Some biochemical indices related to
diabetic complications were assessed in 86 diabetics and results compared with 20 normal controls.
Cholesterol, beta-lipoprotein, and
plasma fibrinogen levels were significantly higher in with vascular
complications when compared with normal controls.
Triglycerides were elevated in all groups, bi in
patients with retinopathy and venous
dilation. There was a
suggestion that
triglycerides were related in
dietary carbohydrate in maturity onset diabetics. It appears therefore that elevation of
lipids is correlated with the features of
diabetic vascular disease. Elevation of
lipids secondary to nephropathy establishes a vicious cycle in the
course of the
disease. Higher levels of
lipids can also explain the increased
platelet adhesiveness and aggregation