Intra-abdominal torsion of a non-neoplastic cryptorchid testis in an adult dog / Torção intra-abdominal de testículo criptorquideo sem neoplasia em cão adulto

Intra-abdominal or intrascrotal testicular torsion in dogs occurs due to spermatic cord rotation. Dogs with testicular torsion commonly present severe pain and require surgical intervention. Torsion of intra-abdominal retained testicles in cryptorchid adult dogs is often associated with the presence of testicular neoplasia. Herein, we reported the case of a 5-year-old male poodle with uncommon intra-abdominal testicular torsion (ITT) of a non-neoplastic testicle. The dog was referred to the veterinary hospital with acute abdominal pain in the hypogastric region. An intra-abdominal gonad and alterations compatible with testicular torsion were visualized during ultrasound examination. Orchiectomy and histopathological analysis of the testes confirmed the diagnosis of ITT in the absence of neoplasia. The patient recovered uneventfully from the situation. This report showed that ITT can occur in adult dogs in the absence of testicular neoplasia and reinforce the message that it should be included as a differential diagnosis in cases of acute abdominal pain in cryptorchid dogs. Furthermore, the ultrasound examination in this case of pain in the hypogastric region was decisive for the diagnosis of ITT.

A torção testicular intra-abdominal ou intra-escrotal em cães ocorre devido à rotação do cordão espermático. Os cães com torção testicular apresentam comumente dor intensa e necessitam de intervenção cirúrgica. Em cães adultos, a torção de testículos retidos no abdômen está geralmente associada à presença de neoplasia testicular. Este relato descreve um caso incomum de cão macho, de cinco anos de idade, da raça Poodle, encaminhado ao Hospital Veterinário com dor abdominal aguda na região hipogástrica. Durante o exame ecográfico, foi possível evidenciar um testículo e alterações compatíveis com torção testicular. A orquiectomia intra-abdominal e posterior análise histopatológica confirmaram a ITT sem neoplasia associada. O paciente apresentou evolução clínica satisfatória. Este relato mostra que a ITT na ausência de neoplasia pode ocorrer em cães adultos, reforçando a mensagem de que deve ser considerada como um diferencial diagnóstico em casos de dor abdominal aguda. Além disso, o exame ultrassonográfico realizado neste caso de dor na região hipogástrica foi decisivo para o diagnóstico de ITT.

Gender-based incidence, recovery period, and mortality rate of COVID-19 among the population of district Attock, Pakistan / Incidência baseada em gênero, período de recuperação e taxa de mortalidade de COVID-19 entre a população do distrito de Attock, Paquistão

COVID-19 is reported as an extremely contagious disease with common symptoms of fever, dry cough, sore throat, and tiredness. The published literature on incidence and gender-wise prevalence of COVID-19 is scarce in Pakistan. Therefore, the present study was designed to compare the distribution, incubation period and mortality rate of COVID-19 among the male and female population of district Attock. The data were collected between 01 April 2020 and 07 December 2020 from the population of district Attock, Pakistan. A total of 22,962 individuals were screened and 843 were found positive for RT-qPCR for SARS-CoV-2. The confirmed positive cases were monitored carefully. Among the positive cases, the incidence of COVID-19 was 61.7% among males and 38.2% among females. The average recovery period of males was 18.89±7.75 days and females were 19±8.40 days from SARS-CoV-2. The overall mortality rate was 8.06%. The death rate of male patients was significantly higher (P<0.05) compared to female patients. Also, the mortality rate was higher (P<0.05) in male patients of 40-60 years of age compared to female patients of the same age group. Moreover, the mortality rate significantly increased (P<0.05) with the increase of age irrespective of gender. In conclusion, the incidence and mortality rate of COVID-19 is higher in males compared to the female population. Moreover, irrespective of gender the mortality rate was significantly lower among patients aged <40 years.

Covid-19 é relatada como uma doença extremamente contagiosa com sintomas comuns de febre, tosse seca, dor de garganta e cansaço. A literatura publicada sobre incidência e prevalência de Covid-19 com base no gênero é escassa no Paquistão. Portanto, o presente estudo teve como objetivo comparar a distribuição, o período de incubação e a taxa de mortalidade de Covid-19 entre a população masculina e feminina do distrito de Attock. Os dados foram coletados entre 1 de abril de 2020 e 7 de dezembro de 2020 da população do distrito de Attock, Paquistão. Um total de 22.962 indivíduos foi selecionado, e 843 foram considerados positivos para RT-qPCR para SARS-CoV-2. Os casos positivos confirmados foram monitorados cuidadosamente. Entre os casos positivos, a incidência de Covid-19 foi de 61,7% no sexo masculino e 38,2% no feminino. O período médio de recuperação dos homens foi de 18,89 ± 7,75 dias e das mulheres 19 ± 8,40 dias do SARS-CoV-2. A mortalidade geral foi de 8,06%. A taxa de mortalidade de pacientes do sexo masculino foi significativamente maior (P < 0,05) em comparação com pacientes do sexo feminino. Além disso, a taxa de mortalidade foi maior (P < 0,05) em pacientes do sexo masculino com 40-60 anos de idade em comparação com pacientes do sexo feminino da mesma faixa etária. Além disso, a taxa de mortalidade aumentou significativamente (P < 0,05) com o aumento da idade, independentemente do sexo. Em conclusão, a incidência e a taxa de mortalidade de Covid-19 são maiores no sexo masculino em comparação com a população feminina. E também, independentemente do sexo, a taxa de mortalidade foi significativamente menor entre os pacientes com idade < 40 anos.

Gender-based incidence, recovery period, and mortality rate of COVID-19 among the population of district Attock, Pakistan / Incidência baseada em gênero, período de recuperação e taxa de mortalidade de COVID-19 entre a população do distrito de Attock, Paquistão

COVID-19 is reported as an extremely contagious disease with common symptoms of fever, dry cough, sore throat, and tiredness. The published literature on incidence and gender-wise prevalence of COVID-19 is scarce in Pakistan. Therefore, the present study was designed to compare the distribution, incubation period and mortality rate of COVID-19 among the male and female population of district Attock. The data were collected between 01 April 2020 and 07 December 2020 from the population of district Attock, Pakistan. A total of 22,962 individuals were screened and 843 were found positive for RT-qPCR for SARS-CoV-2. The confirmed positive cases were monitored carefully. Among the positive cases, the incidence of COVID-19 was 61.7% among males and 38.2% among females. The average recovery period of males was 18.89±7.75 days and females were 19±8.40 days from SARS-CoV-2. The overall mortality rate was 8.06%. The death rate of male patients was significantly higher (P<0.05) compared to female patients. Also, the mortality rate was higher (P<0.05) in male patients of 40-60 years of age compared to female patients of the same age group. Moreover, the mortality rate significantly increased (P<0.05) with the increase of age irrespective of gender. In conclusion, the incidence and mortality rate of COVID-19 is higher in males compared to the female population. Moreover, irrespective of gender the mortality rate was significantly lower among patients aged <40 years.(AU)

Covid-19 é relatada como uma doença extremamente contagiosa com sintomas comuns de febre, tosse seca, dor de garganta e cansaço. A literatura publicada sobre incidência e prevalência de Covid-19 com base no gênero é escassa no Paquistão. Portanto, o presente estudo teve como objetivo comparar a distribuição, o período de incubação e a taxa de mortalidade de Covid-19 entre a população masculina e feminina do distrito de Attock. Os dados foram coletados entre 1 de abril de 2020 e 7 de dezembro de 2020 da população do distrito de Attock, Paquistão. Um total de 22.962 indivíduos foi selecionado, e 843 foram considerados positivos para RT-qPCR para SARS-CoV-2. Os casos positivos confirmados foram monitorados cuidadosamente. Entre os casos positivos, a incidência de Covid-19 foi de 61,7% no sexo masculino e 38,2% no feminino. O período médio de recuperação dos homens foi de 18,89 ± 7,75 dias e das mulheres 19 ± 8,40 dias do SARS-CoV-2. A mortalidade geral foi de 8,06%. A taxa de mortalidade de pacientes do sexo masculino foi significativamente maior (P < 0,05) em comparação com pacientes do sexo feminino. Além disso, a taxa de mortalidade foi maior (P < 0,05) em pacientes do sexo masculino com 40-60 anos de idade em comparação com pacientes do sexo feminino da mesma faixa etária. Além disso, a taxa de mortalidade aumentou significativamente (P < 0,05) com o aumento da idade, independentemente do sexo. Em conclusão, a incidência e a taxa de mortalidade de Covid-19 são maiores no sexo masculino em comparação com a população feminina. E também, independentemente do sexo, a taxa de mortalidade foi significativamente menor entre os pacientes com idade < 40 anos.(AU)

Gender-based incidence, recovery period, and mortality rate of COVID-19 among the population of district Attock, Pakistan / Incidência baseada em gênero, período de recuperação e taxa de mortalidade de COVID-19 entre a população do distrito de Attock, Paquistão

Abstract COVID-19 is reported as an extremely contagious disease with common symptoms of fever, dry cough, sore throat, and tiredness. The published literature on incidence and gender-wise prevalence of COVID-19 is scarce in Pakistan. Therefore, the present study was designed to compare the distribution, incubation period and mortality rate of COVID-19 among the male and female population of district Attock. The data were collected between 01 April 2020 and 07 December 2020 from the population of district Attock, Pakistan. A total of 22,962 individuals were screened and 843 were found positive for RT-qPCR for SARS-CoV-2. The confirmed positive cases were monitored carefully. Among the positive cases, the incidence of COVID-19 was 61.7% among males and 38.2% among females. The average recovery period of males was 18.89±7.75 days and females were 19±8.40 days from SARS-CoV-2. The overall mortality rate was 8.06%. The death rate of male patients was significantly higher (P<0.05) compared to female patients. Also, the mortality rate was higher (P<0.05) in male patients of 40-60 years of age compared to female patients of the same age group. Moreover, the mortality rate significantly increased (P<0.05) with the increase of age irrespective of gender. In conclusion, the incidence and mortality rate of COVID-19 is higher in males compared to the female population. Moreover, irrespective of gender the mortality rate was significantly lower among patients aged <40 years.

Resumo Covid-19 é relatada como uma doença extremamente contagiosa com sintomas comuns de febre, tosse seca, dor de garganta e cansaço. A literatura publicada sobre incidência e prevalência de Covid-19 com base no gênero é escassa no Paquistão. Portanto, o presente estudo teve como objetivo comparar a distribuição, o período de incubação e a taxa de mortalidade de Covid-19 entre a população masculina e feminina do distrito de Attock. Os dados foram coletados entre 1 de abril de 2020 e 7 de dezembro de 2020 da população do distrito de Attock, Paquistão. Um total de 22.962 indivíduos foi selecionado, e 843 foram considerados positivos para RT-qPCR para SARS-CoV-2. Os casos positivos confirmados foram monitorados cuidadosamente. Entre os casos positivos, a incidência de Covid-19 foi de 61,7% no sexo masculino e 38,2% no feminino. O período médio de recuperação dos homens foi de 18,89 ± 7,75 dias e das mulheres 19 ± 8,40 dias do SARS-CoV-2. A mortalidade geral foi de 8,06%. A taxa de mortalidade de pacientes do sexo masculino foi significativamente maior (P < 0,05) em comparação com pacientes do sexo feminino. Além disso, a taxa de mortalidade foi maior (P < 0,05) em pacientes do sexo masculino com 40-60 anos de idade em comparação com pacientes do sexo feminino da mesma faixa etária. Além disso, a taxa de mortalidade aumentou significativamente (P < 0,05) com o aumento da idade, independentemente do sexo. Em conclusão, a incidência e a taxa de mortalidade de Covid-19 são maiores no sexo masculino em comparação com a população feminina. E também, independentemente do sexo, a taxa de mortalidade foi significativamente menor entre os pacientes com idade < 40 anos.

Continuous infusion of dipyrone in bitches in the intraoperative period: cardiorespiratory effects / Infusão continua transoperatória de dipirona em cadelas: efeitos cardiorrespiratórios e analgésicos

Dipyrone is an effective analgesic for managing moderate or severe postoperative pain and can be used alone for mild pain or in combination with other analgesics for any type of pain. This study aimed to examine the administration of dipyrone by continuous infusion (CI) as an adjuvant analgesic in the intraoperative period for bitches undergoing elective ovariohysterectomy (OH) and its effect on these patients' cardiorespiratory parameters. Twenty bitches underwent an elective OH procedure. The pre-anesthetic agent was a combination of acepromazine and morphine. Propofol was used to induce anesthesia, and isoflurane was used for maintenance. Subsequently, the animals were randomly allocated into two groups: the dipyrone group (DG) received a bolus dose of dipyrone (25 mg kg-1) by CI at a rate of 10 mg kg-1 h, and the control group (CG) received a bolus dose and a CI of 0.9% NaCl solution, both groups at a rate of 5 mL kg-1 h. The parametric variables were analyzed by ANOVA, followed by Tukey's test (p <0.05). The paired t-test (p <0.05) was used for comparison between the groups. Statistical differences were observed for heart rate, systolic, diastolic, and mean arterial pressure, respiratory rate, and blood glucose between the periods in both groups. There were differences only in the basal values of MAP between the groups; however, most values remained within the physiological range for the species. Using the drug as an adjuvant to anesthesia did not alter cardiorespiratory parameters, and it can be used as an adjuvant in analgesia during the intraoperative period of OH.(AU)

A dipirona é um analgésico eficaz para o manejo da dor pós-operatória moderada ou grave, podendo ser utilizada isoladamente em dores leves ou associada a outros analgésicos em qualquer tipo de dor. O presente estudo teve como objetivo avaliar a utilização de infusão contínua (IC) de dipirona no período transoperatório de cadelas submetidas à Ovariohisterectomia (OH) eletiva como adjuvante analgésico, avaliando seu efeito sobre parâmetros cardiorrespiratórios desses pacientes. Para o estudo, 20 cadelas foram submetidas ao procedimento de OH eletiva. A medicação pré-anestésica foi composta pela associação de acepromazina e morfina, seguida da indução com propofol e manutenção com isofluorano. Posteriormente, os animais foram alocados, aleatoriamente, em dois grupos: dipirona (GD), que receberam bolus de dipirona (25 mg kg-1) seguido da IC do fármaco na taxa de 10 mg kg-1 h, e grupo controle (GC), cujos animais receberam o bolus e IC de solução de NaCl 0,9%, ambos os grupos na velocidade de 5 mL kg-1 h. Variáveis paramétricas foram analisadas pela ANOVA seguida pelo teste de Tukey (p <0,05) e comparadas entre os grupos pelo teste t pareado (p <0,05). Foram observadas diferenças estatísticas entre os momentos em ambos os grupos em relação à FC, FR, PAS, PAM, PAD e glicemia. Entre os grupos, houve apenas diferenças nos valores basais de PAM, no entanto, a maioria dos valores manteve-se dentro da faixa considerada fisiológica para a espécie. A utilização do fármaco como adjuvante a anestesia não alterou os parâmetros cardiorrespiratórios, podendo ser utilizado como adjuvante na analgesia durante o transoperatório de OH.(AU)

Assessment of general activity and anxiety-like behavior in mice following tramadol and meloxicam administration for managing immediate post-operative pain

After analgesic administration, we evaluated general activity in the Open-Field and anxiety-like behavior in the Elevated Plus Maze of vasectomized mice. We divided C57BL/6J male mice into eight groups: saline, three non-operated control groups treated with 10 mg/kg meloxicam, 20 mg/kg tramadol, or both intraperitoneally, and four vasectomized mice groups treated with the same analgesic protocol as the control groups. One group of vasectomized mice received both treatments and an additional 10 mg/kg lidocaine at the incision site. We conducted the vasectomy via scrotal approach under isoflurane inhalation anesthesia and performed behavioral tests after full anesthesia recovery. Mice treated with meloxicam demonstrated low ambulation, spontaneous activity, and rearing frequency. Mice treated with tramadol showed spontaneous behavior compared with the saline control. Due to behavior changes demonstrated by meloxicam controls, we were unable to identify whether meloxicam provided adequate analgesia. Vasectomized mice treated with tramadol showed general activity behavior similar to their control but displayed significantly less rearing, suggesting that they were under potential signs of pain or discomfort. In conclusion, the Open Field test and the Elevated Plus Maze can usefully pre-evaluate analgesic protocols to identify possible interference caused by adverse drug effects. For future directions, an appropriate regimen of meloxicam and tramadol for enhancing mice welfare post vasectomy should be better investigated.

Focal spinal hyperesthesia as a prognostic factor in paraplegic dogs without deep pain perception / Hiperestesia espinhal focal como fator prognóstico em cães paraplégicos sem percepção de dor profunda

Intervertebral disc extrusion (IVDE) is the most common cause of spinal cord compression in dogs, whose prognosis is variable and depends on several factors, with deep pain perception (DPP) being the main parameter used. Investigations of new prognostic factors are studied to assist in the estimation of functional recovery. Thus, this study aimed to evaluate whether spinal hyperesthesia (SH) at the compression site can be used as a prognostic factor for the functional recovery of dogs with acute IVDE (Hansen type I), without DPP being subjected to thoracolumbar hemilaminectomy. Decompression surgery was performed on the same day or the day after admission. The duration of the loss of DPP until surgery performance ranged from 1 to 60 days, with a median of 4.5 days for the group of dogs with SH and 5.5 days for those without SH. Among the 68 dogs included in this retrospective study, 73.5% (50/68) showed SH, and 26.5% (18/68) were not identified. Recovery was satisfactory in 60% (30/50) of dogs with SH and in 27.7% (5/18) of dogs without SH, demonstrating that paraplegic dogs without DPP but with SH were 3.9 times more likely to recover when compared to dogs in the same condition, but with no SH. No studies have evaluated SH by palpation of the spine as a prognostic factor, which reinforces the relevance of the present study. The results of this study imply that SH in paraplegic dogs affected by thoracolumbar IVDE, without the presence of DPP, can be used as a possible prognostic indicator of functional recovery.

A extrusão do disco intervertebral (EDIV) é a causa mais comum de lesão compressiva na medula espinhal de cães, cujo prognóstico é variável e depende de diversos fatores, sendo a percepção de dor profunda (PDP) o principal parâmetro utilizado. Pesquisas de novos fatores prognósticos são estudados com intuito de auxiliar na estimativa mais precisa de recuperação funcional. Com isso, o objetivo do estudo foi avaliar se a hiperestesia espinhal (HE) no local da compressão, pode ser utilizada como um fator prognóstico para recuperação funcional de cães com extrusão aguda do disco intervertebral (Hansen tipo I), sem a presença de PDP submetidos a hemilaminectomia toracolombar. A cirurgia descompressiva ocorreu no mesmo dia ou no dia seguinte ao atendimento. A duração da perda de dor profunda até a realização da cirurgia variou de 1 a 60 dias, com uma mediana de 4,5 dias para o grupo de cães com e 5,5 dias para aqueles sem hiperestesia espinhal. Dos 68 cães incluídos nesse estudo retrospectivo, 73,5% (50/68) apresentavam HE e, em 26,5% (18/68) a dor não foi identificada. A recuperação foi satisfatória nos cães com HE em 60% (30/50) e, sem HE, em 27,7% (5/18) dos casos, demonstrando que os cães paraplégicos sem PDP, mas com presença de hiperestesia espinhal tem 3,9 vezes mais chances de recuperação quando comparado com cães na mesma condição, mas sem HE. Não foram encontrados trabalhos que avaliaram a HE mediante a palpação da coluna vertebral como um fator prognóstico, o que reforça a relevância do presente estudo. Os resultados do presente trabalho sugerem que a HE em cães paraplégicos acometidos por EDIV toracolombar sem presença de PDP pode ser utilizada como um possível indicador prognóstico de recuperação funcional.

Associação do bloqueio do plano transverso e serrátil em gata submetida à mastectomia / Association of transversus and serratus plane block in cat submitted to mastectomy

Os bloqueios locorregionais são considerados padrão-ouro para a analgesia perioperatória. Sendo assim, este trabalho apresenta o efeito da associação do bloqueio do plano transverso do abdome com o bloqueio do plano serrátil em um felino de 11 anos, fêmea, que foi submetido à mastectomia unilateral. Foi utilizada a metadona 0,3 mg/kg via intramuscular (IM) na medicação pré-anestésica e propofol dose-efeito via intravenosa (IV) para indução, enquanto a manutenção foi feita com isoflurano. O TAP Block e o SP-Block foram realizados unilateralmente utilizando a associação de bupivacaína 0,3mL/kg, em cada ponto, diluída a 0,25% com solução fisiológica. A frequência cardíaca (FC), a frequência respiratória (f), a pressão arterial não invasiva (Método Doppler), a temperatura esofágica (oC), a saturação de oxigênio (SpO2), a capnografia (EtCO2) e o eletrocardiograma foram monitorados continuamente e registrados a cada dez minutos. A paciente foi monitorada por cinco horas, após a extubação, quanto à dor, sendo utilizada, para isso, a Escala Multidimensional de Dor Aguda (UNESP-Botucatu). A recuperação anestésica da paciente foi rápida e sem complicações. Durante a avaliação de dor, o animal apresentou escore zero, não manifestando qualquer desconforto pós-operatório. A associação das técnicas foi eficaz no bloqueio anestésico das paredes torácica e abdominal, sugerindo a inclusão destas nos protocolos de analgesia multimodal para esse tipo de cirurgia.

Locoregional blocks are considered the gold standard for perioperative analgesia. Thus, this paper presents the effect of the association of transverse abdominal plane block with serratus plane block in an 11-year-old female feline submitted to unilateral mastectomy. Methadone 0.3 mg/kg via intramuscular (IM) was used as pre anesthetic medication and dose-effect propofol via intravenous (IV) was used for induction, while the maintenance was done with isofluorane. TAP Block and SP-Block were performed unilaterally using an association of Bupivacaine 0.3 ml/kg at each point, diluted to 0.25% with saline solution. Heart rate (HR), respiratory rate (f), non-invasive blood pressure (Doppler method), esophageal temperature (oC), oxygen saturation (SpO2), capnography (EtCO2), and electrocardiogram were monitored continuously and recorded every 10 minutes. The patient was monitored for pain during five hours after extubation using the Multidimensional Scale of UNESP-Botucatu. The anesthetic recovery of the patient was fast and without complications. During pain assessment, the animal presented a score of zero and did not present any postoperative discomfort. The association of techniques was effective in the anesthetic blockade of the thoracic and abdominal walls, suggesting their inclusion in multimodal analgesia protocols for this type of surgery.

Infusão contínua de fentanil e cetamina para controle de dor no transcirurgico: relato de caso / Continuous infusion of fentanyl and ketamine for trans-surgical pain control: case report

O paciente da espécie canina, sem raça definida, com 5 anos, deu entrada a clínica veterinária particular apresentando quadro de dor aguda e intensa em cavidade abdominal associada a prostração. Foram realizados exames de sangue, ultrassonografia e radiografia de abdômen, cuja suspeita foi torção parcial do estômago, com esplenomegalia, além de gastrite e enterite. O paciente foi submetido imediatamente ao procedimento cirúrgico para alívio, reposicionamento do órgão e gastropexia. O animal foi medicado previamente com metadona, tramadol e dipirona duas horas antes do ato cirúrgico, portanto não foram utilizadas medicações pré-anestésicas e optou-se pelo propofol e cetamina para a indução anestésica, além da infusão contínua com cetamina e fentanil para se obter a analgesia multimodal. Os parâmetros de dor foram avaliados por meio das frequências cardíaca e respiratória, traçado eletrocardiográfico, pressão arterial sistólica e média, aferição da temperatura retal e coloração de mucosas, a cada 5 minutos. Os mesmos indicaram boa estabilidade hemodinâmica, segurança e analgesia, sem necessidade de alterar as doses estabelecidas durante o procedimento. Pode ser observada também redução do requerimento de isoflurano para manutenção do plano cirúrgico. O paciente acordou sem sinais de dor no pós-operatório imediato evitando estresse sistêmico, o que conferiu o bom resultado do protocolo analgésico instituído.

The patient (Caramel) canine, mixed breed, approximately 5 years old, weighing 26kg was seen at the Ame Vet veterinary clinic, with severe abdominal pain, apathy, anorexia, prostration. Blood tests, abdominal ultrasound and abdominal x-ray were performed according to the tests a suspicion of partial torsion of the stomach and splenomegaly with right displacement, in addition to gastritis and enteritis. It was decided by the clinic and surgeon to perform laparotomy and prophylactic gastropexy. The animal was previously medicated by the clinic that treated the animal for analgesia with methadone, tramadol and dipyrone two hours before the beginning of the surgical procedure, therefore, pre-anesthetic medications, anesthetic induction with propofol, and ketamine were not used, aiming to perform analgesia. Multimodal with continuous infusion of ketamine and fentanyl, that is, more than one different mechanism of action, acting synergistically and reducing dose-dependent adverse effects and monitoring hemostasis and patient parameters, presenting its efficacy and safety in intraoperative pain control. The parameters addressed were heart rate (HR), respiratory rate (RR), electrocardiographic tracing, Spo2, systolic blood pressure (SBP), mean arterial pressure (MAP), temperature and mucosal color, evaluated every 5 minutes. The parameters evaluated indicated good hemodynamic stability, safety and analgesia, with no need to change the doses established during the procedure. A reduction in the requirement of isoflurane to maintain the surgical plan can also be observed. The patient woke up without signs of pain in the immediate postoperative period, thus avoiding systemic stress. which conferred the good result of the analgesic protocol instituted.

Bloqueio do plano serrátil associado ao transverso do abdômen na mastectomia total unilateral em cadela / Blocking of the Serratus Plan associated with the Transverse Abdominis in a total unilateral mastectomy in bitch

A anestesia locorregional, em pequenos animais, está em crescente utilização como forma de promover analgesia para procedimentos cirúrgicos, através do bloqueio reversível da condução do impulso nervoso. Assim, o objetivo deste trabalho foi relatar o uso do bloqueio locorregional do plano serrátil (SP block) associado ao bloqueio locorregional do plano transverso do abdômen (TAP block) em uma cadela da raça Lhasa Apso. A associação de tais bloqueios visou à insensibilização da musculatura na região da cadeia mamária para um procedimento cirúrgico de mastectomia unilateral total. A cadela castrada, foi encaminhada para a mastectomia unilateral total direita, apresentando nódulos nas glândulas mamárias torácica caudal e inguinal. Os bloqueios foram realizados com a paciente em decúbito dorsal, utilizando-se bupivacaína a 0,25%. Em seguida, a paciente foi liberada para o procedimento, o qual foi monitorado. Os parâmetros de eletrocardiografia, frequência respiratória, frequência cardíaca, oximetria de pulso, pressão arterial oscilométrica (composta por pressão arterial sistólica, pressão arterial diastólica e pressão arterial média), capnografia e temperatura esofágica foram anotados a cada dez minutos em uma ficha de avaliação anestésica. Durante a recuperação pós-operatória, foi realizada a avaliação de dor aguda por meio da escala de dor da Universidade de Melbourne. Os resultados demonstram que a associação do TAP block com o SP block foi eficiente em promover analgesia para uma mastectomia total unilateral de cadela.

Locoregional anesthesia in small animals is increasingly used as a way to promote analgesia for surgical procedures, through a reversible block of nerve impulse conduction. Thus, the objective of this study was to report the use of locoregional block of the serratus plane (SP block) associated with the locoregional block of the transverse abdominis plane (TAP block) in a bitch of the Lhasa Apso breed. The association of such blocks aimed to desensitize the musculature in the region of the mammary chain for a surgical procedure of total unilateral mastectomy. The castrated bitch was referred for total right unilateral mastectomy, showing nodules in the caudal thoracic and inguinal mammary glands. The blocks were performed with the patient in dorsal decubitus, using 0.25% bupivacaine. Then, the patient was released for the procedure, which was monitored. The parameters of electrocardiography, respiratory rate, heart rate, pulse oximetry, oscillometric blood pressure (composed of systolic blood pressure, diastolic blood pressure, and mean blood pressure), capnography, and esophageal temperature were recorded every 10 minutes in an anesthetic evaluation form. During the postoperative recovery, acute pain was evaluated using the pain scale of the University of Melbourne. The results demonstrate that the association of TAP block with SP block was efficient in promoting analgesia for a total unilateral mastectomy in a bitch.

Estabilização de ombro em um gato ­ Relato de caso / Shoulder estabilization in a cat ­ Case report

A estabilidade da articulação do ombro é garantida por ligamentos, cápsula articular, tendões e músculos, contudo traumas podem causar falência dos mecanismos estabilizadores, com consequente luxação ou instabilidade articular. Objetivou-se relatar o caso de instabilidade medial e lateral de ombro direito em felino sem raça definida, atendido com queixa de claudicação aguda de membro torácico secundária a trauma por confronto com outro animal. Inicialmente foi realizado tratamento clínico por meio de imobilização articular. Contudo, devido ao insucesso da técnica, procedeu-se para o tratamento cirúrgico de estabilização articular com prótese ligamentar sintética. No pós-operatório imediato, evidenciou-se ausência de crepitações e instabilidade articular. Após oito dias da cirurgia, o paciente apresentou retorno total às funções de apoio do membro e sem sinais de dor ou redução de movimentos. Concluiu-se que, embora de reduzida ocorrência, a instabilidade de origem traumática do ombro configura-se como um diferencial para claudicação aguda de membro torácico e que o tratamento cirúrgico pode ser necessário, mostrando-se eficiente na resolução de tais casos com o acesso e técnica de estabilização propostos.

The stability of the shoulder joint is granted by ligaments, joint capsule, tendons and muscles. However, traumatic injuries can cause failure of the stabilization mechanisms, which leads to articular luxation or instability. The aim of the paper is to report a case of medial and lateral right shoulder joint instability in a mixed-breed cat, presenting acute forelimb lameness after a fight trauma with another cat. Initially, it was recommended a conservative treatment through articular immobilization. However, the technique was unsuccessful, and the surgery treatment was performed, to stabilize the joint with synthetic ligament prosthetic. In the postoperative period, no crepitation or instability were identified. After eight days of surgery, the patient returned totally to the normal function of the forelimb, without movement restriction or pain. It was concluded that, although rare, the traumatic shoulder joint instability is a differential diagnosis for acute forelimb lameness and the surgical treatment can be necessary, showing a good result in the resolution of these injuries with the surgical approach and stabilization method proposed.

Postoperative evaluation of analgesia promoted by the use of dexmedetomidine alone and associated with morphine as an intramuscular pre-anesthetic medication in bitches submitted for ovariohysterectomy / Avaliação pós-operatória da analgesia promovida pelo uso da dexmedetomidina isolada e associada à morfina em cadelas submetidas à ovariohisterectomia

This study aimed to evaluate the postoperative analgesic efficacy of dexmedetomidine alone and when associated with morphine in patients under general inhalational anesthesia with isoflurane and undergoing elective ovariohysterectomy (OH). Twenty healthy bitches were selected via physical and laboratory examinations. Prior to the study, they underwent a 24-h period of adaptation to the environment and observers. They were then randomly divided into two groups: the dexmedetomidine group receiving a dose of 10 µg/kg, and dexmedetomidine group (10 µg/kg) associated with morphine receiving a dose of 0.3 mg/kg, administered via the intramuscular route. Thereafter, patients were induced with propofol and maintained with isoflurane diluted in 100% oxygen administered through a calibrated vaporizer. To verify postoperative analgesia, pain assessments were performed using the modified Glasgow (EGM) and Melbourne (EM) scales. For sedation assessment, the Dobbins scale was used at different times: before the administration of pre-anesthetic medication (T0) and at another six times in the postoperative period, 1 (T1), 2 (T2), 4 (T3), 8 (T4), 12 (T5), and 24 (T6) h after orotracheal extubation. No statistical differences were observed between groups in the scales according to Dunn's Kruskal-Wallis post hoc test, and between the times a statistical difference was noticed by the Friedman test (p<0.05) for the EGM and EM scale scores, but there was no need for analgesic rescue. Therefore, we found that isolated dexmedetomidine and morphine produced adequate analgesic effects in the postoperative period of bitches submitted for OH.

Objetivou-se avaliar a eficácia analgésica pós-operatória da dexmedetomidina isolada e associada à morfina em pacientes submetidas à anestesia geral inalatória com isoflurano e submetidas à ovariohisterectomia eletiva (OH). Vinte cadelas saudáveis foram selecionadas a partir de exames físico e laboratoriais. Previamente ao estudo, foram submetidas a um período de 24 horas de adaptação ao ambiente e aos observadores. Ato contínuo, foram divididas aleatoriamente em dois grupos: grupo dexmedetomidina, na dose de 10 µg/Kg (GD) e grupo dexmedetomidina (10 µg/Kg) associado com morfina, na dose de 0,3 mg/Kg (GDM), administrados pela via intramuscular (IM). Ato contínuo, as pacientes foram induzidas com propofol e mantidas com isoflurano diluído em oxigênio 100% e administrado através de vaporizador calibrado. Para verificação da analgesia pós-operatória foram realizadas avaliações de dor por meio de escalas de Glasgow Modificada (EGM) e de Melbourne (EM). Para avaliação de sedação, por meio da escala de Dobbins (ED), em diferentes tempos: antes da administração da MPA (T0), e em mais 6 tempos no período pós-operatório, uma (T1), duas (T2), quatro (T3), oito (T4), 12 (T5) e 24 (T6) horas após a extubação orotraqueal. Não foram observadas diferenças estatísticas entre os grupos nas escalas de acordo com o teste de Kruskal-Wallis post-hoc de Dunn; e entre os tempos notou-se diferença estatística pelo teste de Friedman (p<0,05) para EGM e EM, porém não houve necessidade de resgate analgésico. Portanto, conclui-se que a dexmedetomidina isolada e associada a morfina produziu efeito analgésico adequado no período pós-operatório de cadelas submetidas a OH.

Comparison of intraoperative nociception and postoperative acute pain after traditional or minimally invasive ovariohysterectomy in dogs

Many variations of ovariohysterectomy techniques have been described, including the traditional one and minimally invasive procedures. Non-laparoscopic Snook hook technique is an alternative for performing minimally invasive ovariohysterectomy. Few studies have been carried out in order to assess pain in animals submitted to minimally invasive surgeries, especially involving one of the most performed surgical procedures in veterinary practice. The aim of this study was to evaluate surgical duration, intraoperative nociception and acute postoperative pain after traditional ovariohysterectomy or minimally invasive non-laparoscopic technique in dogs using Snook hook. The hypothesis is that non-laparoscopic minimally invasive ovariohysterectomy would be faster and less painful than the conventional technique. Thirty dogs were divided into Traditional Group (TG = 15) and Minimally Invasive Group (MIG = 15). Heart rate, respiratory rate, systolic blood pressure, body temperature, oxyhemoglobin saturation, end-tidal carbon dioxide concentration (ETCO2) and end-tidal isoflurane concentration were evaluated before the surgery begins (M0), during incision (M1), clamping of the first ovarian pedicle (M2), second ovarian pedicle (M3), uterine cervix (M4), abdominal suture (M5) and at the end of surgery (M6). The modified Glasgow Pain Scale was used for acute postoperative pain assessment and Visual Analogue Scale (VAS) was used to assess the sensitivity of surgical wound. The level of significance established for all statistical analysis was 5%. Statistical differences were not observed between groups considering total surgical time and postoperative acute pain intensity (P > 0.05), in spite of MIG having shorter duration of surgery. There was no statistical difference between groups considering all intraoperative parameters except respiratory rate (TG < MIG; P < 0.05) and ETCO2 (MIG < TG; P < 0.05) at the moment of traction of the first ovarian pedicle (M2). Pain assessment by VAS showed statistical difference 24h after the end of surgery (TG < MIG) (P < 0.05). Both procedures were similar regarding intraoperative nociception and acute postoperative pain. It is possible that the sensation of pain in both procedures was blocked by the effectiveness of analgesics, once they might cause an inhibition of painful behaviors limiting a possible difference in pain identification. Higher respiratory stress observed in MIG at M2 and higher pain score by VAS noted in MIG 24 h after the end of surgery can be justified by greater traction of ovarian pedicle, due to limited surgical access of minimally invasive technique. Minimally invasive ovariohysterectomy non-laparoscopic seems to be potentially faster, probably due to the smaller size of the abdominal incision, which takes less time to be closed. In the present study, both techniques were performed by an experienced surgeon, providing safe procedures, nevertheless it is important to emphasize that iatrogenic injury can be caused by surgeons non-proficient in the Snook hook technique, considering the limited visualization of anatomical abdominal structures. Data obtained indicate that traditional ovariohysterectomy and non-laparoscopic Snook hook technique promote similar intraoperative nociception and acute postoperative pain, however minimally invasive procedure is potentially faster with less surgical trauma.(AU)

Ablação total do conduto auditivo em cão com otite crônica / Total ablation of hearing conduct in dog with chronic otite

A otite é uma inflamação do canal auditivo que pode acometer o ouvido externo e médio, sendo sua patogenia dividida em fatores perpetuadores, predisponentes e primários. Os sinais clínicos mais comuns são eritema, dor a palpação, prurido e exsudação. Além do hitórico e anamnese, radiografia, otoscopia e biopsia podem auxiliar no diagnóstico. O tratamento inicial tem o objetivo de controlar os fatores perpetuadores, eliminar os fatores predisponentes e fazer o controle da causa base. Nos casos de otite externa crônica recidivante, estenose do canal auditivo, deformidades auriculares, pólipos e neoplasias, indica-se fazer o tratamento cirúrgico. O presente trabalho relata o caso de um canino sem raça definida, com treze anos de idade, atendido no Hospital Veterinário da Universidade Federal Rural do Semi-árido (UFERSA), apresentando odor fétido no pavilhão auricular, excesso de cerúmen de coloração escura, eritema, prurido e dor aguda a palpar-se a base do pavilhão auricular esquerdo. Através da anamnese, exame físico e dos exames complementares como a radiografia, o animal foi diagnosticado com otite crônica. Optouse, então, pelo tratamento cirúrgico de ablação total do conduto auditivo (TECA), que consiste na retirada do canal vertical e horizontal do ouvido, associado à osteotomia lateral da bula timpânica. O procedimento cirúrgico foi eficaz no tratamento da otite crônica não responsiva ao tratamento medicamentoso realizado previamente nos últimos cinco anos feito de forma intermitente pelo tutor.

Otitis is an inflammation of the ear canal that can affect the outer and middle ear, and its pathogenesis is divided into perpetuating, predisposing and primary factors. The most common clinical signs are erythema, pain on palpation, itching and oozing. In addition to the history and anamnesis, radiography, otoscopy and biopsy can assist in the diagnosis. The initial treatment aims to control the perpetuating factors, eliminate predisposing factors and control the underlying cause. In cases of recurrent chronic external otitis, stenosis of the ear canal, ear deformities, polyps and neoplasms, surgical treatment is indicated. The present work reports the case of a 13-year-old mixed breed canine, attended at the Veterinary Hospital of the Federal Rural University of the Semi-arid (UFERSA), with a foul odor in the ear, excess of dark colored cerumen, erythema, itching and acute pain palpating the base of the left ear. Through anamnesis, physical examination and complementary tests such as radiography, the animal was diagnosed with chronic otitis. Then, we opted for the surgical treatment of total ablation of the auditory canal (TECA), which consists of the removal of the vertical and horizontal ear canal, associated with lateral osteotomy of the tympanic bulla. The surgical procedure was effective in the treatment of chronic otitis unresponsive to drug treatment previously performed in the last five years, done intermittently by the tutor.

Ablação total do conduto auditivo em cão com otite crônica / Total ablation of hearing conduct in dog with chronic otite

A otite é uma inflamação do canal auditivo que pode acometer o ouvido externo e médio, sendo sua patogenia dividida em fatores perpetuadores, predisponentes e primários. Os sinais clínicos mais comuns são eritema, dor a palpação, prurido e exsudação. Além do hitórico e anamnese, radiografia, otoscopia e biopsia podem auxiliar no diagnóstico. O tratamento inicial tem o objetivo de controlar os fatores perpetuadores, eliminar os fatores predisponentes e fazer o controle da causa base. Nos casos de otite externa crônica recidivante, estenose do canal auditivo, deformidades auriculares, pólipos e neoplasias, indica-se fazer o tratamento cirúrgico. O presente trabalho relata o caso de um canino sem raça definida, com treze anos de idade, atendido no Hospital Veterinário da Universidade Federal Rural do Semi-árido (UFERSA), apresentando odor fétido no pavilhão auricular, excesso de cerúmen de coloração escura, eritema, prurido e dor aguda a palpar-se a base do pavilhão auricular esquerdo. Através da anamnese, exame físico e dos exames complementares como a radiografia, o animal foi diagnosticado com otite crônica. Optouse, então, pelo tratamento cirúrgico de ablação total do conduto auditivo (TECA), que consiste na retirada do canal vertical e horizontal do ouvido, associado à osteotomia lateral da bula timpânica. O procedimento cirúrgico foi eficaz no tratamento da otite crônica não responsiva ao tratamento medicamentoso realizado previamente nos últimos cinco anos feito de forma intermitente pelo tutor.(AU)

Otitis is an inflammation of the ear canal that can affect the outer and middle ear, and its pathogenesis is divided into perpetuating, predisposing and primary factors. The most common clinical signs are erythema, pain on palpation, itching and oozing. In addition to the history and anamnesis, radiography, otoscopy and biopsy can assist in the diagnosis. The initial treatment aims to control the perpetuating factors, eliminate predisposing factors and control the underlying cause. In cases of recurrent chronic external otitis, stenosis of the ear canal, ear deformities, polyps and neoplasms, surgical treatment is indicated. The present work reports the case of a 13-year-old mixed breed canine, attended at the Veterinary Hospital of the Federal Rural University of the Semi-arid (UFERSA), with a foul odor in the ear, excess of dark colored cerumen, erythema, itching and acute pain palpating the base of the left ear. Through anamnesis, physical examination and complementary tests such as radiography, the animal was diagnosed with chronic otitis. Then, we opted for the surgical treatment of total ablation of the auditory canal (TECA), which consists of the removal of the vertical and horizontal ear canal, associated with lateral osteotomy of the tympanic bulla. The surgical procedure was effective in the treatment of chronic otitis unresponsive to drug treatment previously performed in the last five years, done intermittently by the tutor.(AU)

Partial tear of the long digital extensor tendon in a dog / Ruptura parcial do tendão extensor digital longo em cão

The aim of this paper was to describe the clinical and sonographic findings of partial tear at the musculotendinous junction of the proximal long digital extensor tendon during the acute phase and one year after initial presentation. The dog presented with acute, moderate weight-bearing lameness of the right hind limb. During an orthopedic examination of the stifle, the dog expressed pain on extension and flexion of the right knee. Under general anesthesia, no instability was evident. Radiographic images suggested the presence of joint effusion in the right stifle. Ultrasonography revealed that the long digital extensor tendon was hyperechoic, surrounded by an anechoic effusion, and the muscle fibers were disorganized and interspersed with anechoic fluid. Clinical outcome was considered good after conservative treatment. The dog was re-evaluated approximately one year after treatment and did not present with any clinical signs.(AU)

O objetivo deste trabalho é descrever os achados clínicos e ultrassonográficos da ruptura parcial do tendão extensor digital longo em sua porção proximal, na junção musculotendínea, durante a fase aguda e um ano após a apresentação inicial. O cão apresentava claudicação aguda e moderada do membro posterior direito. Durante o exame ortopédico, o animal expressou dor na extensão e flexão do joelho direito. Sob anestesia geral, nenhuma instabilidade foi evidente. Imagens radiográficas sugeriram a presença de efusão articular na articulação do joelho direito. A ultrassonografia revelou que o tendão extensor digital longo estava hiperecóico, circundado por efusão anecóica, e as fibras musculares estavam desorganizadas e entremeadas por líquido anecóico. Após o tratamento conservador, a evolução clínica foi considerada satisfatória. O animal foi reavaliado aproximadamente um ano após o tratamento e não apresentou quaisquer sinais clínicos evidentes.(AU)

Avaliação da analgesia pós-operatória da dexmedetomidina isolada e associada à morfina quando utilizada na medicação pré-anestésica em cadelas submetidas à ovariosalpingohisterectomia eletiva / Evaluation of postoperative analgesia of dexmedetomidine alone or associated to morphine as premedicants in bitches undergoing ovariosalpingohisterectomy

Background: Elective ovariossalpingohysterectomy is a common surgery that causes mild to moderate pain. Aiming at the treatment of pain in these patients, analgesia should be balanced from pre-anesthetic, transoperative and postoperative medication, with-2-agonists and opioids being commonly used, especially dexmedetomidine that has sedation, relaxation muscle and analgesia.The aim of the present study was to evaluate the postoperative analgesic efficacy of dexmedetomidine alone and associated withmorphine when used in the preanesthetic medication of bitches submitted to elective ovarian oysterectomy using the modifiedGlasgow pain scale and the Melbourne pain scale.Materials, Methods & Results: Twenty bitches were used in this study, all of them submitted to ovarian oysterectomy, and were clinically healthy according to laboratory and clinical exams. During the experiment, bitches were randomly distributed into two groups,which received preanesthetic medication (MPA) with 5 μg/kg dexmedetomidine alone (GD) or associated with 0.3 mg/kg morphine(GDM) intramuscularly (IM). In both groups, anesthetic induction with dose-effect propofol was performed and maintained withisoflurane diluted in 100% oxygen administered through a calibrated vaporizer and appropriate anesthetic system based on the weightof the animal and maintained on spontaneous ventilation. After stabilization of the patient the surgery was started, which lasted 45min. The bitches were evaluated by the Modified Glasgow Scale (GSM), the Melbourne Scale (MS) and the Dobbins Sedation Scale(DS), previously administered MPA (T0) and the others performed in 1h (T1), 2h (T2), 4h (T3), 8h (T4), 12h (T5) and 24h (T6) afterextubation. If the GSM score was greater than the value of 3.3 an analgesic rescue of 0.5 mg/kg of morphine intramuscularly would beadministered. An increase in the scoring of pain scales in both groups can be observed from the T1, with significant difference only ofthe...(AU)

Avaliação da analgesia pós-operatória da dexmedetomidina isolada e associada à morfina quando utilizada na medicação pré-anestésica em cadelas submetidas à ovariosalpingohisterectomia eletiva / Evaluation of postoperative analgesia of dexmedetomidine alone or associated to morphine as premedicants in bitches undergoing ovariosalpingohisterectomy

Background: Elective ovariossalpingohysterectomy is a common surgery that causes mild to moderate pain. Aiming at the treatment of pain in these patients, analgesia should be balanced from pre-anesthetic, transoperative and postoperative medication, with-2-agonists and opioids being commonly used, especially dexmedetomidine that has sedation, relaxation muscle and analgesia.The aim of the present study was to evaluate the postoperative analgesic efficacy of dexmedetomidine alone and associated withmorphine when used in the preanesthetic medication of bitches submitted to elective ovarian oysterectomy using the modifiedGlasgow pain scale and the Melbourne pain scale.Materials, Methods & Results: Twenty bitches were used in this study, all of them submitted to ovarian oysterectomy, and were clinically healthy according to laboratory and clinical exams. During the experiment, bitches were randomly distributed into two groups,which received preanesthetic medication (MPA) with 5 μg/kg dexmedetomidine alone (GD) or associated with 0.3 mg/kg morphine(GDM) intramuscularly (IM). In both groups, anesthetic induction with dose-effect propofol was performed and maintained withisoflurane diluted in 100% oxygen administered through a calibrated vaporizer and appropriate anesthetic system based on the weightof the animal and maintained on spontaneous ventilation. After stabilization of the patient the surgery was started, which lasted 45min. The bitches were evaluated by the Modified Glasgow Scale (GSM), the Melbourne Scale (MS) and the Dobbins Sedation Scale(DS), previously administered MPA (T0) and the others performed in 1h (T1), 2h (T2), 4h (T3), 8h (T4), 12h (T5) and 24h (T6) afterextubation. If the GSM score was greater than the value of 3.3 an analgesic rescue of 0.5 mg/kg of morphine intramuscularly would beadministered. An increase in the scoring of pain scales in both groups can be observed from the T1, with significant difference only ofthe...

Avaliação pós-cirúrgica do impacto analgésico do tramadol epidural, quando associado à levobupivacaína, em cadelas submetidas à mastectomia e à ovariohisterectomia / Post-surgical evaluation of the analgesic impact of epidural tramadol, when associated with levobupivacaine, in bitches undergoing mastectomy and ovariohysterectomy

Background: Mammary tumors are the most common neoplasms in female dogs. Surgical removal of the mammary glandchain is considered the standard treatment and is usually performed along with ovariohysterectomy (OH) to suppressovarian hormonal influence. Mastectomies cause moderate to severe pain and require preferential multimodal analgesicprotocols. The aim of this study was to compare the postoperative analgesic efficacy and the recovery times on femaledogs undergoing mastectomies and OH between those treated with epidural levobupivacaine alone and those treated withassociated doses of tramadol and anesthetized with propofol.Materials, Methods & Results: Eighteen female dogs were pretreated with acepromazine (0.03 mg/kg), using propofol(4 mg/kg) for induction and anesthesia maintenance. The dogs were randomly divided into three groups (n = 6) treatedwith epidural anesthesia with levobupivacaine alone at 1.5 mg/kg (GL) or associated with tramadol at doses of 2 mg/kg(GLT2) or 4 mg/kg (GLT4). After anesthesia, the mean propofol infusion rate for each group were calculed. During thepostoperative period, the degree of analgesia according to the University of Melbourne Pain Scale for 6 hours were determined, considering seven time points for evaluation (M30, M60, M90, M120, M180, M240, and M360). Supplementalanalgesia with morphine (0.5 mg/kg) to those dogs with scores ≥13 were provided. During the recovery period, the timeintervals between the end of anesthesia, and the following events: extubation (EX), the first head movement (MC), and theestablishment of sternal (PE) and quadrupedal (PQ) positions were measured. Data were subjected to the Friedman testfor analysis of non-parametric variables within the same group and to the Mann–Whitney test for independent variables,comparing the mean scores between groups (statistical significance was set at P < 0.05). In the GL group, a higher meanpropofol infusion rate than in either the ...

Avaliação pós-cirúrgica do impacto analgésico do tramadol epidural, quando associado à levobupivacaína, em cadelas submetidas à mastectomia e à ovariohisterectomia / Post-surgical evaluation of the analgesic impact of epidural tramadol, when associated with levobupivacaine, in bitches undergoing mastectomy and ovariohysterectomy

Background: Mammary tumors are the most common neoplasms in female dogs. Surgical removal of the mammary glandchain is considered the standard treatment and is usually performed along with ovariohysterectomy (OH) to suppressovarian hormonal influence. Mastectomies cause moderate to severe pain and require preferential multimodal analgesicprotocols. The aim of this study was to compare the postoperative analgesic efficacy and the recovery times on femaledogs undergoing mastectomies and OH between those treated with epidural levobupivacaine alone and those treated withassociated doses of tramadol and anesthetized with propofol.Materials, Methods & Results: Eighteen female dogs were pretreated with acepromazine (0.03 mg/kg), using propofol(4 mg/kg) for induction and anesthesia maintenance. The dogs were randomly divided into three groups (n = 6) treatedwith epidural anesthesia with levobupivacaine alone at 1.5 mg/kg (GL) or associated with tramadol at doses of 2 mg/kg(GLT2) or 4 mg/kg (GLT4). After anesthesia, the mean propofol infusion rate for each group were calculed. During thepostoperative period, the degree of analgesia according to the University of Melbourne Pain Scale for 6 hours were determined, considering seven time points for evaluation (M30, M60, M90, M120, M180, M240, and M360). Supplementalanalgesia with morphine (0.5 mg/kg) to those dogs with scores ≥13 were provided. During the recovery period, the timeintervals between the end of anesthesia, and the following events: extubation (EX), the first head movement (MC), and theestablishment of sternal (PE) and quadrupedal (PQ) positions were measured. Data were subjected to the Friedman testfor analysis of non-parametric variables within the same group and to the Mann–Whitney test for independent variables,comparing the mean scores between groups (statistical significance was set at P < 0.05). In the GL group, a higher meanpropofol infusion rate than in either the ...(AU)