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Pesquisa | Influenza A (H1N1)

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Resultados  1-12 de 97
1.

Community- and hospital-acquired infections with oseltamivir- and peramivir-resistant influenza A(H1N1)pdm09 viruses during the 2015-2016 season in Japan.

Autor(es): Hibino, Akinobu; Kondo, Hiroki; Masaki, Hironori; Tanabe, Yoshinari; Sato, Isamu; Takemae, Nobuhiro; Saito, Takehiko; Zaraket, Hassan; Saito, Reiko
Fonte: Virus Genes;53(1): 89-94, 2017 Feb.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27714496
Resumo: We report five cases of community- and hospital-acquired infections with oseltamivir- and peramivir-resistant A(H1N1)pdm09 viruses possessing the neuraminidase (NA) H275Y mutation during January-February 2016 in Japan. One case was hospitalized and was receiving oseltamivir for prophylaxis. The remaining four cases were not taking antiviral drugs at the time of sampling. These cases were geographically distant and epidemiologically unrelated. The five viruses showed ~300-fold rise in IC va (mais)
2.

Successful use of oseltamivir prophylaxis in managing a nosocomial outbreak of influenza A in a hematology and allogeneic stem cell transplant unit.

Autor(es): Yue, Mimi C; Collins, Joel T; Subramoniapillai, Elango; Kennedy, Glen A
Fonte: Asia Pac J Clin Oncol;13(1): 37-43, 2017 Feb.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27730741
Resumo: AIM: To describe a nosocomial outbreak of H1N1 influenza A in an inpatient hematology and allogeneic stem cell transplant unit and outcomes of universal oseltamivir prophylaxis. METHODS: Medical records of all patients admitted to the unit were reviewed to define the nosocomial outbreak, commencing 1 week prior to the index case until 4 weeks following institution of oseltamivir prophylaxis. Timelines for clinical symptoms, viral spread, management, patient outcomes and follow up testing we (mais)
3.

The pharmacological management of severe influenza infection - 'existing and emerging therapies'.

Autor(es): Mc Mahon, Aisling; Martin-Loeches, Ignacio
Fonte: Expert Rev Clin Pharmacol;10(1): 81-95, 2017 Jan.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27797595
Resumo: INTRODUCTION: Over the last century several influenza outbreaks have traversed the globe, most recently the influenza A(H1N1) 2009 pandemic. On each occasion, a highly contagious, virulent pathogen has emerged, leading to significant morbidity and mortality amongst those affected. Areas covered: Early antiviral therapy and supportive care is the mainstay of treatment. Treatment should be started as soon as possible and not delayed for the results of diagnostic testing. Whilst oseltamivir is (mais)
4.

Influenza virus infections in patients with malignancies -- characteristics and outcome of the season 2014/15. A survey conducted by the Infectious Diseases Working Party (AGIHO) of the German Society of Haematology and Medical Oncology (DGHO).

Autor(es): Hermann, B; Lehners, N; Brodhun, M; Boden, K; Hochhaus, A; Kochanek, M; Meckel, K; Mayer, K; Rachow, T; Rieger, C; Schalk, E; Weber, T; Schmeier-Jürchott, A; Schlattmann, P; Teschner, D; von Lilienfeld-Toal, M
Fonte: Eur J Clin Microbiol Infect Dis;36(3): 565-573, 2017 Mar.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27838792
Resumo: Influenza virus infections (IVI) may pose a vital threat to immunocompromised patients such as those suffering from malignancies, but specific data on epidemiology and outcome in these patients are scarce. In this study, we collected data on patients with active cancer or with a history of cancer, presenting with documented IVI in eight centres in Germany. Two hundred and three patients were identified, suffering from haematological malignancies or solid tumours; 109 (54 %) patients had ac (mais)
5.

Antiviral susceptibility profile of influenza A viruses; keep an eye on immunocompromised patients under prolonged treatment.

Autor(es): Kossyvakis, A; Mentis, A-F A; Tryfinopoulou, K; Pogka, V; Kalliaropoulos, A; Antalis, E; Lytras, T; Meijer, A; Tsiodras, S; Karakitsos, P; Mentis, A F
Fonte: Eur J Clin Microbiol Infect Dis;36(2): 361-371, 2017 Feb.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27848039
Resumo: There was an increase in severe and fatal influenza cases in Greece during the 2011-2015 post-pandemic period. To investigate causality, we determined neuraminidase (NA) inhibitor susceptibility and resistance-conferring NA and hemagglutinin (HA) mutations in circulating influenza type A viruses during the pandemic (2009-2010) and post-pandemic periods in Greece. One hundred thirty-four influenza A(H1N1)pdm09 and 95 influenza A(H3N2) viruses submitted to the National Influenza Reference Lab (mais)
6.

Contribution of a rapid influenza diagnostic test to manage hospitalized patients with suspected influenza.

Autor(es): Busson, Laurent; Mahadeb, Bhavna; De Foor, Marc; Vandenberg, Olivier; Hallin, Marie
Fonte: Diagn Microbiol Infect Dis;87(3): 238-242, 2017 Mar.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27939284
Resumo: AIM: To evaluate the performances of the Alere i influenza A&B test and to appraise its contribution to patient management. METHODS: In total, 267 samples were tested. Influenza A and B PCR was performed as the reference. For each positive result, the supervising physician was contacted to collect data regarding patient management. FINDINGS: The overall sensitivity and specificity of the Alere i were 91.4% and 97.6% for influenza A and 54.5% and 98.8% for influenza B, respectively. More spe (mais)
7.

The mechanisms of sudden-onset type adverse reactions to oseltamivir.

Autor(es): Hama, R; Bennett, C L
Fonte: Acta Neurol Scand;135(2): 148-160, 2017 Feb.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27364959
Resumo: Oseltamivir is contraindicated for people aged 10-19 in principle in Japan, due to concern about abnormal behaviours. Sudden death is another concern. This review examines growing evidence of their association and discusses underlying mechanisms of these sudden-onset type reactions to oseltamivir. First, the importance of animal models and the concept of human equivalent dose (HED) is summarized. Second, the specific condition for oseltamivir use, influenza infection, is reviewed. Third, fi (mais)
8.

Severe acute respiratory infection caused by swine influenza virus in a child necessitating extracorporeal membrane oxygenation (ECMO), the Netherlands, October 2016.

Autor(es): Fraaij, Pieter L A; Wildschut, Enno D; Houmes, Robert J; Swaan, Corien M; Hoebe, Christian J; de Jonge, H C C; Tolsma, Paulien; de Kleer, Isme; Pas, Suzan D; Oude Munnink, Bas B; Phan, My V T; Bestebroer, Theo M; Roosenhoff, R Shanty; van Kampen, Jeroen J A; Cotten, Matthew; Beerens, Nancy; Fouchier, Ron A M; van den Kerkhof, Johannes H; Timen, Aura; Koopmans, Marion P
Fonte: Euro Surveill;21(48)2016 Dec 01.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27934581
Resumo: In October 2016, a severe infection with swine influenza A(H1N1) virus of the Eurasian avian lineage occurred in a child with a previous history of eczema in the Netherlands, following contact to pigs. The patient's condition deteriorated rapidly and required life support through extracorporeal membrane oxygenation. After start of oseltamivir treatment and removal of mucus plugs, the patient fully recovered. Monitoring of more than 80 close unprotected contacts revealed no secondary cases.
10.

Factors associated with clinical outcome in 25 patients with avian influenza A (H7N9) infection in Guangzhou, China.

Autor(es): Wang, Hui; Xiao, XinCai; Lu, Jianyun; Chen, Zongqiu; Li, Kuibiao; Liu, Hui; Luo, Lei; Wang, Ming; Yang, ZhiCong
Fonte: BMC Infect Dis;16(1): 534, 2016 Oct 03.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27716101
Resumo: BACKGROUND: Guangzhou reported its first laboratory-confirmed case of influenza A (H7N9) on January 10, 2014. A total of 25 cases were reported from the first wave of the epidemic until April 8, 2014. The fatality rate was much higher than in previous reports. The objective of the current work was to describe the clinical and epidemiological characteristics of A (H7N9) patients in Guangzhou and explore possible reasons for the high fatality rate. METHODS: Clinical and epidemiological inform (mais)
11.

Oseltamivir as a cause of acute enterorrhagia.

Autor(es): Beraldi-Magalhães, Francisco; Batista, Vera; Cordeiro-Santos, Marcelo
Fonte: Braz J Infect Dis;20(5): 521, 2016 Sep-Oct.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27542865
12.

Unexpected platelets elevation in a patient with idiopathic thrombocytopenia treated with oseltamivir for influenza infection.

Autor(es): Bigot, Pierre; Auffret, Marine; Gautier, Sophie; Weinborn, Marie; Ettahar, Nicolas-Kader; Coupé, Patrick
Fonte: Fundam Clin Pharmacol;30(5): 483-5, 2016 Oct.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 27343486
Resumo: Oseltamivir is a neuraminidase inhibitor approved for the prevention and treatment of influenza. Few haematological side effects have been reported with oseltamivir. We report herein the case of an unexpected platelet increase in a 46-year-old woman with idiopathic thrombocytopenia (ITP) treated with oseltamivir for influenza. The mechanism may involve the neuraminidase inhibition which decrease platelet surface sialic acid content and reduce their removal by the reticuloendothelial system. (mais)
Resultados  1-12 de 97