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Risk Factors for Influenza among Health Care Workers during 2009 Pandemic, Toronto, Ontario, Canada.
Fonte: Emerg Infect Dis;19(4): 606-15, 2013 Apr.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23631831
Resumo: This prospective cohort study, performed during the 2009 influenza A(H1N1) pandemic, was aimed to determine whether adults working in acute care hospitals were at higher risk than other working adults for influenza and to assess risk factors for influenza among health care workers (HCWs). We assessed the risk for influenza among 563 HCWs and 169 non-HCWs using PCR to test nasal swab samples collected during acute respiratory illness; results for 13 (2.2%) HCWs and 7 (4.1%) non-HCWs were pos (mais)
Fonte: Emerg Infect Dis;19(4): 616-22, 2013 Apr.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23631838
Resumo: Current estimates of deaths from the influenza pandemic of 1918-19 in Japan are based on vital records and range from 257,000 to 481,000. The resulting crude death rate range of 0.47%-0.88% is considerably lower than parallel and conservative worldwide estimates of 1.66%-2.77%. Because the accuracy of vital registration records for early 20th century Asia is questionable, to calculate the percentage of the population who died from the pandemic, we used alternative prefecture-level populatio (mais)
Fonte: Emerg Infect Dis;19(4): 644-7, 2013 Apr.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23631999
Resumo: Active surveillance in health care centers in Gabon during 2009-2011 detected 72 clinical cases of pandemic (H1N1) 2009 (pH1N1). We found that pH1N1 virus was introduced in mid-2009 but spread throughout the country in 2010. Thus, Gabon was also affected by pH1N1.
Health Information During the H1N1 Influenza Pandemic: Did the Amount Received Influence Infection Prevention Behaviors?
Fonte: J Community Health;38(3): 443-50, 2013 Jun.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23269499
Resumo: In the wake of uncertainty due to the H1N1 influenza pandemic, amount and sources of H1N1-related information were examined in a cohort at high-risk for respiratory complications. Factors associated with adequate amount of information were identified. A cross-sectional mailed survey was conducted in 2010 with veterans with spinal cord injuries and disorders. Bivariate comparisons assessed adequate H1N1-realted information versus not enough and too much. Multivariate regression identified va (mais)
Fonte: Nitric Oxide;31: 48-53, 2013 May 31.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23562771
Resumo: Gaseous nitric oxide (gNO) is an approved vasodilator drug for inhalation up to a maximum dose of 80ppm. While gNO has been shown, in vitro, to be an effective antibacterial agent (at 160ppm), NO-donor compounds have been shown to inhibit a variety of viruses at varying stages of replication. This research was done in order to determine whether gNO at 80 or 160ppm possesses an antiviral effect on influenza viruses. Three strains of influenza (A and B) were exposed to gNO for up to 180min, b (mais)
Impact of Influenza A(H1N1)pdm09 Virus on Circulation Dynamics of Seasonal Influenza Strains in Kenya.
Fonte: Am J Trop Med Hyg;88(5): 940-5, 2013 May.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23458953
Resumo: Abstract. We describe virus variations from patients with influenza-like illness before and after the appearance of influenza A(H1N1)pdm09 in Kenya during January 2008-July 2011. A total of 11,592 nasopharyngeal swabs were collected from consenting patients. Seasonal influenza B, A/H1N1, A/H3N2, A/H5N1, and influenza A(H1N1)pdm09 viruses were detected by real-time reverse transcription-polymerase chain reaction. Of patients enrolled, 2073 (17.9%) had influenza. A total of 1,524 (73.4%) of 2 (mais)
A Subregional Analysis of Epidemiologic and Genetic Characteristics of Influenza A(H1N1)pdm09 in Africa: Senegal, Cape Verde, Mauritania, and Guinea, 2009-2010.
Fonte: Am J Trop Med Hyg;88(5): 946-53, 2013 May.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23509122
Resumo: Abstract. During the pandemic 2009 episode, we conducted laboratory-based surveillance in four countries from West Africa: Senegal, Mauritania, Cape Verde, and Guinea. Specimens were obtained from 3,155 patients: 2,264 patients from Senegal, 498 patients from Cape Verde, 227 patients from Mauritania, and 166 patients from Guinea; 911 (28.9%) patients were positive for influenza, 826 (90.7%) patients were positive for influenza A, and 85 (9.3%) patients were positive for influenza B. Among t (mais)
Safety of the Pandemic H1N1 Influenza Vaccine Among Pregnant U.S. Military Women and Their Newborns.
Fonte: Obstet Gynecol;121(3): 511-8, 2013 Mar.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23635612
Resumo: OBJECTIVES: : To assess adverse pregnancy outcomes among active-duty U.S. military women who received pandemic H1N1 vaccine during pregnancy as well as adverse health outcomes among the newborns resulting from these pregnancies. METHODS: : The primary study population was a retrospective cohort of active-duty U.S. military women vaccinated during pregnancy with either the pandemic H1N1 vaccine between October 2009 and June 2010 or with seasonal influenza vaccine between October 2008 and Jun (mais)
Committee opinion: no. 563: ethical issues in pandemic influenza planning concerning pregnant women.
Fonte: Obstet Gynecol;121(5): 1138-43, 2013 May.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23635767
Resumo: : Pregnant women traditionally have been assigned priority in the allocation of prevention and treatment resources during outbreaks of influenza because of their increased risk of morbidity and mortality. The Committee on Ethics of the American College of Obstetricians and Gynecologists explores ethical justifications for assigning priority for prevention and treatment resources to pregnant women during an influenza pandemic, makes recommendations to incorporate ethical issues in pandemic i (mais)
Effects of age on H1N1-specific serum IgG1 and IgG3 levels evaluated during the 2011-2012 influenza vaccine season.
Fonte: Immun Ageing;10(1): 14, 2013.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23607926
Resumo: BACKGROUND: We have previously reported an age-related impairment in the serum antibody response to pandemic (p)2009 H1N1, measured by hemagglutination inhibition assay and ELISA. The present study extends these observations and evaluates IgG subclass distribution in healthy individuals of different ages vaccinated during the 2011-2012 season. RESULTS: The 2011-2012 vaccination season was characterized by a vaccine containing the pandemic (p)2009 H1N1 strain for the third consecutive year. (mais)
Fonte: Virol J;10(1): 111, 2013.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23575279
Resumo: BACKGROUND: The influenza pandemics have resulted in significant morbidity and mortality worldwide. Animal models are useful in the study of influenza virus pathogenesis. Because of various limitations in current laboratory animal models, it is essential to develop new alternative animal models for influenza virus research aimed at understanding the viral and host factors that contribute to virus infection in human. METHOD: We investigated the replicative efficiency of influenza H1N1 virus (mais)
Intervention strategies for emerging respiratory virus infections: policy and public health considerations.
Fonte: Curr Opin Virol;3(2): 192-8, 2013 Apr.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 23477831
Resumo: Respiratory viruses have emerged and re-emerged in humans for hundreds of years. In the recent past avian and animal influenza viruses have caused human disease ranging from conjunctivitis to respiratory illnesses, including the 2009-10 A(H1N1)pdm09 pandemic. Coronaviruses, human metapneumovirus (hMPV) and enteroviruses have also impacted humans globally. Since the likely public health impacts are common, plans and policies for intervention strategies can be developed, encompassing early de (mais)