Intoxicación letal suicida con cloroquina / Suicide due to chloroquine poisoning

RESUMEN

Es poco habitual encontrar casos de intoxicación por sobredosis aguda de cloroquina de etiología suicida. Realizamos un análisis de 2 casos de muerte por cloroquina sujetos a autopsia médico-legal, ambos ocurridos en Barcelona entre enero de 2010 y julio de 2011. De la totalidad de análisis toxicológicos necrópsicos efectuados en Barcelona durante los 19 meses se atribuye un 0,16% a la mortalidad por cloroquina. El levantamiento de cadáver es la clave para poder iniciar la búsqueda toxicológica específica y obtener el diagnóstico. Nuestro estudio y la revisión bibliográfica confirman que en las intoxicaciones letales por cloroquina los hallazgos morfológicos, como en otras intoxicaciones, son inespecíficos(AU)

ABSTRACT

It is not very common to find cases of suicide due to acute poisoning by an overdose of chloroquine. An analysis was made of two cases of death caused by chloroquine subjected to a medical-legal autopsy, both of which took place in Barcelona during the years 2010 and 2011. The frequency of poisoning attributed to chloroquine in the city of Barcelona during the 19 months between January 2010 and July 2011 was established as 0.16% of the mortality by the Forensic Pathology Department (SPF) of the Catalonian Institute of Legal Medicine (IMLC). The examination of the scene of death is the key point to be able to initiate the specific toxicological search to obtain the diagnosis. Our study and the literature review confirmed that in lethal poisonings due to chloroquine, as in other poisonings, the morphological findings are non-specific(AU)