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Human T lymphotropic virus and pulmonary diseases

Dias, Apio R. N; Falcão, Luiz F. M; Falcão, Aline S. C; Normando, Valéria M. F; Quaresma, Juarez A. S.
Front Microbiol; 9(1879): 1-7, 2018. ilus.
Artigo em Inglês | IEC - Instituto Evandro Chagas | ID: iec-17543
Human T lymphotropic virus type 1 (HTLV-1) is the etiological agent of HTLV-1-associated myelopathy, and adult T cell lymphoma/leukemia (ATL/L). Pulmonary complications such as alveolitis and bronchiectasis were found in individuals who develop TSP/HAM due to chronic inflammation. These individuals showed image anomalies in CT scans and changes in pulmonary function parameters distinctive of pulmonary disease. Furthermore, infected individuals have a greater susceptibility to pulmonary tuberculosis either due to changes in the innate immune response, in asymptomatic carriers, or to an opportunistic disease linked to immunodepression, in individuals who develop ATL/L. This summary addresses the general lack of knowledge regarding the relationship between HTLV-1 and pulmonary diseases and provides direction for future work.
Biblioteca responsável: BR275.1
Localização: PCIEC2018 / BR275.1