Efectos posturográficos de la maniobra de Epley en pacientes con vértigo posicional paroxístico del canal posterior / Posturographic effects of the Epley maneuver on patients with benign paroxysmal positional vertigo of the posterior canal

Resumen Introducción: El vértigo posicional paroxístico benigno (VPPB) es la afección periférica más común en las enfermedades otoneurológicas. Con el reposicionamiento de partículas se busca eliminar el vértigo y sus síntomas asociados como lo son el mareo residual y la inestabilidad. Objetivo: Determinar si la maniobra de reposicionamiento de Epley (MRE) produce una modificación significativa del control postural (CP) en aquellos pacientes con VPPB de canal semicircular posterior (VPPB-CSC-P). Material y Método: Se realizó un estudio descriptivo prospectivo en una muestra de 21 pacientes con diagnóstico de VPPB-CSC-P. Comparamos el desplazamiento, la velocidad y el área del centro de presión (CoP) antes y después de la MRE. Resultados: La velocidad y el área de la CoP estudiada por posturografía computarizada muestra una disminución significativa en sus valores después de la MRE, mientras que el desplazamiento de la CoP se mantuvo sin cambios. Conclusión: La MRE ejecutada en pacientes con VPPB-CSC-P produce una modulación en el control de la CoP, demostrada por la disminución de la velocidad y el área de desplazamiento de la CoP. El éxito de la MRE produce modulación del CP.

Abstract Introduction: Benign paroxysmal positional vertigo (BPPV) is the most common peripheral condition in otoneurologic diseases. With the repositioning of particles, the aim is to eliminate vertigo and its associated symptoms, such as residual dizziness and instability. Aim: To determine if the Epley repositioning maneuver (ERM) produces a significant modification of postural control (PC) in those patients with posterior semicircular canal BPPV (BPPV-CSC-P). Material and Method: A prospective descriptive study was carried out in a sample of 21 patients diagnosed with BPPV-CSC-P. We compared the displacement, velocity, and area of the center of pressure (CoP) before and after the Epley repositioning maneuver. Results: The velocity and the area of the CoP studied by computed posturography show a significant decrease in its values after the MRE, while the CoP shift remained unchanged. Conclusion: ERM performed in patients with BPPV-CSC-P produces an improvement in the control of the CoP, demonstrated by the decrease in the speed and the area of movement of the CoP. The success of the MRE produces modulation of the PC.

Factores asociados a falla terapéutica con maniobras de reposición canalicular en pacientes con diagnóstico de vértigo posicional paroxístico benigno en la Clínica de Otorrinolaringología de Antioquia, Medellín, Colombia / Factors associated with therapeutic failure with canalicular repositioning maneuvers in patients diagnosed with benign paroxysmal positional vertigo at Antioquia Otorhinolaryngology Clinic, Medellin, Colombia"

Introducción: múltiples factores se han relacionado con el desarrollo de la recurrencia del vértigo posicional paroxístico benigno (VPPB). Objetivo: determinar la asociación entre la falla terapéutica de las maniobras de reposición canalicular (MRC) y las variables sociodemográficas y clínicas en los pacientes con diagnóstico de VPPB. Diseño: estudio observacional de cohorte retrospectiva. Materiales y métodos: revisión de historias clínicas de la consulta de vértigo de la Clínica Orlant, Medellín, Colombia. Resultados: se incluyeron 41 pacientes con diagnóstico de VPPB a quienes se les realizó MRC y seguimiento clínico entre 1 y 8 semanas. El 90,2 % eran de sexo femenino, con una mediana de edad de 58 (±183) años; se encontró uso de vestibulosupresores en un 68,3 %, y es la betahistina el más consumido (43,9 %). El 51,2 % de pacientes presentaron falla terapéutica y se identificó una asociación con el número total de MRC realizadas y el uso de vibrador mastoideo (p < 0,001), teniendo en cuenta que los pacientes mejoraron clínicamente al final del seguimiento con una media de 77 % (p < 0,001). No se encontraron asociaciones estadísticamente significativas con el resto de variables. Conclusión: no hubo asociación entre la falla terapéutica y las variables estudiadas, excepto número de MRC, el uso del vibrador mastoideo y la mejoría clínica final, posiblemente porque el vibrador mastoideo se aplica a los pacientes en quienes hay persistencia de síntomas y signos con las maniobras desencadenantes, y por factores fisiopatológicos no esclarecidos; con esto finalmente se logra una mejoría clínica con más de dos MRC

Introduction: Multiple factors have been related to the development of recurrence of benign paroxysmal positional vertigo (BPPV). Objective: To determine the association between therapeutic failure of canalicular repositioning maneuvers (CRM) with sociodemographic and clinical variables in patients with a diagnosis of BPPV. Design: Observational retrospective cohort study. Materials and methods: Review of medical records of the vertigo clinic of the Orlant Clinic, Medellín - Colombia. Results: 41 patients with a diagnosis of BPPV who underwent CRM and clinical follow-up between 1 and 8 weeks were included. 90.2% were female, with a median age of 58 (± 18.3) years, use of vestibulosuppressants was found in 68.3%, betahistine being the most consumed (43.9%). 51.2% of patients presented therapeutic failure, identifying an association with the total number of CRMs performed and the use of a mastoid vibrator with (p < 0.001), taking into account that the patients improved clinically at the end of follow-up with a mean of 77% (p < 0.001). No statistically significant associations were found with the rest of the variables. Conclusion: There was no association between therapeutic failure and the variables studied except number of CRM, use of the mastoid vibrator and final clinical improvement, possibly because the mastoid vibrator is applied to patients in whom there are persistence of symptoms and signs with the triggering maneuvers for unclear pathophysiological factors, finally achieving clinical improvement with more than two CRMs.

Betahistine alleviates benign paroxysmal positional vertigo (BPPV) through inducing production of multiple CTRP family members and activating the ERK1/2-AKT/PPARy pathway

BACKGROUND: Betahistine is a clinical medication for the treatment of benign paroxysmal positional vertigo (BPPV). Otolin, a secreted glycoprotein with a C-terminal globular domain homologous to the immune complement C1q, has been identified as a biomarker for BPPV. However, the role of complement C1q/TNF-related proteins (CTRPs) with a C-terminal globular domain in BPPV is unclear, so we explored the change of CTRPs in betahistine treated BPPV. METHODS: We treated BPPV patients with Betahistine (12 mg/time, 3 times/day) for 4 weeks and observed the clinical efficacy and the expression of CTRP family members in BPPV patients. Then, we constructed a vertigo mice model of vestibular dysfunction with gentamicin (150 mg/Kg) and a BPPV model of Slc26a4loop/loop mutant mice. Adenoviral vectors for CTRP expression vector and small interfering RNA were injected via the intratympanic injection into mice and detected the expression of CTRP family members, phosphorylation levels of ERK and AKT and the expression of PPARγ. In addition, we treated mice of vestibular dysfunction with Betahistine (10 mg/Kg) and/or ERK inhibitor of SCH772984 (12 mg/Kg) and/or and PPARγ antagonist GW9662 (1 mg/Kg) for 15 days, and evaluated the accuracy of air righting reflex, the time of contact righting reflex and the scores of head tilt and swimming behavior. RESULTS: After treatment with Betahistine, the residual dizziness duration and the score of the evaluation were reduced, and the expression of CTRP1, 3, 6, 9 and 12 were significantly increased in BPPV patients. We also found that Betahistine improved the accuracy of air righting reflex, reduced the time of contact righting reflex and the scores of head tilt and swimming behavior in gentamicin-treated mice and Slc26a4loop/loop mutant mice. The expression levels of CTRP1, 3, 6, 9 and 12, phosphorylation levels of ERK and AKT, and PPARγ expression were significantly increased, and the scores of head tilt and swimming behavior were decreased in vestibular dysfunction mice with overexpression of CTRPs. Silencing CTRPs has the opposite effect. SCH772984 reversed the effect of Betahistine in mice with vestibular dysfunction. CONCLUSION: Betahistine alleviates BPPV through inducing production of multiple CTRP family members and activating the ERK1/2-AKT/PPARy pathway.

O efeito dos exercícios vestibulares na qualidade de vida e na intensidade de tontura de idosos com hipofunção vestibular unilateral / The effect of vestibular exercises on quality of life and intensity of dizziness in the elderly with unilateral vestibular hypofunction

Objetivo: analisar o efeito dos exercícios vestibulares na qualidade de vida e na intensidade de tontura de idosos com hipofunção vestibular unilateral. Método: participaram do estudo idosos com sintomas de tontura. A qualidade de vida foi avaliada pela versão brasileira do Dizziness Handicap Inventory e a intensidade de tontura por uma escala visual analógica. Para cada participante foi desenvolvido um protocolo de exercícios personalizado de acordo com seus sintomas. Utilizou-se o teste t-Student para avaliar a intensidade de tontura e, para comparar os resultados da qualidade de vida, utilizou-se o teste não-paramétrico de Wilcoxon (p<0,05). O teste de correlação de Pearson averiguou associações entre intensidade de tontura e qualidade de vida. Resultados: verificou-se diferença estatisticamente significativa para a intensidade de tontura (p<0,0007) e para os domínios físico (p<0,0009), funcional (p<0,0009), emocional (p<0,03) e total (p<0,001) da qualidade de vida dos idosos com hipofunção vestibular unilateral. Referente à correlação, quanto mais intenso o sintoma de tontura, maiores foram os prejuízos na qualidade de vida. Conclusão: os exercícios vestibulares contribuíram para a diminuição da intensidade da tontura dos idosos com hipofunção vestibular unilateral e, consequentemente, para melhora da qualidade de vida e seus respectivos domínios. (AU)

Objective: to analyze vestibular exercise in quality of life and intensity of dizziness in the elderly with unilateral vestibular hypofunction. Method: elderly with symptoms of dizziness participated in the study. The quality of life was assessed by the Dizziness Handicap Inventory and the intensity of dizziness by a visual analogical scale. For each participant a personalized treatment protocol was developed according to their symptoms. The t-Student test was used to assess the intensity of dizziness and Wilcoxon's nonparametric test to analyze the quality of life (p <0.05). The Pearson correlation test was used to verify the associations between intensity of dizziness and quality of life. Results: a statistically significant difference was observed for the intensity of dizziness (p<0.0007) and to the physical (p<0.0009), functional (p<0.0009), emotional (p<0.03) domains and total (p<0.001) of the quality of life of the elderly with unilateral vestibular hypofunction. Concerning the correlation, the more intense the symptom of dizziness, the greater the impairment in quality of life. Conclusion: the vestibular exercises contributed to decrease the intensity of dizziness in the elderly with unilateral vestibular hypofunction and, consequently, to improve the quality of life and their respective domains. (AU)

Calidad de vida en personas que padecen vértigo posicional paroxístico benigno / Quality of life in people suffering from benign paroxysmal positional vertigo

La presente investigación da a conocer el impacto de la maniobra de reposición Epley en la calidad de vida de las personas que padecen de vértigo postural paroxístico benigno, de 35 años y más. Para el conocimiento de la calidad de vida se aplicó un test de autopercepción llamado Dizziness Handicap Inventory (DHI), el cual se tomó antes y después de la maniobra de Epley, en un periodo de tres semanas, con el fin de verificar si la calidad de vida variaba en función al tratamiento. La Metodología en la investigación fue descriptiva- comparativa, ya que, busca establecer la diferencia de las personas pre y post maniobra de reposición, la dimensión fue longitudinal y la muestra fueron 12 personas escogidas de forma no aleatoria. En relación a los resultados se observa que existe una mejoría en la calidad de vida a la hora de comparar los resultados antes y después del tratamiento.

This research reveals the impact of the Epley replacement jaw on people suffering from benign paroxysmal postural vertigo, 35 years of age and older. To know the quality of life, a self-perception test called Dizziness Handicap Inventory (DHI) was applied, which must be performed before and after the Epley maneuver, in order to verify whether the quality of life varied or not depending on the treatment. The methodology in the research was descriptive-comparative, since it seeks to establish the difference of the people before and after the replacement maneuver, the dimension was longitudinal and the sample was 12 people chosen in a non-random way. Regarding the results, it is observed that there is an improvement in the quality of life when comparing the results before and after treatment

Efectividad de los ejercicios de Brandt-Daroff en pacientes con vértigo posicional paroxístico benigno / Effectiveness of the Brandt-Daroff Exercises in Patients with Benign Paroxysmal Positional Vertigo

El vértigo posicional paroxístico benigno se caracteriza por episodios breves pero intensos de vértigo con los cambios de postura, en su tratamiento pueden utilizarse ejercicios específicos. Objetivo: Evaluar la efectividad de los ejercicios de Brandt-Daroff en el tratamiento del vértigo posicional paroxístico benigno y su relación con los grupos de edades y sexo. Métodos: Se aplicó un método descriptivo, con una muestra de 62 pacientes adultos que presentaban diagnóstico de vértigo paroxístico posicional benigno. Se utilizó la escala dicotómica con presencia o ausencia de vértigo, al inicio y final del tratamiento con estos ejercicios. Se analizaron las variables: edad, sexo y mejoría clínica de la enfermedad. Para el análisis estadístico se utilizó la Prueba de homogeneidad λ2 con un nivel de significación de ά 0,05. Resultados: Se observó evolución favorable para el tratamiento de este trastorno mediante los ejercicios de Brandt-Daroff con el 87,09 por ciento en la eliminación del vértigo a las 7 sesiones de tratamiento, un 90 por ciento de efectividad en edades de 25 a 59 años y el 76,19 por ciento del sexo femenino, de ellas el 91,66 por ciento no presentó vértigos a final del tratamiento. Conclusiones: Se señala la efectividad de los ejercicios de Brandt-Daroff en el tratamiento del vértigo paroxístico posicional benigno con diferencias estadísticamente significativas en comparación con el tratamiento convencional. Mayor efectividad en edades de 25 a 59 años y el predominio del sexo femenino(AU)

Benign paroxysmal positional vertigo is characterized by brief but intense episodes of vertigo with changes in posture. Specific exercises can be used for its treatment. Objective: To evaluate the effectiveness of Brandt-Daroff exercises in the treatment of benign paroxysmal positional vertigo and its relationship with age and sex groups. Methods: A descriptive method was applied, with a sample of 62 adult patients who had a diagnosis of benign positional paroxysmal vertigo. The dichotomous scale with presence or absence of vertigo was used at the beginning and at the end of treatment with these exercises. The variables analyzed were age, sex, and clinical improvement of the disease. For statistical analysis, the chi-square homogeneity test was used with a significance level of 0.05. Results: A favorable evolution was observed for the treatment of this disorder by means of the Brandt-Daroff exercises, with 87.09 percent in the elimination of vertigo after seven treatment sessions, 90 percent effective in ages 25-59 years, and 76.19 percent corresponding to the female sex, of which 91.66 percent did not present vertigo at the end of treatment. Conclusions: The effectiveness of the Brandt-Daroff exercises is highlighted for the treatment of benign positional paroxysmal vertigo, with statistically significant differences compared to conventional treatment. Greater effectiveness in ages 25-59 years and the predominance of the female sex(AU)

Mareo residual, una condición clínica frecuente posterior a maniobra de reposición exitosa en vértigo posicional paroxístico benigno: una revisión / Residual dizziness, a frequent clinical condition following successful repositioning maneuver for benign paroxysmal positional vertigo: a review

El vértigo posicional paroxístico benigno (VPPB) es reconocido como la principal causa de vértigo de origen periférico en adultos, ya que, si bien la etiología del VPPB aún no se ha demostrado plenamente y se clasifica como la mayoría de los casos, se puede identificar el desprendimiento de otolitos y su desplazamiento en uno de los tres canales semicirculares. Una anamnesis cuidadosa puede abordar el diagnóstico clínico del VPPB, pero la confirmación se obtendrá por medio de maniobras de diagnóstico especificas de acuerdo a cuál de los canales está involucrado. Este trastorno altera la capacidad de llevar a cabo actividades de la vida cotidiana que determinan un aumento significativo en el riesgo de caídas y las consiguientes lesiones. La mayoría de los pacientes se recuperan después del tratamiento, sin embargo, hasta dos tercios de éstos pueden percibir inestabilidad prolongada, aturdimiento y malestar definidos como mareo residual. Esta sintomatología residual después de la resolución del VPPB es variable entre los pacientes, siendo el tiempo de duración de los síntomas residuales de aproximadamente de 1 a 3 semanas, existiendo algunos pacientes que pueden recuperarse más tardíamente. En esta revisión analizaremos el mareo residual, describiendo su expresión clínica, diagnóstica, fisiopatológica y tratamientos actuales de esta entidad clínica.

Benign paroxysmal positional vertigo (BPPV) is recognized as the main cause of peripheral vertigo in adults, although the etiology of BPPV has not yet been fully demonstrated and is classified as idiopathicin most cases, detachment of otoliths and their displacement in one of the three semicircular canals can be identifie. A careful history can address the clinical diagnosis of BPPV, but confirmation will be obtained through specific diagnostic maneuvers according to which canal is involved. This disorder alters the ability to carry out activities of daily living that determine a significant increase in the risk of falls and consequent injuries. Most patients recover after treatment, however, up to two thirds of these patients may perceive prolonged instability, dizziness and discomfort defined as residual dizziness. This residual symptomatology following BPPV resolution is variable among patients, the duration of residual symptoms can last 1 to 3 weeks, with some patients may recover later on. In this review, we will analyze residual dizziness, describing its clinical presentation, diagnosis, pathophysiology and current treatments of this clinical entity.

Vértigo posicional paroxístico benigno: factores de riesgo asociados y eficacia de las maniobras de reposición / Benign paroxysmal positional vertigo: associated risk factors and efficacy of particle repositioning maneuvers

INTRODUCCIÓN: El vértigo posicional paroxístico benigno (VPPB) es el vértigo periférico más frecuente. El tratamiento depende del compromiso de los canales semicirculares (CSC) y/o cúpulas, y consiste en maniobras de reposición de partículas. OBJETIVO: Evaluar los factores de riesgo asociados al VPPB en pacientes atendidos en el Servicio de Otorrinolaringología de la Red de Salud UC Christus. Evaluar la tasa de éxito de las maniobras de reposición. MATERIAL Y MÉTODO: Estudio retrospectivo. Se revisaron casos de VPPB con indicación de maniobras de reposición durante los años 2016-2017. Se obtuvo información demográfica, antecedentes médicos, la maniobra realizada y su éxito. Se evaluaron comorbilidades y temporada del año. RESULTADOS: Se incluyeron 195 consultas, realizándose 293 maniobras. La mayoría de los pacientes fueron mujeres (74%) con edad promedio de 63 años. Comorbilidades más frecuentes fueron hipertensión, dislipidemia y diabetes mellitus. El 20% presentó una hipofunción vestibular concomitante, 23% presentó antecedentes de VPPB y 8% compromiso bilateral. Canalolitiasis del CSC posterior fue predominante (90%). En el 77,3% se resuelve el caso con una maniobra. Los casos fueron más frecuentes en primavera y otoño. CONCLUSIONES: El VPPB fue más frecuente en mujeres, con una edad promedio de 63 años. La mayoría presentó canalolitiasis unilateral lográndose resolución con una maniobra de reposición.

INTRODUCTION: Benign paroxysmal positional vertigo (BPPV) is the most common cause of peripheral vertigo. The treatment depends on the semicircular canal (SCC) and/or cupula involved and consists of particle repositioning maneuvers. AIM: Analyze risk factors associated with BPPV for patients seen at the otorhinolaryngology department of the UC Christus health center. Evaluate the success rate of the repositioning maneuvers. MATERIAL AND METHODS: Retrospective study. All cases of BPPV for which a repositioning maneuver was prescribed during the years 2016-2017 were reviewed. Data obtained includes demographics, medical history, maneuver performed, and its success rate. Comorbidities and seasonality were evaluated. RESULTS: 195 cases were included; with 293 maneuvers. The majority were women (74%), and the average age was 63 years. Common comorbidities were hypertension, dyslipidemia and diabetes mellitus. Concurrently, 20% had unilateral vestibular hypofunction, 23% had a history of BPPV, and 8% had bilateral involvement. Posterior SCC canalithiasis was most common (90%). In 77.3%, the case was resolved with one maneuver. Cases were most frequent in the spring and autumn season. CONCLUSION: BPPV was more common in women with an average age of 63 years. The majority of patients presented with unilateral canalithiasis obtaining a complete recovery with a single maneuver.

Subjective benign paroxysmal positional vertigo in patients with osteoporosis or migraine / Vertigem posicional paroxística benigna subjetiva em pacientes com osteoporose ou migrânea

Abstract Introduction Subjective benign paroxysmal positional vertigo is a form of benign paroxysmal positional vertigo in which during the diagnostic positional maneuvers patients only present vertigo symptoms with no nystagmus. Objective To study the characteristics of subjects with subjective benign paroxysmal positional vertigo. Methods Prospective multicenter case-control study. All patients presenting with vertigo in the Dix-Hallpike test that presented to the participating hospitals were included. The patients were separated into two groups depending on whether nystagmus was present or not. An Epley Maneuver of the affected side was performed. In the follow-up visit, patients were checked to see if nystagmus and vertigo were present. Both groups of patients were compared to assess the success rate of the Epley maneuver and also to compare the presence of 19 variables. Results 259 patients were recruited, of which 64 belonged to the subjective group. Nystagmus was eliminated in 67.2% of the patients with benign paroxysmal positional vertigo. 89.1% of the patients with subjective benign paroxysmal positional vertigo remained unaffected by nystagmus, thus showing a significant difference (p = 0.001). Osteoporosis and migraine were the variables which reached the closest to the significance level. In those patients who were taking vestibular suppressors, the percentage of subjective benign paroxysmal positional vertigo was not significantly higher. Conclusions Subjective benign paroxysmal positional vertigo should be treated using the Epley maneuver. More studies are needed to establish a relationship between osteoporosis, migraine and subjective benign paroxysmal positional vertigo. The use of vestibular suppressants does not affect the detection of nystagmus.

Resumo Introdução A vertigem posicional paroxística benigna subjetiva é um tipo de vertigem posicional paroxística benigna na qual, durante as manobras posicionais diagnósticas, os pacientes apresentam apenas sintomas vertiginosos sem nistagmo. Objetivo Estudar as características de indivíduos com vertigem posicional paroxística benigna subjetiva. Método Estudo prospectivo multicêntrico de caso-controle. Foram incluídos todos os pacientes com vertigem no teste de Dix-Hallpike, que se apresentaram nos hospitais participantes. Os pacientes foram separados em dois grupos, dependeu da presença ou não do nistagmo. Uma manobra de Epley foi realizada no lado afetado. Na consulta de seguimento, os pacientes foram avaliados para verificar a presença ou não do nistagmo e da vertigem. Ambos os grupos de pacientes foram comparados para avaliar a taxa de sucesso da manobra de Epley e também para comparar a presença de 19 variáveis. Resultados Foram recrutados 259 pacientes, dos quais 64 pertenciam ao grupo subjetivo. O nistagmo foi eliminado em 67,2% dos pacientes com vertigem posicional paroxística benigna. Em 89,1% dos casos, os pacientes com vertigem posicional paroxística benigna subjetiva mantiveram-se não afetados pelo nistagmo, mostraram uma diferença significativa (p = 0,001). Osteoporose e enxaqueca foram as variáveis que atingiram o nível mais próximo ao de significância. Nos pacientes que tomavam supressores vestibulares, a porcentagem de vertigem posicional paroxística benigna subjetiva não foi significativamente maior. Conclusões A vertigem posicional paroxística benigna subjetiva deve ser tratada com a manobra de Epley. Mais estudos são necessários para estabelecer uma relação entre osteoporose, enxaqueca e vertigem posicional paroxística benigna subjetiva. O uso de supressores vestibulares não afeta a detecção do nistagmo.

Déficits vestibulares e vertigem posicional paroxística benigna em adultos jovens assintomáticos: um estudo transversa / Vestibular deficits and benign paroxysmal positional vertigo in young asymptomatic adults: a transversal study

Introdução: O equilíbrio corporal pode ser afetado por déficits visuais, proprioceptivos e/ou vestibulares centrais ou periféricas. Dentre as afecções vestibulares periféricos, a Vertigem Postural Paroxística Benigna apresenta grande interesse em pesquisas que buscam responder suas apresentações clínicas em adultos e sua associação com a integralidade dos demais sistemas corporais. Objetivo: Analisar as respostas de adultos jovens assintomáticos submetidos à semiologia do sistema vestibular. Metodologia: Estudo quantitativo, transversal analítico e descritivo, onde foram utilizados os testes de equilíbrio estático, dinâmico e a manobra de DixHallpike, com amostra de 30 voluntários assintomáticos recrutados em uma instituição de ensino superior do município de Parnaíba/PI. Resultados: O teste de apoio unipodal (1,87 ± 0,346) foi negativo (p < 0,001) e no teste de Fukuda (1,20 ± 0,407) grande parte tiveram resultados positivos (p < 0,001). Os testes de Romberg (2,00 ± 0,000), Romberg-Barré (1,50 ± 0,509) e Babinski-Weil (1,37 ± 0,490) não foram significantes (p = 0,001). Para a Manobra de Dix-Hallpike observamos que os movimentos de sedestação para decúbito dorsal esquerdo e de decúbito dorsal para sedestação direito e esquerdo foram significativos (p < 0,001). Conclusão: Os adultos jovens assintomáticos podem apresentar resultados positivos em teste de equilíbrio e sintomas na manobra de Dix-Hallpike, confirmando a Vertigem Postural Paroxística Benigna.(AU)

Introduction: Body balance can be affected by visual deficits, proprioceptive and/or central or peripheral vestibular. Among the peripheral vestibular disorders, the Benign Paroxysmal Positional Vertigo presents great interest in research seeking to answer clinical presentations in adults and its association with the completion of other body systems. Objective: To analyze the responses of asymptomatic young adults with symptoms of the vestibular system. Methods: This was a quantitative, descriptive analytical cross-sectional, where we used the tests of static balance, dynamic and Dix-Hallpike, with a sample of 30 asymptomatic volunteers recruited in a higher education institution in the city of Parnaíba/PI, Brazil. Results: The one-leg supporting roll 1.87 ± 0.346) was negative (p < 0.001) and the test Fukuda (1.20 ± 0.407) were largely positive (p < 0.001). The Romberg test (2.00 ± 0.000) Romberg-Barré (1.50 ± 0.509) and Babinski-Weil (1,37 ± 0.490) were not significant (p = 0.001). For the Maneuver Dix-Hallpike we observed that the movements of the sitting position to the left supine and supine to right and left sedestation were significant (p < 0.001). Conclusion: Asymptomatic young adults may have positive results on balancing test and symptoms in the Dix-Hallpike, confirming the Benign Paroxysmal Positional Vertigo. (AU)

Retraso en la mejoría del vértigo posicional paroxístico benigno asociado al consumo de vestibulosupresores / Delay on the improvement of Benign Paroxysmal Positional Vertigo associated with the use of vestibular suppressants

Introducción: el vértigo posicional paroxístico benigno (VPPB) constituye un motivo de consulta común. A pesar de contar con un manejo sencillo con la realización de maniobras los pacientes son tratados de una manera subóptima; secundario a esto, se observa la administración de medicamentos con los cuales no se logra determinar la causa central de su queja, aumentando el número de consultas. Objetivos: explorar la asociación del uso de vestibulosupresores con el tiempo de diagnóstico y recuperación de los pacientes con VPPB. Diseño: estudio observacional, descriptivo, retrospectivo. Metodología: se incluyeron pacientes con diagnóstico de VPPB; fueron distribuidos en dos grupos según el antecedente de consumo de vestibulosupresores en los últimos 3 meses, con lo cual se evaluó el tiempo de diagnóstico y mejoría, entre octubre 1 de 2010 y mayo 31 de 2017. Resultados: se reclutaron 109 pacientes, 18 hombres y 91 mujeres. Pacientes con uso reciente de vestibulosupresores 91 y sin uso 18. El diagnóstico en el primer grupo requirió varias consultas, el segundo grupo requirió solo una consulta. El tiempo de evolución en días del primer grupo comparado con el segundo fue de 76 y 47 días, respectivamente. El tiempo que pasó entre el diagnóstico y la mejoría sintomática completa fue de 41 y 31 días, respectivamente. Conclusiones: el antecedente de consumo de vestibulosupresoresvs. no consumo, genera un aumento en las consultas para llegar al diagnóstico de VPPB, mayor tiempo de evolución clínica, entre el diagnóstico y la mejoría de los síntomas, sin diferencias estadísticamente significativas.

Introduction: Benign Paroxysmal Positional Vertigo (BPPV) constitutes a common chief complaint during consultation. Despite having a simple management with the performance of maneuvers, patients are treated in a suboptimal manner; secondary to this, it is observed that the administration of medications makes it difficult to determine the cause of their chief complaint, increasing the number of consultations. Objectives: To explore the association of the use of vestibular suppressants with the time of diagnosis and recovery in patients with BPPV. Design: Observational, descriptive, retrospective study. Methods: It included patients with a diagnosis of BPPV; Patients were distributed into two groups based on the history of the use of vestibular suppressant in the previous 3 months. The time of diagnosis and improvement for said patients were evaluated between October 1 of 2010 and May 31 of 2017. Results: 109 patients were enrolled, 18 males and 91 females. Patients with recent use of vestibular suppressants were 91, and those with no history of use 18. Diagnosis in the first group required several consultations while only one was required in the second group. Duration of illness in days for the first group compared to the second was 76 and 47 days respectively, and the time between clinical diagnosis and complete symptomatic improvement was 41 and 31 days respectively. Conclusions: history of vestibular suppressant use, is associated with an increased frequency of consultations reaching a diagnosis of BPPV, greater duration of clinical condition and greater delay between the time of diagnosis and time of clinical improvement. However, this association was not found to be statistically significant.

Identification of factors related to cases of benign paroxysmal positional vertigo refractory to canalicular repositioning maneuvers and evaluation of the need for magnetic resonance imaging in their management: retrospective analysis of a series of 176 cases

Introduction: Benign paroxysmal positional vertigo (BPPV) is the most common form of peripheral vertigo, and, in most cases, it presents a favorable prognosis. The treatment is based on a series of specific canalicular repositioningmaneuvers that offer an efficacy close to 100%. Despite this, there are cases that are refractory to treatment, with the persistence of the vertigo symptoms. Objectives: The objective of the present paper is to analyze the factors associated with an increased risk of refractory BPPV and the importance of nuclear magnetic resonance in the study of these patients. Methods: We retrospectively reviewed the cases of 176 patients diagnosed with BPPV in our center.We divided them into two groups: responders and non-responders to the treatment, and analyzed the possible risk factors associated with a higher risk of refractory vertigo. Fischer exact test was used. Results: We found 11 cases refractory to treatment; all of them underwent magnetic resonance imaging (MRI) with gadoliniumaccording to our protocol. Of these, four had an otoneurologic background or pathology, and two other patients presented a multicanal involvement. The difference between the two groups was statistically significant (p < 0.05). Conclusion: Otoneurologic background and multicanal involvement were associated with a higher risk of refractory BPPV. When dealing with a BPPV with persistent symptomatology/nystagmus or with early relapse after an initial improvement, other entities that enter into the differential diagnosis must always be considered. We consider it essential to perform an MRI with gadolinium to rule out cases of BPPV that have a central cause (AU)

Aspectos clínicos da vertigem posicional paroxística benigna em pacientes acompanhados no ambulatório de otoneurologia em um hospital terciário / Clinical aspects of benigin paroxystic positional vertigin in patients followed at the otoneurology outlet in a tertiary hospital

RESUMO Introdução: A vertigem posicional paroxística benigna (VPPB) é uma síndrome clínica caracterizada por episódios breves e recorrentes de vertigem provocada por certas posições da cabeça em relação à gravidade. A VPPB é a causa mais comum de vertigem secundária a uma lesão vestibular periférica. Seu tratamento baseia-se principalmente nas manobras de reposição canalicular, e devido a simplicidade dessas manobras, seu caráter nãoinvasivo, boa aceitação pelo paciente e por serem, geralmente, livres de complicações, as manobras de reposicionamento de otólitos se popularizaram. Objetivos Avaliar pacientes com vertigem posicional paroxística benigna quanto ao gênero, idade, comorbidades, tipo e localização da lesão, dados evolutivos recorrência, fatores desencadeantes e sintomas concomitantes. Métodos: Este estudo utilizou revisão de prontuários de pacientes acompanhados em hospital de nível terciário no período de janeiro de 2018 a janeiro de 2019, portadores de vertigem posicional paroxística benigno. Resultados: Verificou-se que os pacientes acompanhados no nosso serviço têm perfil epidemiológico e clínico semelhantes aos trabalhos publicados, e que dados que divergem da literatura deve-se ao fator que tal caraterísticas não foi informada pelo paciente ou não foi relatado em prontuário. Conclusão: A VPPB é mais prevalente no sexo feminino, a média de idade foi 59,2 anos, a comorbidade mais encontrada foi a hipertensão arterial sistêmica, a maioria dos casos ocorrem com vertigem e nistagmo de posicionamento por ductolitíase do canal posterior direito. A média de manobras foram 2,4 para os casos com ductolitíase e 6,7 para os casos com cupulolitíase. Três pacientes apresentaram recorrência da crise de vertigem em menos de três meses. O principal fator provocador da vertigem foi girar a cabeça e a náusea foi a manifestação neurovegetativa mais relatada pelos pacientes desse estudo. Palavras-chave: Vertigem, Vertigem posicional paroxística benigna, Doenças vestibulares.

Physical Therapy for Posterior and Horizontal Canal Benign Paroxysmal Positional Vertigo: Long-term Effect and Recurrence: A Systematic Review

Abstract Introduction Benign paroxysmal positional vertigo (BPPV) is the most common cause of vertigo, and it is characterized by episodes of vertigo roundabout when the head is moved. A systematic review was performed using the most important scientific databases. This review included studies published in English in the last ten years, performed in adults, with emphasis on the diagnosis and treatment of BPPV. Objective To investigate the long-term effectiveness of vestibular rehabilitation (VR) in patients with BPPV and the rate of recurrence of symptoms. Data Synthesis A total of 38 studies were identified, of which only 12 met the inclusion criteria. The majority of the studies stated that VR is effective in decreasing the symptoms, with a short-term efficacy of 84.7%, and 89.2% in the long term in the reviewed studies. Conclusion Valuable studies show the beneficial effects of the maneuvers for the treatment of BPPV and their long-term effectiveness. This strengthens the conclusion that this treatment is effective in resolving symptoms and decreasing recurrences.

Enfoque del paciente con vértigo / Approach to patients with vertigo

El vértigo es definido como la sensación de movimiento ilusorio del cuerpo o de los objetos que le rodean. Es una de las causas más comunes de consulta en los departamentos de emergencia, y 2 a 3% de la población mundial consulta anualmente por este síntoma. De acuerdo al compromiso vestibular en el oído interno o en el sistema nervioso central o ambos, puede clasificarse en vértigo periférico, central o de origen mixto, siendo la principal causa del periférico el vértigo posicional paroxístico benigno. La valoración semiológica y anamnesis es fundamental para el diagnóstico. En el examen físico inicial, la diferenciación de un vértigo de origen central de otro de origen periférico, puede realizarse mediante el análisis del nistagmo, la valoración del impulso cefálico y la desviación ocular, que se integran en un sistema denominado HINTS, por sus siglas en inglés (Head Impulse, Nystamus type, Test of Skew), y por la realización de pruebas que evalúen también la vía vestíbulo-cerebelosa. Además, la realización de una audiometría tonal, aumentaría la sensibilidad diagnóstica de 71 a 89% en la evaluación inicial. El diagnóstico apropiado es la base para el tratamiento y control de esta condición clínica en el mediano y largo plazo.

Vertigo is defined as an abnormal sensation of body motion or of its surrounding objects. It is a common chief complaint in emergency departments comprising 2 to 3% of these consultations worldwide. Vertigo is classified as peripheral or central, according to its origin, and can also be occasionally mixed, the most common cause of peripheral involvement being benign paroxysmal positional vertigo. The initial findings on clinical evaluation of patients are the clues for making a correct diagnosis. The differentiation between central and peripheral vertigo can be optimized by analysing nystagmus, by using the skew test and the head impulse test (HINTS), as also by performing the appropriate tests to evaluate the integrity of the vestibular-cerebellar pathway. In addition, tonal threshold audiometry could raise the diagnostic sensibility from 71 to 89% on initial approach. Appropriate diagnosis is the principal key for managing this clinical condition.

25 (OH) D3 levels, incidence and recurrence of different clinical forms of benig paroxysmal positional vertigo / Níveis de 25 (OH) D3, incidência e recorrência de diferentes formas clínicas de vertigem posicional paroxística benigna

Abstract Introduction Benign paroxysmal positional vertigo is the most common cause of dizziness in the general population. It is a condition with potential impact of reduced levels of vitamin D on its recurrent attacks. Objectives The aim of this study was to measure the serum levels of 25-hydroxyvitamin D3 (25-OH D3) in patients with benign paroxysmal positional vertigo and determine whether there is a difference in the serum levels of vitamin D3 between patients with and without recurrence, as well as between the different clinical forms of benign paroxysmal positional vertigo. Methods The study included 40 patients who came to the regular medical examination, diagnosed with posterior canal-benign paroxysmal positional vertigo based on the positive Dix-Hallpike's test. All patients underwent Epley manoeuvre after the diagnosis. Patients were classified according to current guidelines for levels of vitamin D3 in the serum in three groups: the deficiency, insufficiency and adequate level. Results The average serum level of 25-OH D3 among respondents was 20.78 ng/mL, indicating a lack or insufficiency of the aforementioned 25-OH D3. According to the levels of 25-OH D3, most patients suffer from deficiency (47.5%). 7 (17.5%) respondents had adequate blood level of 25-OH D3, and 14 (35%) respondents suffer from insufficiency. A significant difference was not found in the serum level of 25-OH D3 between patients with and without benign paroxysmal positional vertigo recurrence. There was a significant difference in the serum levels of 25-OH D3 in comparison to the clinical form of the disease. Lower 25-OH D3 values were found in patients with canalithiasis compared to those with cupulolithiasis. Conclusions There were no significant differences in the vitamin D3 serum level in patients with and without recurrence. The study showed a low level of serum vitamin D3 in most patients, indicating the need for supplemental therapy.

Resumo Introdução Vertigem posicional paroxística benigna é a causa mais comum de tonturas na população em geral. É uma condição no qual níveis reduzidos de vitamina D podem ter um potencial impacto para o desenvolvimento de crises recorrentes. Objetivos O objetivo desse estudo foi medir os níveis séricos de 25-hidroxivitamina D3 (25-OH D3) em pacientes com vertigem posicional paroxística benigna e determinar se há diferença nos níveis séricos de vitamina D3 entre pacientes com e sem recorrência, bem como entre as diferentes formas clínicas de vertigem posicional paroxística benigna. Método O estudo incluiu 40 pacientes submetidos a exame médico regular, diagnosticados com vertigem posicional paroxística benigna de canal posterior baseado no resultado positivo do teste de Dix-Hallpike. Todos os pacientes foram submetidos à manobra de Epley após o diagnóstico. Os pacientes foram classificados de acordo com as diretrizes atuais para os níveis de vitamina D3 sérica em três grupos: deficiência, insuficiência e nível adequado. Resultados O nível sérico médio de 25-OH D3 entre os indivíduos avaliados foi de 20,78 ng/mL, indicando falta ou insuficiência desta vitamina. De acordo com os níveis de 25-OH D3, a maioria dos pacientes apresentou deficiência (47,5%). Sete indivíduos (17,5%) entrevistados tinham nível sanguíneo adequado de 25-OH D3 e 14 (35%) apresentavam insuficiência. Não foi encontrada diferença significativa no nível sérico de 25-OH D3 entre pacientes com e sem recidiva de vertigem posicional paroxística benigna. Houve uma diferença significativa nos níveis séricos de 25-OH D3 de acordo com a forma clínica da doença. Baixos níveis de 25-OH D3 foram mais encontrados em pacientes com canalitíase em comparação com aqueles com cupulolitíase. Conclusões Não houve diferenças significativas no nível sérico de vitamina D3 em pacientes com e sem recorrência. O estudo mostrou um baixo nível de vitamina D3 sérica na maioria dos pacientes, indicando a necessidade de terapia suplementar.

Tumarkin-like phenomenon as a sign of therapeutic success in benign paroxysmal positional vertigo / Fenômeno Tumarkin-like como sinal de sucesso terapêutico na vertigem posicional paroxística benigna

ABSTRACT Objective: To describe an unusual patient reaction to maneuvers used in the treatment of posterior canal benign paroxysmal positional vertigo (PC-BPPV) that we termed the "Tumarkin-like phenomenon". Methods: At a private practice, 221 outpatients were diagnosed and treated for PC-BPPV. The treatment consisted of performing the Epley or Semont maneuvers. At the end of these maneuvers, when assuming the sitting position, the patients' reactions were recorded. Results: Thirty-three patients showed a Tumarkin-like phenomenon described by a self-reported sensation of suddenly being thrown to the ground. In the follow-up, this group of patients remained without PC-BPPV symptoms up to at least 72 hours after the maneuvers. Conclusion: The occurrence of a Tumarkin-like phenomenon at the end of Epley and Semont maneuvers for PC-BPPV may be linked with treatment success.

RESUMO Objetivo: Descrever uma reação incomum dos pacientes às manobras utilizadas no tratamento da vertigem posicional paroxística benigna do canal posterior (VPPB-CP), a qual denominamos de fenômeno Tumarkin-like. Métodos: Em uma clínica privada, 221 pacientes ambulatoriais foram diagnosticados e tratados para VPPB-CP. O tratamento consistiu em realizar as manobras de Epley ou de Semont. Ao término da manobra, ao serem colocados na posição sentado, as reações dos pacientes foram filmadas. Resultados: Trinta e três pacientes apresentaram o fenômeno de Tumarkin-like, descrito como uma sensação súbita de ser jogado no chão. O acompanhamento mostrou que todos eles permaneceram sem sintomas de VPPB até pelo menos 72 horas após as manobras. Conclusão: A ocorrência do fenômeno Tumarkin-like no final das manobras de Epley e Semont para VPPB-CP pode estar associado ao sucesso terapêutico.

Subjective visual vertical after treatment of benign paroxysmal positional vertigo / Vertical visual subjetiva após tratamento da vertigem posicional paroxística benigna

Abstract Introduction: Otolith function can be studied by testing the subjective visual vertical, because the tilt of the vertical line beyond the normal range is a sign of vestibular dysfunction. Benign paroxysmal positional vertigo is a disorder of one or more labyrinthine semicircular canals caused by fractions of otoliths derived from the utricular macula. Objective: To compare the subjective visual vertical with the bucket test before and immediately after the particle repositioning maneuver in patients with benign paroxysmal positional vertigo. Methods: We evaluated 20 patients. The estimated position where a fluorescent line within a bucket reached the vertical position was measured before and immediately after the particle repositioning maneuver. Data were tabulated and statistically analyzed. Results: Before repositioning maneuver, 9 patients (45.0%) had absolute values of the subjective visual vertical above the reference standard and 2 (10.0%) after the maneuver; the mean of the absolute values of the vertical deviation was significantly lower after the intervention (p < 0.001). Conclusion: There is a reduction of the deviations of the subjective visual vertical, evaluated by the bucket test, immediately after the particle repositioning maneuver in patients with benign paroxysmal positional vertigo.

Resumo Introdução: A função do otólito pode ser estudada por meio de testes da vertical visual subjetiva, porque a inclinação da linha vertical além da faixa normal é um sinal de disfunção vestibular. A vertigem postural paroxística benigna é um distúrbio de um ou mais canais semicirculares labirínticos causado por frações de otólitos derivados da mácula utricular. Objetivo: Comparar a vertical visual subjetiva com o teste do balde antes e imediatamente após a manobra de reposicionamento de partículas em pacientes com vertigem posicional paroxística benigna. Método: Foram avaliados 20 pacientes. A posição estimada, onde uma linha de fluorescência dentro de um balde atingia a posição vertical, foi medida antes e imediatamente após a manobra de reposicionamento de partículas. Os dados foram tabulados e analisados estatisticamente. Resultados: Antes da manobra de reposicionamento, nove pacientes (45%) apresentaram valores absolutos de vertical visual subjetiva acima da referência padrão e dois (10%) depois da manobra; a média dos valores absolutos do desvio vertical foi significativamente mais baixa depois da intervenção (p < 0,001). Conclusão: Há uma redução dos desvios da vertical visual subjetiva, avaliada pelo teste do balde, imediatamente após a manobra de reposicionamento de partículas em pacientes com vertigem posicional paroxística benigna.

Diagnostic value of repeated Dix-Hallpike and roll maneuvers in benign paroxysmal positional vertigo / Valor diagnóstico da repetição das manobras de Dix-Hallpike e roll-test na vertigemposicional paroxística benigna

Abstract Introduction: Benign Paroxysmal Positional Vertigo (BPPV) is the most common peripheral vestibular disorder. The Dix-Hallpike and Roll maneuvers are used to diagnose BPPV. Objective: This study aims to investigate the diagnostic value of repeated Dix-Hallpike and Roll maneuvers in BPPV. Methods: We performed Dix-Hallpike and roll maneuvers in patients who admitted with peripheral vertigo anamnesis and met our criteria. The present study consists of 207 patients ranging in age from 16 to 70 (52.67 ± 10.67). We conducted the same maneuvers sequentially one more time in patients with negative results. We detected patients who had negative results in first maneuver and later developed symptom and nystagmus. We evaluated post-treatment success and patient satisfaction by performing Dizziness Handicap Inventory (DHI) at first admittance and two weeks after treatment in all patients with BPPV. Results: Of a total of 207 patients, we diagnosed 139 in first maneuver. We diagnosed 28 more patients in sequentially performed maneuvers. The remaining 40 patients were referred to imaging. There was a significant difference between pre- and post-treatment DHI scores in patients with BPPV (p < 0.001). Conclusion: Performing the diagnostic maneuvers only one more time in vertigo patients in the first clinical evaluation increases the diagnosis success in BPPV. Canalith repositioning maneuvers are effective and satisfactory treatment methods in BPPV.

Resumo Introdução: Vertigem posicional paroxística benigna (VPPB) é a disfunção vestibular periférica mais comum. As manobras de Dix-Hallpike e roll-test são usadas para diagnosticar a VPPB. Objetivo: Este estudo teve como objetivo investigar o valor diagnóstico da repetição das manobras de Dix-Hallpike e roll-test na VPPB. Método: Manobras de Dix-Hallpike e Roll-test foram realizadas nos pacientes que foram internados com história de vertigem periférica e eram adequados aos nossos critérios. O presente estudo contou com 207 pacientes na faixa etária de 16-70 anos (52,67 ± 10,67). Fizemos uma vez mais as mesmas manobras sequencialmente nos pacientes com resultados negativos. Detectamos os pacientes que tiveram resultados negativos na primeira manobra e que posteriormente desenvolveram sintomas e nistagmo. Avaliamos o sucesso pós-tratamento e a satisfação do paciente mediante o Inventário da Deficiência Física na Vertigem (Dizziness Handicap Inventory - DHI) na primeira admissão e duas semanas após o tratamento em todos os pacientes com VPPB. Resultados: De 207 pacientes, 139 foram diagnosticados na primeira manobra. Diagnosticamos mais 28 pacientes nas manobras feitas consecutivamente. Os 40 pacientes restantes foram encaminhados para exames de imagem. Houve diferença significativa entre os escores do DHI pré- e pós-tratamento nos pacientes com VPPB (p < 0,001). Conclusão: A realização das manobras diagnósticas apenas mais uma vez nos pacientes com vertigem na primeira avaliação clínica aumentou o sucesso do diagnóstico em VPPB. As manobras de reposicionamento canalicular são métodos eficazes e satisfatórios de tratamento na VPPB.

Características epidemiológicas y comorbilidades asociadas en pacientes con migraña vestibular definida en Hospital Británico de Buenos Aires: 2014-2016 / Epideniologic characteristics and associated comorbidities in patients with vestibular migraine, Buenos Aires British Hospital: 2014-2016 / Aspectos epidemiológicos e comorbidades em pacientes com enaxaqueca vestibular no Hospital Británico de Buenos Aires:2014 - 2016

Introducción: la migraña vestibular definida es una de las causas más comunes de vértigo, así como el vértigo paroxístico benigno e hidrops endolinfático. Su prevalencia en la población general se ha estimado entre 1,1 a 3,2%. En Latinoamérica son pocos los estudios acerca de las características epidemiológicas y las comorbilidades adjuntas de los pacientes con diagnóstico de migraña vestibular. Este trabajo describe la correlación entre las características epidemiológicas y las comorbilidades adjuntas de los pacientes evaluados por migraña vestibular definida en el Hospital Británico de Buenos Aires en el periodo comprendido entre enero de 2014 y febrero de 2016. Materiales y métodos: Se realizó un estudio observacional descriptivo retrospectivo con revisión manual de historias clínicas de pacientes evaluados en la consulta de otorrinolaringología. Resultados: El estudio mostró que la edad media de los pacientes con migraña vestibular definida fue 44,4 años, observándose mayor número de consultas por pacientes del sexo femenino. Las comorbilidades no otoneurológicas más frecuentes encontradas en el sexo masculino fueron epilepsia y diabetes mellitus tipo II y en el sexo femenino depresión. La comorbilidad otoneurológica más frecuentemente encontrada tanto en el sexo masculino como femenino fue hidrops endolinfático. Conclusiones: En la población las consultas fueron en mayor número de mujeres con una edad media de 44,4 años. Las comorbilidades no otoneurológicas encontradas en hombres fueron epilepsia y diabetes mellitus tipo II y en mujeres depresión. La comorbilidad otoneurológica más encontrada tanto en hombres como en mujeres fue hidrops endolinfático.

Introduction: defined Migraine associated- vertigoisone of the most common etiologies of vertigo as peripheric benign vertigo and endolympatic hydrops are. Its prevalence on population is estimated between 1.1 to 3.2%. In Latin America there are few studies about epidemiologic characteristics and comorbidities of diagnosed patients with defined migraine associated vertigo. This work describes the relationship between the epidemiologic characteristics and the comorbidities of patients evaluated for defined migraine associated vertigo at Buenos Aires British Hospital since january 2014 to february 2016. Methods: An observational, descriptive and retrospective study was done. Clinical records of otolaryngology consult were reviewed. Results: This study showed a mean age of 44.4 years old for the patients of defined migraine associated vertigo, the majority of consults were done for female gender. The most common non – neurotological comorbidities found in male gender were epilepsy and diabetes mellitus type II and in female gender was depression. The most common neurotological condition found in female and male gender was endolympatic hydrops. Conclusions: The majority of consults were achieved by female population with a mean age of 44.4 years old. Non-neurotological comorbidities found in men were epilepsy and diabetes mellitus type II and in women depression. The most common neurotological comorbidity found in men and women was endolymphatic hydrops.

Introdução: a enxaqueca vestibular definitiva é uma das causas mais comuns de vertigem e vertigem paroxística benigna e hidropisia endolinfática. A sua prevalência na população em geral tem sido estimado entre 1,1 e 3,2%. Na América Latina existem poucos estudos sobre a epidemiologia e as co-morbidades que acompanham de pacientes com diagnóstico de enxaqueca vestibular. Este artigo descreve a correlação entre as características epidemiológicas e as co-morbidades que acompanham de pacientes avaliados para a enxaqueca vestibular definidos no Hospital Britânico de Buenos Aires no período compreendido entre Janeiro de 2014 e Fevereiro de 2016. Materiais e métodos: um estudo observacional retrospectivo com revisão manual dos prontuários de pacientes avaliados em consulta de otorrinolaringologia foi realizado. Resultados: O estudo mostrou que a idade média dos pacientes com enxaqueca vestibular definitiva foi de 44,4 anos, mostrando mais consultas por parte de pacientes do sexo feminino. As comorbidades mais freqüentes não otoneurológicas encontrados nos machos foram epilepsia e diabetes mellitus tipo II e depressão em mulheres. A comorbidade otoneurológico mais frequentemente encontrado em ambos os sexos masculino e feminino foi hidropisia endolinfática. Conclusões: na população nas consultas eram mais mulheres com uma idade média de 44,4 anos. Os homens não otoneurológicas comorbidades foram encontrados em epilepsia e diabetes mellitus tipo ii depressão e mulheres. Quanto mais comorbidade otoneurológico encontrados em homens e mulheres era de hidropisia endolinfática.