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Resultados  1-12 de 9.378
1.

Response of BALB/c mice to a monovalent influenza A (H1N1) 2009 split vaccine.

Autor(es): Yang P; Xing L; Tang C; Jia W; Zhao Z; Liu K; Gao X; Wang X
Fonte: Cell Mol Immunol;7(2): 116-22, 2010 Mar.
PMID: 20118968
Resumo: The novel influenza A (H1N1) 2009 virus has emerged to cause the first pandemic of the twenty-first century. Disease outbreaks caused by the influenza A (H1N1) virus have prompted concerns about the potential for a pandemic and have driven the development of vaccines against this subtype of influenza A. In this study, we developed a monovalent influenza A (H1N1) split vaccine and evaluated its effects in BALB/c mice. Mice were immunized subcutaneously with 2 doses of the vaccine containing (mais)
2.

Optimal resource allocation model to mitigate the impact of pandemic influenza: a case study for Turkey.

Autor(es): Koyuncu M; Erol R
Fonte: J Med Syst;34(1): 61-70, 2010 Feb.
PMID: 20192056
Resumo: Pandemic influenza has been considered as a serious international health risk by many health authorities in the world. In mitigating pandemic influenza, effective allocation of limited health resources also plays a critical role along with effective use of medical prevention and treatment procedures. A national resource allocation program for prevention and treatment must be supported with the right allocation decisions for all regions and population risk groups. In this study, we develop a (mais)
3.

Uncertainties on the frontier: rescue therapy in pandemic influenza.

Autor(es): Munro CL
Fonte: Am J Crit Care;19(2): 104-7, 2010 Mar.
PMID: 20194604
4.

Hospitalized patients with novel influenza A (H1N1) virus infection: Shanghai, June - July 2009.

Autor(es): Xiao H; Lu SH; Ou Q; Chen YY; Huang SP
Fonte: Chin Med J (Engl);123(4): 401-5, 2010 Feb.
PMID: 20193477
Resumo: BACKGROUND: From late May 2009, sporadic imported cases of novel influenza A (H1N1) were continuously confirmed in Shanghai, but there were few reports on its clinical presentation in China. The aim of the study was to investigate the demographic and clinical features of the laboratory-confirmed cases and the treatment with oseltamivir. METHOD: We performed a retrospective study in the Shanghai Public Health Clinical Center (SHAPHC), reviewing the medical records of the laboratory-confirmed (mais)
5.

Influenza vaccines: from surveillance through production to protection.

Autor(es): Tosh PK; Jacobson RM; Poland GA
Fonte: Mayo Clin Proc;85(3): 257-73, 2010 Mar.
PMID: 20118381
Resumo: Influenza is an important contributor to population and individual morbidity and mortality. The current influenza pandemic with novel H1N1 has highlighted the need for health care professionals to better understand the processes involved in creating influenza vaccines, both for pandemic as well as for seasonal influenza. This review presents an overview of influenza-related topics to help meet this need and includes a discussion of the burden of disease, virology, epidemiology, viral survei (mais)
6.

Performance of a Rapid Influenza Test in Children During the H1N1 2009 Influenza A Outbreak.

Autor(es): Cruz AT; Demmler-Harrison GJ; Caviness AC; Buffone GJ; Revell PA
Fonte: Pediatrics;125(3): e645-50, 2010 Mar.
PMID: 20156902
Resumo: OBJECTIVE: To evaluate the performance of a rapid influenza diagnostic test (RIDT) in detecting H1N1 2009 influenza A virus in respiratory samples from pediatric patients in comparison to that of real-time reverse-transcriptase polymerase chain reaction (rRT-PCR) and viral culture. Methodology. This was a cross-sectional diagnostic-accuracy study conducted at a tertiary care children's hospital. Patients for whom the RIDT (BinaxNOW [Binax, Inc, Portland, ME]), viral culture, and rRT-PCR res (mais)
7.

Sensitivity of Rapid Influenza Diagnostic Testing for Swine-Origin 2009 A (H1N1) Influenza Virus in Children.

Autor(es): Hawkes M; Richardson SE; Ipp M; Schuh S; Adachi D; Tran D
Fonte: Pediatrics;125(3): e639-44, 2010 Mar.
PMID: 20156906
Resumo: BACKGROUND: The rapidly evolving pandemic of novel 2009 swine-origin influenza A (H1N1) virus (S-OIV) demands that accurate and practical diagnostics be urgently evaluated for their potential clinical utility. OBJECTIVE: To determine the diagnostic accuracy of a rapid influenza diagnostic test (RIDT) and direct fluorescent antibody (DFA) assay for S-OIV by using reverse-transcription polymerase chain reaction (RT-PCR) as the reference standard. METHODS: We prospectively recruited children ( (mais)
8.

[Vaccinology update 2009: questions around the safety of adjuvanted influenza A(H1N1) vaccines]

Autor(es): Siegrist CA
Fonte: Rev Med Suisse;6(231): 67-70, 2010 Jan 13.
PMID: 20196437
Resumo: This manuscript reviews the main vaccine safety concerns that have limited the confidence of the population vis-a-vis influenza A(H1N1) vaccines and disturbed health professionals: A hasty development process? Excessively strong adjuvants? Notoriously toxic substances such as squalene and mercury salts? High risks of Guillain-Barre syndrome or auto-immune diseases? Deaths and other severe problems following immunization? Providing the available information, this manuscript asks whether a hi (mais)
9.

Swine-origin influenza A (H1N1) in Indian children.

Autor(es): Saha A; Jha N; Dubey NK; Gupta VK; Kalaivani M
Fonte: Ann Trop Paediatr;30(1): 51-5, 2010.
PMID: 20196934
Resumo: BACKGROUND: Swine-origin influenza A H1N1 (S-OIV) has not been systematically studied in Indian children. OBJECTIVES: To study the clinical characteristics, morbidity and mortality pattern in children with S-OIV infection. METHODS: This prospective study was conducted during the 'containment phase' of the pandemic in New Delhi from 10 June to 5 August 2009. All children suspected of being infected by S-OIV were admitted to the isolation wards and clinically evaluated according to WHO guidel (mais)
10.

All health professionals should receive the 2009 H1N1 influenza vaccine.

Autor(es): Seppelt IM; Webb SA; Booy R
Fonte: Crit Care Resusc;12(1): 3-5, 2010 Mar.
PMID: 20196706
11.

Prone positioning of influenza H1N1 2009 patients with acute respiratory distress syndrome.

Autor(es): Bayya Ael R; Linton DM
Fonte: Crit Care Resusc;12(1): 67, 2010 Mar.
PMID: 20196717
12.

Assessment of the Efficacy of Commercially Available and Candidate Vaccines against a Pandemic H1N1 2009 Virus.

Autor(es): Kobinger GP; Meunier I; Patel A; Pillet S; Gren J; Stebner S; Leung A; Neufeld JL; Kobasa D; von Messling V
Fonte: J Infect Dis;201(7): 1000-6, 2010 Apr 1.
PMID: 20170374
Resumo: Background. The emergence and global spread of the pandemic H1N1 2009 influenza virus have raised questions regarding the protective effect of available seasonal vaccines and the efficacy of a newly produced matched vaccine. Methods. Ferrets were immunized with the 2008-2009 formulations of commercially available live attenuated (FluMist; MedImmune) or split-inactivated (Fluviral; GlaxoSmithKline) vaccines, a commercial swine vaccine (FluSure; Pfizer), or a laboratory-produced matched inact (mais)
Resultados  1-12 de 9.378
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