoracic limbs. Case: A 3-week-old male bovine with a history of difficulty in maintaining a quadrupedal position was attended at the Veterinary Hospital of the Federal University of Tocantins. The animal had severe bilateral locomotor alterations in the thoracic members to the point that he walked on his fetlock joints. The physical examination revealed clinical parameters within the normal range. However, the locomotor system examination showed severe flexor deformity in the bilateral metacarpal-phalangeal joints, and the limbs were being supported on the dorsal face of the fetlock joints, which presented ulcerations, and was suggestive of a shortening of the DDFT. Based on the patients history and clinical examination, as well as the severity of the tendon contractures, surgical treatment using the DDFT bilateral total tenotomy technique was decided upon. Postoperative treatment consisted of 2.5 mg/kg of enrofloxacin intramuscularly (IM), SID, for 5 days and 0.5 mg/kg meloxicam via IM, SID, for 3 days; as well as a dressing (cotton, medical bandage and a PVC mold) on the thoracic limbs to provide support and allow the animal to..(AU)

Deformidade flexural em potro / Flexural deformity in foal

As deformidades flexurais são caracterizadas pelo desvio da orientação normal do membro, detectadas pela permanente hiperflexão de uma ou mais regiões articulares. O termo deformidade flexural ou tendões contraídos tem sido utilizado tradicionalmente para representar várias deformidades flexoras nos membros. Todavia, o potencial para contração deste tecido é limitado. O defeito primário não está necessariamente no tendão. As deformidades flexurais congênitas devem ser tratadas imediatamente após o seu diagnóstico, com a severidade da deformidade ditando o quão agressivo será o tratamento. Quanto mais novo for o potro, melhor a resposta ao tratamento, devido ao fato de que os tecidos se tornam menos responsivos ao tratamento com o passar do tempo. O presente trabalho teve como objetivo relatar um caso de deformidade flexural em um potro submetido a tratamento conservativo. Foi atendido pelo HGV-Hospital Geral Veterinário, em Aquiraz, um potro, macho, não castrado, com cinco dias de idade, pesando aproximadamente 50kg, o proprietário relatou que após o nascimento o potro estava com os cascos projetados dorsalmente e com dificuldade de locomoção. Ao exame clínico, constatou-se que o potro apresentava hiperflexão bilateral dos membros torácicos, ocasionando deformidade flexural metacarpofalangeana e interfalangeana. Após o diagnóstico foi instituído tratamento à base de oxitetraciclina e tiocochilcosideo e o uso de talas de PVC. O tratamento conservativo com uso da oxitetraciclina e do tiocolchicosídeo no caso de deformidade flexural no potro do presente relato foi eficiente, revertendo o quadro sem trazer sequelas ao potro.

Flexural deformities are characterized by deviation from the normal orientation of the limb, detected by the permanent hyperflexion of one or more joint regions. The term flexural deformity or contracted tendons has traditionally been used to represent various flexor deformities in the limbs. However, the potential for contraction of this tissue is limited. The primary defect is not necessarily in the tendon. Congenital flexural deformities should be treated immediately after diagnosis, with the severity of the deformity dictating how aggressive the treatment will be. The younger the foal, the better the response to treatment, due to the fact that the tissues become less responsive to treatment over time. The present study aimed to report a case of flexural deformity in a foal submitted to conservative treatment. Was attended by HGV-Hospital Geral Veterinário, in Aquiraz, a foal, male, uncastrated, with five days of age, weighing approximately 50kg, the owner reported that after birth the foal had its hooves projected dorsally and with difficulty in locomotion. On clinical examination, it was found that the foal had bilateral hyperflexion of the thoracic limbs, causing metacarpophalangeal and interphalangeal flexural deformity. After the diagnosis, treatment based on oxytetracycline and thiocochylcoside was instituted and the use of PVC splints. Conservative treatment with the use of oxytetracycline and thiocolchicoside in the case of flexural deformity in the foal of the present report was efficient, reversing the condition without causing sequels to the foal.

Deformidade flexural em potro / Flexural deformity in foal

As deformidades flexurais são caracterizadas pelo desvio da orientação normal do membro, detectadas pela permanente hiperflexão de uma ou mais regiões articulares. O termo deformidade flexural ou tendões contraídos tem sido utilizado tradicionalmente para representar várias deformidades flexoras nos membros. Todavia, o potencial para contração deste tecido é limitado. O defeito primário não está necessariamente no tendão. As deformidades flexurais congênitas devem ser tratadas imediatamente após o seu diagnóstico, com a severidade da deformidade ditando o quão agressivo será o tratamento. Quanto mais novo for o potro, melhor a resposta ao tratamento, devido ao fato de que os tecidos se tornam menos responsivos ao tratamento com o passar do tempo. O presente trabalho teve como objetivo relatar um caso de deformidade flexural em um potro submetido a tratamento conservativo. Foi atendido pelo HGV-Hospital Geral Veterinário, em Aquiraz, um potro, macho, não castrado, com cinco dias de idade, pesando aproximadamente 50kg, o proprietário relatou que após o nascimento o potro estava com os cascos projetados dorsalmente e com dificuldade de locomoção. Ao exame clínico, constatou-se que o potro apresentava hiperflexão bilateral dos membros torácicos, ocasionando deformidade flexural metacarpofalangeana e interfalangeana. Após o diagnóstico foi instituído tratamento à base de oxitetraciclina e tiocochilcosideo e o uso de talas de PVC. O tratamento conservativo com uso da oxitetraciclina e do tiocolchicosídeo no caso de deformidade flexural no potro do presente relato foi eficiente, revertendo o quadro sem trazer sequelas ao potro.(AU)

Flexural deformities are characterized by deviation from the normal orientation of the limb, detected by the permanent hyperflexion of one or more joint regions. The term flexural deformity or contracted tendons has traditionally been used to represent various flexor deformities in the limbs. However, the potential for contraction of this tissue is limited. The primary defect is not necessarily in the tendon. Congenital flexural deformities should be treated immediately after diagnosis, with the severity of the deformity dictating how aggressive the treatment will be. The younger the foal, the better the response to treatment, due to the fact that the tissues become less responsive to treatment over time. The present study aimed to report a case of flexural deformity in a foal submitted to conservative treatment. Was attended by HGV-Hospital Geral Veterinário, in Aquiraz, a foal, male, uncastrated, with five days of age, weighing approximately 50kg, the owner reported that after birth the foal had its hooves projected dorsally and with difficulty in locomotion. On clinical examination, it was found that the foal had bilateral hyperflexion of the thoracic limbs, causing metacarpophalangeal and interphalangeal flexural deformity. After the diagnosis, treatment based on oxytetracycline and thiocochylcoside was instituted and the use of PVC splints. Conservative treatment with the use of oxytetracycline and thiocolchicoside in the case of flexural deformity in the foal of the present report was efficient, reversing the condition without causing sequels to the foal.(AU)

Intra-articular concentration of gentamicin administered by intravenous regional limb perfusion in healthy horses / Concentração intra-articular de gentamicina administrada por perfusão regional intravenosa em membros de equinos sadios

Intravenous regional limb perfusion (IRLP) is an efficient method to treat horses with synovial infections. However, information on the dose, volume, and intervals of administration is lacking. The aim of this study was to evaluate the intra-articular concentration of gentamicin administered by IRLP in horses over 24 h post-administration and evaluate the influence of the total perfused volume. Twenty horses were assigned to two treatment groups. Gentamicin 60 group (G60, n=10) and Gentamicin 250 group (G250, n=10) received IRLP of 6.6 mg/kg of gentamicin diluted in Ringers lactate for a total volume of 60 ml (G60) and 250 ml (G250), respectively. Synovial fluid harvests were performed in the metacarpophalangeal joint before (0) and 4, 8, 12, 16, 20, and 24 hours after IRLP. Agar diffusion was the assay for measuring gentamicin concentrations. Four hours after IRLP, the intra-articular concentration of gentamicin was 47.58±49.21 g/ml in G60 and 10.92±6.11 g/ml in G250. During the 24 h of harvest, the intra-articular concentration of gentamicin remained above the minimum inhibitory concentration for horses (MIC; 2 g/ml) in both experimental groups. In G60, the concentration of gentamicin in synovial fluid reached the maximal concentration and remained 8 to 10-fold higher than the MIC (Cmax: 16 to 20 g/ml) during 12 h after IRLP. These findings support that IRLP with 6.6 mg/kg of gentamicin diluted to a volume of 60 ml promotes intra-articular concentrations higher than 250 ml, remaining above the MIC for 24 h and at the maximum concentration for 12 h.(AU)

A perfusão regional intravenosa (PRI) em membros de equinos é um método comprovadamente eficiente para o tratamento de infecções sinoviais, porém ainda existem lacunas quanto à dose, volume e intervalos de administração a serem utilizados. Neste estudo, objetivou-se avaliar a concentração intra-articular da gentamicina administrada por PRI em equinos, ao longo de 24 horas pós-administração, bem como avaliar a influência do volume total perfundido. Vinte equinos foram distribuídos em dois grupos experimentais, Grupo Gentamicina 60 (G60) e Grupo Gentamicina 250 (G250), representados por 10 equinos em cada grupo que receberam, por PRI, 6,6 mg/kg de gentamicina diluída em Ringer lactato para um total de 60 ml (G60) ou 250 ml (G250). As colheitas de líquido sinovial foram realizadas, na articulação metacarpo-falangeana, antes do início do experimento e após 4, 8, 12, 16, 20, e 24 horas. Difusão em ágar foi o método para doseamento das concentrações de gentamicina. Quatro horas após a PRI, a concentração intra-articular da gentamicina era de 47,58±49,21 µg/ml no G60 e 10,92±6,11 µg/ml no G250. Durante as 24 horas de colheita, a concentração intra-articular de gentamicina permaneceu acima da concentração inibitória mínima (CIM) (2 g/ml) em ambos os grupos experimentais. No G60, as concentrações de gentamicina no líquido sinovial atingiram a concentração máxima e mantiveram-se 8 a 10 vezes mais elevadas que a CIM (Cmáx: 16 a 20 g/ml) durante 12 horas após a PRI. Conclui-se que a PRI em membros, com 6,6 mg/kg de gentamicina diluída para o volume de 60 ml, promove concentrações intra-articulares mais elevadas que o volume de 250 ml, permanecendo acima da CIM durante 24 horas e em concentração máxima durante 12 horas.(AU)

Sites of anesthetic block of the lateral and medial palmar metacarpal nerves in equines of indeterminate breed

Background: Local anesthesia blockage at equines claudication diagnosis besides favoring the beginning of the therapyand relieving patients pain, it allows the identification of the specific affected region and its origin, however, if it isdone incorrectly (by improper volume of anesthetics application and/or mistakenly nerve identification due to the lack ofanatomic referential) it may cause inflammation, infection or even tissue necrosis. The aim was describing anatomicallylateral and medial palmar metacarpal nerves in equines to improve diagnostic anesthetic block techniques on four metacarpophalangeal articulation joints of the specie.Materials, Methods & Results: A number of 20 thoracic limbs from 10 equines of indeterminate breed were used to befixated in 10% phormaldehyde and with a marked arterial system by water solution of red dyed latex. The structures wereidentified by dissection, and their denomination bases on Nomina Anatomica Veterinaria (N.A.V.) by the InternationalCommittee on Veterinary Gross Anatomical Nomenclature. The study had been approved by the Board of Ethics in AnimalUse of the University Center of Patos de Minas (UNIPAM), protocol n° 18/17. The lateral and medial palmar metacarpalnerves have been observed in all of the specimens originated from the deep branch of lateral palmar nerve, immediatelydistal to the intercarpal articulation. After its origin, the first nerve stretched ipsilaterally from the common trunk, whilstthe second nerve positioned counter-lateral manner after superficially crossing the interosseus muscle. Both penetrated atthe level of the mid third of the referred muscle and the metacarpal bone III and, assumed respectively a parallel medialposition to the metacarpal bone IV and lateral to the metacarpal II, being intimately associated to the palmar face of themetacarpal bone III. Distally, those nerves emerged from a palmar position to a lateral and medial to...(AU)

Sites of anesthetic block of the lateral and medial palmar metacarpal nerves in equines of indeterminate breed

Background: Local anesthesia blockage at equines claudication diagnosis besides favoring the beginning of the therapyand relieving patient’s pain, it allows the identification of the specific affected region and its origin, however, if it isdone incorrectly (by improper volume of anesthetics application and/or mistakenly nerve identification due to the lack ofanatomic referential) it may cause inflammation, infection or even tissue necrosis. The aim was describing anatomicallylateral and medial palmar metacarpal nerves in equines to improve diagnostic anesthetic block techniques on four metacarpophalangeal articulation joints of the specie.Materials, Methods & Results: A number of 20 thoracic limbs from 10 equines of indeterminate breed were used to befixated in 10% phormaldehyde and with a marked arterial system by water solution of red dyed latex. The structures wereidentified by dissection, and their denomination bases on Nomina Anatomica Veterinaria (N.A.V.) by the InternationalCommittee on Veterinary Gross Anatomical Nomenclature. The study had been approved by the Board of Ethics in AnimalUse of the University Center of Patos de Minas (UNIPAM), protocol n° 18/17. The lateral and medial palmar metacarpalnerves have been observed in all of the specimens originated from the deep branch of lateral palmar nerve, immediatelydistal to the intercarpal articulation. After its origin, the first nerve stretched ipsilaterally from the common trunk, whilstthe second nerve positioned counter-lateral manner after superficially crossing the interosseus muscle. Both penetrated atthe level of the mid third of the referred muscle and the metacarpal bone III and, assumed respectively a parallel medialposition to the metacarpal bone IV and lateral to the metacarpal II, being intimately associated to the palmar face of themetacarpal bone III. Distally, those nerves emerged from a palmar position to a lateral and medial to...

Artrodese metatarsofalângica por meio da técnica do cesto de aço modificada em potro / Metatarsophalangeal arthrodesis through the modified steel basket technique in foal

Background: The metacarpophalangeal and metatarsophalangeal joints are very demanded during high intensity exercises,and may be affected by osteoarthritis, fractures, luxations and rupture of the suspensory apparatus. Thus, arthrodesis maybe indicated to restore joint stability and accelerate the ankylosis process. The most commonly used surgical techniqueshave been associated with postoperative complications, including infection and failure of the implants, so it is importantto develop procedures that are less invasive procedures and promoting stable fixation. Therefore, the aim of this work isto report the use of the modified steel basket technique for metatarsophalangeal arthrodesis in a foal with hyperextensionof the joint due to rupture of the digital flexor muscles.Case: A 2-day-old male foal was admitted to clinical care, presenting multiple cutaneous wounds caused by dogs bites,located in the tarsus and thigh of the hindlimb. The animal presented in standing position and had no difficulty of movement,being initially treated through daily cleaning of the cutaneous wounds and systemic antibiotic therapy. Hyperextension ofthe metatarsophalangeal joint was evidenced after 20 days, being approached through tenotomy and tendon shortening,followed by tenorrhaphy and immobilization for 30 days. Due to the failure of the treatment, it was opted for metatarsophalangeal arthrodesis by modified steel basket technique. The procedure involved the implantation of a steel basket of25.0 mm in diameter x 25.0 mm long in a 24.0 mm hole created on the dorsal surface between the third metacarpal andthe proximal phalanx. The basket was filled with bone extracted from drilling and fixed with two cortical screws at anangle of 25° toward proximoplantar and distoplantar direction. Immobilization of the limb was performed postoperativelywith synthetic plaster cast for 45 days and, due to the persistence of lameness...

Artrodese metatarsofalângica por meio da técnica do cesto de aço modificada em potro / Metatarsophalangeal arthrodesis through the modified steel basket technique in foal

Background: The metacarpophalangeal and metatarsophalangeal joints are very demanded during high intensity exercises,and may be affected by osteoarthritis, fractures, luxations and rupture of the suspensory apparatus. Thus, arthrodesis maybe indicated to restore joint stability and accelerate the ankylosis process. The most commonly used surgical techniqueshave been associated with postoperative complications, including infection and failure of the implants, so it is importantto develop procedures that are less invasive procedures and promoting stable fixation. Therefore, the aim of this work isto report the use of the modified steel basket technique for metatarsophalangeal arthrodesis in a foal with hyperextensionof the joint due to rupture of the digital flexor muscles.Case: A 2-day-old male foal was admitted to clinical care, presenting multiple cutaneous wounds caused by dogs bites,located in the tarsus and thigh of the hindlimb. The animal presented in standing position and had no difficulty of movement,being initially treated through daily cleaning of the cutaneous wounds and systemic antibiotic therapy. Hyperextension ofthe metatarsophalangeal joint was evidenced after 20 days, being approached through tenotomy and tendon shortening,followed by tenorrhaphy and immobilization for 30 days. Due to the failure of the treatment, it was opted for metatarsophalangeal arthrodesis by modified steel basket technique. The procedure involved the implantation of a steel basket of25.0 mm in diameter x 25.0 mm long in a 24.0 mm hole created on the dorsal surface between the third metacarpal andthe proximal phalanx. The basket was filled with bone extracted from drilling and fixed with two cortical screws at anangle of 25° toward proximoplantar and distoplantar direction. Immobilization of the limb was performed postoperativelywith synthetic plaster cast for 45 days and, due to the persistence of lameness...(AU)

Comparison of the effects of triamcinolone acetonide or platelet-rich plasma on expression of extracellular matrix-related genes in equine healthy chondrocytes in vitro / Comparação dos efeitos do acetonido de triancinolona ou plasma rico em plaquetas na expressão de genes relacionados à matriz extracelular de condrócitos in vitro de equinos adultos

In healthy cartilage, chondrocytes maintain an expression of collagens and proteoglycans and are sensitive to growth factors and cytokines that either enhance or reduce type II collagen synthesis. In osteoarthritis, pro-inflammatory cytokines, such as IL-6, induce overexpression of metalloproteinases (MMP) and decreasing synthesis of aggrecan. Use of chondroprotectors agents, such as Platelet-Rich Plasma (PRP) and triamcinolone (TA) are alternatives to reduce the progression of joint damage. In this study, we used chondrocytes extracted from metacarpophalangeal joints of healthy horses as the experimental model. Cells were treated in vitro with PRP or TA. No differences were observed between these treatments in comparison to the control group when the expressions of MMP9, MMP13, IL-6 and ACAN genes were evaluated (P<0.05). With these results, we can suggest that the treatments were not deleterious to equine cultured chondrocyte, once they did not stimulate MMPs and IL-6 synthesis or caused changes in ACAN.(AU)

Na cartilagem saudável, os condrócitos mantêm a expressão de colágenos e proteoglicanos, sendo sensíveis a fatores de crescimento e citocinas que aumentam ou reduzem a síntese de colágeno tipo II. Na osteoartrite, citocinas pró-inflamatórias, como a IL-6, estimulam a expressão de metaloproteinases (MMP) e reduzem a síntese de agrecano. O uso de condroprotetores, como o Plasma Rico em Plaquetas (PRP) e triancinolona (TA) é uma alternativa para se reduzir a progressão do dano articular. Neste estudo foram usados condrócitos extraídos das articulações metacarpofalangeanas de equinos saudáveis. As células foram tratadas in vitro com TA ou PRP. Não foram observadas diferenças entre os tratamentos comparando-se com o grupo controle quanto à expressão genética de MMP-9, MMP-13, IL-6 e ACAN (p<0,05). Assim, pode-se sugerir que os tratamentos não foram deletérios ao cultivo de condrócitos, uma vez que não estimularam a síntese de MMP e IL-6 e nem causaram alterações no ACAN.(AU)

Histochemistry of equine damaged tendons, ligaments and articular cartilage

Background: The injury repair process in tendons and ligaments includes different phases such as inflammation, neovascularization, fibroblast proliferation and fibrosis. Collagen type and tissue characteristics of tendon and ligament repair are described such as type collagen differentiation and properties of the scars tissue. The degeneration of articular cartilage when, characterized by loss of the articular layers associated of the decreased of proteoglycans. The aim of this study is to describe by histochemistry techniques the characteristics of tissue scar, collagen type in the repair process of tendons and ligaments, as well as articular cartilage degeneration.Materials, Methods & Results: Tissue samples of equine tendons, ligaments and articular cartilage of the metacarpophalangeal joint region were evaluated by ultrasonography, macroscopically and prepared for routine histopathology (H&E staining). The inclusion criterion of the samples in this study was based on the presence of lesions characterized in H&E stain as fibroplasia, neovascularization, collagenolysis, chondroid metaplasia in tendons and ligaments and fibrillation and cartilaginous eburnation lesions in the articular cartilage samples. The Masson’s trichrome, Picrosirius red and Alcian blue staining techniques were also performed in addition to H&E. Pathologic findings in the tendons and ligaments included fibroplasia, collagenolysis, chondroid metaplasia and lymphohistioplasmacytic inflammation. Tendons and ligaments scars were composed of type III collagen but there was also some type I collagen. Fiber alignment of tendons and ligaments in the reorganization tissue was not flawless and the fiber appearance was characterized by a lack of the fiber crimp and parallelism. The fibroplasia was characterized by endotendinous tickening areas associated with the presence of loose connective tissue.[...]

Histochemistry of equine damaged tendons, ligaments and articular cartilage

Background: The injury repair process in tendons and ligaments includes different phases such as inflammation, neovascularization, fibroblast proliferation and fibrosis. Collagen type and tissue characteristics of tendon and ligament repair are described such as type collagen differentiation and properties of the scars tissue. The degeneration of articular cartilage when, characterized by loss of the articular layers associated of the decreased of proteoglycans. The aim of this study is to describe by histochemistry techniques the characteristics of tissue scar, collagen type in the repair process of tendons and ligaments, as well as articular cartilage degeneration.Materials, Methods & Results: Tissue samples of equine tendons, ligaments and articular cartilage of the metacarpophalangeal joint region were evaluated by ultrasonography, macroscopically and prepared for routine histopathology (H&E staining). The inclusion criterion of the samples in this study was based on the presence of lesions characterized in H&E stain as fibroplasia, neovascularization, collagenolysis, chondroid metaplasia in tendons and ligaments and fibrillation and cartilaginous eburnation lesions in the articular cartilage samples. The Massons trichrome, Picrosirius red and Alcian blue staining techniques were also performed in addition to H&E. Pathologic findings in the tendons and ligaments included fibroplasia, collagenolysis, chondroid metaplasia and lymphohistioplasmacytic inflammation. Tendons and ligaments scars were composed of type III collagen but there was also some type I collagen. Fiber alignment of tendons and ligaments in the reorganization tissue was not flawless and the fiber appearance was characterized by a lack of the fiber crimp and parallelism. The fibroplasia was characterized by endotendinous tickening areas associated with the presence of loose connective tissue.[...](AU)

Aspectos ultrassonográficos, anatômicos e histológicos normais da articulação metacarpofalangeana equina / Normal ultrasonographic, anatomical and histological aspects of the equine metacarpophalangeal joint

O objetivo deste estudo foi descrever e caracterizar as estruturas que compõem a articulação metacarpofalangena equina por meio de análise ultrassonográfica, anatômica e histológica. Membros torácicos equinos (=70), obtidos em instalações frigoríficas, foram submetidos a exame ultrassonográfico post mortem. Destes, 30 membros apresentaram imagens ultrassonográficas consideradas sem alterações. Posteriormente foi realizada a dissecação dos mesmos e o estudo anátomo-histológico. Critérios como tamanho, forma, arquitetura e ecogenicidade foram observados a fim de caracterizar as imagens ultrassonográficas, anatômicas e histológicas normais das estruturas ligamentares, tendíneas, capsulares e cartilaginosas da articulação metacarpofalangeana equina.(AU)

The purpose of this study was to describe and characterize the equine metacarpophalangeal joint structures through ultrasonographic, anatomical and histological analysis. Seventy forelimb specimens were obtained from a slaughterhouse and submitted to ultrasonographic evaluation. Thirty specimens without ultrasonographic detectable lesions were selected for dissection and subsequent anatomical and histological evaluation. Criteria such as size, shape, architecture and echogenicity were observed in order to characterize normal ligaments, tendons, joint capsule and articular cartilage of the metacarpophalangeal joint.(AU)

Aspectos ultrassonográficos, anatômicos e histológicos normais da articulação metacarpofalangeana equina / Normal ultrasonographic, anatomical and histological aspects of the equine metacarpophalangeal joint

O objetivo deste estudo foi descrever e caracterizar as estruturas que compõem a articulação metacarpofalangena equina por meio de análise ultrassonográfica, anatômica e histológica. Membros torácicos equinos (=70), obtidos em instalações frigoríficas, foram submetidos a exame ultrassonográfico post mortem. Destes, 30 membros apresentaram imagens ultrassonográficas consideradas sem alterações. Posteriormente foi realizada a dissecação dos mesmos e o estudo anátomo-histológico. Critérios como tamanho, forma, arquitetura e ecogenicidade foram observados a fim de caracterizar as imagens ultrassonográficas, anatômicas e histológicas normais das estruturas ligamentares, tendíneas, capsulares e cartilaginosas da articulação metacarpofalangeana equina.(AU)

The purpose of this study was to describe and characterize the equine metacarpophalangeal joint structures through ultrasonographic, anatomical and histological analysis. Seventy forelimb specimens were obtained from a slaughterhouse and submitted to ultrasonographic evaluation. Thirty specimens without ultrasonographic detectable lesions were selected for dissection and subsequent anatomical and histological evaluation. Criteria such as size, shape, architecture and echogenicity were observed in order to characterize normal ligaments, tendons, joint capsule and articular cartilage of the metacarpophalangeal joint.(AU)

Importancia del gestión racional en examen radiográfico de la articulación metacarpo/metatarsofalángica (menudillo) en caballos - revisión / Importance of rational handling in radiographic examination of metacarpo/metatarsophalangeal joint (fetlock) in horses - review / Importância do manejo racional no exame radiográfico da articulação metacarpo/metatarsofalângica (boleto) em equinos - revisão de literatura

Actualmente los caballos han sido incluidos en diversas actividades como el ocio, el deporte y la terapia. Entre los diversos sitios posibles de lesiones musculoesqueléticas en los caballos, las lesiones en la articulación metacarpofalángica son consideradas como una de las principales causas de claudicación. La radiografía es uno de los métodos de diagnóstico de mayor accesibilidad y contribuye al diagnóstico de las lesiones del aparato locomotor en la especie equina. Muchas de las tareas asociadas a la gestión de los caballos durante el procedimiento radiográfico, particularmente en las partes distales de las extremidades, pueden aumentar las reacciones de miedo, que conduce a la falta de cooperación del animal con el procedimiento y, en consecuencia, la generación de situaciones adversas para el animal y profesional involucrados. Esta revisión bibliográfica tiene como objetivo destacar la importancia de la gestión racional asociado con el examen radiográfico del metacarpo / metatarso-falángica (menudillo), destacando las principales dificultades para llevar a cabo lo examen radiográfico y los métodos facilitadores para el éxito de las proyecciones radiográficas esa región.(AU)

Currently the equines are being included in the most varied activities, such as leisure, sport and therapy. Among the various sites of musculoskeletal lesions in horses, the metacarpophalangeal joint injuries are considered as a major cause of lameness. Radiographic examination is one of the diagnostic methods of greater accessibility and contributes to the diagnosis of locomotor injuries in the equine species. Many of the tasks associated with the handling of equine during the radiographic procedure, particularly on the distal parts of the limbs, can increase fear reactions, leading to non-cooperation of the animal to the procedure and, consequently, generating adverse situations to the animal and professionals involved. This literature review aims to highlight the importance of rational management associated with radiographic examination of the metacarpo/metatarsophalangeal (fetlock), highlighting the main difficulties for the realization of the radiographic exam and the facilitators methods to success on radiographic projections of this region.(AU)

Atualmente os equinos têm sido incluídos nas mais variadas atividades, como lazer, esporte e terapia. Entre os vários possíveis sítios de lesões musculoesqueléticas em cavalos, as injúrias na articulação metacarpofalângica são consideradas como uma das principais causas de claudicação. A radiografia é uma das metodologias diagnósticas de maior acessibilidade e que contribui para o diagnóstico das lesões locomotoras na espécie equina. Muitas das tarefas associadas ao manejo dos equinos durante o procedimento radiográfico, particularmente nas regiões distais dos membros, podem aumentar as reações de medo, levando a não cooperação do animal para a realização do procedimento, gerando, consequentemente, situações adversas para o animal e profissionais envolvidos. Esta revisão de literatura tem como objetivo destacar a importância do manejo racional associado ao exame radiográfico da articulação metacarpo/metatarsofalângica (boleto), ressaltando as principais dificuldades enfrentadas para a realização do exame radiográfico e os métodos facilitadores para o sucesso das projeções radiográficas dessa região.(AU)

Importancia del gestión racional en examen radiográfico de la articulación metacarpo/metatarsofalángica (menudillo) en caballos - revisión / Importance of rational handling in radiographic examination of metacarpo/metatarsophalangeal joint (fetlock) in horses - review / Importância do manejo racional no exame radiográfico da articulação metacarpo/metatarsofalângica (boleto) em equinos - revisão de literatura

Actualmente los caballos han sido incluidos en diversas actividades como el ocio, el deporte y la terapia. Entre los diversos sitios posibles de lesiones musculoesqueléticas en los caballos, las lesiones en la articulación metacarpofalángica son consideradas como una de las principales causas de claudicación. La radiografía es uno de los métodos de diagnóstico de mayor accesibilidad y contribuye al diagnóstico de las lesiones del aparato locomotor en la especie equina. Muchas de las tareas asociadas a la gestión de los caballos durante el procedimiento radiográfico, particularmente en las partes distales de las extremidades, pueden aumentar las reacciones de miedo, que conduce a la falta de cooperación del animal con el procedimiento y, en consecuencia, la generación de situaciones adversas para el animal y profesional involucrados. Esta revisión bibliográfica tiene como objetivo destacar la importancia de la gestión racional asociado con el examen radiográfico del metacarpo / metatarso-falángica (menudillo), destacando las principales dificultades para llevar a cabo lo examen radiográfico y los métodos facilitadores para el éxito de las proyecciones radiográficas esa región.

Currently the equines are being included in the most varied activities, such as leisure, sport and therapy. Among the various sites of musculoskeletal lesions in horses, the metacarpophalangeal joint injuries are considered as a major cause of lameness. Radiographic examination is one of the diagnostic methods of greater accessibility and contributes to the diagnosis of locomotor injuries in the equine species. Many of the tasks associated with the handling of equine during the radiographic procedure, particularly on the distal parts of the limbs, can increase fear reactions, leading to non-cooperation of the animal to the procedure and, consequently, generating adverse situations to the animal and professionals involved. This literature review aims to highlight the importance of rational management associated with radiographic examination of the metacarpo/metatarsophalangeal (fetlock), highlighting the main difficulties for the realization of the radiographic exam and the facilitators methods to success on radiographic projections of this region.

Atualmente os equinos têm sido incluídos nas mais variadas atividades, como lazer, esporte e terapia. Entre os vários possíveis sítios de lesões musculoesqueléticas em cavalos, as injúrias na articulação metacarpofalângica são consideradas como uma das principais causas de claudicação. A radiografia é uma das metodologias diagnósticas de maior acessibilidade e que contribui para o diagnóstico das lesões locomotoras na espécie equina. Muitas das tarefas associadas ao manejo dos equinos durante o procedimento radiográfico, particularmente nas regiões distais dos membros, podem aumentar as reações de medo, levando a não cooperação do animal para a realização do procedimento, gerando, consequentemente, situações adversas para o animal e profissionais envolvidos. Esta revisão de literatura tem como objetivo destacar a importância do manejo racional associado ao exame radiográfico da articulação metacarpo/metatarsofalângica (boleto), ressaltando as principais dificuldades enfrentadas para a realização do exame radiográfico e os métodos facilitadores para o sucesso das projeções radiográficas dessa região.