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1.
Med. oral patol. oral cir. bucal (Internet) ; 27(1): e10-e17, jan. 2022. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-204328

RESUMO

Background: Beta-thalassemia major is an inherited disorder that can cause bone deformity and loss of bone mineral density. The objective of this study is to evaluate the cortical and trabecular mandibular bone morphology of children and adolescents who have beta-thalassemia major (ß-TM) using a fractal dimension (FD) analysis and different panoramic radiomorphometric indices with digital panoramic radiographic images (DPRIs).Material and Methods: The study included 80 patients (with 40 patients each of ß-TM and control). The mandibular cortical width (MCW), panoramic mandibular index (PMI), mandibular cortical index (MCI), and simple visual estimation (SVE) were evaluated, and an FD analysis of five regions of interest (ROIs) (ROI 1: in basal cortical bone; ROI 2: in premolar region; ROI 3: in molar region; ROI 4: in angulus mandible and ROI 5: in condyle region) was obtained in all DPRIs. Quantitative variables were analyzed using the student’s t-test , Kruskal–Wallis and Mann-Whitney U tests.Results: When the ß-TM groups were compared with controls, there were no statistically significant differences found in the mean FD values, the ROIs of the trabecular bone, or the SVE. There was a significant correlation in the mean MCW, PMI, ROI of cortical bone (ROI 1), and MCI between ß-TM and control groups (p < 0.001, p < 0.001, p = 0.047, and p = 0.046, respectively). The mean MCW values correlated with the SVE in both the ß-TM and control groups (p = 0.031 and p < 0.001, respectively). While the mean MCW values correlated with the MCI (p = 0.04) in the control group, the mean MCW values were not correlated with the MCI (p = 0.493) in ß-TM group.Conclusions: The current study revealed lower MCW and PMI values in the ß-TM group. While the mean FD values of trabecular bone is similar to the control groups, the mean FD value is lower in cortical bone in the ß-TM group. MCW, PMI, FD of cortical bone and MCI may be key indicators in individuals with beta-thalassemia major.(AU)


Assuntos
Humanos , Criança , Adolescente , Osso e Ossos/diagnóstico por imagem , Fractais , Mandíbula , Radiografia Dentária , Talassemia beta , Criança , Adolescente
2.
Patol. apar. locomot. Fund. Mapfre Med ; 5(1): 55-67, ene.-mar. 2007. ilus, tab
Artigo em Es | IBECS | ID: ibc-056995

RESUMO

Objetivo: analizar asistido por ordenador, imágenes densitométricas digitalizadas de cadera mediante DEXA, para determinar su utilidad en el análisis textural óptico-fractal del hueso, y diferenciar poblaciones con densidad mineral ósea (DMO) de rango normal, osteopénico u osteoporótico. Una única prueba diagnóstica, obtendría además de la DMO, otros parámetros relacionados con la estructura y resistencia ósea. Material y método: se seleccionaron imágenes densitométricas DEXA de cadera de 18 pacientes con DMO en rango normal, 16 pacientes osteopénicos y otros 16 pacientes osteoporóticos, efectuando sobre ellas un análisis morfológico, biomecánico y textural-fractal mediante el programa informático Q-Bone®. Resultados: Las variables morfológicas y biomecánicas analizadas proporcionan una información complementaria y discriminadora entre los referidos grupos. Sin embargo, el análisis textural fractal uni o multidireccional aportó escasa información adicional, aunque asociado a variables ópticas (densidad lumínica) permitió una mayor capacidad de diferenciación entre grupos de pacientes con DMO en rango normal y patológico


Objective: the computational analysis of digitized hip densitometric DXA images to determining if this type of images are useful for the optical-fractal textural analysis of bone, and, to differentiate better among populations with normal, osteopenic or osteoporótic bone mineral density (BMD) levels. Material and methods: DXA densitometric hip images of 18 patients with normal BMD, 16 patients with osteopenic BMD levels and 16 patients with osteoporotic BMD levels were selected. Morphological, biomechanical and texturalfractal analyses of these images were carried out by means of Q-Bone® software. Results: the analyzed morphological and biomechanical variables give complementary and discriminating information between the referred groups. Nevertheless, the unidirectional and multidirectional fractal textural analysis give only a little additional information, although when associated to optical variables (luminic density) seem to add a greater capacity of differentiation between groups of patients with normal and pathological BMD


Assuntos
Masculino , Feminino , Pessoa de Meia-Idade , Humanos , Osteoporose/diagnóstico , Densitometria/métodos , Densidade Óssea , Fenômenos Biomecânicos , Fractais , Análise Multivariada
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