Since its first
detection in
Brazil in 2015, the
Zika virus (
ZIKV ) has spread rapidly to most of the subregions of the
Americas . As of April 2016,
ZIKV autochthonous transmission has been confirmed in 35 countries and territories of
South America ,
Central America and the
Caribbean . The
Emergency Committee of the
World Health Organization (
WHO ) advised that the clusters of
microcephaly cases and other
neurological disorders in endemic areas constitute a
public health emergency of international concern (PHEIC). The global prevention and control strategy launched by
WHO /
PAHO as a strategic response framework encompasses
surveillance , response activities, and
research . There is an urgent need for additional
research to better characterize the
ZIKV outbreak and respond to this
public health emergency , especially those issues related to means of
transmission and
infection during
pregnancy and
Guillain-Barré syndrome (GBS). The
goal of the
research agenda is to support the development of evidence needed to strengthen
public health guidance and actions essential for limiting the impact of the
ZIKV outbreak. By identifying areas of high priority
research , results from this
report will assist in creating a coordinated
research agenda for the Region.