RESUMO
Background: This study aimed to analyze the efficacy of an anti-calculus mouth rinse and its possible adverse effects on the mucosa and teeth. Material and Methods: This randomized double-blind placebo-controlled clinical trial included 40 patients with treated and managed periodontal disease, all with a history of rapid calculus formation. Patients used a pyrophos-phate-based test mouth rinse (B) or a placebo (A). A range of parameters were measured for: saliva (saliva flow, pH and chemical composition); calculus (Volpe-Manhold [V-M] index, weight, and volume); adverse effects on mucosa and teeth; and the patients subjective perceptive of mouth rinse efficacy. Results: the test mouth rinse B produced reductions in urea, uric acid, and phosphorous, calcium, saliva flow, and increases in pH. V-M index and calculus weight decreased after using the test mouth rinse. Calculus volume decreased with both mouth rinses. No changes to the mucosa or teeth were observed. Patients perceived that the test mouth rinse was more effective
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Assuntos
Humanos , Dentifrícios , Antissépticos Bucais , Cálculos Dentários , Difosfatos , Método Duplo-CegoRESUMO
El nifedipino es un agente antagonista del calcio que por sus efectos antihipertensivos es utilizado en el control de la hipertensión arterial. Se ha descrito en la literatura científica la aparición de sobrecrecimientos gingivales tras su toma, que suelen aparecer tras varios meses del inicio de la medicación. Estas alteraciones se caracterizan por un aumento de la encía a nivel de la papila interdental, que puede cubrir parcial o totalmente la corona del diente, y se ve agravada ante la presencia de placa bacteriana en personas con higiene oral deficiente. Su tratamiento incluye la remoción correcta de la placa bacteriana con un cepillado meticuloso, la eliminación de los depósitos de sarro, la realización de curetajes gingivales, y, finalmente, la realización de gingivectomías para eliminar el tejido gingival sobrante. Aunque se trata de una alteración de carácter benigno, puede ocasionar problemas estéticos y funcionales, y puede plantear, en ocasiones, la sustitución del nifedipino por otros agentes de acción similar, cuando sea posible (AU)
Nifedipine is a calcium channel blocking which, because of its antihypertensive effects, is used to control high blood pressure. There are reports in the literature of gingival overgrowth that usually appear several months after first taking this medication. These changes are characterised by increased gum around the interdental papilla that can partially or totally cover the tooth crown, which is exacerbated by the presence of bacterial plaque in patients with poor dental hygiene. Treatment includes removal of dental plaque with meticulous brushing, removal of tartar, gingival curettage, and gingivectomies to remove excess gum tissue. Although this is a benign alteration, it can produce aesthetic and functional complications, and can occasionally lead, where possible, to nifedipine being replaced by other agents of similar action (AU)
Assuntos
Humanos , Masculino , Adulto , Crescimento Excessivo da Gengiva/induzido quimicamente , Crescimento Excessivo da Gengiva/complicações , Crescimento Excessivo da Gengiva/diagnóstico , Nifedipino/administração & dosagem , Nifedipino/efeitos adversos , Nifedipino/metabolismo , Doenças da Gengiva/induzido quimicamente , Higiene Bucal/tendências , Crescimento Excessivo da Gengiva/fisiopatologia , Crescimento Excessivo da Gengiva/terapia , Doenças da Gengiva/complicações , Doenças da Gengiva/diagnóstico , Doenças da Gengiva/terapia , Placa Dentária/patologia , Cálculos Dentários/complicações , Raspagem Dentária/tendênciasRESUMO
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