Evaluation of homeopathy effects associated with conventional periodontal therapy in randomized treatment of diabetic and non-diabetic patients with periodontitis

Periodontitis and Diabetes Mellitus type 2 (DMII) are chronic diseases treated by conventional practices and traditional medicine. In many cases, when conventional medicine cannot offer a satisfactory treatment, increases the demand for alternative therapies in chronic conditions. The aim of this study randomized was to compare and evaluate for one year clinical and serologic parameters the effects of homeopathy as an adjunct of conventional periodontal therapy in individual with periodontitis and DMII. Materials and Methods:85 individuals, of both genders, between 35 and 70 years old, participated in this randomized study, which 70 were eligible in Institute of Endocrinology and Diabetes of Rio de Janeiro-Brazil. They were divided into two groups G-1: individuals with periodontitis without systemic conditions and G-2: individuals with periodontitis and DMII. Both groups received homeopathic treatment and were evaluated in clinical and laboratorial examinations. The medication used was chosen based on the similarity principle, following the Berberis 6CH protocol (2 tablets, 2 times a day for 45 days), Mercurius Solubilis / Belladona / Hepar Sulfur-6CH (2 tablets, 3 times a day for 15 days) and a Pyrogenium 200CH biotherapeutic (single weekly dose, 2 weeks). Medications are prescribed in diluted low concentration doses for all signs and symptoms, while biotherapy is used for chronic stimulation Results:Both groups showed significant improvements throughout the study,clinical and laboratorial, at 1 year baseline: reductions in total cholesterol, triglycerides, glucose, glycated hemoglobin, uric acid and CPR. Statistical and descriptive analyzes were performed. The data obtained after laboratory analysis were tabulated and then submitted to the SPSS 17.0 software for Windows (SPSS Inc., Chicago, IL) and significance level with p <0.05. For most of parameters, G-1 performed better than G-2 (p<0.05).Conclusion:After 1 year follow-up this clinical trial suggest that homeopathy therapy, as an adjunct of periondontal treatment, improves local and systemic parameters and can provide better health condition.

Evaluation of antihyperglycemic potential of homeopathic medicines Insulinum, Pancreatinum and Uranium nitricum in Streptozotocin Induced diabetic rats

IntroductionDiabetes Mellitusis an emerging endocrine and metabolic disorder which has affected millions of people globally. Homeopathic system of medicine uses ultra-molecular doses for treatment of Diabetes Mellitus. Homeopathic medicines are prepared from plant, mineral, sarcodes,nosodes and animal parts. Insulinum 6 CH, Pancreatinum 6CH and Uranium nitricum 6 CHareused in homeopathy for treatment of Diabetes Mellitus. However,no preclinical studies have been investigated for the anti-diabetic effect and its safety.MethodsHomeopathic medicines Insulinum 6CH, Pancreatinum 6CHandUranium nitricum6CH(1012)dilution factor were used to examine antihyperglycemic effects in streptozotocin induced diabetic rats. After 28 daysoftreatment,bodyweight, Hematology, Biochemistry (serum glucose, urea, creatinine, SGPT, SGOT, ALP, Triglyceride and HDL-cholesterol), Oral Glucose Tolerance Test, HbA1C with histopathologyof (Liver, Kidney, Pancreas) weremeasured.ResultsAfter Streptozotocin induction, the animals have shown significant increase in the fasting blood glucose level (p<0.01) as compared to normal control animals. Treatment with homeopathic medicine Insulinum 6CH, Pancreatinum 6CHandUranium nitricum6CHpotency showed significant decrease in levels of Glucose (p<0.05), OGTT, Total protein (P<0.001), ALP (P<0.05), Cholesterol (P<0.001), SGPT (P<0.001), SGOT (p<0.01), Urea, HbA1C as compared to diabetic animal.ConclusionsIn the present study homeopathic medicine Insulinum 6CH, Pancreatinum 6CH andUranium nitricum6CHpotency exhibitantihyperglycemic effects in streptozotocin induced diabetic rats.(AU)

A review on preclinical studies conducted with Homeopathic medicine Cephalandra indica as an Anti-hyperglycemic agent

Background ­ Diabetes Mellitus a metabolic disorder affects the secretion of insulin from pancreas leading to hyperglycemia, if uncontrolled leads to complications triggered by free radical formed after oxidative stress. Homeopathic medicine Cephalandra Indica has shown antidiabetic activity in various potencies performed on preclinical studies on diabetic rat model. The present review highlights the pharmacological profile of homeopathic preparations Cephalandra Indica on preclinical studies and calculating the probable human equivalent dosage from preclinical studies for the pilot studies. Method ­ Articles published between January 1988 and December 2018 was included in review. Databases like PubMed ­ Medline, Google scholar were used for collecting the articles. Keywords like 'Homeopathy' or 'Homoeopathy', 'Invitro', 'Invivo' and 'Cephalandra Indica' were used. SABEH criteria were implemented for assessing methodology quality of articles. Results ­ Seven full text articles were included in review which had six Invivo studies and one Invitro study. This review article provided the scientific validation of high diluted homeopathic medicines pharmacological activity of Cephalandra Indica and probable mechanism of action confirmed through preclinical studies. Conversion of dosage from animal model to human dosage for pilot studies has been hypothetically proposed. Conclusion ­ Homeopathic medicine Cephalandra Indica has a therapeutic and safety profile with no toxicity observed in preclinical studies. The proposed hypothesis of conversion of dosage needs to be validated for further studies. (au)

Hipercalemia y su Abordaje Homeopático. Un Caso Clínico / Hyperkalemia and its Approach Homeopathic. A Clinical Case

La hipercalemia representa la complicación electrolítica más frecuente en la práctica médica. Este hecho adquiere gran importancia debido a su asociación a enfermedades como insuficiencia cardiaca (IC), diabetes mellitus (DM) o insuficiencia renal crónica (IRC), verdaderos retos para la medicina actual. Por ello, el caso clínico que se presenta resulta relevante, debido a que se trata de una paciente femenina de 72 años con IRC secundaria a una DM tipo 2 de 14 años de evolución que presenta descontrol en su glucemia, hipercalemia, anemia y gastropatía diabética manifestada por evacuaciones acuosas, indoloras y debilitantes en más de 10 ocasiones, por lo que fue hospitalizada. Su tratamiento intrahospitalario fue supervisado por el servicio de gastroenterología, nefrología, cardiología, medicina interna y nutriología. A su egreso, acude a consulta homeopática y presenta glucosa en límites normales (90 mg/dl). Sin embargo, continúa con hipercalemia leve (5.6 mEq/L) y síntomas propios de la gastropatía diabética que padece. Se le indica Kali carbonicum en potencia baja. Los resultados son positivos de manera inmediata y altamente promisorios en virtud de que baja el potasio a (4.6 mE/L) y mejora notablemente el cuadro clínico. (AU)

Hyperkalemia represents the most frequent electrolyte complication in medical practice. This fact acquires great importance due to its association to diseases such as heart failure (HF), diabetes mellitus (DM) or chronic renal failure (CRF), true challenges for current medicine. Therefore, the clinical case presented is relevant because it is a 72-year-old female patient with CRF secondary to a type 2 DM of 14 years of evolution, who has a lack of control in blood glucose, hyperkalemia, anemia and diabetic gastropathy. manifested by watery, painless, debilitating evacuations, more than 10 times, for which she was hospitalized. His in-hospital treatment was supervised by the gastroenterology, nephrology, cardiology, internal medicine and nutriology departments. Upon discharge, he goes to homeopathic consultation and presents glucose in normal limits (90 mg/dl). However, it continues with mild hyperkalemia (5.6 mEq/L) and symptoms of diabetic gastropathy. Kali carbonicum is indicated at low power. The results are immediately positive and highly promising because it lowers potassium to (4.6 mEq/L) and dramatically improves the clinical picture. (AU)

Syzygium jambolanum

A terapia com plantas medicinais vem sendo muito utilizada em váriaos países do mundo com um tratamento alternativo para doenças. O Syzygium jambolanum é amplament utilizado na medicina popular para o tratamento de diabetes, antidesentérico e no tratamento de afeçções das vias respiratórias. No Brasil é conhecido como jambolão. Devido aos altos custos com o tratamento do Diabetes a homeopatia deveria ser uma alternativa. (AU)

Diabetes, estado actual / Diabetes, present state

La diabetes mellitus (DM) abarca un grupo de desórdenes metabólicos causados por una hiperglucemia inducida por defectos en la secreción de la insulina, fallas en la acción de dicha hormona sobre los tejidos o una combinación de ambos problemas. En los últimos años, la diabetes mellitus se ha convertido en uno de los problemas de salud más importantes en México, no sólo por el considerable número de personas que la padecen, sino también por las complicaciones que genera. Cada vez es mayor la población en riesgo de padecen por causas como la obesidad, la tensión emocional, la mala alimentación y el sedentarismo. En este texto se analizan las generalidades de tan importante epidemia (como la considera la Organización Mundial de la Salud), así como los distintos tipos en que se clasifica, sus factores de riesgo, las probables complicaciones y los tratamientos que la acompañan. (AU)

Diabetes mellitus (DM) covers a group of metabolic disorders caused by hyperglycemia-induced defects in insulin secretion, failure in its hormonal action in tissues, or a combination of both. In recent years, diabetes mellitus has turn out to be one of the major health problems in Mexico, not only by the number of people who have it, but also because of the complications that they suffer. Every year the population at risk becomes higher because of obesity, lifestyle, poor diet and sedentary habits. This text discusses the general aspects of this epidemic disease (such as the WHO considers it), the different types in which is classified, as well as their risk factors, the probable complications and treatments.

Diabetes y clínica homeopática / Diabetes and homeopathic clinic

Dentro de la terapéutica médica homeopática ortodoxa lo más importante es la individualidad del paciente, la totalidad de sus síntomas y la elección medicamentosa con base en ello. La diabetes mellitus es calificada por la medicina convencional como una patología de tipo irreversible; sin embargo, siguiendo los principios homeopáticos, para un tratamiento exitoso se debe de tomar en cuenta al enfermo o paciente, y no a la enfermedad o al padecimiento. Asimismo, desde el punto de vista homeopático se buscará el equilibrio integral de los pacientes al presentar un enfoque más amplio, así como una mirada centrada en el individuo enfermo en su conjunto sin perder la importancia del diagnóstico nosológico. Diversos autores han publicado terapéuticas con indicaciones características de algunos medicamentos homeopáticos para cuadros clínicos específicos; en este artículo se realiza una revisión de los más importantes, como Henry Clay Allen, León Vannier, James Tyler Kent, John Henry Clarke y Bernardo Vijnovsky, entre otros, con el fin de proporcionarle ai lector una gama de posibilidades que van de los síntomas orgánicos hasta los mentales, semejantes a los c1asificados dentro del diagnóstico de la diabetes mellitus.

For the orthodox homeopathic medical therapeutics the most important feature is the patient's individuality, aIl symptoms and the drug choice on this basis. Diabetes mellitus is skilled in traditional medicine as an irreversible type pathology, however, following homeopathic principles, in order to get a successful treatment we must to take into account the sick or patient and not the disease or condition. Also from the homeopathic scope, fuIl balance will be sought for patients to present a more comprehensive and focused look at the individual patient as a whole without losing the importance of nosological diagnosis. Several authors have reported therapeutic with indications characteristics of some homeopathic medicines for specific clinical conditions; this article carried out a review of the most important such as Henry Clay Allen, Leon Vannier, James Taylor Kent, John Henry Clarke and Bernardo Vijnovsky, among others, with the order to provide the reader with a range of possibilities based from organic to mental symptoms similar to those ranked in the diagnosis of diabetes mellitus.

El papel de la nutrición en el control de la Diabetes Mellitus / The role of nutrition in the control of Diabetes Mellitus

La diabetes mellitus ha crecido de manera alarmante en los últimos tiempos, pero más allá de consideraciones estadísticas se debe señalar que el paciente con esta patología puede tener un buen pronóstico y una buena calidad de vida si cumple con un plan que contemple tres puntos fundamentales: un programa de ejercicio físico moderado, un tratamiento farmacológico y un plan de alimentación individualizado basado en sus preferencias alimentarias, su estilo de vida y su estado general de salud. Una buena alimentación es importante para que el organismo se mantenga en equilibrio, pero en el caso de los afectados por la diabetes será un facto r de suma relevancia para evitar complicaciones características de la enfermedad: la nefropatía diabética, la retinopatía diabética, la neuropatía diabética y los accidentes vasculares de tipo trombótico a nivel cardiaco y cerebral, entre otras. Aprender a comer, y saber que un régimen alimentario sano está muy alejado de la idea de seguir una "dieta", término que implícitamente tiene la connotación de un esfuerzo temporal para bajar de peso, es el primer paso en el control de un padecimiento que afecta a casi 10 millones de personas en México.

Diabetes mellitus has grown alarmingly in recent times, but beyond statistical considerations should be noted that patients with this condition can have a good prognostic and a quality of life if it complies with a plan that addresses three key issues: a program of moderate exercise, drug therapy and an individualized meal plan based on your food preferences, your lifestyle and your overall health. Good nutrition is important for the body to remain in balance, but in the case of those affected by diabetes it will be a paramount importance to prevent complications of the disease characteristics: diabetic nephropathy, diabetic retinopathy, diabetic neuropathy and the thrombotic vascular injury to cardiac and cerebral le among others. Learning to eat, and know that a healthy diet is far removed from the idea of following a "diet': a term that implicitly connotes a temporary effort to lose we the first step in controlling a condition affects nearly 10 million people in Mexico.

Claudicación intermitente por arteriopatía oclusiva progresiva de los miembros inferiores (AOPMI). Resultados del tratamiento homeopático (parte 1) / Claudication intermittent arterial occlusive progressive of the lower limbs (AOPMI). Results of homeopathic treatment (part 1)

Se realizó un estudio observacional descriptivo con el objetivo de mostrar el resultados del tratamiento conservador en un grupo de pacientes con Insuficiencia Arterial Crónica (IAC) sin criterios de operabilidad, atendidos en el servicio de Angiología del Hospital Provincial"Manuel Ascunce D." y seguidos en la consulta de Homeopatía de la Clínica de la Universidad Médica "Carlos J. Finlay", en el período comprendido entre Noviembro del 2004 a Julio 2005.(AU)

Revisão bibliográfica crítica: a homeopatia aplicada a indivíduos portadores de Diabetes Mellitus

O presente estudo é uma pesquisa sobre os principais trabalhos publicados na literatura médica mundial envolvendo os temas Homeopatia e Diabetes Mellitus. O objetivo deste trabalho é realizar uma revisão bilbliográfica crítica dos principais estudos publicados em revistas indexadas sobre este tema. O autor pesquisou nos sítios indexados Scielo, Pubmed, Homeoindex, Medline, Lilacs, Cochrane usando as palavras-chave Homeopatia e Diabetes mellitus. Posteriormente, classificou todos estudos de acordo com Grau de Nível de Evidência e Força de Recomendação utilizando a classificação da Associação Americana de Médicos de Família e, de acordo com saber homeopático, que corrente pertencia cada estudo. Em um total de dezoito artigos publicados envolvendo os temas homeopatia e diabetes dos quais dezesseis (88,8%) apresentaram Nìvel 3, ou seja, baixo nível de evidência e dois trabalhos apresentaram nível 2 de Evidencia, observou-se que quatro artigos (22,2%) foram realizados seguindo a linha homeopática clássica de Hahnemann, dez trabalhos (55.6%) foram baseados na linha pluralista e quatro artigos (22.2%) utilizaram ambas linhas em seus estudos. Por esta pesquisa, observa-se o baixo número de estudos publicados sobre a homeopatia e diabetes e, principalmente, a baixa qualidade destes artigos. Propõe o autor, maior número e melhores trabalhos, principalmente em sua metodologia para que seja possível melhorar a evidência e aplicabilidade da Homeopatia dentro da medicina moderna.(AU)

Desde la tribuna de materia médica Arsenicum album / From the rostrum of materia medica Arsenicum album

Corresponde al trióxido de arsénico, polvo cristalino incoloro e inodoro, de sabor ácido; poco soluble en agua. Producto natural y tóxico conocido desde la antigüedad y utilizado tanto con fines terapéuticos como de envenenamiento intencional. Actual las fuentes de exposición al As son en la industria de refinería del cobre, en plantas químicas, en los pesticidas, y en el consumo del cigarrillo.

A farmácia clínica na farmácia comunitária / Clinical Pharmacy in Community Pharmacy

Esta publicação é constituída de três parte. Na primeira parte, republicamos o Curso de Educação à Distancia " A Farmacia Clinica na Farmacia Comunitária" composto de 4 modulos, divulgados como encartes da revista "Pharmacia Brasileira" do Conselho Federal Farmácia. Este curso tornou-se possível graças à autorização e generosidade do Conselho Diretivo da Confederação Farmacéutica Argentina (COFA) que permitiu a tradução e adaptação livre da edição brasileira do mesmo, já publicado no "Correo Farmacéutico"da COFA. Módulo 1: a) Uso de denominação comum na dispensação; b) Comunicação com o paciente; c) Administração correta do medicamento. Módulo 2: a) Reação adversa a medicamentos (RAM); b) Farmacovigilância; c) Perfil farmacoterapêutico. Módulo 3: a) Interações medimentosas. Módulo 4: a) Informação e uso de medicamentos; b) Educação sanitária; c) Informação.