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1.
Equine and canine influenza: a review of current events.
Fonte: Anim Health Res Rev;11(1): 43-51, 2010 Jun.
PMID: 20426896
Resumo:
In the past decade, the pandemics of highly pathogenic avian influenza H5N1 and the novel H1N1 influenza have both illustrated the potential of influenza viruses to rapidly emerge and spread widely in animals and people. Since both of these viruses are zoonotic, these pandemics have been the driving force behind a renewed commitment by the medical and veterinary professions to practice One World, One Health for the control of infectious diseases. The discovery in 2004 that an equine origin
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2.
Swine influenza vaccines: current status and future perspectives.
Fonte: Anim Health Res Rev;11(1): 81-96, 2010 Jun.
PMID: 20462470
Resumo:
Swine influenza is an important contagious disease in pigs caused by influenza A viruses. Although only three subtypes of influenza A viruses, H1N1, H1N2 and H3N2, predominantly infect pigs worldwide, it is still a big challenge for vaccine manufacturers to produce efficacious vaccines for the prevention and control of swine influenza. Swine influenza viruses not only cause significant economic losses for the swine industry, but are also important zoonotic pathogens. Vaccination is still on
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3.
Perspectives on influenza evolution and the role of research.
Fonte: Anim Health Res Rev;11(1): 3-18, 2010 Jun.
PMID: 20591210
Resumo:
Influenza is a highly contagious respiratory pathogen that continues to evolve and threaten both veterinary and human public health. Influenza A viruses are continually undergoing molecular changes through mutations, reassortment, and, in rare instances, recombination. While they generally cause benign enteric infection in their natural reservoir of wild aquatic birds, they can cause catastrophic and potentially lethal disease outbreaks in humans, domestic poultry, and pigs when they cross
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4.
A local health department's school-located vaccination clinics experience with H1N1 pandemic influenza vaccine.
Fonte: J Sch Health;80(7): 325, 2010 Jul.
PMID: 20591096
5.
Morbidity of pandemic H1N1 influenza in children with cancer.
Fonte: Pediatr Blood Cancer;55(2): 226-8, 2010 Aug.
PMID: 20582951
Resumo:
BACKGROUND: To define the mortality and the current impact of the H1N1 pandemic in pediatric hematology-oncology centers, we performed a specific survey. PROCEDURE: Pharyngeal swabs from patients with fevers of unknown origin, flu-like symptoms or bronchopneumonia were screened for H1N1 using PCR. RESULTS: Sixty-two patients with documented H1N1 infection were reported: 16 had recently stopped therapy, 2 were at the diagnosis stage, and 44 were receiving therapy. The clinical course was sev
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6.
Production of cell culture (MDCK) derived live attenuated influenza vaccine (LAIV) in a fully disposable platform process.
Fonte: Biotechnol Bioeng;106(6): 906-17, 2010 Aug 15.
PMID: 20589670
Resumo:
The majority of influenza vaccines are manufactured using embryonated hens' eggs. The potential occurrence of a pandemic outbreak of avian influenza might reduce or even eliminate the supply of eggs, leaving the human population at risk. Also, the egg-based production technology is intrinsically cumbersome and not easily scalable to provide a rapid worldwide supply of vaccine. In this communication, the production of a cell culture (Madin-Darby canine kidney (MDCK)) derived live attenuated
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7.
Effect of Clinical and Virological Parameters on the Level of Neutralizing Antibody against Pandemic Influenza A Virus H1N1 2009.
Fonte: Clin Infect Dis;51(3): 274-9, 2010 Aug 1.
PMID: 20575664
Resumo:
Background. Little is known about the antibody response in natural infection by the novel 2009 influenza A (H1N1) virus and its relationship with clinical and virological parameters. The relative lack of background neutralizing antibody against this novel virus provides a unique opportunity for understanding this issue. Methods. Case patients presenting with influenza-like illness who were positive for the pandemic H1 gene by reverse transcription polymerase chain reaction were identified.
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8.
Factors Associated with Health Care-Associated 2009 Influenza A (H1N1) Virus Infection among Thai Health Care Workers.
Fonte: Clin Infect Dis;51(3): 368-9, 2010 Aug 1.
PMID: 20597683
9.
Influenza, including the novel H1N1, in organ transplant patients.
Fonte: Curr Opin Infect Dis;23(4): 365-73, 2010 Aug.
PMID: 20581671
Resumo:
PURPOSE OF REVIEW: This article will review the epidemiology, diagnosis, prevention and management of influenza in solid organ transplant recipients. RECENT FINDINGS: A number of recent studies have documented that influenza vaccination is both well tolerated and generally effective in producing an immunologic response in most solid organ transplant (SOT) recipients. Antiviral use is associated with improved clinical outcomes, but prolonged shedding may require a longer course of therapy th
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10.
Control of influenza in healthcare settings: early lessons from the 2009 pandemic.
Fonte: Curr Opin Infect Dis;23(4): 293-9, 2010 Aug.
PMID: 20592530
Resumo:
PURPOSE OF REVIEW: The emergence of 2009 pandemic H1N1 influenza A (pH1N1) has provided a unique challenge to influenza control in healthcare settings. We provide an overview of the early lessons from the 2009 pandemic. RECENT FINDINGS: The modes of influenza transmission and their contributions to the development of infections remain unclear. Recent studies in the guinea pig model have demonstrated airborne transmission, but data from human studies and outbreaks are inconclusive. Data on p
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11.
It is not just AIV: from avian to swine-origin influenza virus.
Fonte: Sci China Life Sci;53(1): 151-3, 2010 Jan.
PMID: 20596968
12.
[In Process Citation]
Fonte: Sante Publique;22(2): 249-52, 2010 Mar-Apr.
PMID: 20598191
Resumo:
The rightfulness and relevance of the use of fear appeals in prevention are not debated in France. However, it seems that the recent failure of the H1N1 influenza vaccination, following many political and journalistic speeches mainly focused on the fear of the illness and its consequences, should challenge policy-makers about the choice of this communication means. Other methods, founded on the results of an "emotional epidemiology" of the epidemic and based on community health approaches, could have been usefully applied.

