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Instituto Evandro Chagas

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Complete Nucleotide Sequences of Two blaKPC-2-Bearing IncN Plasmids Isolated from Sequence Type 442 Klebsiella pneumoniae Clinical Strains Four Years Apart

Pérez-Chaparro, Paula Juliana; Cerdeira, Louise Teixeira; Queiroz, Maíse Gomes; Lima, Clayton Pereira Silva de; Levy, Carlos Emílio; Pavez, Mónica; Lincopan, Nilton; Gonçalves, Evonnildo Costa; Mamizuka, Elsa Masae; Sampaio, Jorge Luiz Mello; Nunes, Márcio Roberto Teixeira; McCulloch, John Anthony.
Antimicrob Agents Chemother ; 58(5): 2958 - 2960, June 2, 2014. ilus
Artigo em Inglês | Instituto Evandro Chagas (SOPHIA) | ID: iec-14291
We sequenced the oldest blaKPC-2-bearing plasmid isolated in Brazil and another plasmid also carried by a Klebsiella pneumoniae strain of sequence type 442 (ST442), isolated 52 months later. Both plasmids present an IncN backbone and few acquired regions. Because the 2005 plasmid presented deletions and a truncated gene within Tn4401b compared to the 2009 plasmid, we can thus infer that IncN blaKPC-2-bearing plasmids pFCF1305 and pFCF3SP had a common ancestor circulating in Brazil prior toMay 2005. (AU)
Biblioteca responsável: BR275.1
Localização: PCIEC2014 / BR275.1