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Hepatitis B virus infection and vaccine-induced immunity in Madrid (Spain) / Infección por el virus de la hepatitis B e inmunidad inducida por la vacuna en Madrid (España)

Pedraza-Flechas, Ana María; García-Comas, Luis; Ordobás-Gavín, María; Sanz-Moreno, Juan Carlos; Ramos-Blázquez, Belén; Astray-Mochales, Jenaro; Moreno-Guillén, Santiago.
Gac. sanit. (Barc., Ed. impr.) ; 28(6): 492-495, nov.-dic. 2014. tab, ilus
Artículo en Inglés | IBECS (España) | ID: ibc-130409
Objective. To estimate the prevalence of hepatitis B virus (HBV) infection and vaccine-induced immunity in the region of Madrid, and to analyze their evolution over time. Methods. An observational, analytical, cross-sectional study was carried out in the population aged 16-80 years between 2008 and 2009. This was the last of four seroprevalence surveys in the region of Madrid. The prevalence of HBV infection and vaccine-induced immunity was estimated using multivariate logistic models and were compared with the prevalences in the 1989, 1993 and 1999 surveys. Results. In the population aged 16-80 years, the prevalence of HBV infection was 11.0% (95% CI 9.8-12.3) and that of chronic infection was 0.7% (95% CI 0.5-1.1). The prevalence of vaccine-induced immunity in the population aged 16-20 years was 73.0% (95% CI 70.0-76.0). Compared with previous surveys, there was a decrease in the prevalence of HBV infection. Conclusions. Based on the prevalence of chronic infection (< 1 %), Madrid is a region with low HBV endemicity. Preventive strategies against HBV should especially target the immigrant population (AU)
Biblioteca responsable: ES1.1
Ubicación: BNCS