Ambient air pollutants relate to hospital admissions for chronic obstructive pulmonary disease in Ganzhou, China

ABSTRACT OBJECTIVE To evaluate the relationship between ambient air pollutants and chronic obstructive pulmonary disease in relatively low-polluted areas in China. METHODS Atmospheric pollutants levels and meteorological data were obtained from January 2016 to December 2020. The medical database including daily hospital admissions for chronic obstructive pulmonary disease (ICD10: J44) was derived from the First Affiliated Hospital of Gannan Medical University. The generalized additive model was used to analyze the percentage change with 95% confidence interval in daily hospital admissions for chronic obstructive pulmonary disease associated with a 10 µg/m3 increase in atmospheric pollutants levels. RESULTS In total, occurred 4,980 chronic obstructive pulmonary disease hospital admissions (not including emergency department visits) during 2016-2020. The mean concentrations of daily PM2.5, PM10, SO2, NO2, O3, and CO were 37.5 μg/m3, 60.1 μg/m3, 18.7 μg/m3, 23.5 μg/m3, 70.0 μg/m3, and 1.2 mg/m3 in Ganzhou. Each 10 µg/m3 increment of PM2.5, PM10, NO2, and O3 were significantly associated with 2.8% (95%CI: 1.0-4.7), 1.3% (95%CI: 0.3-2.4), 2.8% (95%CI: 0.4-5.4), and 1.5% (95%CI: 0.2-2.7) elevation in daily chronic obstructive pulmonary disease hospital admissions. The estimates of delayed effects of PM2.5, PM10, NO2, and O3 were observed at lag6, lag6, lag8, lag1, respectively. The health effects of particulate pollutants (PM2.5 and PM10) may be independent of other pollutants. The adverse effects of air pollutants were more evident in the warm season (May-Oct) than in the cold season (Nov-Apr). CONCLUSION Our study demonstrated that elevated concentrations of atmospheric pollutant (PM2.5, PM10, NO2, and O3), especially particulate pollutants, can be associated with increased daily count of hospital admissions for chronic obstructive pulmonary disease , which may promote further understanding of the potential hazards of relatively low levels of air pollution on chronic obstructive pulmonary disease and other respiratory disorders.

Exposição persistente de tela de titânio em enxerto ósseo da maxila anterior: considerações e caso clínico / Persistent exposure of titanium mesh on the anterior bone-grafted maxilla: considerations and case report

A tela de titânio é um recurso importante e amplamente utilizado em diversos tipos de enxertos ósseos. Contudo, apresenta um alto índice de exposição, o que pode comprometer total ou parcialmente o tratamento. Nesse contexto, é importante o profissional compreender diferentes formas de lidar com essa intercorrência, possibilitando o melhor prognóstico possível do enxerto, além de diminuir o desconforto do paciente. O presente trabalho apresenta um caso clínico de enxerto particulado com tela de titânio na região anterior da maxila, com exposição precoce e persistente do enxerto, mesmo frente a diferentes intervenções. O relato descreve as abordagens envolvidas em diferentes momentos da exposição e discute os aspectos teóricos e práticos envolvidos, incluindo a etiologia, os biomateriais utilizados, sua relação com exposições ao meio bucal e as prováveis razões pela quais o enxerto não apresentou perda significante de volume, mesmo após 41 dias exposto ao meio bucal.

Titanium mesh is an important and widely used resource in several types of bone grafts. However, it has a high prevalence of exposure, which may partially or totally compromise the treatment. In this sense, it is important for the professional to understand different ways of dealing with this problem, allowing the best possible prognosis of the graft, besides reducing the discomfort of the patient. The present work presents a case report of particulate graft with titanium mesh in the anterior region of the maxilla, with early and persistent graft exposure, even in front of different interventions. This report describes the approaches involved in different times of exposition and discusses the theoretical and practical aspects involved, including etiology, the biomaterials used, its relation with exposures to the oral environment and the likely reasons why the graft did not present signifi cant loss of volume, even after 41 days exposed to the mouth.