Formación docente para la educación inclusiva en instituciones públicas del Quindío / Teacher training for inclusive education in public institutions of Quindío

La formación docente es esencial dentro del proceso de educación inclusiva permitiendo responder a la diversidad de los estudiantes a partir de estrategias que promuevan su aprendizaje y participación. Este estudio analiza la formación en inclusión de 253 docentes de instituciones públicas mediante el Cuestionario de Valoración Docente de la Inclusión Educativa (CEFI-R). Los resultados indican niveles bajos de formación en las dimensiones concepciones, apoyos y metodologías. Lo que sugiere que no existe una preparación integral del profesorado para la inclusión y los planes de formación deben abordar desde aspectos conceptuales hasta la implementación de ajustes en el aula. (AU)

Teacher training is essential within the inclusive education process, allowing students to respond to diversity through strategies that promote their learning and participation. This study analyzes the inclusion training of 253 teachers in public institutions, through the Cuestionario de Valoración Docente de la Inclusión Educativa (CEFI-R). The results indicate low levels of training in the conceptual dimensions, supports and methodologies. This suggests that there is no comprehensive preparation of teachers for inclusion and training plans should address conceptual aspects to the implementation of adjustments in the classroom. (AU)

Segregación escolar del alumnado con necesidades educativas especiales en Educación Infantil en el contexto local / School segregation of students with special educational needs in Early Childhood Education in the local context

Esta investigación busca profundizar en la segregación escolar del alumnado con necesidades educativas especiales del segundo ciclo de Educación Infantil estimando su magnitud, determinando la incidencia de la titularidad del centro y de su adscripción al Programa Bilingüe y describiendo su evolución. Para ello, se realiza un estudio ex post facto con datos de los 10.182 estudiantes del segundo ciclo de Educación Infantil matriculados en alguno de los 77 centros ordinarios públicos y privados-concertados situados en dos ciudades de tamaño medio-grande de la Comunidad de Madrid. Los resultados indican que la magnitud de la segregación escolar está en torno al 0.20 (ISG); que la incidencia de la titularidad es baja (4.6 %), pero es alta la del Programa Bilingüe (17.2 % de promedio); y que la segregación ha descendido ligeramente en los últimos años, pero las diferencias entre centros atendiendo a su titularidad y adscripción al Programa Bilingüe han crecido. Con ello, se concluye que hay que prestar atención a la segregación en Educación Infantil y tomar medidas para combatirla. También se destaca la necesidad de replantear el Programa Bilingüe por su incidencia en la segregación escolar. (AU)

This research aims to explore the school segregation of students with special educational needs in the second cycle of Early Childhood Education by estimating its magnitude, determining the incidence of school ownership and affiliation to the Bilingual Program, and describing its evolution. To achieve this, we conduct an ex post facto study with data from the 10,182 students enrolled in one of the 77 public and private-subsidised schools in the Community of Madrid. The results indicate that the magnitude of school segregation is around 0.20 (ISG); that the incidence of school ownership is low (4.6 %), while the incidence of the Bilingual Program is high (17.2 % on average); and that segregation has slightly decreased in recent years, however the differences between schools based on ownership and affiliation to the Bilingual Program have increased. Therefore, we conclude that it is necessary to address segregation in Early Childhood Education and that measures need to be taken to combat it. We also highlight the importance of reconsidering the Bilingual Program due to its impact on school segregation. (AU)

Un análisis integrado entre la calidad de vida y las necesidades de apoyo de personas adultas con discapacidad intelectual en Chile / An integrated analysis between the quality of life and the support needs of adults with intellectual disabilities in Chile

El paradigma de apoyos y el de calidad de vida se han transformado en guías fundamentales para los avances en el ámbito de la discapacidad intelectual (DI). Con base en una muestra de 93 personas adultas con DI, se analiza, desde un enfoque cuantitativo no experimental, la relación entre la calidad de vida y las necesidades de apoyo, aplicando la escala INICO-FEAPS y la escala de Intensidad de Apoyos (SIS) para cada constructo. Los principales resultados evidencian que existe una relación fuerte e indirecta entre calidad de vida y necesidades de apoyos, y también la relevancia de analizar dichos resultados desde variables como grado de discapacidad, sexo o nivel socioeconómico. La discusión permite inferir la necesidad de discutir nuevas estrategias en torno a categorías como el grado de discapacidad, la autodeterminación e inclusión social, como elementos facilitadores de la calidad de vida y apoyos desde un enfoque integral que contribuya al desarrollo de estrategias de programas sociales para la población con DI. (AU)

The support paradigm and the quality of life paradigm have become fundamental guides for progress in the field of Intellectual Disability (ID). Based on a sample of 93 adults with ID, the relationship between Quality of Life and Support Needs is analyzed from a non-experimental quantitative approach, applying the INICO-FEAPS scale and the SIS Support Intensity scale for each construct. The main results show that there is a strong and indirect relationship between quality of life and support needs, and the relevance of analyzing these results from variables such as the degree of disability, sex or socioeconomic level. The discussion allows us to infer the need to discuss new strategies around categories such as the degree of disability, self-determination and social inclusion, as facilitating elements of quality of life and supporting a comprehensive approach that contributes to the development of social program strategies for the population with ID. (AU)

Estudio de prevalencia, conocimiento y control de la hipertensión arterial en barrios vulnerables de Argentina / Prevalence, knowledge and control of arterial hypertension in vulnerable neighborhoods of Argentina: A Cross-sectional Study

Introducción: La hipertensión arterial (HTA) representa el principal factor de riesgo individual, con mayor carga a nivel mundial de enfermedades cardiovasculares (ECV). En nuestro país, algunos trabajos epidemiológicos han mostrado marcadas diferencias en las prevalencias de estos factores de riesgo de acuerdo con la población evaluada. Sin embargo, no hay estudios epidemiológicos de evaluación de factores de riesgo cardiovascular exclusivos referentes a barrios vulnerables con muy bajos recursos económicos, socioculturales y poca accesibilidad a los sistemas de salud. Materiales y métodos: Estudio observacional de corte transversal multicéntrico en habitantes de comunas vulnerables de muy bajos recursos, como asentamientos populares y barrios carenciados con muestreo aleatorizado simple de casas. Se realizaron tomas de presión arterial (PA), medidas antropométricas, así como cuestionarios epidemiológicos, económicos y socioculturales. Se describen los hallazgos: prevalencia, conocimiento y control de la PA en las distintas regiones. Se efectuó una regresión logística para determinar las variables independientes a los resultados principales. Resultados: Se analizaron 989 participantes. La prevalencia de HTA global fue de 48,2%. Un total de 82% tenía un índice de masa corporal (IMC) >25 kg/m2. De estos pacientes, 45,3% tenían menos de seis años de educación. Este último aspecto se asoció a mayor prevalencia de HTA de forma independiente. De los hipertensos, 44% desconocían su padecimiento y solo en 17,2% estaba controlado, asociándose esto a tener obra social (OS) y mayor nivel educativo. Únicamente 24% estaban bajo tratamiento combinado. Conclusión: La prevalencia de HTA en barrios vulnerables es elevada, superando a la de otros estratos sociales con niveles de conocimiento, tratamiento y control de la HTA bajos, similar a otras poblaciones. Se detectó un uso insuficiente de la terapia combinada.

Introduction: Hypertension (HTN) represents the primary individual risk factor, contributing significantly to the global burden of cardiovascular diseases (CVD). In our country, epidemiological research has highlighted substantial variations in the prevalence of these risk factors across different populations. However, there is a lack of epidemiological studies assessing exclusive cardiovascular risk factors within vulnerable neighborhoods characterized by extremely limited economic resources, sociocultural challenges, and inadequate healthcare access. Methods: A multicenter cross-sectional observational study was conducted among individuals residing in economically deprived and marginalized communities, including informal settlements and underprivileged neighborhoods. Simple random sampling of households was employed. Blood pressure measurements, anthropometric assessments, and epidemiological, economic, and sociocultural questionnaires were administered. Results encompass prevalence rates, awareness levels, and blood pressure control across diverse regions. Logistic regression was utilized to identify independent variables influencing primary outcomes. Results: A total of 989 participants were analyzed. The overall prevalence of hypertension was 48.2%. About 82% had a body mass index (BMI) >25. Approximately 45.3% had less than 6 years of formal education. Independent association was established between education levels below 6 years and higher hypertension prevalence Among hypertensive individuals, 44% were unaware of their condition, with only 17.2% achieving control, correlated with having health insurance and a higher educational background. Merely 24% were receiving combined therapy. Conclusion: The prevalence of hypertension within vulnerable neighborhoods is alarmingly high, surpassing rates in other social strata. Knowledge, treatment, and control levels of hypertension are suboptimal, comparable to other populations... (AU)

Realidad investigadora de los enfermeros en atención primaria de salud: ¿cuál es la situación? / Research reality of nurses in primary health care: what is the situation?

Objetivo: Examinar la actividad investigadora de los enfermeros en atención primaria de salud y conocer su divulgación. Metodología: Se trata de un estudio transversal descriptivo realizado entre el 27 mayo hasta el 29 de junio de 2022, en un Área de Gestión Sanitaria a través de un cuestionario electrónico autoadministrado. Contestaron el cuestionario 242 enfermeros. Un 5.2% posee el grado de Máster y ninguno el de Doctor. Un 8.3% ha colaborado en algún proyecto de investigación financiado, siendo la suscripción a grupos del Plan Andaluz de Investigación, Desarrollo e Innovación (PAIDI) de un 0,4%. La participación es principalmente colaborativa con sólo 1 caso como IP en proyectos financiados. La aportación a congresos u otras actividades de divulgación es de un 23% para comunicaciones orales y de un 26,1 % para comunicaciones escritas. Resultados: Sobre la publicación de resultados, un 16,5%, han publicado al menos 1 artículo científico, siendo un 1,3% en revistas de impacto (ninguna en Q1 y Q2). La temática de las publicaciones es muy diversa. La colaboración en investigaciones realizadas con otras disciplinas ha sido de un 10,4 % y en estudios de investigación realizados con otras instituciones o servicios de salud de un 11,3%. Conclusión: Se concluye que la actividad investigadora realizada en atención primaria es de bajo nivel y calidad. Existe dispersión tanto en la temática como en los perfiles enfermeros que desarrollan actividad investigadora, lo que implica inexistencia de una red consolidada en investigación en cuidados que sustente la práctica asistencial basada en la evidencia científica. (AU)

Aim: The aim of this study is to examinate the research activity of nurses in primary health care and to know his dissemination. Method: It is a descriptive cross-sectional study carried out between May 27 and June 29, 2022, in a Health Management Area Through a self-administrated questionnaire. A total of 242 nurses answered the questionnaire. A total of 5,2% have a Master ́s degree and none have a PhD. Some 8,3% have collaborated in a funded research project, with 0,4% subscribing to PAIDI groups. Participation is mostly collaborative with only 1 case as PI in funded projects. Contribution to congresses or other dissemination activities is 18.7% for oral communications and 16,5% for written communications. Results: Regarding the publication of results, 16,5% have published at least 1 scientific article, 1,3% in impact journals (none in Q1 or Q2). The subject matter of the publications is very diverse. Collaboration in research with other disciplines was 10,4%, and in research studies carried out with other institutions or health services are 11,3%. Conclusion: It is concluded that the research activity carried out in primary care is of low level and quality. There is dispersion both in the subject matter and in the nursing profiles that carry out research activity, which implies the lack of a consolidated network in research in care that supports care practice based on scientific evidence. (AU)

Efectos de Cinnamomum zeylanicum en niveles glucémicos en pacientes con diabetes tipo 2: ensayo clínico aleatorizado / Effects of Cinnamomum zeylanicum on glycemic levels in patients with type 2 diabetes: Randomized clinical trial

Objetivo: Evaluar el efecto del consumo de suplemento de Cinnamomum zeylanicum (canela) en los niveles glucémicos de adultos mexicanos con diabetes tipo 2. Métodos: Se realizó un ensayo clínico aleatorizado simple ciego con 30 pacientes >18 años con diabetes tipo 2, se aleatorizaron en los grupos: intervención y control; donde consumieron cápsulas con 2 gramos de C. zeylanicum o harina de trigo (placebo) diario por 12 semanas y se midieron variables antropométricas y bioquímicas (HbA1c, GPa, triglicéridos, colesterol total, HDL y LDL). Se utilizó el software IBM SPSS versión 23 y se aplicó la prueba T-Student y U-Mann Withney para muestras independientes (según el comportamiento de la variable) para las diferencias entre grupos, valores p<0.05 fueron considerados estadísticamente significativos. Resultados: No se observaron cambios significativos en HbA1c entre grupos (p>0.05). Sin embargo, post-tratamiento el grupo intervención disminuyó significativamente HbA1c al compararlo con su línea base (-0.41%, p=0.01) mientras que no se encontraron diferencias en el grupo control (+0.03%, p=0.64). No hubo diferencias significativas en variables antropométricas ni bioquímicas. Conclusiones: El consumo de 2 g de C. zeylanicum en mexicanos con diabetes tipo 2 no produjo cambios significativos entre grupos. Se sugieren nuevos estudios donde se evalúe el suplemento de canela con una muestra mayor. ClinicalTrials.gov; NCT04023539. (AU)

Objective: To evaluate the effect of Cinnamomum zeylanicum (cinnamon) supplement use on the glycemic levels of Mexican adults with type 2 diabetes. Methods: A single-blind randomized clinical trial was conducted with 30 patients over 18 years of age with type 2 diabetes. They were randomized into intervention and control groups where they took 2-gram capsules of Cinnamomum zeylanicum or wheat flour (placebo) daily for 12 weeks; then the anthropometric and biochemical variables HbA1c, FPG, triglycerides, total cholesterol, HDL and LDL were measured. IBM SPSS version 23 software was used and the Student's t-test and Mann-Whitney U test for independent samples (according to the behavior of the variable) were applied for differences between groups, p-values <0.05 were considered statistically significant. Results: No significant changes in HbA1c were seen between the two groups (p>0.05). However, post-treatment, the HbA1c value in the intervention group decreased significantly when compared to their baseline (-0.41%, p=0.01), while no differences were found in the control group (+0.03%, p=0.64). There were no significant differences in the anthropometric or biochemical variables. Conclusions: The consumption of 2 g of Cinnamomum zeylanicum in Mexican people with type 2 diabetes did not produce significant changes between the groups. New studies evaluating cinnamon supplementation on a larger sample size are suggested. ClinicalTrials.gov; NCT04023539. (AU)

Asociación entre niveles de ansiedad y depresión en adultos con obesidad / Associação entre níveis de ansiedade e depressão em adultos com obesidade / Association between anxiety levels and depression in adults with obesity

Objetivo: Verificar la asociación entre los niveles de ansiedad y depresión en participantes de un Programa Multidisciplinario para el Tratamiento de la Obesidad, con variables antropométricas; composición corporal; parámetros bioquímicos y hemodinámicos; y aptitud física relacionada con la salud. Método: Estudio cuantitativo, correlacional, transversal, realizado con adultos participantes del Programa Multidisciplinario de Tratamiento de la Obesidad en un municipio del Noroeste de Paraná. Para la recolección de datos se aplicaron medidas antropométricas en julio de 2021; composición corporal; parámetros bioquímicos y hemodinámicos; pruebas de aptitud física relacionadas con la salud; y escala para evaluar los niveles de ansiedad y depresión. Resultados: Participaron del estudio 116 individuos, 87,94% mujeres, 12,06% hombres, con una edad media de 40 años. Hubo una correlación positiva considerable entre la hemoglobina y el hematocrito; colesterol total y LDL; glucosa y HbA1C1; peso e IMC; peso y perímetro abdominal; peso y circunferencia de la cintura; IMC y perímetro abdominal; IMC y perímetro de cintura; así como ansiedad y depresión. Conclusión: Los niveles de ansiedad y depresión de los participantes de Programa Multidisciplinario para el Tratamiento de la Obesidad no se correlacionaron significativamente con las variables de medición antropométricas; composición corporal; parámetros bioquímicos y hemodinámicos; y pruebas de evaluación de la aptitud física relacionadas con la salud. (AU)

Objetivo: Verificar associação entre níveis de ansiedade e depressão de participantes de um Programa Multiprofissional de Tratamento da Obesidade, com variáveis antropométricas; composição corporal; parâmetros bioquímicos e hemodinâmicos; e aptidão física relacionada à saúde. Método: Estudo transversal, realizado com adultos que participaram do programa em município do Noroeste do Paraná. Para a coleta de dados, aplicou-se em julho de 2021, avaliações de medidas antropométricas; composição corporal; parâmetros bioquímicos e hemodinâmicos; testes de aptidão física relacionada à saúde; e escala para avaliar os níveis de ansiedade e depressão. Resultados: Participaram do estudo 116 indivíduos, sendo 87,94% do sexo feminino, 12,06% do sexo masculino, com média de idade de 40 anos. Houve correlação positiva entre hemoglobinas e hematócritos; colesterol total e LDL; glicose e HbA1C1; peso, IMC e circunferências abdominal e de cintura; além de ansiedade e depressão. Conclusão: Os níveis de ansiedade e depressão não apresentaram correlação significativa com as variáveis estudadas. (AU)

Objective: To verify the association between levels of anxiety and depression of participants in a Multidisciplinary Program for the Treatment of Obesity, with anthropometric variables; body composition; biochemical and hemodynamic parameters; and health-related physical fitness. Method: Quantitative, correlational, cross-sectional study carried out with adults who participated in the Multidisciplinary Program for the Treatment of Obesity in a municipality in the Northwest of Paraná. For data collection, anthropometric measurements were applied in July 2021; body composition; biochemical and hemodynamic parameters; health-related physical fitness tests; and scale to assess levels of anxiety and depression. Results: 116 individuals participated in the study, 87.94% female, 12.06% male, with a mean age of 40 years. There was a considerable positive correlation between hemoglobin and hematocrit; total and LDL cholesterol; glucose and HbA1C1; weight and BMI; weight and abdominal circumference; weight and waist circumference; BMI and abdominal circumference; BMI and waist circumference; as well as anxiety and depression. Conclusion:The levels of anxiety and depression of the participants of the Multidisciplinary Program for the Treatment of Obesity did not present a significant correlation with the variables of anthropometric measurements; body composition; biochemical and hemodynamic parameters; and health-related physical fitness assessment tests. (AU)

Competencia emocional y características sociodemográficas y profesionales de las enfermeras / Competência emocionais e características sociodemográficas e profissionais de enfermeiros / Emotional competence and sociodemographic and professional characteristics of nurses

Introducción: En los profesionales de la salud, las habilidades que les permitan lidiar con las emociones propias y ajenas garantizan la calidad de la atención brindada y una relación terapéutica eficaz. Por lo tanto, son fundamentales para los enfermeros, es decir, para aquellos que actúan en las unidades de salud de la familia. Objetivo: Analizar la relación entre la competencia emocional de las enfermeras que trabajan en unidades de salud de la familia en un grupo de centros de salud en el norte de Portugal y sus características sociodemográficas y profesionales. Método: Metodología cuantitativa, de tipo transversal descriptivo-correlacional. Datos recogidos a través de un cuestionario electrónico que constaba de dos partes: características sociodemográficas y profesionales de los participantes y cuestionario de competencia emocional. 66 enfermeras compusieron la muestra. Resultados: Las enfermeras del estudio mostraron altos niveles de competencia emocional (media = 205,1, desviación estándar = 20,9). No hubo diferencias estadísticamente significativas entre las características sociodemográficas y profesionales y la competencia emocional.Conclusiones: Aunque no está clara la relación entre la competencia emocional y las características sociodemográficas y profesionales, es cierta la importancia de la inteligencia emocional en la práctica asistencial. (AU)

Introdução: Em profissionais de saúde, competências que permitam lidar com as próprias emoções e com as dos outros garantem a qualidade dos cuidados prestados e uma relação terapêutica eficaz. Daí serem fundamentais para enfermeiros, nomeadamente para os que executem funções em unidades de saúde familiares. Objetivo: Analisar a relação entre a competência emocional dos enfermeiros das unidades de saúde familiar de um agrupamento de centros de saúde do norte de Portugal e as suas características sociodemográficas e profissionais. Método: Metodologia quantitativa, do tipo transversal descritivo-correlacional. Dados recolhidos através de um questionário eletrónico que consistia em duas partes: características sociodemográficas e profissionais dos participantes e questionário de competência emocional. 66 enfermeiros compuseram a amostra. Resultados: Os enfermeiros do estudo apresentaram elevados níveis de competência emocional (média = 205,1, desvio padrão = 20,9). Não se evidenciaram diferenças estatisticamente significativas entre as características sociodemográficas e profissionais e a competência emocional. Conclusões: Apesar de não ser clara a relação entre a competência emocional e as características sociodemográficas e profissionais, é certa a importância da inteligência emocional na prática de cuidados. (AU)

Introduction: In health professionals, skills that allow them to deal with their own emotions and those of others guarantee the quality of care provided and an effective therapeutic relationship. Hence, they are fundamental for nurses, namely for those who work in family health units. Objective: To analyze the relationship between the emotional competence of nurses working in family health units in a group of health centers in the north of Portugal and their sociodemographic and professional characteristics.Method: Quantitative methodology, of the transversal descriptive-correlational type. Data collected through an electronic questionnaire that consisted of two parts: sociodemographic and professional characteristics of the participants and emotional competence questionnaire. 66 nurses composed the sample.Results: The nurses in the study showed high levels of emotional competence (mean = 205.1, standard deviation = 20.9). There were no statistically significant differences between sociodemographic and professional characteristics and emotional competence. Conclusions: Although the relationship between emotional competence and sociodemographic and professional characteristics is unclear, the importance of emotional intelligence in care practice is certain. (AU)

Trayectorias académicas de estudiantes de la Licenciatura en Enfermería de la Universidad Nacional de Tucumán a través del análisis de indicadores de rendimiento académico / Academic trajectories of nursing students at the National University of Tucumán through the analysis of academic performance indicators

Introducción: En Argentina la formación en enfermería muestra avances, pero aún no mejora el déficit cuantitativo del colectivo, ni la distribución por regiones. El análisis de las trayectorias académicas permite identificar el recorrido realizado por el estudiante en el plan de estudios y planificar instancias remediales para los aspectos que se consideren deficitarios.Objetivo: Analizar las trayectorias académicas de los estudiantes de la Licenciatura en Enfermería de la Universidad Nacional de Tucumán a través del análisis de indicadores de rendimiento académico en el periodo 2015-2019.Métodos: Estudio descriptivo, retrospectivo y cuantitativo. La población estuvo constituida por el total de estudiantes de la carrera Licenciatura en Enfermería en el período 2015-2019.Resultados: El promedio de calificaciones de la carrera es 6,35 de 10 y el promedio de duración real de la misma es de 13,35 años superando los 5 años de duración esperada. Se halló un índice de desaprobación y aplazos en el 57% de las materias del primer ciclo y el 38% del segundo.Conclusión: El rendimiento académico de las/os estudiantes de enfermería disminuyó en las últimas décadas, y esto se visibiliza en el descenso de los promedios de calificaciones y el incremento en la duración real de la carrera. Estos resultados muestran el desacople existente entre las trayectorias académicas de las/os estudiantes de enfermería, en relación con las esperadas por el sistema.(AU)

Introduction: In Argentina, nursing education shows progress, but it still does not improve the quantitative deficit of the group, nor the distribution by regions. The analysis of academic trajectories makes it possible to identify the path taken by the student in the study plan and to plan remedial measures for those aspects considered deficient. Objective: To analyze the academic trajectories of students of the bachelor’s degree in nursing at the National University of Tucumán, through the analysis of academic performance indicators in the period 2015-2019.Methodes: Descriptive, retrospective, and quantitative study. The population was constituted by the total number of students of the bachelor’s degree in nursing in the period 2015-2019.Results: The average GPA of the career is 6.35 out of 10 and the average actual duration of the career is 13.35 years, exceeding the expected duration of 5 years. A failure rate was found in 57% of the subjects of the first cycle and 38% of the second cycle.Conclusions: The academic performance of nursing students has decreased in the last decades, which can be seen in the decrease of the grade point average and the increase of the actual duration of the course. These results show the existing decoupling between the academic trajectories of nursing students in relation to those expected by the system.(AU)

Perfil clínico-epidemiológico de los pacientes ingresados en la unidad de cuidados intensivos de un hospital escuela / Perfil clínico-epidemiológico de pacientes internados em unidade de terapia intensiva de um hospital escola / Clinical-epidemiological profile of patients hospitalized in an intensive care unit of a school hospital

Objetivo: Caracterizar el perfil clínico-epidemiológico de los pacientes ingresados en la unidad de cuidados intensivos de adultos de un hospital universitario.Método: Estudio epidemiológico descriptivo, con enfoque cuantitativo, de carácter transversal y retrospectivo. La investigación se realizó en el hospital universitario, en una unidad de cuidados intensivos para adultos, entre enero y diciembre de 2021.Resultados: 153 personas fueron hospitalizadas. Hubo predominio del sexo masculino (68,6%). La edad promedio fue de 53 años (desviación estándar=20). En cuanto al municipio de residencia, predominó Maringá (39,9%). La duración media de la estancia fue de 17 días (mediana=11; desviación estándar=18). En cuanto a la causa primaria de ingreso, se observó que la causa más frecuente fue el trauma (14,4%). En cuanto al resultado de la hospitalización, aunque la mayoría de los participantes fueron dados de alta del sector (58,8%), hubo una proporción importante que falleció (37,3%).Conclusión: Predominio del sexo masculino, con edad promedio de 53 años, de la ciudad de Maringá, hospitalizados alrededor de 17 días por traumatismos y/o fracturas, que requirieron intubación y sin fármacos vasoactivos y hemodiálisis, con mayor ascenso en el sector Es frecuente, aunque la tasa de mortalidad fue del 37%, lo que genera una advertencia para los directivos.(AU)

Objetivo: Caracterizar o perfil clínico-epidemiológico dos pacientes internados na unidade de terapia intensiva adulto de um hospital escola. Método: Estudo epidemiológico descritivo, de abordagem quantitativa, recorte transversal e caráter retrospectivo. A pesquisa foi realizada no Hospital escola, em uma unidade de terapia intensiva adulto entre janeiro a dezembro de 2021. Resultados: Foram registradas 153 pessoas hospitalizadas. Houve predomínio do sexo masculino (68,6%). A idade média de 53 anos (desvio padrão=20). No que se refere ao município de residência, predominaram Maringá (39,9%). O tempo médio de internação foi de 17 dias (mediana=11; desvio padrão=18). Em relação à causa primária da admissão, percebeu-se que as mais frequentes por traumas (14,4%). Quanto ao desfecho do internamento, embora a maioria dos participantes tenha evoluído para a alta do setor (58,8%), houve um importante parcela que foi a óbito (37,3%). Conclusão: Predominância do sexo masculino, com idade média de 53 anos, oriundos da cidade de Maringá, internados por cerca de 17 dias por conta de traumas e/ou fraturas, que demandaram intubação e prescindiram de drogas vasoativas e hemodiálise, tendo como evolução mais frequente a alta do setor, embora a taxa de mortalidade tenha sido de 37%, suscitando um alerta para os gestores. (AU)

Objective: To characterize the clinical-epidemiological profile of patients admitted to the adult intensive care unit of a teaching hospital. Method: Descriptive epidemiological study, with a quantitative approach, cross-sectional and retrospective nature. The research was carried out at the teaching hospital, in an adult intensive care unit between January and December 2021. Results: 153 people were hospitalized. There was a predominance of males (68.6%). The average age was 53 years (standard deviation=20). Regarding the municipality of residence, Maringá predominated (39.9%). The average length of stay was 17 days (median=11; standard deviation=18). Regarding the primary cause of admission, it was noted that the most frequent causes were trauma (14.4%). Regarding the outcome of hospitalization, although the majority of participants were discharged from the sector (58.8%), there was an important proportion who died (37.3%). Conclusion: Predominance of males, with an average age of 53 years, from the city of Maringá, hospitalized for around 17 days due to trauma and/or fractures, which required intubation and without vasoactive drugs and hemodialysis, with a more rise in the sector is frequent, although the mortality rate was 37%, raising a warning for managers.(AU)

El equipo de enfermería frente al deterioro clínico del paciente en la sala de ingreso: una revisión integrativa / A equipa de enfermagem diante da deterioração clínica do paciente na enfermaria: uma revisão integrativa / Nursing teams facing patients' clinical deterioration in wards: an integrative review

Objetivo: Buscar, en las publicaciones científicas, la atención de enfermería que se brinda a los pacientes adultos críticos o potencialmente graves internados en las salas.Método: Revisión integradora, realizada en noviembre de 2022, en las bases de datos Web of Science, PubMed, Biblioteca Virtual en Salud, Scopus y EMBASE, utilizando la string: “nursing AND critical care AND patients’ rooms OR ward OR infirmary AND adult OR middle aged OR aged OR aged, 80 and over”.Resultados: De los 4.596 estudios encontrados, se incluyeron 19 artículos originales, publicados entre 2017 y 2022. Los contenidos se agruparon en dos categorías: “barreras para la atención de pacientes agudos en las salas de ingreso” y “oportunidades para mejorar la calidad de la atención”.Conclusión: A partir de esta revisión, fue posible extraer posibles barreras y posibilidades para mejorar la atención al paciente crítico en las salas de ingreso, que pueden servir como punto de partida para que los equipos de salud replanteen la práctica y creen estrategias para eliminar las barreras e implementar mejoras en la asistencia.(AU)

Objective: To explore, in scientific publications, the Nursing assistance provided to critically-ill or potentially serious adult patients hospitalized in wards. Method: An integrative review carried out in November 2022 in the Web of Science, PubMed, Biblioteca Virtual em Saúde, Scopus and EMBASE databases, using the following string: “nursing AND critical care AND patients’ rooms OR ward OR infirmary AND adult OR middle aged OR aged OR aged, 80 and over”. Results: Of the 4,596 studies found, 19 original articles published between 2017 and 2022 were included. Their contents were grouped into two categories: “Barriers for the care to be provided to acute patients in wards” and “Opportunities to improve care quality”. Conclusion: From this review it was possible to extract possible barriers and potentialities for advancing care for critically-ill patients in wards, which can serve as a starting point for health teams to rethink the practice and create strategies aimed at solving barriers and at implementing care improvements.(AU)

Objetivo: Explorar, nas publicações científicas, a assistência de enfermagem prestada ao paciente adulto crítico ou potencialmente grave internado nas enfermarias. Enfermería GlobalNº 74 Abril 2024Página 564Método: Revisão integrativa, realizada em novembro de 2022, nas bases Web of Science, PubMed, Biblioteca Virtual em Saúde, Scopus e EMBASE, utilizando-se a string: “nursing AND critical care AND patients’ rooms OR ward OR infirmary AND adult OR middle aged OR aged OR aged, 80 and over”. Resultados: Dos 4.596 estudos encontrados, foram incluídos 19 artigos originais, publicados entre 2017 e 2022. Os seus conteúdos foram agrupados em duas categorias: “barreiras para os cuidados ao paciente agudo nas enfermarias” e “oportunidades para a melhoria da qualidade da assistência”. Conclusão: A partir desta revisão, foi possível extrair possíveis barreiras e potencialidades para o avanço do cuidado ao paciente crítico em enfermarias, o que pode servir de ponto de partida para as equipas de saúde repensarem a prática e criarem estratégias que visem a resolução de barreiras e à implementação de melhorias na assistência.(AU)

Actuación de enfermería en la atención a la salud de parejas serodiferentes al VIH – revisión integrativa / Atuação da enfermagem na atenção à saúde de parceiros sorodiferentes ao HIV – revisão integrativa / Nursing performance in the health care of serodiscordant HIV partners – integrative review

Introducción: Las demandas de socios seropositivos al VIH han surgido con frecuencia en los servicios de atención de salud, y el enfermero como miembro del equipo de salud tiene un protagonismo en acciones que van al encuentro de las necesidades de esos usuarios.Objetivo: Identificar cuál es la actuación del enfermero en la atención a la salud de parejas serodiscordantes al VIH.Método: Se trata de una revisión integrativa, realizada en mayo y junio de 2023, en las bases de datos, Base de Datos de Enfermería (BDENF), CINAHL, MEDLINE, Web of Science y Scopus, y presentadas en el diagrama de flujo PRISMA.Resultados: Fueron seleccionados 21 artículos para la muestra final que enumeraron la actuación del enfermero junto a los compañeros serodiscordantes. Está vinculada a la atención a la salud sexual y reproductiva, acciones preventivas a la serodiscordancia, consultas de enfermería, combate al prejuicio y apoyo en la salud mental.Conclusión: Los resultados de esta revisión contribuyen a la comprensión del enfermero en cuanto a su papel ante usuarios serodiscordantes que pueden ser desarrollados en los servicios especializados y en la Atención Primaria de Salud, y detalla que el cuidado debe extenderse a las cuestiones afectivas y psicoemocionales que muchas veces los profesionales no se conciertan.(AU)

Introdução: As demandas de parceiros sorodiferentes ao HIV tem surgido com frequência nos serviços de assistência à saúde, e o enfermeiro enquanto membro da equipe de saúde tem um protagonismo em ações que vão ao encontro das necessidades desses usuários.Objetivo: Identificar qual a atuação do enfermeiro na atenção à saúde de parceiros sorodiferentes ao HIV. Método: Trata-se de uma revisão integrativa, realizada em maio e junho de 2023, nas bases de dados, Base de Dados de Enfermagem (BDENF), CINAHL, MEDLINE, Web of Science e Scopus, e apresentadas no fluxograma PRISMA. Resultados: Foram selecionados 21 artigos para a amostra final que elencaram a atuação do enfermeiro junto as parcerias sorodiferentes. Está atrelada a atenção à saúde sexual e reprodutiva, ações preventivas a sorodiferença, consultas de enfermagem, combate ao preconceito e apoio na saúde mental. Conclusão: os resultados dessa revisão contribuem para o entendimento do enfermeiro quanto ao seu papel diante de usuários sorodiferentes que podem ser desenvolvidos nos serviços especializados e na Atenção Primária à Saúde, e detalha que o cuidado deve se estender às questões afetivas e psicoemocionais que muitas vezes os profissionais não se atentam.(AU)

Introduction: The demands of HIV-serodiscordant partners have frequently emerged in health care services, and the nurse as a member of the health team has a leading role in actions that meet the needs of these users.Objective: To identify the role of nurses in the health care of HIV-serodiscordant partners.Method: This is an integrative review, carried out in May and June 2023, in the databases Nursing Database (BDENF), CINAHL, MEDLINE, Web of Science and Scopus, and presented in the FLUXPRISMA chart.Results: 21 articles were selected for the final sample that listed the role of the nurse with serodiscordant partnerships. It is linked to sexual and reproductive health care, preventive actions to serodiscordance, nursing consultations, combating prejudice and support in mental health.Conclusion: The results of this review contribute to the understanding of nurses regarding their role in relation to serodiscordant users that can be developed in specialized services and in Primary Health Care, and details that care should extend to affective and psychoemotional issues to which professionals often do not pay attention.(AU)

Induction of tomato plant biochemical immune responses by the synthesized zinc oxide nanoparticles against wilt-induced Fusarium oxysporum / Inducción de respuestas inmunes bioquímicas de la planta de tomate mediante nanopartículas de óxido de zinc sintetizadas contra Fusarium oxysporum inducido por la marchitez

The current study used zinc oxide nanoparticles (ZnO-NPs) to protect the tomato plant against Fusarium wilt. Gamma rays were used to synthesize ZnO-NPs, and the designed ZnO-NPs were characterized using high-resolution transmission electron microscopy (HRTEM), scanning electron microscope (SEM), dynamic light scattering (DLS), energy-dispersive X-ray spectroscopy (EDX), and ultraviolet-visible (UV-Vis.) spectroscopy. We found that the 20 kGy dose is the most effective for ZnO-NPs synthesis, with the highest O.D. = 1.65 (diluted 3 times) at 400 nm. The scale of ZnO-NPs ranged from 10.45 to 75.25 nm with an average diameter of 40.20 nm. The results showed that the designed ZnO-NPs showed promising activity as a potent inducer of plant physiological immunity against Fusarium wilt disease. Likewise, ZnO-NPs significantly reduced the wilt disease symptoms incidence by 28.57% and high protection by 67.99% against F. oxysporum. Additionally, infected tomato plants treated with ZnO-NPs show improved shoot length (44.71%), root length (40.0%), number of leaves (60.0 %), chlorophyll a (36.93%), chlorophyll b (16.46%), and carotenoids (21.87%) versus infected plants. Notably, in the treatment of tomato seedlings, the beneficial effects of ZnO-NPs extended to increase not only in osmolyte contents but also total phenol contents in comparison with control plants. In conclusion, the designed ZnO-NPs can control Fusarium wilt disease and improve and develop biochemical compounds responsible for defense against fusarial infection.(AU)

Mutagenesis enhances gellan gum production by a novel Sphingomonas spp: upstream optimization, kinetic modeling, and structural and physico-functional evaluation / La mutagénesis mejora la producción de goma gellan mediante una nueva especie de Sphingomonas: optimización ascendente, modelado cinético y evaluación estructural y físico-funcional

Gellan gum (GG) has gained tremendous attention owing to its diversified applications. However, its high production and hence market cost are still a bottleneck in its widespread utilization. In the present study, high GG producing mutant of Sphingomonas spp. was developed by random mutagenesis using ethyl methylsulphonate (EMS) for industrial fermentation and identified as Sphingomonas trueperi after 16S rRNA and matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF–MS) analysis. The fermentation conditions such as pH, temperature, and inoculum ratio were optimized by one factor at a time (OFAT) followed by screening of medium components by the Plackett–Burman statistical design. The most critical nutrients were further optimized by response surface methodology for maximizing GG production. The effect of dissolved oxygen tension in bioreactor on cell growth, substrate consumption, GG production, and batch productivity was elucidated. The highest GG titer (23 ± 2.4 g/L) was attained in optimized medium at 10% inoculum (6.45 ± 0.5 log cfu/mL) under controlled fermentation conditions of pH (7), temperature (30 °C), agitation (300–600 rpm), and aeration (0.5–2.0 SLPM) at 22 ± 2% dissolved oxygen tension in a 10-L bioreactor. Kinetic modeling of optimized batch process revealed that logistic growth model could best explain biomass accumulation, while GG formation and substrate consumption were best explained by Luedeking-Piret and exponential decay model, respectively. Structural and physico-functional features of GG produced by mutant Sphingomonas spp. were characterized by HPLC, FTIR, NMR, DSC, TGA, GPC, SEM, and rheological analysis. The higher productivity (0.51 g/L/h) under optimized fermentation conditions suggests potential consideration of mutant and process for commercial utilization.(AU)

Sonoprocessing enhances the stabilization of fisetin by encapsulation in Saccharomyces cerevisiae cells / El sonoprocesamiento mejora la estabilización de fisetina mediante encapsulación en células de Saccharomyces cerevisiae

The objective of this study was to investigate for the first time the role of S. cerevisiae natural barriers and endogenous cytoplasmatic bodies on the stabilization of fisetin encapsulated via sonoprocessing coupled to freeze-drying (FD) or spray drying (SD). Both protocols of encapsulation improved the resistance of fisetin against thermal treatments (between 60 and 150 °C) and photochemical-induced deterioration (light exposition for 60 days) compared to non-encapsulated fisetin (antioxidant activity retention of approximately 55% and 90%, respectively). When stored under constant relative humidity (from 32.8 to 90%) for 60 days, yeast carriers improved the half-life time of fisetin by up to 4-fold. Spray dried particles were smaller (4.9 μm) and showed higher fisetin release after simulated gastrointestinal digestion (55.7%) when compared to FD. Freeze-dried particles, in turn, tended to agglomerate more than SD (zeta potential −19.7 mV), resulting in reduced loading features (6.3 mg/g) and less efficient protection of fisetin to heat, photo, and moisture-induced deterioration. Overall, spray-dried sonoprocessed fisetin capsules are an efficient way to preserve fisetin against harsh conditions. Altogether, this report shows that sonoprocessing coupled to drying is an efficient, creative, and straightforward route to protect and deliver lipophilic fisetin using yeast capsules for food applications.(AU)

Plant growth-promoting bacteria isolated from earthworms enhance spinach growth and its phytoremediation potential in metal-contaminated soils / Las bacterias promotoras del crecimiento vegetal aisladas de lombrices de tierra mejoran el crecimiento de las espinacas y su potencial de fitorremediación en suelos contaminados con metales

The aim of this study was to evaluate the impact of metal-tolerant plant growth-promoting bacteria (PGPB) isolated from the chloragogenous tissue of Aporrectodea molleri, which represents a unique habitat. Our objectives were to investigate their effects on the growth of Spinacia oleracea under heavy metal stress and assess their potential for enhancing phytoremediation capabilities. The experiment was conducted in an alkaline soil contaminated with 7 mg kg-1 of cadmium, 100 mg kg-1 of nickel, 150 mg kg-1 of copper, 300 mg kg-1 of Zinc, and mg kg-1 of 600 Manganese. The results showed that heavy metal stress considerably diminished root (42.8%) and shoot length (60.1%), biomass (80%), chlorophyll content (41%), soil alkaline (45%), and acid (51%) phosphatases (42%) and urease (42%). However, soil inoculation with bacterial isolates remarkably improved plant growth. Soil bioaugmentation increased spinach growth (up to 74.5% for root length, up to 106.3% for shoot length, and up to 5.5 folds for fresh biomass) while significantly increasing soil enzyme activity and NPK content. Multivariate data analysis indicated that soil inoculation with Bacillus circulans TC7 promoted plant growth while limiting metal bioaccumulation, whereas Pseudomonas sp. TC33 and Bacillus subtilis TC34 increased metal bioaccumulation in spinach tissues while minimizing their toxicity. Our study confirms that earthworms are a reservoir of multi-beneficial bacteria that can effectively improve phytoremediation efficiency and mitigate the toxic effects of heavy metals on plant growth. Further studies are needed to investigate the long-term effects and feasibility of using these isolates as a consortium in field applications.(AU)

Genetic and morphological characterization of a new genotype of nervous necrosis virus circulating among Nile tilapia in the south of Egypt

Nervous necrosis virus (NNV) is the causative agent of viral nervous necrosis in freshwater and marine fishes. In this study, NNV circulating among wild and farmed Nile tilapia (Oreochromis niloticus) was genetically and morphologically characterized using reverse transcription polymerase chain reaction (RT-PCR), sequencing analysis, and transmission electron microscopy (TEM). Brain, eye, and other organ (spleen, kidney, heart, and liver) specimens were collected from 87 wild (66) and farmed (21) Nile tilapia fish during their adult or juvenile stage at different localities in Qena and Sohag governorates in southern Egypt. Among them, 57/87 fish showed suspected NNV clinical signs, and 30/87 were healthy. The results revealed that NNV was detected in 66 out of 87 fish (58.62% in the wild and 17.24% in farmed Nile tilapia by RT-PCR), and the prevalence was higher among diseased (55.17%) than in healthy (20.69%) fish. NNV was detected in the brain, eye, and other organs. Using TEM, virion size variations based on the infected organs were observed. Nucleotide sequence similarity indicated that NNVs had a divergence of 75% from other fish nodaviruses sequenced in Egypt and worldwide. Phylogenetic analysis distinguished them from other NNV genotypes, revealing the emergence of a new NNV genotype in southern Egypt. In conclusion, NNV is circulating among diseased and healthy Nile tilapia, and a new NNV genotype has emerged in southern Egypt. (AU)

Factors associated with non-carbapenemase mediated carbapenem resistance of Gram-negative bacteria: a retrospective case-control study

Infections with carbapenemase-producing Gram-negative bacteria are related to increased morbidity and mortality, yet little is known regarding infections caused by non-beta-lactamase mediated carbapenem-resistant bacteria. Our objective was to identify risk factors for, and the clinical impact of infections caused by carbapenem-resistant carbapenemase-negative Enterobacterales and Pseudomonas aeruginosa. This retrospective matched case-control study was performed at the University Hospital of Basel, Switzerland, in 2016. We focused on other resistance mechanisms by excluding laboratory-confirmed carbapenemase-positive cases. Carbapenem resistance was set as the primary endpoint, and important risk factors were investigated by conditional logistic regression. The clinical impact of carbapenem resistance was estimated using regression models containing the resistance indicator as explanatory factor and adjusting for potential confounders. Seventy-five cases of infections with carbapenem-resistant, carbapenemase-negative bacteria were identified and matched with 75 controls with carbapenem-susceptible infections. The matched data set was well-balanced regarding age, gender, and comorbidity. Duration of prior carbapenem treatment (OR 1.15, [1.01, 1.31]) correlated with resistance to carbapenems. Our study showed that patients with carbapenem-resistant bacteria stayed 1.59 times (CI [0.81, 3.14]) longer in an ICU. The analyzed dataset did not provide evidence for strong clinical implications of resistance to carbapenems or increased mortality. The duration of prior carbapenem treatment seems to be a strong risk factor for the development of carbapenem resistance. The higher risk for a longer ICU stay could be a consequence of a carbapenem resistance. In contrast to carbapenemase-producers, the clinical impact of carbapenamase-negative, carbapenem-resistant strains may be limited... (AU)

Prevalencia de la enfermedad pulmonar esclerodermia-intersticial limitada frente a la extensa en el momento del diagnóstico de SSc-EPID según los criterios de Goh et al. Revisión sistemática y metaanálisis / Prevalence of the limited vs. extensive scleroderma-related interstitial lung disease at the time of diagnosis of SSc-ILD based on Goh et al. criteria. Systematic review and meta-analysis

Introducción: Goh et al. propusieron en 2008 un algoritmo clasificatorio de SSc-EPID limitada o extensa. La prevalencia de ambos en el momento del diagnóstico de SSc-EPID no se conoce con exactitud. Métodos: La revisión se realizó mediante MEDLINE y SCOPUS desde 2008 hasta 2023 y utilizando los términos: «sistémica», «esclerodermia» o «enfermedad pulmonar intersticial» [MesH]. Se utilizó la escala de Newcastle-Ottawa para la evaluación de la calificación de los estudios observacionales y la escala de Jadad para los ensayos clínicos. Se realizó el método inverso ponderado por la varianza. Resultados: Se incluyeron inicialmente 27 estudios en la revisión sistemática y metaanálisis (SRMA). De ellos, 17 estudios no tenían datos coincidentes. Comunicaron datos de 2.149 pacientes, 1.369 (81,2%) eran mujeres. La edad media era de 52,4 (DE 6,6) años. El 45,2% de los pacientes presentaban el subtipo difuso y el 54,8% el subtipo limitado o esclerodermia sinusal. El 38,7% de los pacientes presentaban anticuerpos antitopoisomerasa positivos y el 14,2% anticuerpos anticentrómero positivos. El porcentaje medio de capacidad vital forzada al inicio del estudio fue del 80,5% (DE 6,9) y de capacidad de difusión pulmonar para el monóxido de carbono fue del 59,1% (DE 9,6). Doce estudios presentaron datos de extensión de SSc-EPID ajustados por PFR y se incluyeron en el metaanálisis. Los 10 estudios observacionales de cohortes se analizaron por separado. El porcentaje global de afectación limitada se estimó en un 63,5% (IC del 95%: 55,3-73; p<0,001) utilizando el modelo de efectos aleatorios. La heterogeneidad entre estudios (I2) fue del 9,8% (IC del 95%: 0-68,2%). La afectación pulmonar extensa se estimó en 34,3% (IC del 95%: 26-45,4; p<0,001). La heterogeneidad entre estudios (I2) fue del 0% (IC del 95%: 0-61,6%) con el modelo de efectos aleatorios.(AU)

Introduction: Goh et al. proposed in 2008 a classificatory algorithm of limited or extensive SSc-ILD. The prevalence of both at the time of diagnosis of SSc-ILD is not known with exactitude. Methods: The review was undertaken by means of MEDLINE and SCOPUS from 2008 to 2023 and using the terms: “systemic”, “scleroderma” or “interstitial lung disease” [MesH]. The Newcastle-Ottawa Scale was used for the qualifying assessment for observational studies and the Jadad scale for clinical trials. The inverse variance-weighted method was performed. Results: Twenty-seven studies were initially included in the systematic review and meta-analysis (SRMA). Of these, 17 studies had no overlapping data. They reported data from 2,149 patients, 1,369 (81.2%) were female. The mean age was 52.4 (SD 6.6) years. 45.2% of the patients had the diffuse subtype and 54.8% had the limited or sine scleroderma subtype. A total of 38.7% of the patients showed positive antitopoisomerase antibodies and 14.2% positive anticentromere antibodies. The mean percentage of forced vital capacity at baseline was 80.5% (SD 6.9) and of diffusing capacity of the lungs for carbon monoxide was 59.1% (SD 9.6). Twelve studies presented SSc-ILD extension data adjusted for PFTs and were included in the meta-analysis. The 10 observational cohort studies were analyzed separately. The overall percentage of limited extension was estimated at 63.5% (95%CI 55.3–73; p<0.001) using the random-effects model. Heterogeneity between studies (I2) was 9.8% (95%CI 0–68.2%) with the random-effects model. Extensive pulmonary involvement was estimated at 34.3% (95%CI 26–45.4; p<0.001). Heterogeneity between studies (I2) was 0% (95%CI 0–61.6%) with the random-effects model. Conclusion: The overall percentage of limited SSc-ILD at the time of diagnosis of SSc-ILD was estimated at 63.5% and extensive at 34.3%.(AU)

Trombosis venosa cerebral / Cerebral venous thrombosis

La trombosis venosa cerebral forma parte de las llamadas trombosis en sitios inusuales. Se define como una oclusión en el territorio venoso cerebral. Su incidencia se encuentra en aumento progresivo, especialmente en países en vías de desarrollo. Se observa con más frecuencia en mujeres jóvenes, siendo los factores hormonales, como el embarazo o la anticoncepción hormonal, factores de riesgo principales en el desarrollo de esta afección. La clínica va a depender fundamentalmente de la topografía de la trombosis, con un diagnóstico de confirmación basado principalmente en las pruebas de imagen. El tratamiento consiste generalmente en la anticoagulación, pudiendo plantearse otras opciones según la gravedad del cuadro. En general, el pronóstico es mejor que el de otros trastornos vasculares intracraneales. En esta revisión se describe la evidencia actual disponible acerca de la trombosis venosa cerebral.(AU)

Cerebral venous thrombosis is part of the so-called thrombosis in unusual sites. It is defined as an occlusion in the cerebral venous territory. Its incidence is progressively increasing, especially in developing countries. It is more frequently observed in young women, with hormonal factors such as pregnancy or hormonal contraception being significant risk factors in the development of this condition. The clinical presentation will depend fundamentally on the topography of the thrombosis, with a confirmatory diagnosis based mainly on imaging tests. The treatment generally consists of anticoagulation, and other options may be considered depending on the severity of the case. Overall, the prognosis is better than that of other intracranial vascular disorders. This review describes the current evidence available regarding cerebral venous thrombosis.(AU)