RESUMO
Quality control of ahomeopathic mother tincture begins with the analysis of the raw material. Once the product is obtained, some organoleptic characteristics and Physicochemical properties such as appearance, colour, odour, density, dry residue, alcohol content,and chemicalmarker are evaluated. In Brazil, mother tinctures from different suppliers may have high variability in terms of the specifications described in the homeopathic pharmacopoeia. Objective: The aim of the present study was to compare mother tinctures' quality control from different pharmaceutical suppliers based on Brazilian Homeopathic Pharmacopoeia 3rd edition. Methods: Five mother tinctures were selected according to the high number of requests in the pharmacies, also its monographs are in the Brazilian Homeopathic Pharmacopoeia (FHB) 3rd edition. The report of analysis of the product was provided by three homeopathic pharmacies from the city of Rio de Janeiro. The information in the reports wasevaluated and compared to its monograph. Results and discussion: In this study, it was found that the number of laboratories that provide homeopathic pharmaceutical ingredients is rather low. In addition, in some reports, a number of identification tests werenot described properly when compared to the monograph. Besides that, some information diverges from the pharmacopoeia, for example, absence of dry residue testing, replacement of the part of the plant used to prepare the mother tincture,and results that do not meet pharmacopoeia specifications. As can be seen, the quality and effectiveness of homeopathic medicines prepared from these tinctures may be compromised. Conclusion:In order to guarantee consumer protection and the quality and effectiveness of medicines, governments and regulatory agencies should requirea greater commitment from suppliers in the production of homeopathic inputs.
Assuntos
Controle de Qualidade , Tintura MãeRESUMO
O presente trbalho compara os resultados obtidos na impregnação de glóbulos com uma solução corante com o uso de 4 diferentes técnicas. Para cada técnica foram experimentadas simples impregnações na faixa de 2 porcento v/p à 5 porecento v/p e tríplice... (AU)
Assuntos
Métodos de Embebição , Controle de Qualidade , Glóbulos , Farmacotécnica HomeopáticaRESUMO
La fabrication de la teinture mere est standardisee par une pharmacopee. En Europe, nous retrouvons deux pharmacopees qui traitent les teinture meres homeopathiques: la pharmacopee francaise et la pharmacopee allemande. Ces textes officiels nous donnent la garantie que toute preparation portant la designation de teinture mere doit etre de qualite equivalente. Malheureusement, on constate que les regles n'offrent qu'une partie de cette garantie et que nous retrouvons encore des teintures meres d'une qualite qui ne correspond pas aux normes
Assuntos
Tintura Mãe/normas , Controle de Qualidade , Farmacotécnica HomeopáticaRESUMO
Homoeopathic medicines are being increasingly scrutinized by regulatory authorities. There is considerable variation in methods of preparation and no generally accepted standard. The authors have tested 55 different mother tinctures for anti-bacterial activity against Staphylococcus aureus, using a previously described method. Twenty mother tinctures were available from more than one manufacturer. In 40percent there were significant differences in anti-bacterial activity between tinctures from different manufacturers
Assuntos
Técnicas In Vitro , Controle de Qualidade , Tintura Mãe/farmacologia , Staphylococcus aureus , Padrões de ReferênciaRESUMO
The stability of 55 mother tinctures stored under standard conditions over a twelve month period was estimated in terms of anti-bacterial activity against Pseudomonas aeruginosa, Bacillus cereus and Staphylococcus aureus. There was little change in activity over the period
