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1.
Enferm. intensiva (Ed. impr.) ; 33(4): 225-232, Oct.- Dic. 2022. tab
Artigo em Inglês | IBECS | ID: ibc-211201

RESUMO

Background: Patients using endotracheal tubes are at high risk of oral health status dysfunction due to impaired natural airway defence, oral flora composition changes and protective substances of the teeth, medication causing xerostomia. Oral care has not been enough to manage oral mucosal dryness, so an additional topical agent is needed to protect oral mucosa to maintain oral health. Honey is one of the recommended topical agents. Objective: This study aims to identify the effect of oral care with honey as topical agents on the oral health status of patients using endotracheal tube in the Intensive Care Unit. Methods: This was an experimental study with a randomized pretest and posttest design. The sample was adult intubated patients, consisting of 36 patients. The data were analysed using the parametric test, and dependent and independent t-test. Results: The oral health score in the control group was found to be pre & post mean score11.94 and 13.28 (p=.004) respectively, while in the intervention group 11.89 and 8.33 (p<.001). Mean differences in both groups were 4.95 (p<.001) and the BOAS subscale differences were seen on the lips, gums & mucosa, and tongue (p<.05). Conclusion: Oral care with honey as a topical agent can improve the oral health status of intubated patients on the lips, gum, mucosa, and tongue subscale. Therefore, honey as an additional topical agent can be a moisturizer to maintain the oral mucosa for intubated patients in the Intensive Care Unit. Furthermore, good mucosal health will help prevent the infection and colonization of microorganisms.(AU)


Antecedentes: Los pacientes en los que se emplean tubos endotraqueales tienen un alto riesgo de padecer afectación de su salud bucal debido a la deficiencia de la defensa natural de la vía aérea, los cambios en la composición de la flora bucal y las sustancias protectoras de los dientes, ya que la medicación causa xerostomía. Los cuidados bucales no han sido suficientes para manejar la sequedad de la mucosa oral, por lo que es preciso un agente tópico para proteger dicha mucosa con vistas a mantener la salud bucal. La miel es uno de dichos agentes tópicos. Objetivo: El objetivo de este estudio es identificar el efecto de los cuidados bucales con miel como agente tópico en el estatus de la salud bucal de los pacientes en los que se han empleado tubos endotraqueales en la unidad de cuidados intensivos. Métodos: Estudio experimental con un diseño aleatorizado de pretest y postest. La muestra se compuso de 36 pacientes adultos intubados. Los datos fueron analizados utilizando una prueba paramétrica y la prueba «t» independiente. Resultados: La puntuación de la salud bucal en el grupo control reflejó una media pretest y postest de 11,94 y 13,28 (p=0,004) respectivamente, mientras que en el grupo de intervención fue de 11,89 y 8,33 (p<0,001). La media de las diferencias en ambos grupos fue de 4,95 (p<0,001), pudiéndose apreciar las diferencias de la subescala BOAS en los labios, encías y mucosa y en la lengua (p<0,05). Conclusión: Los cuidados bucales con miel como agente tópico pueden mejorar la salud bucal de los pacientes intubados en la subescala de labios, encías y mucosa y lengua. Por tanto, la miel como agente tópico adicional puede ser un agente hidratante para mantener la mucosa bucal en los pacientes intubados de la unidad de cuidados intensivos. Además, la buena salud de la mucosa ayudará a prevenir las infecciones y la colonización de microorganismos.(AU)


Assuntos
Humanos , Masculino , Feminino , Cuidados Críticos , Saúde Bucal , Intubação Intratraqueal , Mel , Assistência Centrada no Paciente , Enfermagem , Enfermagem de Cuidados Críticos , Espanha/epidemiologia , Estudos de Intervenção
2.
Nutr. hosp ; 39(5): 1093-1100, sep.-oct. 2022. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-213968

RESUMO

Introducción: las bebidas energéticas han ganado protagonismo en diferentes grupos poblacionales. Objetivo: el objetivo de esta investigación fue estudiar el efecto de la ingesta de una bebida energética rica en miel (BeeBad EnegyDrink®, Parodi Group, Italia) y una bebida energética popular con azúcares libres sobre la insulina, la glucemia, las proteínas totales y los triglicéridos. Material y métodos: quince estudiantes varones participaron en el estudio (20,85 ± 2,67 años). Se realizaron dos evaluaciones separadas en tres días. Se obtuvieron muestras sanguíneas antes de ingerir la bebida energética en estado de ayuno, 30 minutos, 60 minutos y 120 minutos después de ingerir las bebidas energéticas. El primer día, los participantes ingirieron la bebida energética rica en miel (BeeBad EnegyDrink®, Parodi Group, Italia) mientras que el segundo día los participantes ingirieron la bebida energética con azucares libres. Resultados: hubo diferencias significativas en glucosa e insulina a lo largo del tiempo (p < 0,01). Respecto a las diferencias entre bebidas energéticas, hubo diferencias en los valores de insulina, que fueron menores después de tomar la bebida energética rica en miel (p < 0,05). Además, el incremento de la glucosa e insulina a los 30 minutos fue menor tras ingerir la bebida energética rica en miel. Conclusiones: la ingesta de bebidas energéticas rica en miel produce menores elevaciones de insulina y glucosa en comparación con una bebida energética popular con azúcar libre en sujetos sanos. Atendiendo a los resultados, las bebidas energéticas ricas en miel podrían ser una alternativa a las bebidas energéticas convencionales. (AU)


Introduction: energy drinks have become more popular in different population groups. Aims: the research aimed to study the effect of the intake of a honey-rich energy drink (BeeBad EnegyDrink®, Parodi Group, Italy) and a popular energy drink with free sugars on insulin, glycemia, total protein and triglycerides. Material and methods: fifteen male students participated in the study (20.85 ± 2.67 years). Two separate evaluations were performed on three days. Blood samples were obtained before ingesting the energy drink in a fasting state, 30 minutes, 60 minutes and 120 minutes after ingesting the drinks. On the first day participants ingested the honey-rich energy drink (BeeBad EnegyDrink®, Parodi Group, Italy) while on the second day participants ingested the energy drink with free sugars. Results: there were significant differences in glucose and insulin over time (p < 0.01). Regarding the differences between energy drinks, there were differences in insulin values, being lower after taking the honey-rich energy drink (p < 0.05). In addition, the increase in glucose and insulin at 30 minutes was lower after ingesting the honey-rich energy drink. Conclusions: ingestion of honey-rich energy drink produces lower elevations of insulin and glucose compared to a popular energy drink with free sugar in healthy subjects. Based on the results, honey-rich energy drinks could be an alternative to conventional energy drinks. (AU)


Assuntos
Humanos , Masculino , Adulto Jovem , Adulto , Bebidas Energéticas/efeitos adversos , Mel , Consumo de Energia , Glucose , Insulina , Triglicerídeos
4.
Gac. sanit. (Barc., Ed. impr.) ; 35(supl. 2): S202-S205, 2021. tab, graf
Artigo em Inglês | IBECS | ID: ibc-220940

RESUMO

Objective: Cocktail honey is derived from a mixture of honey (trigona sp.), bee bread, and homogeneous royal jelly. The material has a phenolic content rich in antioxidants that are beneficial for women's reproductive health, especially for pre-conception, because it can suppress the content of free radicals in the body. Antioxidants are useful to overcome oxidative damage due to free radicals in the body that prevent various diseases from increasing fertility during pre-conception. Method: This study used the DPPH (2,2-diphenyl-1-picrylhydrazyl) test method using UV–vis spectrophotometry to express the value of free radical reduction activity as IC50 (inhibitory concentration) values. Results: The DPPH test on cocktail honey products obtained an average yield of 4577.7 μg/mL, which was included in the product category was very weak in the antioxidant activity content. Conclusion: The content contained in the honey cocktail contains weak bioactive content by assessing the antioxidant content using DPPH. The difference in the results of antioxidant activity tests using DPPH is caused by the test method and the conditions used in processing, homogeneous ingredients, solvent volume, extraction time, temperature, and pressure in product management. (AU)


Assuntos
Animais , Antioxidantes , Mel/análise , Abelhas , Suplementos Nutricionais , Radicais Livres , Fenóis/análise
5.
Gac. sanit. (Barc., Ed. impr.) ; 35(supl. 2): S251-S253, 2021. tab
Artigo em Inglês | IBECS | ID: ibc-220952

RESUMO

Objective: This study was aimed to determine the effect of ginger honey supplementation on cortisol, glutathione, and estrogen levels. The study was conducted on mice that had not yet experienced conception, and prior stress induction was carried out so that they could be continued for human trials at the preconception stage and subjects who experienced mild stress. Method: It was an in vivo study, pretest–posttest control group design. The sample of this study was 2–3 months female Balb/c mice, divided into negative control and ginger honey intervention as much as 28 mg/20 g BW for 14 days—the ELISA method used to examine cortisol hormone, glutathione levels, and estrogen levels. The mice chosen were those that had never experienced conception, and before the intervention, swimming activities were carried out on the mice until they showed symptoms of stress. Results: Results show 42 mg/20 g BW of ginger honey administration for 14 days increased 1.892 ng/dl of cortisol (p = 0.165), increased 2.438 ng/dl of glutathione (p = 0.002), and also increased 22.754 ng/ml estrogen levels in induced stress Balb/c female mice (p = 0.001). Conclusion: Ginger honey did not affect reducing cortisol levels but increasing glutathione and estrogen levels significantly. Ginger honey supplements are the potential to use as complementary therapies. (AU)


Assuntos
Humanos , Animais , Feminino , Camundongos , Glutationa/sangue , Gengibre , Mel , Hidrocortisona/sangue , Estrogênios/sangue , Camundongos Endogâmicos BALB C
6.
Gac. sanit. (Barc., Ed. impr.) ; 35(supl. 2): S291-S294, 2021. tab
Artigo em Inglês | IBECS | ID: ibc-220963

RESUMO

Objective: This study is basic research carried out to measure the nutritional content of the honey cocktail product, an herbal therapy as a complementary treatment in addressing reproductive health problems and improving the nutritional status of preconception women. The purpose of this research is to know the ingredients in honey cocktail products. Method: The stage of this study is; choose a sample, processing honey cocktail, and testing the parameters. This study used three main raw materials, namely honey, royal jelly, and bee bread. The honey used is Trigona sp. The three primary raw materials used have been processed from the Halal Center of Hasanuddin University. Honey cocktail processing will use a mixture of 100 g Trigona sp. honey, 100 g royal jelly, and 100 g bee bread, then be homogenized using a magnetic stirrer for ±15 min. Honey quality testing is conducted to determine the nutritional content of the honey cocktail supplement, such as vitamins, minerals, proteins, fats, carbohydrates, sugars (sucrose and glucose), hydroxymethylfurfural, and metals, and water. This study also examined the metal contamination, ash, and fat level. Results: The results of the test content in the cocktail honey supplement found in 100 ml containing 61.9 g carbohydrates, 0.7 g of protein, 2.3 mg of phosphorus, 0.3 mg of iron, 1736.27 μg/g of potassium, as much calcium 48.35 μg/g, 0.2 mg of manganese, 0.04 mg of fat content, and 2.84% of vitamin A. in addition, cocktail honey also contains 3.8% sucrose, 78% glucose, HMF 48.63 mg/kg, Cu <0.01 μg/g, PB 0.05 μg/g, arsenic <0.01, acidity 49.62 ml NaOH/kg, an ash content of 0.2%, and moisture content of 18.24%. Conclusion: The conclusion in this study cocktail honey samples meets the honey quality requirements following the Indonesian national standard. So that the cocktail honey supplement has good quality and is safe for consumption. (AU)


Assuntos
Animais , Mel , Saúde Reprodutiva , Estado Nutricional , Carboidratos/análise , Abelhas , Indonésia , Suplementos Nutricionais
7.
Gac. sanit. (Barc., Ed. impr.) ; 35(supl. 2): S396-S399, 2021. tab, graf
Artigo em Inglês | IBECS | ID: ibc-221033

RESUMO

Objective: The study aimed to assess the composition of MO and honey from different areas in South Sulawesi. Methods: This was a laboratory examination study. Several macro and micronutrients were measured including water, crude protein, crude lipid, Ca, Mg, Na, P, and K. Also, polyphenol and flavonoid were measured. Result: The results showed that variation of water, protein, and lipid in MO were 9.2–9.4%, 24.2–29.8%, and 8.43–9.6% respectively. Meanwhile, the variation of Ca, Mg, Na, P, K in MO were 1.63–2.2%, 0.36–0.53%, 0.18–0.43%, 012–0.22% and 0.67–0.76%, respectively. The variation of polyphenol and flavonoid of MO were 0.24–0.34% and 192–209 ppm, respectively. On the other hand, the variation of water, protein, and lipid in different types of honey were 21.1–25.4%, 1.1–1.6%, and 0.01–0.09% respectively. Meanwhile, the variation of Ca, Mg, Na, P, K in honey were 632–1040%, 216–378%, 361–555%, 20–57% and 1570–2848%, respectively. Polyphenol and flavonoids from three different kinds of honey were also varied at 0.06–011% and 14.4–35.8 ppm, respectively. Conclusion: We conclude that chemical compositions in MO from three areas were almost similar but they were varied enough in honey which was higher in Trigona sp. (AU)


Assuntos
Humanos , Animais , Mel , Moringa oleifera/química , Indonésia , Abelhas , Água , Técnicas de Laboratório Clínico
8.
Allergol. immunopatol ; 48(6): 582-588, nov.-dic. 2020. tab
Artigo em Inglês | IBECS | ID: ibc-199246

RESUMO

BACKGROUND: Apitherapy represents a certain form of complementary and alternative medicine that uses bee products in combination with other methods from this field. One of the basic concepts of this type of medicine is that all diseases can be treated using apitherapy. This study was performed to assess the recommendations from authors of books on apitherapy regarding the treatment of seasonal allergic rhinitis and compare them to findings from the scientific literature. METHODS: One hundred and twenty-nine books on apitherapy were analysed regarding recommendations for allergic seasonal rhinitis. Scientific evidence regarding the efficacy of using various bee products was searched via PubMed and JUSTfind. RESULTS: Only 38.8% of the apitherapy books mentioned seasonal allergic rhinitis. Among these books, we found 29 different recommendations in favour of bee products and one against the use of honey. The most reasonable recommendation according to clinical studies on the subject, namely the use of a mix of honey and pollen, was only found once (0.8%). CONCLUSIONS: The large discrepancies and number of different recommendations demonstrate that apitherapy is not a consistent type of medicine. The recommendations regarding seasonal allergic rhinitis in the vast majority of apitherapy books cannot be considered adequate when compared to the scientific findings


No disponible


Assuntos
Humanos , Rinite Alérgica Sazonal/terapia , Apiterapia/métodos , Livros de Texto como Assunto , Mel , Pólen , Venenos de Abelha , Terapias Complementares
10.
Enferm. clín. (Ed. impr.) ; 30(supl.3): 14-17, mar. 2020. graf, tab
Artigo em Inglês | IBECS | ID: ibc-196102

RESUMO

OBJECTIVES: This study aimed to compare the impact of honey and natural ointment based on honey-Tea Tree Oil. METHODS: This was a quasi-experimental study with a pre-post control group design approach. The sample consisted of 27 respondents in two different wound care clinics. The instruments used were the Leg Ulcer Measurement Tool (LUMT) measured on day 1, 7 and 14. Data was analyzed using paired t-test, pooled t-test, and multiple regression test. RESULTS: Most participants were female, the average age was 50.89 years, the average duration of illness for type II diabetes was 3.56 and had current infection. The results showed a significant difference in LUMT score between before and after treatment of wounds healing in the two intervention groups (p-value=0.000). CONCLUSION: Honey and natural ointment based on honey - tea tree oil significantly contributed to the healing of Diabetic Foot Ulcer


No disponible


Assuntos
Adulto , Pessoa de Meia-Idade , Idoso , Pé Diabético/terapia , Mel , Úlcera da Perna/terapia , Apiterapia , Cicatrização , Pomadas/uso terapêutico , Pé Diabético/enfermagem
12.
Ars pharm ; 60(2): 119-124, abr.-jun. 2019. tab
Artigo em Espanhol | IBECS | ID: ibc-186015

RESUMO

Objetivo: Evaluar el uso de la miel de Apis mellifera (miel de abeja) en agar base como diferenciador de oxidante-fermentador de carbohidratos en cepas de Escherichia coli ATCC 25922 y Pseudomonas aeruginosa ATCC 29212. Métodos: Se realizó un tamizaje fitoquímico preliminar de la miel de abeja. Para evaluar el uso del agar con miel de abeja como diferenciador oxidativo-fermentador, se emplearon 96 tubos de cultivo que contienen 10 mL de agar base aleatorizadas y divididas en cuatro grupos de 24 tubos: grupo I agar base con miel y Escherichia coli ATCC 25922, grupo II agar base con miel y Pseudomonas aeruginosa ATCC 29212, grupo III agar OF (Basal Medium acc. To Hugh and Leifson, Merck) con Escherichia coli ATCC 25922, y el grupo IV agar OF con Pseudomonas aeruginosa ATCC 29212; siendo el agar OF estándar. Se consideraron dos criterios de evaluación: Oxidación y Fermentación de los carbohidratos. Resultados: La miel de abeja presenta alcaloides, triterpenoides y compuestos fenólicos. Se determinó el calificativo de Bueno (100%) para el agar con miel de abeja y Escherichia coli ATCC 25922, y agar con miel de abeja y Pseudomonas aeruginosa ATCC 29212; comparado con el agar OF. Conclusión: El uso del agar con miel de Apis mellifera (miel de abeja) ha evidenciado ser bueno como alternativa al agar OF (Basal Medium acc. To Hugh and Leifson) para diferenciar Escherichia coli ATCC 25922 y Pseudomonas aeruginosa ATCC 29212 como oxidantes y fermentadoras de carbohidratos


Objective: To evaluate the use of Apis mellifera (honey) on base agar as an oxidant-carbohydrate fermentor differentiator in strains of Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 29212. Methods: Preliminary phytochemical screening of honey was carried out. Using agar with bee honey as an oxidative-fermenter differentiator, use 96 culture tubes containing 10 ml of randomized base agar and divided into four groups of 24 tubes: group I base agar with honey and Escherichia coli ATCC 25922, group II agar base with honey and Pseudomonas aeruginosa ATCC 29212, group III agar OF (basal medium according to Hugh and Leifson, Merck) with Escherichia coli ATCC 25922, and group IV agar OF with Pseudomonas aeruginosa ATCC 29212; being the standard OF agar. Two evaluation criteria were considered: Oxidation and Fermentation of carbohydrates. Results: Bee honey has alkaloids, triterpenoids and phenolic compounds. The qualifier of Good (100%) was determined for the grip with honey and Escherichia coli ATCC 25922, and agar with honey and Pseudomonas aeruginosa ATCC 29212; compared with the agar OF. Conclusion: The use of agar with honey of Apis mellifera has been shown as good as an alternative to agar OF (Basal medium according to Hugh and Leifson) to differentiate Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 29212 as oxidants and carbohydrate fermenters


Assuntos
Animais , Apis mellifica , Mel , Escherichia coli/efeitos dos fármacos , Escherichia coli/metabolismo , Pseudomonas aeruginosa/efeitos dos fármacos , Pseudomonas aeruginosa/metabolismo , Meios de Cultura/química , Meios de Cultura/farmacologia , Fermentação/efeitos dos fármacos , Estudos Transversais
13.
Enferm. clín. (Ed. impr.) ; 29(supl.1): 88-90, mar. 2019. tab
Artigo em Inglês | IBECS | ID: ibc-184780

RESUMO

Objective: The aim of this study is to determine the effectiveness of sialang honey on wound bed preparation in diabetic foot ulcer. Method: The study design was quasy experiment with one group pre test post test design approach. The sampling technique used was consecutive sampling, where respondents were selected based on the criteria that had been planned. Instrument used in this study was wound bed score, where the measurement results will be analyzed using Wilcoxon test with 95% confidence level. Result: Result of this study was average wound bed score before intervention was 2.75 and became 9.25 after the intervention on a scale of 0-16. Wilcoxon test in this study obtained p value 0.011 with the conclusion that sialang honey had a significant effect on wound bed preparation in diabetic foot ulcer. Conclusion: Statistically, honey can help the occurrence of wound bed preparation in diabetic foot ulcer


No disponible


Assuntos
Humanos , Apiterapia , Pé Diabético/terapia , Mel , Resultado do Tratamento , Cicatrização
14.
Av. odontoestomatol ; 34(6): 294-298, nov.-dic. 2018. tab
Artigo em Espanhol | IBECS | ID: ibc-182273

RESUMO

Objetivo: Comparar el efecto antibacteriano in vitro de muestras de miel de Apis mellifera producida en la Costa, Sierra y Selva contra Streptococcus mutans ATCC 25175. Material y métodos: Se evaluó el efecto en 3 grupos distribuidos en concentraciones de 100%, 50% y 25% para cada miel. Se hicieron 5 repeticiones por grupo experimental. La sensibilidad bacteriana se evaluó mediante el método de difusión en pozo. El espécimen bacteriano fue reactivado en caldo nutritivo, para inocularlo en cultivo Agar Cerebro Corazón. Resultados: Al enfrentar el microorganismo a las mieles de abeja, se obtuvo halos promedios de inhibición de 27,84 mm y 14,38 mm para las concentraciones de 100% y 50% de la miel de abeja de origen de sierra. Conclusión: sin embargo, las mieles de abeja de origen costa y selva no presentaron halos de inhibición. Se concluye que la miel de abeja de origen de Sierra al 100% y 50% tienen efecto antibacteriano sobre S. mutans ATCC 25175


Objective: To compare the in vitro antibacterial effect of samples of Apis mellifera honey produced in Costa, Sierra and Selva against Streptococcus mutans ATCC 25175. Material and methods: The effect was evaluated in 3 groups distributed in concentrations of 100%, 50 % and 25% for each honey. Five repetitions were made per experimental group. The bacterial sensitivity was evaluated by the well diffusion method. The bacterial specimen was reactivated in nutritious broth, to inoculate it in heart agar culture. Results: When facing the microorganism to the honeys of bee, average halos were obtained of inhibition of 27,84 mm and 14,38 mm for the concentrations of 100% and 50% of the honey of bee of origin of saw. Conclusion: nevertheless, bee honeys of coastal and jungle origin did not present inhibition halos. It is concluded that bee honey of Sierra origin at 100% and 50% have antibacterial effect on S. mutans ATCC 25175


Assuntos
Técnicas In Vitro/métodos , Mel , Antibacterianos/uso terapêutico , Streptococcus mutans , Apis mellifica/uso terapêutico , Espectrofotometria/métodos , Análise de Variância
15.
Rev. Rol enferm ; 41(2): 96-100, feb. 2018. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-170946

RESUMO

El cáncer de vulva es uno de los tumores ginecológicos menos frecuentes. La mutilación producida por cirugías radicales, como la vulvectomía, pueden ocasionar importantes secuelas físicas, psíquicas y sexuales en la mujer. El caso clínico que presentamos es el de una mujer de 83 años diagnosticada de cáncer de vulva, a la que se intervino en nuestro centro por recidiva local y que presentó dehiscencia de la cicatriz pocos días después de la cirugía. Nuestro objetivo es mostrar que la cura con miel es una alternativa eficaz, por sus propiedades curativas, en la cura de dehiscencias en las vulvectomías, además de ser una terapia barata, accesible y fácil de aplicar (AU)


Vulvar cancer is one of the less common gynecological tumors. Nevertheless, the mutilation produced by a radical surgery such as the vulvectomy can cause important sequels in women, both physical and psychological. We present a clinical case of an 83-year-old woman diagnosed with vulvar cancer, who underwent a radical vulvectomy after local recurrence at our hospital. She presented a wound dehiscence a few days after the surgery. Our aim is to discuss that honey is an effective alternative cure of wound dehiscence in vulvectomy due to its healing properties; it is also a cheaper treatment, accessible, and easy to apply (AU)


Assuntos
Humanos , Feminino , Idoso de 80 Anos ou mais , Neoplasias Vulvares/cirurgia , Mel/análise , Deiscência da Ferida Operatória/enfermagem , Técnicas de Fechamento de Ferimentos/enfermagem , Suturas/efeitos adversos , Cicatrização
16.
Cir. plást. ibero-latinoam ; 42(3): 217-225, jul.-sept. 2016. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-157043

RESUMO

Introducción y Objetivos. El desbridamiento enzimático de las quemaduras ha sido objeto de estudio durante décadas; en este terreno, NexoBrid(R) (MediWound Ltd., Israel) se postula como una prometedora alternativa al desbridamiento quirúrgico clásico. Por otra parte, las propiedades antibacterianas y promotoras de la cicatrización de la miel también se han evaluado recientemente con buenos resultados clínicos. Describimos nuestra experiencia preliminar con el empleo de NexoBrid(R) para el tratamiento de quemaduras faciales, seguido de curas tópicas con Medihoney(R) Wound Gel (Derma Sciences Ltd., EE.UU.). Material y Método. Incluimos en el estudio todos los pacientes atendidos en nuestra Unidad de Quemados con quemaduras faciales dérmicas o subdérmicas que afectaban a 2 o más subunidades estéticas. Realizamos desbridamiento enzimático con NexoBrid(R) en las primeras 24 horas. Posteriormente, llevamos a cabo tratamiento conservador con curas tópicas con Medihoney(R) Wound Gel. Recogimos todos los datos de calidad del desbridamiento, necesidad de desbridamiento quirúrgico, tiempo hasta epitelización completa, presencia de infección y necesidad de cirugía correctora de secuelas. Resultados. Tratamos 10 pacientes con quemaduras faciales de etiología diversa (llama, flash eléctrico, deflagración, escaldadura y química). El desbridamiento inicial fue completo en todos los pacientes. Se alcanzó la epitelización completa en una media de 13.88 días (10-20 días). Ningún paciente presentó infección clínicamente manifiesta ni precisó desbridamiento quirúrgico, cobertura mediante autoinjertos o cirugía de secuelas. Conclusiones. Nuestra experiencia preliminar indica que parece factible la aplicación de NexoBrid(R) y su combinación con Medihoney(R) para el tratamiento conservador de las quemaduras faciales (AU)


Background and Objective. Enzymatic debridement of burns has been studied for decades. In this theme, NexoBrid(R) (MediWound Ltd., Israel) is postulated as a promising alternative to classic surgical debridement of burns. Moreover, the antibacterial and healing properties of honey have been recently evaluated with good clinical results. This paper describes our preliminary experience with the use of NexoBrid(R) to treat burns in the facial area, followed by topical application of Medihoney(R) Wound Gel (Derma Sciences Ltd., USA). Methods. All patients received in our Burns Unit with dermal or subdermal facial burns affecting 2 or more aesthetic subunits were included in the study. Enzymatic debridement was performed with NexoBrid(R) in the first 24 hours. Subsequently, conservative management was carried on by topical cures with Medihoney(R) Wound Gel. Data about quality of debridement, the need for surgical debridement, time to complete epithelialization, presence of infection, and the need for corrective surgery of sequelae were collected. Results. Ten patients with facial burns of diverse etiology (flame, electric flash, deflagration, scald and chemical) were treated. The initial debridement was complete in all patients. Complete epithelialization was achived on an average of 13.88 days (10-20 days). No patient presented clinically apparent infection, and didn’t require surgical debridement, coverage by autografts, nor surgery of sequelae. Conclusions. Our preliminary results indicate that the application of NexoBrid® and its combination with Medihoney® for the conservative management of facial burns seems feasible (AU)


Assuntos
Humanos , Precursores Enzimáticos/uso terapêutico , Terapia Enzimática/métodos , Desbridamento/métodos , Queimaduras/terapia , Procedimentos de Cirurgia Plástica/métodos , Mel , Cicatrização
17.
Med. oral patol. oral cir. bucal (Internet) ; 20(6): e651-e656, nov. 2015. tab, ilus
Artigo em Inglês | IBECS | ID: ibc-144695

RESUMO

BACKGROUND: The aim of this study was to evaluate the effects of long and short term systemic usage of royal jelly on bone formation in the expanded maxillary suture in a rat model. MATERIAL AND METHODS: Twenty eight Wistar albino rats were randomly divided into 4 equal groups: Control (C); Only Expansion (OE), Royal Jelly (RJ) group, Royal Jelly was given to rats by oral gavage only during the expansion and retention period; Royal Jelly plus Nursery (RJN) group, Royal Jelly was given to rats by oral gavage during their nursery phase of 40 days and during the retention period. After the 5 day expansion period was completed, the rats underwent 12 days of mechanical retention. All rats were sacrificed in same time. Histological examination was performed to determine the number of osteoclasts, number of osteoblasts, number of capillaries, inflammatory cell infiltration, and new bone formation. RESULTS: New bone formation, number of osteoclasts, number of osteoblasts, and the number of capillaries in the expanded maxillary sutures were higher in the RJ and RJN groups than in the other groups. Statistical analysis also demonstrated that new bone formation and the number of osteoblasts was also highest in the RJN group. CONCLUSIONS: The systemic administration of Royal Jelly in conjunction with rapid maxillary expansion may increase the quality of regenerated bone


Assuntos
Animais , Feminino , Masculino , Ratos , Maxila/patologia , Maxila , Osteogênese/fisiologia , Modelos Animais , Mel , Oclusão Dentária , Osteoclastos/fisiologia , Reabsorção Óssea , Fenômenos Fisiológicos Dentários
18.
Nutr. hosp ; 32(4): 1432-1442, oct. 2015. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-143634

RESUMO

El presente artículo provee una revisión de literatura sobre el potencial biológico de la miel de Melipona beecheii. El objetivo es proyectar algunas tendencias en investigación sobre los aspectos nutracéuticos relacionados con los compuestos bioactivos presentes en la miel de esta especie de abeja sin aguijón, reconocida por sus características medicinales tradicionales, en la Península de Yucatán. Actualmente existe una evidencia sólida que demuestra que la miel de M. beecheii posee compuestos bioactivos tales como proteínas, flavonoides y polifenoles, con alta actividad antioxidante. La evidencia científica obtenida permite proponer a la miel de esta especie de abeja sin aguijón como alternativa para la obtención de compuestos bioactivos con actividad antioxidante en la Península de Yucatán, y ser propuesto como alimento natural para reducir algunos tipos de cáncer asociados al estrés oxidativo de las células fisiológicas del ser humano. Sin embargo, aún falta información que explique dicha actividad antioxidante; por lo tanto, de acuerdo con la literatura revisada, se ve la necesidad de abordar aspectos nutracéuticos y funcionales en correlación con los compuestos bioactivos presentes en esta miel de abeja (AU)


The present article provides a literature review about the biological potential of Melipona beecheii. The objective is to project some tendecies in research about nutraceutical aspects related to the bioactive compounds presents in the honey of this stingless bee species, known for its medicinal properties traditional, in the Yucatan Peninsula. Currently, there is strong evidence that M. beecheii honey has bioactive compounds such as proteins, flavonoids and polyphenols with high antioxidant activity. The scientific evidence allows to propose to the honey of stingless bee species as a potential alternative for the obtention of bioactive compounds with antioxidant activity in the Yucatan Peninsula and natural food being proposed to reduce some diseases associated with stress oxidative physiological human cells. However, there is still information that explains such antioxidant activity, therefore, according to the literature reviewed, sees the need to address nutraceuticals and functional aspects correlated with the bioactive compounds present in this honey bee (AU)


Assuntos
Humanos , Mel/análise , Antioxidantes/análise , Alimento Funcional/análise , Estresse Oxidativo/fisiologia , Suplementos Nutricionais/análise
19.
Allergol. immunopatol ; 43(5): 449-455, sept.-oct. 2015. tab, graf
Artigo em Inglês | IBECS | ID: ibc-141104

RESUMO

BACKGROUND: Honey is recommended for non-specific acute paediatric cough by the Australian guidelines. Current available randomised clinical trials evaluated the effects of a single evening dose of honey, but multiple doses outcomes have never been studied. OBJECTIVES: To evaluate the effects of wildflower honey, given for three subsequent evenings, on non-specific acute paediatric cough, compared to dextromethorphan (DM) and levodropropizine (LDP), which are the most prescribed over-the-counter (OTC) antitussives in Italy. METHODS: 134 children suffering from non-specific acute cough were randomised to receive for three subsequent evenings a mixture of milk (90 ml) and wildflower honey (10 ml) or a dose of DM or LDP adjusted for the specific age. The effectiveness was evaluated by a cough questionnaire answered by parents. Primary end-point efficacy was therapeutic success. The latter was defined as a decrease in cough questionnaire score greater than 50% after treatment compared with baseline values. RESULTS: Three children were excluded from the study, as their parents did not complete the questionnaire. Therapeutic success was achieved by 80% in the honey and milk group and 87% in OTC medication group (p = 0.25). CONCLUSIONS: Milk and honey mixture seems to be at least as effective as DM or LDP in non-specific acute cough in children. These results are in line with previous studies, which reported the health effects of honey on paediatric cough, even if placebo effect cannot be totally excluded


No disponible


Assuntos
Criança , Feminino , Humanos , Masculino , Tosse/tratamento farmacológico , Tosse/terapia , Dextrometorfano/uso terapêutico , Codeína/uso terapêutico , Mel , Leite , Antitussígenos/uso terapêutico , Resultado do Tratamento
20.
Metas enferm ; 17(9): 6-9, nov. 2014. tab
Artigo em Espanhol | IBECS | ID: ibc-131508

RESUMO

Las lesiones vasculares de las extremidades inferiores constituyen un problema de salud con importantes consecuencias socioeconómicas y sanitarias, no existe un tratamiento único y efectivo para su curación. El propósito de este trabajo es contribuir al conocimiento existente sobre el uso tópico de la miel para la curación de este tipo de lesiones y su aplicación en la práctica clínica. Se presenta el caso clínico de A.M.L., de 80 años de edad, con úlcera venosa en miembro inferior derecho de dos meses de evolución. Diagnóstico enfermero: deterioro de la integridad cutánea manifestado por úlcera en cara externa tibial de tobillo derecho relacionado con insuficiencia venosa de miembros inferiores. Resultado esperado: cicatrización completa de la úlcera en seis meses (NOC: Curación de la herida: por segunda intención). Intervención enfermera: se establece el tratamiento de cura de la herida con la aplicación de miel sobre ella tres veces por semana (NIC: Cuidados de la herida).Tras una rápida cicatrización inicial de la cavidad de la herida y eliminación de los pequeños esfacelos del lecho, la lesión se complica y agrava y se establece cura con apósito hidrocoloide de silicona y compresión tres veces por semana. Se consiguió la completa cicatrización de la herida en tres meses y medio aproximadamente desde el inicio de la segunda intervención. Son necesarios más estudios para determinar el uso seguro y eficaz de la miel como tratamiento de las úlceras venosas en extremidades inferiores


Vascular lesions in lower limbs represent a health problem with major socioeconomic and healthcare consequences; there is not an unique and effective treatment for them. The purpose of this article is to contribute to the existing knowledge about the topical use of honey for treating this type of lesions, and its application on clinical practice. The clinical case of A.M.L. is presented: an 80-year-old patient with a venous ulcer in the right lower limb, with two months of evolution. Nursing diagnosis: deterioration of cutaneous integrity caused by an ulcer in the external face of the right ankle tibia, associated with venous insufficiency in lower limbs. Expected result: complete scarring of the ulcer within six months (NOC: Wound healing: by second intention). Nursing intervention: The treatment for wound healing is established by applying honey on it three times per week (NIC: Wound care). After a fast initial scarring of the wound cavity, and removal of the small sloughing in the wound bed, the lesion gets complicated and worsens, and healing is established with hydrocolloid dressing with silicone and compression three times per week. Complete wound scarring was achieved at approximately three months and a half since the initiation of the second intervention. More studies are required in order to establish the safe and effective use of honey as treatment for venous ulcers in lower limbs


Assuntos
Humanos , Feminino , Idoso de 80 Anos ou mais , Úlcera da Perna/tratamento farmacológico , Mel , Cicatrização , Úlcera Varicosa/tratamento farmacológico
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