Chemodectoma in a bitch

Background: Chemodectomas, better known as tumors of the base of the heart, arise from aortic bodies, respiratory chemoreceptors located near or inside the aortic arch or originate from receptors located in the carotid arteries. Relatively rare, they affect dogs and, to a lesser extent, cats. They gain great importance when they influence the function of the cardiovascular system, with animals showing clinical signs related to congestive heart failure. Clinical diagnosis is based on symptomatology and complementary tests such as radiography, electrocardiography and echocardiography, while the definitive diagnosis is obtained by cytological and histopathological exams. This study aims to reports a case of malignant chemodectoma in a bitch, whose main symptomatology was neurological and not cardiovascular. Case: A 1-year-old Rottweiler bitch was attended with neurological alterations compatible with vestibular syndrome, hyporexia, dysphagia, apathy, melena, emesis, and purulent nasal discharge on the right nostril. On physical examination, the animal showed depressed level of consciousness, poor body condition, bilateral quemosis, paralysis of the right eye, inspiratory dyspnea and muffling of cardiac auscultation, besides a subcutaneous nodule between the scapulae. On neurological evaluation, horizontal nystagmus, head tilt to the right side, ventromedial strabismus and facial nerve paralysis on the right side were observed so that the localization of the lesion was set in peripheral vestibular system. During anesthesia for esophageal tube placement, a mass from the hard palate to the oropharynx was noted, making endotracheal intubation impossible to perform. Biopsy of this nodule was performed, and tracheostomy was indicated, but the owner opted for euthanasia before the procedure. Necropsy revealed white soft masses in the bilateral retromandibular region, on the subcutaneous tissue near the scapulae, in the right ear and since nasopharynx to the soft palate, in addition to sparse white nodules in the heart, lung, carotid artery, kidneys, right ovary, mesentery near to the spleen, and axillary lymph node. Histologically, the nodules were characterized by neoplastic cells population organized in short bundles or cords, arranged around small blood vessels surrounded by delicate connective tissue. Neoplastic cells infiltrated muscles and blood and lymphatic vessels were filled by multiple neoplastic emboli. The histological pattern of the cells allowed the diagnosis of chemodectoma. Discussion: The bitch from this case had 1-year-old when diagnosed with chemodectoma, differently from most cases from literature, that are between 7 to 15 years old. Furthermore, primarily cardiac tumors are considered rare, being chemodectoma the most common, often reported in Boxer and Boston Terrier dogs, but unusual in Rottweilers. Despites some articles mentioning seizure and Horner's Syndrome secondary to a carotid body chemodectoma, neurological signs are not commonly observed in these cases. The presence of the tumor in the middle ear region of the right side supports the occurrence of peripheral vestibular syndrome and facial nerve paralysis on the same side. Because it is a neoplasm that is usually detected late during the course of the disorder, most patients either cannot obtain diagnosis in vivo, as in this reported animal, which was in such a critical condition that underwent euthanasia, or there are no more possible therapeutic choices. In the patient described, there were numerous metastatic masses and nodules spread throughout the body. Although the typical clinical signs in animals with chemodectomas are often related to heart disease, neurological signs may also be present. This report emphasizes the importance of chemodectoma being included as a differential diagnosis in young dogs and even in breeds such as Rottweiler.

Quimiodectoma em cão / Chemodectoma in a dog

Background: The chemodectoma is a rare neoplasm that originates from chemoreceptors located mainly in the aortic body,and carotid body and sinus, and responsible for detecting variations in blood pH, oxygen pressure and carbon dioxide. Dogsof brachiocephalic breeds and aged between 7 and 15 years have greater propensity. A neoplasm involves infiltrative growthin the vessels at the heart base, which leads to Congestive Heart Failure (CHF). The definitive diagnosis is performed byhistopathological and/or immunohistochemical examination. The aim was to report a case of chemiodectoma in a dog,showing the disease’s clinical characteristics.Case: A 13-year-old male undefined breed dog was examinated in the medical clinic of small animal of Veterinary Hospital,Federal Rural University of Pernambuco (UFRPE) with respiratory effort, hyporexia, and edema in face, cervical, ventralthorax and thoracic limbs, with thirty days evoluted. About physical examination, we observed cachexia, orthopneic position, cyanosis and edema with a positive Godet sign, as well as 8% dehydration degree. Thoracic auscultation presentedmixed dyspnea and muffled heart sounds. Chest radiography detected an radiopacity increase in pulmonary section andmetastatic neoplastic process associated with pleural and pericardial effusion. Fluid therapy with lactated ringer and posteriorthoracentesis in the right hemithorax region was performed for greater respiratory comfort for the patient. Hematologicalcount and biochemical profiles stated normochromic normocytic anemia, relative and absolute lymphopenia, thrombocytopenia, as well as increased alanine aminotransferase (ALT) and aspartate aminotransferase (AST). The patient diedafter 12 hours when was submitted to necroscopic examination and histopathological evaluation. An infiltrative tumor ofcardiac base was observed invading the light of the right atrium, obstructing the venous return, as well as a large thrombus...

Quimiodectoma em cão / Chemodectoma in a dog

Background: The chemodectoma is a rare neoplasm that originates from chemoreceptors located mainly in the aortic body,and carotid body and sinus, and responsible for detecting variations in blood pH, oxygen pressure and carbon dioxide. Dogsof brachiocephalic breeds and aged between 7 and 15 years have greater propensity. A neoplasm involves infiltrative growthin the vessels at the heart base, which leads to Congestive Heart Failure (CHF). The definitive diagnosis is performed byhistopathological and/or immunohistochemical examination. The aim was to report a case of chemiodectoma in a dog,showing the diseases clinical characteristics.Case: A 13-year-old male undefined breed dog was examinated in the medical clinic of small animal of Veterinary Hospital,Federal Rural University of Pernambuco (UFRPE) with respiratory effort, hyporexia, and edema in face, cervical, ventralthorax and thoracic limbs, with thirty days evoluted. About physical examination, we observed cachexia, orthopneic position, cyanosis and edema with a positive Godet sign, as well as 8% dehydration degree. Thoracic auscultation presentedmixed dyspnea and muffled heart sounds. Chest radiography detected an radiopacity increase in pulmonary section andmetastatic neoplastic process associated with pleural and pericardial effusion. Fluid therapy with lactated ringer and posteriorthoracentesis in the right hemithorax region was performed for greater respiratory comfort for the patient. Hematologicalcount and biochemical profiles stated normochromic normocytic anemia, relative and absolute lymphopenia, thrombocytopenia, as well as increased alanine aminotransferase (ALT) and aspartate aminotransferase (AST). The patient diedafter 12 hours when was submitted to necroscopic examination and histopathological evaluation. An infiltrative tumor ofcardiac base was observed invading the light of the right atrium, obstructing the venous return, as well as a large thrombus...(AU)

Development of antennal sensilla of Tetragonisca angustula Latreille, 1811 (Hymenoptera: Meliponini) during pupation / Desenvolvimento das sensilas antenais de Tetragonisca angustula latreille, 1811 (Hymenoptera: Meliponini) durante a pupação

The antennal sensilla are sensory organs formed by a group of neurons and accessory cells, which allow perception of environmental cues, which play a role as mechanoreceptors and chemoreceptors. This study describes the post-embryonic development of the antennal sensilla of the stingless Tetragonisca angustula (Hymenoptera: Meliponini) workers. The development of the antennal sensilla begins in the transition stage of the pre-pupae to white-eyed pupae. The sensilla are completely developed at the black-eyed pupae stage, but they are covered by the old cuticle. The sensilla are exposed to the environment only in newly emerged workers of T. angustula, but it is possible that environmental stimuli can be recognized due to the pores in the old cuticle.(AU)

As sensilas antenais são órgãos sensoriais formados por um conjunto de neurônios que captam estímulos ambientais e células acessórias, desempenhando as funções de mecanorreceptores e quimiorrecepterores. Este trabalho descreve o desenvolvimento pós-embrionário das sensilas antenais de operárias das abelhas sem ferrão Tetragonisca angustula (Hymenoptera: Meliponini). O desenvolvimento das sensilas tem início na transição de pré-pupa para pupa de olho branco e estão completamente desenvolvidas no estágio de pupa de olho preto, mas ainda estão cobertas pela cutícula velha. As sensilas estão completamente expostas em operárias recém-emergidas de T. angustula, mas é possível que estímulos ambientais sejam percebidos em estágios anteriores devido aos poros presentes na cutícula velha.(AU)

Quimiodectoma em equino: relato de caso / Chemodectoma in equine: case report / Quimiodectoma en equina: presentación de un caso

O quimiodectoma corresponde à neoplasia dos quimiorreceptores periféricos que detectam alterações de pH, temperatura e pressões parciais de O2 e CO2 na corrente sanguínea. A partir desta detecção, esses transmitem impulsos nervosos para os centros cerebrais respiratórios e cardíacos para promoção da homeostase, através do sistema nervoso autônomo. Em levantamento bibliográfico há relato de apenas dois casos em equinos, um no corpo aórtico de uma fêmea de 5 anos e em um macho castrado de 13 anos de idade. O objetivo do presente trabalho é relatar um caso de quimiodectoma em equino diagnosticado em necropsia no Hospital Veterinário de Uberaba.(AU)

The chemodectoma corresponds to the peripheral chemoreceptors neoplasia which detect changes in pH, temperature and partial pressures of 02 and C02 in the bloodstream. From this detection, these transmit nerve impulses to the brain respiratory and cardiac centers to promote homeostasis, through the autonomic nervous system. In literature there are reports of only two cases in horses, one in aortic body of a female of 5 years and in a castrated male 13 years old. The aim of this study is to report a case of chemodectomaequinus diagnosed at autopsy at the Veterinary Hospital of Uberaba.(AU)

El quimiodectoma corresponde a la neoplasia de los quimiorreceptores periféricos que detectan alteraciones de pH, temperatura y presiones parciales de O2 y CO2 en la corrí ente sanguínea. A partir de esta detección, estos transmiten impulsos nerviosos para los centros cerebrales, respiratorios y cardíacos para promoción de la homeostase, através del sistema nervioso autónomo. En el levantamiento bibliográfico, hay relatos de apenas dos casos en equinos, uno en el cuerpo aórtico de una hembra de 5 anos yotro en un macho castrado de 13 anos de edad. El objetivo del presente trabajo es relatar un caso de quimiodectoma en equino diagnosticado en necropsia en el Hospital Veterinário de Uberaba.(AU)

Quimiodectoma em equino: relato de caso / Chemodectoma in equine: case report / Quimiodectoma en equina: presentación de un caso

O quimiodectoma corresponde à neoplasia dos quimiorreceptores periféricos que detectam alterações de pH, temperatura e pressões parciais de O2 e CO2 na corrente sanguínea. A partir desta detecção, esses transmitem impulsos nervosos para os centros cerebrais respiratórios e cardíacos para promoção da homeostase, através do sistema nervoso autônomo. Em levantamento bibliográfico há relato de apenas dois casos em equinos, um no corpo aórtico de uma fêmea de 5 anos e em um macho castrado de 13 anos de idade. O objetivo do presente trabalho é relatar um caso de quimiodectoma em equino diagnosticado em necropsia no Hospital Veterinário de Uberaba.

The chemodectoma corresponds to the peripheral chemoreceptors neoplasia which detect changes in pH, temperature and partial pressures of 02 and C02 in the bloodstream. From this detection, these transmit nerve impulses to the brain respiratory and cardiac centers to promote homeostasis, through the autonomic nervous system. In literature there are reports of only two cases in horses, one in aortic body of a female of 5 years and in a castrated male 13 years old. The aim of this study is to report a case of chemodectomaequinus diagnosed at autopsy at the Veterinary Hospital of Uberaba.

El quimiodectoma corresponde a la neoplasia de los quimiorreceptores periféricos que detectan alteraciones de pH, temperatura y presiones parciales de O2 y CO2 en la corrí ente sanguínea. A partir de esta detección, estos transmiten impulsos nerviosos para los centros cerebrales, respiratorios y cardíacos para promoción de la homeostase, através del sistema nervioso autónomo. En el levantamiento bibliográfico, hay relatos de apenas dos casos en equinos, uno en el cuerpo aórtico de una hembra de 5 anos yotro en un macho castrado de 13 anos de edad. El objetivo del presente trabajo es relatar un caso de quimiodectoma en equino diagnosticado en necropsia en el Hospital Veterinário de Uberaba.