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The Impact of the Nurses' Health Study on Population Health: Prevention, Translation, and Control.

Colditz, Graham A; Philpott, Sydney E; Hankinson, Susan E.
Am J Public Health; 106(9): 1540-5, 2016 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-27459441

OBJECTIVES:

To summarize the overall impact of the Nurses' Health Study (NHS) over the past 40 years on the health of populations through its contributions on prevention, translation, and control.

METHODS:

We performed a narrative review of the findings of the NHS, NHS II, and NHS3 between 1976 and 2016.

RESULTS:

The NHS has generated significant findings about the associations between (1) smoking and type 2 diabetes, cardiovascular diseases, colorectal and pancreatic cancer, psoriasis, multiple sclerosis, and eye diseases; (2) physical activity and cardiovascular diseases, breast cancer, psoriasis, and neurodegeneration; (3) obesity and cardiovascular diseases, numerous cancer sites, psoriasis, multiple sclerosis, kidney stones, and eye diseases; (4) oral contraceptives and cardiovascular disease, melanoma, and breast, colorectal, and ovarian cancer; (5) hormone therapy and cardiovascular diseases, breast and endometrial cancer, and neurodegeneration; (6) endogenous hormones and breast cancer; (7) dietary factors and type 2 diabetes, cardiovascular diseases, breast and pancreatic cancer, non-Hodgkin's lymphoma, neurodegeneration, multiple sclerosis, kidney stones, and eye diseases; and (8) sleep and shift work and chronic diseases.

CONCLUSIONS:

The NHS findings have influenced public health policy and practice both locally and globally to improve women's health.