Diferentes apresentações de duplicidade cervical identificadas em peças do aparelho reprodutor feminino de bovinos – Relato de 5 casos / Different presentations of cervical duplicity identified in pieces of the female bovine reproductive tract – Report of 5 cases

A utilização de biotecnologias reprodutivas exige um sistema reprodutor funcional e com boa conformação anatômica. O aparelho reprodutor feminino de bovinos é constituído por vulva, clitóris, vestíbulo, vagina, útero, tuba uterina e ovários. A cérvix é uma etrrutura similar a um esfíncter que atua como barreira física e química contra a penetração de agentes patogênicos e corpos estranhos nos cornos uterinos. O útero pode ser acometido por diversas afecções, dentre elas a duplicidade cervical, malformação hereditária e congênita causada pela falha na fusão dos ductos de Müller ou paramesonéfricos. Objetivou-se relatar a ocorrência de duplicidade cervical em peças do aparelho reprodutorde vacas destinadas ao abate na cidade de Bagé, RS. Foram identificadas cinco diferentes apresentações de cérvix dupla, através de inspeção visual e dissecação anatômica. Conclui-se que a duplicidade cervical pode se apresentar de diferentes maneiras, e embora o diagnóstico seja de fácil obtenção, grande parte dos relatos existentes foram realizados em peças do sistema reprodutor de fêmeas abatidas, não permitindo a estimativa da ocorrênciain vivo. Ressalta-se a importância da realização de exame ginecológico e ultrassonografia para o diagnóstico prévio à estação reprodutiva, permitindo o descarte de fêmeas acometidas. Palavras-chave: cérvix, útero, ductos de Müller. AbstractThe use of reproductive biotechnologies requires a functional reproductive system with good anatomical conformation. The female bovine reproductive tract consists of the vulva, clitoris, vestibule, vagina, uterus and ovaries. The cervix is a structure similar to a sphincter that acts as a physical and chemical barrier against the penetration of pathogenic agents and foreign bodies into the uterine horns. The uterus can be affected by several pathologies, among them cervical duplicity, a hereditary and congenital malformation caused by fusion failures of the Müller or paramesonephric ducts. The objective of this study was to report the occurrence of cervical duplicity in parts of the reproductive tract of cows slaughtered in the city of Bagé, RS. Five different presentations of double cervix were identified through visual inspection and anatomic dissection. It is concluded that cervical duplicity can be presented indifferent ways, and although the diagnosis is easy to obtain, most of the existing reports were performed on reproductive systems of slaughtered females, not allowing the estimation of in vivo occurrence. It is important to perform the gynecological examination and ultrasonography for the diagnosis prior to the reproductive season, discarding affected females. Keywords: cervix, uterus, Müller’s ducts. Introdução O aumento da demanda por proteína animal ao redor do mundo e a pressão exercida por outras culturas, como avicultura e suinocultura, fazem com que os índices de eficiência no processo produtivo da bovinocultura sejam aprimorados. Para isso, a pecuária se valeu de inúmeras biotecnologias, dentre elas as reprodutivas, que exigem cada vez mais o sistema reprodutor funcional e de boa conformação anatômica (Grunert e Gregory, 1984).

The use of reproductive biotechnologies requires a functional reproductive system with good anatomical conformation. The female bovine reproductive tract consists of the vulva, clitoris, vestibule, vagina, uterus and ovaries. The cervix is a structure similar to a sphincter that acts as a physical and chemical barrier against the penetration of pathogenic agents and foreign bodies into the uterine horns. The uterus can be affected by several pathologies, among them cervical duplicity, a hereditary and congenital malformation caused by fusion failures of the Müller or paramesonephric ducts. The objective of this study was to report the occurrence of cervical duplicity in parts of the reproductive tract of cows slaughtered in the city of Bagé, RS. Five different presentations of double cervix were identified through visual inspection and anatomic dissection. It is concluded that cervical duplicity can be presented indifferent ways, and although the diagnosis is easy to obtain, most of the existing reports were performed on reproductive systems of slaughtered females, not allowing the estimation of in vivo occurrence. It is important to perform the gynecological examination and ultrasonography for the diagnosis prior to the reproductive season, discarding affected females.

Müller’s duct persistence syndrome associated with cryptorchidism, Sertoli cell tumor and pyometra in a Miniature Schnauzer

Background: Sexual development disturbances (SDD) are divided in SDD with XX genotype (SDD XX) and SDD withXY genotype (SDD XY). Among SDD XY, the Müller’s duct persistence syndrome (MDPS) is characterized by XYkaryotype individuals with male external genitals; however, with internal female reproductive organs such as uterine horns,uterus, and cranial vagina portion. The MDPS cases and their related complications are considered very rare in veterinarymedicine. The aim of the present case report is to describe the clinical and pathological aspects of a MDPS case associatedwith cryptorchidism, Sertoli cell tumor, and pyometra in a Miniature Schnauzer dog.Case: A 7-year-old male Miniature Schnauzer weighting 7 kg was brought to veterinary consultation due to owner’s complain of frequent vomiting, apathy, abdominal algia and progressive scrotal enlargement in the last two months. Physicalexam reveals hyperthermia (39.7°C), discrete dehydration, enlarged popliteal lymph nodes as well as scrotum enlargementwith only one palpable testicle. A blood sample collected for complete blood count showed regenerative anemia, thrombocytopenia, and neutrophilia with left shift in the leukogram. Abdominal ultrasound examination indicated the presenceof a tubular structure filled by anechoic content extending from the scrotum to caudal abdomen. Moreover, a 6.39 x 8.54cm heterogeneous mass in the medial mesogastric region became evident. The patient was hospitalized and submittedto exploratory laparotomy after 24 h due to rectal temperature increase (41°C), worsened abdominal pain, and intenseapathy. There was free purulent liquid in abdominal cavity and two uterine horns were documented. The left uterine hornpasses through inguinal ring and both horns were filled by purulent material...

Diferentes apresentações de duplicidade cervical identificadas em peças do aparelho reprodutor feminino de bovinos Relato de 5 casos / Different presentations of cervical duplicity identified in pieces of the female bovine reproductive tract Report of 5 cases

A utilização de biotecnologias reprodutivas exige um sistema reprodutor funcional e com boa conformação anatômica. O aparelho reprodutor feminino de bovinos é constituído por vulva, clitóris, vestíbulo, vagina, útero, tuba uterina e ovários. A cérvix é uma etrrutura similar a um esfíncter que atua como barreira física e química contra a penetração de agentes patogênicos e corpos estranhos nos cornos uterinos. O útero pode ser acometido por diversas afecções, dentre elas a duplicidade cervical, malformação hereditária e congênita causada pela falha na fusão dos ductos de Müller ou paramesonéfricos. Objetivou-se relatar a ocorrência de duplicidade cervical em peças do aparelho reprodutorde vacas destinadas ao abate na cidade de Bagé, RS. Foram identificadas cinco diferentes apresentações de cérvix dupla, através de inspeção visual e dissecação anatômica. Conclui-se que a duplicidade cervical pode se apresentar de diferentes maneiras, e embora o diagnóstico seja de fácil obtenção, grande parte dos relatos existentes foram realizados em peças do sistema reprodutor de fêmeas abatidas, não permitindo a estimativa da ocorrênciain vivo. Ressalta-se a importância da realização de exame ginecológico e ultrassonografia para o diagnóstico prévio à estação reprodutiva, permitindo o descarte de fêmeas acometidas. Palavras-chave: cérvix, útero, ductos de Müller. AbstractThe use of reproductive biotechnologies requires a functional reproductive system with good anatomical conformation. The female bovine reproductive tract consists of the vulva, clitoris, vestibule, vagina, uterus and ovaries. The cervix is a structure similar to a sphincter that acts as a physical and chemical barrier against the penetration of pathogenic agents and foreign bodies into the uterine horns. The uterus can be affected by several pathologies, among them cervical duplicity, a hereditary and congenital malformation caused by fusion failures of the Müller or paramesonephric ducts. The objective of this study was to report the occurrence of cervical duplicity in parts of the reproductive tract of cows slaughtered in the city of Bagé, RS. Five different presentations of double cervix were identified through visual inspection and anatomic dissection. It is concluded that cervical duplicity can be presented indifferent ways, and although the diagnosis is easy to obtain, most of the existing reports were performed on reproductive systems of slaughtered females, not allowing the estimation of in vivo occurrence. It is important to perform the gynecological examination and ultrasonography for the diagnosis prior to the reproductive season, discarding affected females. Keywords: cervix, uterus, Müllers ducts. Introdução O aumento da demanda por proteína animal ao redor do mundo e a pressão exercida por outras culturas, como avicultura e suinocultura, fazem com que os índices de eficiência no processo produtivo da bovinocultura sejam aprimorados. Para isso, a pecuária se valeu de inúmeras biotecnologias, dentre elas as reprodutivas, que exigem cada vez mais o sistema reprodutor funcional e de boa conformação anatômica (Grunert e Gregory, 1984).(AU)

The use of reproductive biotechnologies requires a functional reproductive system with good anatomical conformation. The female bovine reproductive tract consists of the vulva, clitoris, vestibule, vagina, uterus and ovaries. The cervix is a structure similar to a sphincter that acts as a physical and chemical barrier against the penetration of pathogenic agents and foreign bodies into the uterine horns. The uterus can be affected by several pathologies, among them cervical duplicity, a hereditary and congenital malformation caused by fusion failures of the Müller or paramesonephric ducts. The objective of this study was to report the occurrence of cervical duplicity in parts of the reproductive tract of cows slaughtered in the city of Bagé, RS. Five different presentations of double cervix were identified through visual inspection and anatomic dissection. It is concluded that cervical duplicity can be presented indifferent ways, and although the diagnosis is easy to obtain, most of the existing reports were performed on reproductive systems of slaughtered females, not allowing the estimation of in vivo occurrence. It is important to perform the gynecological examination and ultrasonography for the diagnosis prior to the reproductive season, discarding affected females.(AU)

Müllers duct persistence syndrome associated with cryptorchidism, Sertoli cell tumor and pyometra in a Miniature Schnauzer

Background: Sexual development disturbances (SDD) are divided in SDD with XX genotype (SDD XX) and SDD withXY genotype (SDD XY). Among SDD XY, the Müllers duct persistence syndrome (MDPS) is characterized by XYkaryotype individuals with male external genitals; however, with internal female reproductive organs such as uterine horns,uterus, and cranial vagina portion. The MDPS cases and their related complications are considered very rare in veterinarymedicine. The aim of the present case report is to describe the clinical and pathological aspects of a MDPS case associatedwith cryptorchidism, Sertoli cell tumor, and pyometra in a Miniature Schnauzer dog.Case: A 7-year-old male Miniature Schnauzer weighting 7 kg was brought to veterinary consultation due to owners complain of frequent vomiting, apathy, abdominal algia and progressive scrotal enlargement in the last two months. Physicalexam reveals hyperthermia (39.7°C), discrete dehydration, enlarged popliteal lymph nodes as well as scrotum enlargementwith only one palpable testicle. A blood sample collected for complete blood count showed regenerative anemia, thrombocytopenia, and neutrophilia with left shift in the leukogram. Abdominal ultrasound examination indicated the presenceof a tubular structure filled by anechoic content extending from the scrotum to caudal abdomen. Moreover, a 6.39 x 8.54cm heterogeneous mass in the medial mesogastric region became evident. The patient was hospitalized and submittedto exploratory laparotomy after 24 h due to rectal temperature increase (41°C), worsened abdominal pain, and intenseapathy. There was free purulent liquid in abdominal cavity and two uterine horns were documented. The left uterine hornpasses through inguinal ring and both horns were filled by purulent material...(AU)

Aplasia uterina total em cadela com atrofia segmentar de vagina / Total uterine aplasia in bitch with segmental atrophy of vagina

Background: Congenital uterine malformations are rarely identified in domestic and human animals and are related to problems during the embryonic formation of the paramesonephric ducts. Cases of agenesis and segmental aplasia or unicorn uterus have been described in bitches, but there are no reports of total uterine aplasia in this specie. The report of a case of total uterine aplasia and segmental atrophy of the cranial vagina, accidentally diagnosed is reported herein.Case: An adult female bitch without defined breed in bad general condition was attended in the emergency service in a Veterinary Hospital. During anamnesis the information was restricted because it was an errant animal rescued for the consultation, but accompanied for at least 12 months in the environment in which it lived. Data related to the estrous cycle were unknown, but no gestation was observed in the last year. Investigations detected anemia and intense thrombocytopenia, azotemia and increased alanine aminotransferase. Two days later, with no progression, images suggestive of hemometra/ mucometra were observed during abdominal ultrasonography, and the patient underwent emergency ovariohysterectomy despite the general poor condition. Before the procedure the uterus was not routinely identified, but a fibromuscular, nontubular and thin structure occupied the region corresponding to the horns and uterine body, thickening in the cervix region. Death four days after surgery and sent to necropsy. During necropsy it was observed that the vulva and the vestibule of the vagina did not present macroscopic alterations, however there was a marked digitiform narrowing of the cranial region of the vagina, which ended in blind bottom. The mucosa in this narrowing was smooth, without folds. The microscopic structure of the ovaries, uterine tubes and caudal vagina were preserved.[...]

Aplasia uterina total em cadela com atrofia segmentar de vagina / Total uterine aplasia in bitch with segmental atrophy of vagina

Background: Congenital uterine malformations are rarely identified in domestic and human animals and are related to problems during the embryonic formation of the paramesonephric ducts. Cases of agenesis and segmental aplasia or unicorn uterus have been described in bitches, but there are no reports of total uterine aplasia in this specie. The report of a case of total uterine aplasia and segmental atrophy of the cranial vagina, accidentally diagnosed is reported herein.Case: An adult female bitch without defined breed in bad general condition was attended in the emergency service in a Veterinary Hospital. During anamnesis the information was restricted because it was an errant animal rescued for the consultation, but accompanied for at least 12 months in the environment in which it lived. Data related to the estrous cycle were unknown, but no gestation was observed in the last year. Investigations detected anemia and intense thrombocytopenia, azotemia and increased alanine aminotransferase. Two days later, with no progression, images suggestive of hemometra/ mucometra were observed during abdominal ultrasonography, and the patient underwent emergency ovariohysterectomy despite the general poor condition. Before the procedure the uterus was not routinely identified, but a fibromuscular, nontubular and thin structure occupied the region corresponding to the horns and uterine body, thickening in the cervix region. Death four days after surgery and sent to necropsy. During necropsy it was observed that the vulva and the vestibule of the vagina did not present macroscopic alterations, however there was a marked digitiform narrowing of the cranial region of the vagina, which ended in blind bottom. The mucosa in this narrowing was smooth, without folds. The microscopic structure of the ovaries, uterine tubes and caudal vagina were preserved.[...](AU)

Piometra associada a criptorquidismo em cão pseudo-hermafrodita masculino com síndrome da persistência dos ductos de Müller / Pyometra associated to cryptorchidism in a male pseudohermaphrodite dog with persistent Müllerian duct syndrome

O sexo genético é estabelecido no momento da fertilização, e os sexos gonadal e fenotípico durante o período de desenvolvimento embrionário. Quando há alguma alteração nesse desenvolvimento, os animais podem apresentar hermafroditismo. Cães pseudo-hermafroditas masculino podem apresentar a síndrome da persistência dos ductos de Müller, causada pela presença de um gene autossômico recessivo. Esses indivíduos possuem cariótipo 78 XY, genitália externa masculina, porém apresentam internamente uma porção cranial da vagina, corpo e corno uterinos, tubas uterinas e cérvix. O presente trabalho relata os achados clínicos, ultrassonográficos, histopatológicos e citogenético de um cão da raça Schnauzer pseudo-hermafrodita masculino com a síndrome da persistência dos ductos de Müller associada a piometra e criptorquidismo.(AU)

Genetic sex is established at the time of fertilization, and gonadal and phenotypic sex during the period of embryonic development. When there is a change in this development, the animals may present hermaphroditism. Male pseudo-hermaphrodite dogs may present the Müllerian persistence duct syndrome, caused by the presence of an autosomal recessive gene. These individuals have a 78 XY karyotype, male external genitalia, but internally present a cranial portion of the vagina, body and horn of the uterus, uterine tubes and cervix. The present study reports the clinical, ultrasonographic, histopathological and cytogenetic findings of a Schnauzer pseudohermaphrodite male dog with Müllerian persistence duct syndrome associated with pyometra and cryptorchidism.(AU)

Piometra associada a criptorquidismo em cão pseudo-hermafrodita masculino com síndrome da persistência dos ductos de Müller / Pyometra associated to cryptorchidism in a male pseudohermaphrodite dog with persistent Müllerian duct syndrome

O sexo genético é estabelecido no momento da fertilização, e os sexos gonadal e fenotípico durante o período de desenvolvimento embrionário. Quando há alguma alteração nesse desenvolvimento, os animais podem apresentar hermafroditismo. Cães pseudo-hermafroditas masculino podem apresentar a síndrome da persistência dos ductos de Müller, causada pela presença de um gene autossômico recessivo. Esses indivíduos possuem cariótipo 78 XY, genitália externa masculina, porém apresentam internamente uma porção cranial da vagina, corpo e corno uterinos, tubas uterinas e cérvix. O presente trabalho relata os achados clínicos, ultrassonográficos, histopatológicos e citogenético de um cão da raça Schnauzer pseudo-hermafrodita masculino com a síndrome da persistência dos ductos de Müller associada a piometra e criptorquidismo.

Genetic sex is established at the time of fertilization, and gonadal and phenotypic sex during the period of embryonic development. When there is a change in this development, the animals may present hermaphroditism. Male pseudo-hermaphrodite dogs may present the Müllerian persistence duct syndrome, caused by the presence of an autosomal recessive gene. These individuals have a 78 XY karyotype, male external genitalia, but internally present a cranial portion of the vagina, body and horn of the uterus, uterine tubes and cervix. The present study reports the clinical, ultrasonographic, histopathological and cytogenetic findings of a Schnauzer pseudohermaphrodite male dog with Müllerian persistence duct syndrome associated with pyometra and cryptorchidism.

Seminoma and sertolioma in a male pseudohermaphrodite dog with unilateral cryptorchidism: short communication / Seminoma e sertolioma em um cão pseudo-hermafrodita masculino e criptorquida unilateral: comunicação científica

A male miniature Schnauzer with cryptorchidism and a mass growth in the right inguinal canal was admitted to the clinical center of a veterinary hospital. During surgical resection of the mass, tubular formations were found, connecting the mass to the left testicle. Histopathology revealed that the tubular formations were uterine tubes and the mass was a seminoma associated with a sertolioma of the right testicle. Further analysis also showed atrophy of the left testicle. Cytogenetic evaluation revealed normal chromosomes of male gender, 78, XY, which led to the conclusion that this was a male pseudohermaphrodite.(AU)

Foi atendido na rotina clínica de um hospital veterinário, um cão, macho, da raça Schnauzer, criptorquida com massa em canal inguinal direito. Durante o procedimento cirúrgico para a retirada da massa, foi encontrada uma formação tubular a qual fazia a ligação entre essa massa e o testículo esquerdo. A análise histopatológica concluiu que a formação tubular tratava-se de tubas uterinas, a massa era o testículo direito com seminoma e sertolioma e o testículo esquerdo apresentava atrofia. A avaliação citogenética revelou cromossomos normais, do sexo masculino, 78, XY concluindo que se tratava de um pseudo-hermafrodita masculino.(AU)

Remaining uterine mesonephric duct cyst in female dog (Canis familiaris) first case report in Brazil / Cisto de ducto mesonéfrico uterino remanescente em cadela (Canis familiaris) - primeiro relato de caso no Brasil / Quiste remaneciente del ducto mesonéfrico uterino en perra (Canis familiaris) primero relato del caso en Brasil

The aim of work was to describe a remaining uterine mesonephric duct cyst in female Pinscher dog, with 8 years old. The main complaint of the owner was no heat at least 18 months. Clinical examination revealed presence of cysts in all teats, confirmed by cytopathologic exam. Haemogram, serum biochemical exams, urinalysis, radiographs of the thorax and abdominal ultrasound were performed and no changes were observed. During the ovaryhysterectomy was observed endometrial hyperplasia and the histopathologic diagnosis was remaining uterine mesonephric duct cyst associated with discrete endometrial hyperplasia. Was concluded that adequate histopathologycal identification of the uterine mesonephric duct cyst is crucial so do not mistake with neoplasia.(AU)

O objetivo do trabalho foi descrever um caso de cisto de ducto mesonéfrico remanescente uterino em cadela da raça Pinscher, 8 anos de idade. A principal queixa do proprietário foi ausência de cio com duração de 18 meses. No exame físico evidenciou-se presença de cistos em todos os tetos, confirmado pelo exame citopatológico. Foi realizado hemograma, exames de bioquímica sérica, urinálise, exame radiográfico do tórax e ultrassom abdominal, e não foram observadas alterações. Durante o procedimento de ovário-histerectomia, foi observada hiperplasia endometrial e o diagnóstico histopatológico foi de cisto de ducto mesonéfrico remanescente uterino associado à hiperplasia endometrial discreta. Concluiu-se que a identificação histopatológica adequada do cisto de ducto mesonéfrico uterino é crucial para que o mesmo não seja confundido com neoplasia.(AU)

El objetivo del trábalo fue describir un caso de quiste remaneciente del ducto mesonéfrico uterino en perra da raza Pinscher, 8 años de edad. La principal queja del propietario fue ausencia del cio con duración de 18 meses. El examen físico reveló una presencia de quistes en los techos, confirmado por examen citopatológico. Se realizaron hemograma, pruebas bioquímicas sérica, análisis de orina, radiografías de tórax y ecografía abdominal, y no se observaron cambios. Durante ovario histerectomía se observó hiperplasia endometrial y el diagnóstico histopatológico se fue quiste remaneciente del ducto mesonéfrico uterina asociado a la hiperplasia endometrial discreta. Se concluyó que la identificación histopatológico adecuada del ducto mesonéfrico uterina es crucial para que no se confunda con neoplasia.(AU)

Remaining uterine mesonephric duct cyst in female dog (Canis familiaris) – first case report in Brazil / Cisto de ducto mesonéfrico uterino remanescente em cadela (Canis familiaris) - primeiro relato de caso no Brasil / Quiste remaneciente del ducto mesonéfrico uterino en perra (Canis familiaris) – primero relato del caso en Brasil

The aim of work was to describe a remaining uterine mesonephric duct cyst in female Pinscher dog, with 8 years old. The main complaint of the owner was no heat at least 18 months. Clinical examination revealed presence of cysts in all teats, confirmed by cytopathologic exam. Haemogram, serum biochemical exams, urinalysis, radiographs of the thorax and abdominal ultrasound were performed and no changes were observed. During the ovaryhysterectomy was observed endometrial hyperplasia and the histopathologic diagnosis was remaining uterine mesonephric duct cyst associated with discrete endometrial hyperplasia. Was concluded that adequate histopathologycal identification of the uterine mesonephric duct cyst is crucial so do not mistake with neoplasia.

O objetivo do trabalho foi descrever um caso de cisto de ducto mesonéfrico remanescente uterino em cadela da raça Pinscher, 8 anos de idade. A principal queixa do proprietário foi ausência de cio com duração de 18 meses. No exame físico evidenciou-se presença de cistos em todos os tetos, confirmado pelo exame citopatológico. Foi realizado hemograma, exames de bioquímica sérica, urinálise, exame radiográfico do tórax e ultrassom abdominal, e não foram observadas alterações. Durante o procedimento de ovário-histerectomia, foi observada hiperplasia endometrial e o diagnóstico histopatológico foi de cisto de ducto mesonéfrico remanescente uterino associado à hiperplasia endometrial discreta. Concluiu-se que a identificação histopatológica adequada do cisto de ducto mesonéfrico uterino é crucial para que o mesmo não seja confundido com neoplasia.

El objetivo del trábalo fue describir un caso de quiste remaneciente del ducto mesonéfrico uterino en perra da raza Pinscher, 8 años de edad. La principal queja del propietario fue ausencia del cio con duración de 18 meses. El examen físico reveló una presencia de quistes en los techos, confirmado por examen citopatológico. Se realizaron hemograma, pruebas bioquímicas sérica, análisis de orina, radiografías de tórax y ecografía abdominal, y no se observaron cambios. Durante ovario histerectomía se observó hiperplasia endometrial y el diagnóstico histopatológico se fue quiste remaneciente del ducto mesonéfrico uterina asociado a la hiperplasia endometrial discreta. Se concluyó que la identificación histopatológico adecuada del ducto mesonéfrico uterina es crucial para que no se confunda con neoplasia.

Occurrence of freemartinism in Santa Ines sheep / Ocorrência de freemartinismo em ovino Santa Inês

This study reports a case of freemartinism of the XX/XY chimera type in a Santa Ines sheep belonging to a property in northeastern Para, Brazil. Discrete masculinization and external genitalia presenting a pseudoprepuce with a hypoplastic penis were observed in vivo. Anatomopathological examination of the internal genitalia showed the absence of a cervix and bilateral presence of an ovary and testis. Variable degrees of epididymal development, accompanied by agenesis of the deferent ducts and other structures arising from the mesonephric ducts, were also observed. Follicular structures, a uterine tubular portion, with marked agenesis and aplasia of the uterine tubes and in some portions of the horns, as well as other parts of paramesonephric structures, were noted in the ovaries. Blood was collected for karyotype analysis and 10 metaphases obtained by short-term lymphocyte culture were examined. Two cell lines were identified: 54,XX (5 cells) and 54,XY (5 cells).

Relata-se um caso de freemartinismo do tipo quimera XX/XY em ovino da raça Santa Inês, proveniente de uma propriedade no Nordeste Paraense (Brasil). In vivo observou-se masculinização discreta, genitália externa apresentando um pseudo-prepúcio com pênis hipoplásico. No exame anatomopatológico verificou-se na genitália interna a ausência de cérvix, ocorrência bilateral de ovário e testículo. Também se observou graus variáveis de desenvolvimento do epidídimo, com considerável agenesia dos ductos deferentes e outras estruturas provenientes dos ductos mesonéfricos. Nos ovários visibilizou-se estruturas foliculares, porção tubular uterina, com maior agenesia e aplasia das tubas uterinas e em algumas porções dos cornos, igualmente como outras partes das estruturas paramesonéfricas. A partir do sangue foi realizado a analise do cariótipo pela analise de dez metáfases, obtidas por cultura temporária de linfócitos, verificando a presença de duas linhagem celulares, sendo 54,XX (5 células) e outra 54,XY (5 células).

Seminoma and sertolioma in a male pseudohermaphrodite dog with unilateral cryptorchidism: short communication / Seminoma e sertolioma em um cão pseudo-hermafrodita masculino e criptorquida unilateral: comunicação científica

A male miniature Schnauzer with cryptorchidism and a mass growth in the right inguinal canal was admitted to the clinical center of a veterinary hospital. During surgical resection of the mass, tubular formations were found, connecting the mass to the left testicle. Histopathology revealed that the tubular formations were uterine tubes and the mass was a seminoma associated with a sertolioma of the right testicle. Further analysis also showed atrophy of the left testicle. Cytogenetic evaluation revealed normal chromosomes of male gender, 78, XY, which led to the conclusion that this was a male pseudohermaphrodite.

Foi atendido na rotina clínica de um hospital veterinário, um cão, macho, da raça Schnauzer, criptorquida com massa em canal inguinal direito. Durante o procedimento cirúrgico para a retirada da massa, foi encontrada uma formação tubular a qual fazia a ligação entre essa massa e o testículo esquerdo. A análise histopatológica concluiu que a formação tubular tratava-se de tubas uterinas, a massa era o testículo direito com seminoma e sertolioma e o testículo esquerdo apresentava atrofia. A avaliação citogenética revelou cromossomos normais, do sexo masculino, 78, XY concluindo que se tratava de um pseudo-hermafrodita masculino.

Seminoma and sertolioma in a male pseudohermaphrodite dog with unilateral cryptorchidism: short communication / Seminoma e sertolioma em um cão pseudo-hermafrodita masculino e criptorquida unilateral: comunicação científica

A male miniature Schnauzer with cryptorchidism and a mass growth in the right inguinal canal was admitted to the clinical center of a veterinary hospital. During surgical resection of the mass, tubular formations were found, connecting the mass to the left testicle. Histopathology revealed that the tubular formations were uterine tubes and the mass was a seminoma associated with a sertolioma of the right testicle. Further analysis also showed atrophy of the left testicle. Cytogenetic evaluation revealed normal chromosomes of male gender, 78, XY, which led to the conclusion that this was a male pseudohermaphrodite.

Foi atendido na rotina clínica de um hospital veterinário, um cão, macho, da raça Schnauzer, criptorquida com massa em canal inguinal direito. Durante o procedimento cirúrgico para a retirada da massa, foi encontrada uma formação tubular a qual fazia a ligação entre essa massa e o testículo esquerdo. A análise histopatológica concluiu que a formação tubular tratava-se de tubas uterinas, a massa era o testículo direito com seminoma e sertolioma e o testículo esquerdo apresentava atrofia. A avaliação citogenética revelou cromossomos normais, do sexo masculino, 78, XY concluindo que se tratava de um pseudo-hermafrodita masculino.