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Resultados  1-12 de 24
1.

Update: Influenza Activity - United States, October 2-December 17, 2016.

Autor(es): Shang, Mei; Blanton, Lenee; Kniss, Krista; Mustaquim, Desiree; Alabi, Noreen; Barnes, Stephen; Budd, Alicia; Davlin, Stacy L; Kramer, Natalie; Garg, Shikha; Cummings, Charisse N; Flannery, Brendan; Fry, Alicia M; Grohskopf, Lisa A; Olsen, Sonja J; Bresee, Joseph; Sessions, Wendy; Garten, Rebecca; Xu, Xiyan; Elal, Anwar Isa Abd; Gubareva, Larisa; Barnes, John; Wentworth, David E; Burns, Erin; Katz, Jacqueline; Jernigan, Daniel; Brammer, Lynnette
Fonte: MMWR Morb Mortal Wkly Rep;65(5051): 1439-1444, 2016 Dec 30.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 28033315
Resumo: This report summarizes U.S. influenza activity during October 2-December 17, 2016. Influenza activity in the United States remained low in October and has been slowly increasing since November. Influenza A viruses were identified most frequently, with influenza A (H3N2) viruses predominating. Most influenza viruses characterized during this period were genetically or antigenically similar to the reference viruses representing vaccine components recommended for production in the 2016-17 Northern Hemisphere influenza vaccines.
2.

Seasonal Influenza A H1N1pdm09 Virus and Severe Outcomes: A Reason for Broader Vaccination in Non-Elderly, At-Risk People.

Autor(es): Minchole, Elisa; Figueredo, Ana L; Omeñaca, Manuel; Panadero, Carolina; Royo, Laura; Vengoechea, Jose J; Fandos, Sergio; de Pablo, Francisco; Bello, Salvador
Fonte: PLoS One;11(11): e0165711, 2016.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27832114
Resumo: BACKGROUND: Recent pandemics of influenza A H1N1pdm09 virus have caused severe illness, especially in young people. Very few studies on influenza A H1N1pdm09 in post-pandemic periods exist, and there is no information on the severity of both seasonal influenza A(H1N1) and A(H3N2) from the same season, adjusting for potential confounders, including vaccine. METHODS AND RESULTS: We performed a retrospective observational study of adults hospitalized during the 2014 season with influenza A(H1N (mais)
3.

A De- -acylated Lipooligosaccharide-Based Adjuvant System Promotes Antibody and Th1-Type Immune Responses to H1N1 Pandemic Influenza Vaccine in Mice.

Autor(es): Ryu, Ji In; Park, Shin Ae; Wui, Seo Ri; Ko, Ara; Han, Ji Eun; Choi, Jung Ah; Song, Man Ki; Kim, Kwang Sung; Cho, Yang Je; Lee, Na Gyong
Fonte: Biomed Res Int;2016: 3713656, 2016.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27891512
Resumo: Vaccine adjuvants are agents that are used to promote immune responses to vaccine antigens and thereby to enhance the protective efficacy of the vaccines. In this study, we investigated the adjuvant activity of CIA06, an adjuvant system that is composed of a toll-like receptor 4 agonist de- -acylated lipooligosaccharide (dLOS) and aluminum hydroxide, on the H1N1 pandemic influenza vaccine Greenflu-S® in mice. CIA06 significantly enhanced influenza-specific serum IgG, hemagglutination-inhib (mais)
5.

Encefalopatía no fatal por influenza AH1N1 en paciente pediátrico/ Non-fatal case of H1n1 influenza encephalopathy in a pediatric patient

Autor(es): Valdivia-Tapia, María del Carmen; Carreazo, Nilton Yhuri
Fonte: Rev Peru Med Exp Salud Publica;33(3): 585-587, jul.-sep. 2016. graf
LILACS - Literatura Latino-Americana e do Caribe em Ciências da Saúde ID: 798227  LILACS Express
Resumo: RESUMEN Niña de dos años con fiebre y síntomas catarrales que presenta convulsiones focales de hemicuerpo derecho, las cuales persisten adicionándose signos de hipertensión endocraneana. Se identifica Influenza AH1N1 mediante reacción de cadena de polimerasa en hisopado nasofaríngeo. Paciente evoluciona favorablemente con medidas de soporte. No recibió Oseltamivir.
ABSTRACT A 2-year-old girl presented with fever, catarrhal symptoms, and focal right hemispheric seizures that per (mais)
6.

Infant Respiratory Outcomes Associated with Prenatal Exposure to Maternal 2009 A/H1N1 Influenza Vaccination.

Autor(es): Fell, Deshayne B; Wilson, Kumanan; Ducharme, Robin; Hawken, Steven; Sprague, Ann E; Kwong, Jeffrey C; Smith, Graeme; Wen, Shi Wu; Walker, Mark C
Fonte: PLoS One;11(8): e0160342, 2016.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27486858
Resumo: BACKGROUND: Infants are at high risk for influenza illness, but are ineligible for vaccination before 6 months. Transfer of maternal antibodies to the fetus has been demonstrated for 2009 A/H1N1 pandemic vaccines; however, clinical effectiveness is unknown. Our objective was to evaluate the association between 2009 A/H1N1 pandemic vaccination during pregnancy and rates of infant influenza and pneumonia. METHODS: We linked a population-based birth cohort to administrative databases to measur (mais)
7.

Combination of ribavirin and reduning protects mice against severe pneumonia induced by H1N1 influenza a virus.

Autor(es): Ma, Yuexia; Zhang, Wei; Zhao, Zhongpeng; Li, Min; Liu, Jian; Wang, Yuguang
Fonte: J Tradit Chin Med;36(2): 181-6, 2016 Apr.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27400472
Resumo: OBJECTIVE: To investigate the effects of ribavirin administration combined with Reduning in a mouse model of influenza A (H1N1)-induced severe pneumonia. METHODS: Influenza A/Beijing/501/2009 (H1N1)-infected C57BL/6 mice were randomly divided into four experimental groups treated with either a mock injection of phosphate-buffered saline (PBS), ribavirin (66.6 mg/kg daily) or Reduning (86.6 mg/ kg daily), or a combination of both, for 7 days. Mice were monitored for clinical signs and surviv (mais)
8.

Influenza Activity - United States, 2015-16 Season and Composition of the 2016-17 Influenza Vaccine.

Autor(es): Davlin, Stacy L; Blanton, Lenee; Kniss, Krista; Mustaquim, Desiree; Smith, Sophie; Kramer, Natalie; Cohen, Jessica; Cummings, Charisse Nitura; Garg, Shikha; Flannery, Brendan; Fry, Alicia M; Grohskopf, Lisa A; Bresee, Joseph; Wallis, Teresa; Sessions, Wendy; Garten, Rebecca; Xu, Xiyan; Elal, Anwar Isa Abd; Gubareva, Larisa; Barnes, John; Wentworth, David E; Burns, Erin; Katz, Jacqueline; Jernigan, Daniel; Brammer, Lynnette
Fonte: MMWR Morb Mortal Wkly Rep;65(22): 567-75, 2016 Jun 10.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27281364
Resumo: During the 2015-16 influenza season (October 4, 2015-May 21, 2016) in the United States, influenza activity* was lower and peaked later compared with the previous three seasons (2012-13, 2013-14, and 2014-15). Activity remained low from October 2015 until late December 2015 and peaked in mid-March 2016. During the most recent 18 influenza seasons (including this season), only two other seasons have peaked in March (2011-12 and 2005-06). Overall influenza activity was moderate this season, w (mais)
9.

1, 8-Cineol Protect Against Influenza-Virus-Induced Pneumonia in Mice.

Autor(es): Li, Yun; Lai, Yanni; Wang, Yao; Liu, Ni; Zhang, Fengxue; Xu, Peiping
Fonte: Inflammation;39(4): 1582-93, 2016 Aug.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27351430
Resumo: 1,8-Cineol is a major monoterpene principally from eucalyptus essential oils and has been shown to exert anti-inflammatory, antiviral, and inhibitory of nuclear factor (NF)-kB effect. In the present study, we evaluated the effect of 1,8-cineol on mice infected with influenza A virus. We found that 1,8-cineol protects against influenza viral infection in mice. Moreover, 1,8-cineol efficiently decreased the level of IL-4, IL-5, IL-10, and MCP-1 in nasal lavage fluids and the level of IL-1ß, (mais)
10.

Influenza A and methicillin-resistant Staphylococcus aureus co-infection in rhesus macaques - A model of severe pneumonia.

Autor(es): Chertow, Daniel S; Kindrachuk, Jason; Sheng, Zong-Mei; Pujanauski, Lindsey M; Cooper, Kurt; Nogee, Daniel; Claire, Marisa St; Solomon, Jeffrey; Perry, Donna; Sayre, Philip; Janosko, Krisztina B; Lackemeyer, Matthew G; Bohannon, Jordan K; Kash, John C; Jahrling, Peter B; Taubenberger, Jeffery K
Fonte: Antiviral Res;129: 120-9, 2016 May.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 26923881
Resumo: BACKGROUND: Influenza results in up to 500,000 deaths annually. Seasonal influenza vaccines have an estimated 60% effectiveness, but provide little or no protection against novel subtypes, and may be less protective in high-risk groups. Neuraminidase inhibitors are recommended for the treatment of severe influenza infection, but are not proven to reduce mortality in severe disease. Preclinical models of severe influenza infection that closely correlate to human disease are needed to assess (mais)
11.

OX40 ligand newly expressed on bronchiolar progenitors mediates influenza infection and further exacerbates pneumonia.

Autor(es): Hirano, Taizou; Kikuchi, Toshiaki; Tode, Naoki; Santoso, Arif; Yamada, Mitsuhiro; Mitsuhashi, Yoshiya; Komatsu, Riyo; Kawabe, Takeshi; Tanimoto, Takeshi; Ishii, Naoto; Tanaka, Yuetsu; Nishimura, Hidekazu; Nukiwa, Toshihiro; Watanabe, Akira; Ichinose, Masakazu
Fonte: EMBO Mol Med;8(4): 422-36, 2016 Apr 01.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 26976612
Resumo: Influenza virus epidemics potentially cause pneumonia, which is responsible for much of the mortality due to the excessive immune responses. The role of costimulatory OX40-OX40 ligand (OX40L) interactions has been explored in the non-infectious pathology of influenza pneumonia. Here, we describe a critical contribution of OX40L to infectious pathology, with OX40L deficiency, but not OX40 deficiency, resulting in decreased susceptibility to influenza viral infection. Upon infection, bronchio (mais)
12.

Update: Influenza Activity--United States, October 4, 2015-February 6, 2016.

Autor(es): Russell, Kate; Blanton, Lenee; Kniss, Krista; Mustaquim, Desiree; Smith, Sophie; Cohen, Jessica; Garg, Shikha; Flannery, Brendan; Fry, Alicia M; Grohskopf, Lisa A; Bresee, Joseph; Wallis, Teresa; Sessions, Wendy; Garten, Rebecca; Xu, Xiyan; Elal, Anwar Isa Abd; Gubareva, Larisa; Barnes, John; Wentworth, David E; Burns, Erin; Katz, Jacqueline; Jernigan, Daniel; Brammer, Lynnette
Fonte: MMWR Morb Mortal Wkly Rep;65(6): 146-53, 2016 Feb 19.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 26891596
Resumo: From October through mid-December 2015, influenza activity remained low in most regions of the United States. Activity began to increase in late December 2015 and continued to increase slowly through early February 2016. Influenza A viruses have been most frequently identified, with influenza A (H3N2) viruses predominating during October until early December, and influenza A (H1N1)pdm09 viruses predominating from mid-December until early February. Most of the influenza viruses characterized (mais)
Resultados  1-12 de 24