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Fonte: Clin Lab;59(3-4): 337-42, 2013.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23724623
Resumo: BACKGROUND: Influenza has emerged every year but a complete profile of laboratory indices throughout the disease course remains unknown. METHODS: Clinical data was collected from 28 confirmed cases of the pandemic influenza H1N1 2009. The levels of serum iron (Fe), carbon dioxide combining power (CO2-CP), total complement hemolytic activity (CH50), C-reactive protein (CRP), and white blood cell (WBC) and differential count were analyzed. RESULTS: Major laboratory abnormalities recokled for (mais)
Health care versus non-health care businesses' experiences during the 2009 H1N1 pandemic: Financial impact, vaccination policies, and control measures implemented.
Fonte: Am J Infect Control;41(6): e49-54, 2013 Jun.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23374539
Resumo: BACKGROUND: Only limited data are available on businesses' experiences related to the 2009 H1N1 pandemic in terms of interventions implemented, staffing shortages, employees working while ill, and H1N1 vaccination policy. METHODS: A questionnaire was administered to human resource professionals during May-July 2011 to assess US businesses' experiences related to the 2009 pandemic. Logistic regressions were used to describe factors associated with providing H1N1 and respiratory hygiene train (mais)
Impact of 13-valent pneumococcal conjugate vaccine (PCV13) in a pandemic similar to the 2009 H1N1 in the United States.
Fonte: BMC Infect Dis;13: 229, 2013.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23687999
Resumo: BACKGROUND: High rates of bacterial coinfection in autopsy data from the 2009 H1N1 influenza ("flu") pandemic suggest synergies between flu and pneumococcal disease (PD) during pandemic conditions, and highlight the importance of interventions like the 13-valent pneumococcal conjugate vaccine (PCV13) that may mitigate the impact of a pandemic. METHODS: We used a decision-analytic model, estimated from published sources, to assess the impact of pediatric vaccination with PCV13 versus the 7-v (mais)
A Comparative Study of the Effects of Whole Red Ginseng Extract and Polysaccharide and Saponin Fractions on Influenza A (H1N1) Virus Infection.
Fonte: Biol Pharm Bull;36(6): 1002-7, 2013.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23727921
Resumo: Total extracts of ginseng (the root of Panax ginseng C. A. Meyer) and saponin and polysaccharide fractions have been the main products used to investigate novel effects of ginseng over the last five decades. However, the differences if any between the pharmacological effects of total extract and saponin and polysaccharide fractions are largely unknown. In this study, we compared their effects on influenza A virus infection. Mice received total extract of Korean red ginseng (RG), and polysac (mais)
Fonte: J Autoimmun;43: 26-31, 2013 Jun.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23497937
Resumo: In recent years, a growing number of potential autoimmune disorders affecting neurons in the central nervous system have been identified, including narcolepsy. Narcolepsy is a lifelong sleep disorder characterized by excessive daytime sleepiness with irresistible sleep attacks, cataplexy (sudden bilateral loss of muscle tone), hypnagogic hallucinations, and abnormalities of Rapid Eye Movement sleep. Narcolepsy is generally a sporadic disorder and is caused by the loss of hypocretin (orexin) (mais)
Fonte: Vaccine;31(27): 2874-8, 2013 Jun 12.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23623863
Resumo: OBJECTIVE: Despite pregnant women's increased morbidity and mortality from influenza, vaccination rates remain low. This study intended to evaluate barriers to pregnant women's uptake of influenza vaccine. STUDY DESIGN: A survey was designed that assessed participant demographics, knowledge, beliefs, attitudes, and general experiences with seasonal and 2009 novel H1N1 influenza. Associations between patient characteristics and vaccine uptake were then assessed. RESULTS: 88 women completed t (mais)
Influenza pandemic 2009/A/H1N1 management policies in primary care: a comparative analysis of three countries.
Fonte: Aust Health Rev;37(3): 291-9, 2013 Jun.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23731961
Resumo: Background. During the influenza pandemic 2009/A/H1N1, the main burden of managing patients fell on primary care physicians (PCP). This provided an excellent opportunity to investigate the implications of pandemic policies for the PCP role. Aim. To examine policies affecting the role of PCP in the pandemic response in Australia (in the state of Victoria), Israel and England. Methods. Content analysis of the documents published by the health authorities in Australia, Israel and England durin (mais)
Fonte: Emerg Infect Dis;19(6): 879-85, 2013 Jun.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23731839
Resumo: During the past century, 4 influenza pandemics occurred. After the emergence of a novel influenza virus of swine origin in 1976, national, state, and local US public health authorities began planning efforts to respond to future pandemics. Several events have since stimulated progress in public health emergency planning: the 1997 avian influenza A(H5N1) outbreak in Hong Kong, China; the 2001 anthrax attacks in the United States; the 2003 outbreak of severe acute respiratory syndrome; and th (mais)
Fonte: PLoS One;8(5): e64555, 2013.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23734205
Resumo: BACKGROUND: Existing methods to measure influenza vaccine immunogenicity prohibit detailed analysis of epitope determinants recognized by immunoglobulins. The development of highly multiplex proteomics platforms capable of capturing a high level of antibody binding information will enable researchers and clinicians to generate rapid and meaningful readouts of influenza-specific antibody reactivity. METHODS: We developed influenza hemagglutinin (HA) whole-protein and peptide microarrays and (mais)
Health Information During the H1N1 Influenza Pandemic: Did the Amount Received Influence Infection Prevention Behaviors?
Fonte: J Community Health;38(3): 443-50, 2013 Jun.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23269499
Resumo: In the wake of uncertainty due to the H1N1 influenza pandemic, amount and sources of H1N1-related information were examined in a cohort at high-risk for respiratory complications. Factors associated with adequate amount of information were identified. A cross-sectional mailed survey was conducted in 2010 with veterans with spinal cord injuries and disorders. Bivariate comparisons assessed adequate H1N1-realted information versus not enough and too much. Multivariate regression identified va (mais)
Fonte: Nitric Oxide;31: 48-53, 2013 May 31.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23562771
Resumo: Gaseous nitric oxide (gNO) is an approved vasodilator drug for inhalation up to a maximum dose of 80ppm. While gNO has been shown, in vitro, to be an effective antibacterial agent (at 160ppm), NO-donor compounds have been shown to inhibit a variety of viruses at varying stages of replication. This research was done in order to determine whether gNO at 80 or 160ppm possesses an antiviral effect on influenza viruses. Three strains of influenza (A and B) were exposed to gNO for up to 180min, b (mais)
Impact of Influenza A(H1N1)pdm09 Virus on Circulation Dynamics of Seasonal Influenza Strains in Kenya.
Fonte: Am J Trop Med Hyg;88(5): 940-5, 2013 May.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23458953
Resumo: Abstract. We describe virus variations from patients with influenza-like illness before and after the appearance of influenza A(H1N1)pdm09 in Kenya during January 2008-July 2011. A total of 11,592 nasopharyngeal swabs were collected from consenting patients. Seasonal influenza B, A/H1N1, A/H3N2, A/H5N1, and influenza A(H1N1)pdm09 viruses were detected by real-time reverse transcription-polymerase chain reaction. Of patients enrolled, 2073 (17.9%) had influenza. A total of 1,524 (73.4%) of 2 (mais)