Opsoclonus-
myoclonus-
ataxia syndrome (OMAS) is a rare
neurological disorder characterized by irregular multidirectional
eye movements,
myoclonus,
cerebellar ataxia,
sleep disturbances, and
cognitive dysfunction. Although most commonly related to
paraneoplastic syndrome, this condition has occasionally been described following infectious illnesses. This article
reports the first case of OMAS in
association with chikungunya and
dengue virus co-infection. The genetic
analysis identified
chikungunya virus of East/Central/South African
genotype and
dengue serotype 4
virus of
genotype II. This
report represents an unusual clinical
syndrome associated with viral
co-infection and reinforces the need for clinical vigilance with regard to neurological
syndromes in the context of emergent
arboviruses.