RESUMO
ABSTRACT Objective: To report nine cases of pediatric patients with Acute Lymphoid Leukemia (ALL) or Acute Myeloid Leukemia who developed severe oral mucositis (SOM) at the first week of chemotherapy. Material and Methods: The cases were selected from a sample of 105 children followed for 10 consecutive weeks. Hematological and personal data were obtained from the patient's medical records. The oral cavity was examined weekly using the modified Oral Assessment Guide. Results: More of the patients were male (55.6%), had black/brown skin (55.6%), with ALL (66.7%), and the mean age was 5.55. Two patients had values below normal for leukocytes, platelets, and creatinine over the follow-up. However, all patients showed changes in the normality of hematological data in most weeks. The most used chemotherapeutic agents were aracytin, etoposide, and methotrexate, known for their high stomatotoxic potential. Patients had 2 to 6 (mean of 4) episodes of SOM and 4 to 7 (mean of 5.5) episodes of OM. One patient at week 7, one patient at week 5, and one patient at weeks 2 and 10 did not have OM. Saliva (84 times) and lips (44 times) were the most affected items. Conclusion: The patients showed oscillations in the severity of oral mucositis and hematological parameters over the follow-up. All patients were exposed to stomatotoxic drugs during the initial phase of cancer treatment.
Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Criança , Adolescente , Estomatite/patologia , Leucemia Mieloide Aguda/diagnóstico , Leucemia-Linfoma Linfoblástico de Células Precursoras/diagnóstico , Doenças Hematológicas/tratamento farmacológico , Registros Médicos/estatística & dados numéricos , Fatores de RiscoRESUMO
Introduction: Individuals undergoing onco-hematologic treatment present higher risk for developing oral and/or systemic infections, due to the intense immunosuppression and compromise of the mucosal barriers during treatment. The aim of this study was to identify the fungal and viral oral infections that most frequently affected patients undergoing onco-hematologic treatment in a University Hospital, and relate them to the biopsychosocial data, underlying disease and treatment. Methods: This was a crosssectional study in which descriptive analysis of the data was performed, and the Exact Fisher test was applied to verify the association between the infections and the variables: sex, age group, educational level, underlying disease and treatment, considering a 5% probability of error. Results and Discussion: The clinical exam revealed that oral candidiasis was present in 8.92% of the individuals, and herpes simplex, in 4.5%. No significant associations were found between the variables and infections. The fungal and viral oral infections were little prevalente in individuals with hematologic neoplasms in the present study, suggesting that the action of dental surgeons in caring for the onco-hematologic patients at the Institution evaluated and the protocols use were efficient (AU)
Assuntos
Humanos , Masculino , Feminino , Candidíase Bucal/diagnóstico , Doenças Hematológicas , Herpes Simples/diagnóstico , Neoplasias Bucais , Estudos Transversais/métodosRESUMO
O atendimento odontológico ao portador de alterações no sangue exige que o CD esteja atento aos riscos, converse com o paciente, busque a integração com outros profissionais e conheça os recursos disponíveis, como o selante de fibrina
Assuntos
Adesivo Tecidual de Fibrina , Doenças Hematológicas , Hemofilia ARESUMO
As manifestações bucais das leucemias constituem, em alguns casos, a primeira manifestação clínica da doença, fazendo com que o reconhecimento por parte do Cirurgião Dentista seja de capital importância para o adequado encaminhamento do paciente. Neste trabalho enfocam-se os vários aspectos clínicos dessas manifestações, bem como se realça o papel do Cirurgião Dentista no controle e manutenção da saúde bucal dos pacientes leucêmicos em tratamento
