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Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk.
Galarza-Muñoz, Gaddiel; Briggs, Farren B S; Evsyukova, Irina; Schott-Lerner, Geraldine; Kennedy, Edward M; Nyanhete, Tinashe; Wang, Liuyang; Bergamaschi, Laura; Widen, Steven G; Tomaras, Georgia D; Ko, Dennis C; Bradrick, Shelton S; Barcellos, Lisa F; Gregory, Simon G; Garcia-Blanco, Mariano A.
Afiliação
  • Galarza-Muñoz G; Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA; Center for RNA Biology, Duke University, Durham, NC 27710, USA; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
  • Briggs FBS; Department of Epidemiology and Biostatistics, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
  • Evsyukova I; Center for RNA Biology, Duke University, Durham, NC 27710, USA.
  • Schott-Lerner G; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
  • Kennedy EM; Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.
  • Nyanhete T; Department of Immunology, Duke University Durham, NC 27710, USA; Department of Surgery, Duke University Durham, NC 27710, USA.
  • Wang L; Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.
  • Bergamaschi L; Duke Molecular Physiology Institute, Duke University, Durham, NC 27701, USA.
  • Widen SG; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
  • Tomaras GD; Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA; Department of Immunology, Duke University Durham, NC 27710, USA; Department of Surgery, Duke University Durham, NC 27710, USA.
  • Ko DC; Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA; Department of Medicine, Duke University Medical Center; Durham, NC 27710, USA.
  • Bradrick SS; Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA; Center for RNA Biology, Duke University, Durham, NC 27710, USA; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
  • Barcellos LF; Division of Epidemiology, School of Public Health, University of California Berkeley, Berkeley, CA 94720, USA.
  • Gregory SG; Duke Molecular Physiology Institute, Duke University, Durham, NC 27701, USA; Department of Neurology, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: simon.gregory@duke.edu.
  • Garcia-Blanco MA; Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA; Center for RNA Biology, Duke University, Durham, NC 27710, USA; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA. Electronic address
Cell ; 169(1): 72-84.e13, 2017 03 23.
Article em En | MEDLINE | ID: mdl-28340352
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Splicing de RNA / Epistasia Genética / RNA Helicases DEAD-box / Subunidade alfa de Receptor de Interleucina-7 Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Splicing de RNA / Epistasia Genética / RNA Helicases DEAD-box / Subunidade alfa de Receptor de Interleucina-7 Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos