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1.
An. bras. dermatol ; 95(3): 278-282, May-June 2020. tab, graf
Artigo em Inglês | LILACS, Coleciona SUS | ID: biblio-1130884

RESUMO

Abstract Background: The hair follicle is a unique structure, one of the most dynamic structures in mammalians, which can reproduce in every new cycle all the mechanism involved in its fetal development. Although a lot of research has been made about the human hair follicle much less has been discovered about the importance of the cytokeratins (CKs) in its development. Objective: Study the immunohistochemical pattern of epithelial CKs during human hair follicle development. Methods: We performed an immunohistochemical study using fresh post-mortem skin biopsies of human fetuses between 4 and 25 weeks of gestational age to study the expression of cytokeratins (CKs): CK1, CK10, CK13, CK14, CK16 and CK20 during human hair follicle fetal development. Study limitations: Restrospective study with a good number of makers but with a small population. Results/conclusion: We found that, the CKs were expressed in an intermediate time during follicular development. The epithelial CKs (CK1, CK14, CK10, CK13) and the epithelial CKs with a proliferative character such as CK16 were expressed first, as markers of cellular maturation and follicular keratinization. At a later phase, CK20 was expressed in more developed primitive hair follicles as previously discussed in literature.


Assuntos
Folículo Piloso/cirurgia , Folículo Piloso/crescimento & desenvolvimento , Queratinas Específicas do Cabelo/análise , Imuno-Histoquímica , Estudos Retrospectivos , Fatores Etários , Idade Gestacional , Desenvolvimento Fetal , Anticorpos Monoclonais/análise
2.
Braz. J. Pharm. Sci. (Online) ; 54(3): e17339, 2018. tab, graf
Artigo em Inglês | LILACS | ID: biblio-974410

RESUMO

Technological progress has allowed women to change their natural hair configuration according to their will. This type of treatment is very popular around the world, even involving the use of prohibited chemicals, such as formaldehyde. Studies of hair characterization, straighteners and toxic evaluation are available in the literature, although few studies have evaluated the consumer profile or the current legislation of Brazil and the European Union (EU) and its influence on the consumption of hair straighteners. Previous studies from our research group have shown that hair care is essential for the quality of life and well-being of women. Within this context, the present study aimed to evaluate the profile of Brazilian hair straightener consumers, as well as the legislation of Brazil and the EU and its influence on the use of these products. The consumer profile was evaluated by applying questionnaires and the legislation was examined using documental and bibliographic exploratory research. The results provided a full understanding of the current legislation of Brazil and its similarities to EU legislation. It was observed that over 50% of Brazilians currently use or have previously used hair straightener products, even persons who do not have curly hair, suggesting that straight hair is more attractive for today's society. Although the study participants consider the current legislation to be important, over 40% do not know the active ingredients present in the hair straightener they use. Finally, the legislation is not considered in terms of the daily hair treatment routine, with the esthetic result being more important to the consumer


Assuntos
Comportamento do Consumidor , Queratinas Específicas do Cabelo/efeitos adversos , Preparações para Cabelo , Inquéritos e Questionários/estatística & dados numéricos , Agência Nacional de Vigilância Sanitária , Formaldeído/farmacologia , Legislação como Assunto/estatística & dados numéricos
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