The effects of positive end-expiratory pressure (PEEP) application on optic nerve sheath diameter in patients undergoing laparoscopic cholecystectomy: a randomized trial

Abstract Background: Positive end-expiratory pressure (PEEP) can overcome respiratory changes that occur during pneumoperitoneum application in laparoscopic procedures, but it can also increase intracranial pressure. We investigated PEEP vs. no PEEP application on ultrasound measurement of optic nerve sheath diameter (indirect measure of increased intracranial pressure) in laparoscopic cholecystectomy. Methods: Eighty ASA I-II patients aged between 18 and 60 years scheduled for elective laparoscopic cholecystectomy were included. The study was registered in the Australian New Zealand Clinical Trials (ACTRN12618000771257). Patients were randomly divided into either Group C (control, PEEP not applied), or Group P (PEEP applied at 10 cmH20). Optic nerve sheath diameter, hemodynamic, and respiratory parameters were recorded at six different time points. Ocular ultrasonography was used to measure optic nerve sheath diameter. Results: Peak pressure (PPeak) values were significantly higher in Group P after application of PEEP (p = 0.012). Mean respiratory rate was higher in Group C at all time points after application of pneumoperitoneum (p < 0.05). The mean values of optic nerve sheath diameters measured at all time points were similar between the groups (p > 0.05). The pulmonary dynamic compliance value was significantly higher in group P as long as PEEP was applied (p = 0.001). Conclusions: During laparoscopic cholecystectomy, application of 10 cmH2O PEEP did not induce a significant change in optic nerve sheath diameter (indirect indicator of intracranial pressure) compared to no PEEP application. It would appear that PEEP can be used safely to correct

Contribuições da mobilidade acadêmica internacional realizada na austrália para a formação da enfermeira no brasil / Aportes de movilidad académica internacional realizados en australia para la formación de enfermeras en brasil / Contributions of international academic mobility held in australia for the training of nurses in brazil

Objetivo: identificar as contribuições da mobilidade acadêmica internacional, realizada na Austrália, para a formação da enfermeira no Brasil. Método: estudo exploratório com abordagem qualitativa, realizado com oito ex-intercambistas do Programa Ciência sem Fronteiras. A análise foi feita pela proposta do Discurso do Sujeito Coletivo. Resultados: a experiência ofereceu às (ex)intercambistas uma gama de oportunidades e de trocas de experiências para a formação em enfermagem. Foi apontada a rica experiência em cursar disciplinas na Austrália, comparando a metodologia Problem Based Learning com a metodologia tradicional vivenciada no Brasil e destacando seus efeitos positivos. O intercâmbio proporcionou desenvolvimento de habilidades técnico-científicas e interpessoais, vivências de sistemas comparados de saúde, além de aperfeiçoamento das competências linguísticas e de construção de compromisso ético-político-social e perspectivas profissionais futuras. Considerações finais: a mobilidade acadêmica internacional contribuiu positivamente na formação das enfermeiras brasileiras, com evidência de desenvolvimento pessoal e profissional.

Objetivo: identificar las contribuciones de la movilidad académica internacional, realizada en Australia, a la formación de enfermeras en Brasil. Método: estudio exploratorio con enfoque cualitativo, realizado con ocho ex alumnos de intercambio del programa Ciencia sin Fronteras. El análisis se realizó mediante la propuesta del Discurso del Sujeto Colectivo. Resultados: la experiencia ofreció a los estudiantes (ex)de intercambio una gama de oportunidades e intercambio de experiencias para la educación de enfermería. Se señaló la rica experiencia en el estudio de asignaturas en Australia, comparando la metodología de Aprendizaje Basado en Problemas con la metodología tradicional experimentada en Brasil y destacando sus efectos positivos. El intercambio proporcionó el desarrollo de habilidades técnico-científicas e interpersonales, experiencias de comparación de sistemas de salud, además de mejorar las habilidades lingüísticas y construir un compromiso ético-político-social y perspectivas profesionales de futuro. Consideraciones finales: la movilidad académica internacional contribuyó positivamente a la formación de enfermeras brasileñas, con evidencia de desarrollo personal y profesional.

Objective: to identify the contributions of international academic mobility, carried out in Australia, to the training of nurses in Brazil. Method: exploratory study with qualitative approach, conducted with eight former exchange students of the Science Without Borders program. The analysis was made by the proposal of the Collective Subject Discourse. Results: the experience offered (ex)exchange students a range of opportunities and exchange of experiences for nursing education. The rich experience in studying subjects in Australia was pointed out, comparing the Problem Based Learning methodology with the traditional methodology experienced in Brazil and highlighting its positive effects. The exchange provided the development of technical-scientific and interpersonal skills, experiences of comparing health systems, in addition to improving language skills and building an ethical-political-social commitment and future professional perspectives. Final considerations: international academic mobility contributed positively to the training of Brazilian nurses, with evidence of personal and professional development.

O coelho é a saúva: a proposta brasileira e o uso do vírus do mixoma (MYXV) contra a praga de coelhos na Austrália, 1896-1952 / Rabbits and leaf-cutting ants: the Brazilian plan to use the myxoma virus (MYXV) against rabbit plagues in Australia, 1896-1952

Resumo O artigo analisa a singularidade dos processos históricos, científicos e políticos que vão da descoberta da doença que passou a ser conhecida como mixomatose infecciosa, causada pelo vírus do mixoma (MYXV), à sua aplicação no controle de uma praga de coelhos na Austrália. A narrativa segue especialmente as pesquisas de Henrique de Beaurepaire Aragão, pesquisador do Instituto Oswaldo Cruz, e posteriormente os esforços da cientista Jean Macnamara para promover pesquisas e implementar o MYXV na Austrália. Foram consultadas notas de pesquisa de cientistas, documentos oficiais que registraram o desenvolvimento dos experimentos, bem como periódicos. Nesse processo, foi considerado o desenvolvimento histórico do campo de estudos da virologia e controle biológico.

Abstract This article analyzes the singularity of historical, scientific, and political processes from the discovery of the disease caused by the myxoma virus (MYXV) that came to be known as infectious myxomatosis to the application of this virus against a plague of rabbits in Australia. This narrative focuses on research by Henrique de Beaurepaire Aragão, a researcher at the Oswaldo Cruz Institute, and later efforts by the scientist Jean Macnamara to promote studies and implement MYXV in Australia. The scientists' research notes were consulted, along with official documents recording the experiments and periodicals. In this process, the historical development of virology and biological controls as a field of study was also considered.

Dental displacement in complete dentures influenced by different flask types and polymerization cycles

Abstract This study evaluated the dental displacement in dentures included in different flasks and processed by the Australian cycle modified or by microwave. Metal pins were placed on the teeth as reference for measurements: a) Incisal edge of maxillary and mandibular central incisors, buccal cusp of maxillary and mandibular vestibular first premolars, and mesiobuccal maxillary and mandibular cusps of second molars; b) Incisor to incisor, premolar to premolar and molar to molar; c) Left incisor to left molar and right incisor to right molar, and d) Vertical. Dentures were divided according to flasks (n=10): G1- Metal; G2- HH bimaxillary metal; G3-Microwaves; G4- HH bimaxillary microwaves. For G1 and G2, polymerization at 65ºC/30 min, flame quenched for 30 min, heating at 65ºC/30 min, boiling water for 1 h. For G3 and G4, microwave (20 min/140 W and 5 min/560 W). Comparator microscope with digital camera and analytical unit assessed the measurements before and after denture polymerization. The final distance was made subtracting the distance before the denture processing from the distance of the dental displacement after processing. The value of the difference was submitted to 2-way ANOVA, considering the flask type and denture type. Maxillary denture showed greater displacement when compared to mandibular denture. Flask types and interaction with denture types showed similar difference between before and after polymerization. In conclusion, displacement promoted by flask types in dentures cured by polymerization cycles promoted similar effect on the distance between teeth. Greater value for distance between teeth occurred for maxillary denture.

Resumo O objetivo neste estudo foi avaliar o deslocamento dental em próteses totais incluídas em diferentes tipos de muflas e polimerizadas pelo ciclo australiano ou por micro ondas. Pinos metálicos foram colocados nos dentes como pontos de referência para as medidas: a) Borda incisal dos incisivos centrais maxilares e mandibulares, cúspide vestibular dos primeiros pré molares maxilares e mandibulares e cúspides mésiovestibulares dos segundos molares maxilares e mandibulares; b) Distâncias látero-laterais incisivo a incisivo, pré-molar a pré-molar e molar a molar; c) Distâncias horizontais anteroposterior incisivo esquerdo a molar esquerdo e incisivo direito a molar direito, e d) Vertical. As próteses foram separadas de acordo com o tipo de mufla (n=20): G1- Metálica; G2-HH bi-maxilar metálica; G3- Micro-ondas; G4- HH bi-maxilar micro ondas. Ciclo de polimerização para G1 e G2, água a 65ºC por 30 minutos, aquecimento interrompido por 30 minutos, reaquecimento a 65ºC por 30 minutos, seguido de água fervente por 1 hora. Para G3 e G4, micro ondas (20 minutos a 140 W e 5 minutos a 560 W). As medidas foram avaliadas com microscópio comparador linear. A distância final entre os dentes foi obtida subtraindo o valor da distância antes do processamento da prótese do valor da distância resultante do deslocamento dentário após o processamento. A diferença obtida entre essas distâncias foi submetida à ANOVA de 2 fatores, considerando como variáveis tipo de mufla e tipo de prótese. A prótese maxilar apresentou maior deslocamento dental quando comparada à mandibular. Os tipos de muflas e a interação com os tipos de próteses mostraram movimentos dentais similares antes e depois da polimerização. Em conclusão, o deslocamento dental promovido por diferentes tipos de frascos em próteses curadas por diferentes ciclos de polimerização promoveu efeito semelhante na alteração da distância entre os dentes. Maior valor para a mudança de distância entre os dentes ocorreu na prótese maxilar.

Anatomy commemoration for body donors at Macquarie University, Sydney, Australia / Conmemoración de la anatomía para donantes de cuerpos en la Universidad Macquarie, Sydney, Australia

SUMMARY: Modern anatomy education is imbued with humanistic values which manifest primarily in the ethical acquisition of bodies for research and education, and respectful treatment of these bodies in anatomy laboratories. This humanistic approach is best embedded in the organisation of commemorative ceremonies for body donors. This paper presents experiences of preparation and implementation of a commemorative ceremony at Macquarie University, Sydney. Local cultural context and university infrastructure were considered when preparing the commemoration. It was decided that it will be introduced in stages, starting with a ceremony for anatomy students. Students were surveyed about the introduction of the ceremony and their attitudes about its format. The results of the survey influenced the format in which the commemoration was conducted. The commemoration was introduced in 2019, embedded in the first anatomy lecture. Such format was cost effective, caused little disturbance to a complex timetable and was aligned with learning outcomes and students' cultural preferences. It also enabled easy transition to the online modes of the delivery caused by the COVID-19 pandemic in Australia. In the next stage commemorative ceremony will be inclusive of donor family members as well as students.

RESUMEN: La educación en anatomía moderna está incentivada de valores humanistas que se manifiestan principalmente en la adquisición ética de cuerpos para la investigación y la educación, y en el trato respetuoso de estos cuerpos en los laboratorios de anatomía. Este enfoque humanista se integra mejor en la organización de ceremonias conmemorativas para donantes de cuerpos. Este documento presenta las experiencias de preparación e implementación de una ceremonia conmemorativa en la Universidad Macquarie, Sydney. Se tuvo en cuenta el contexto cultural local y la infraestructura universitaria al preparar la conmemoración. Se decidió que se presentará por etapas, comenzando con una ceremonia para estudiantes de anatomía. Los estudiantes fueron encuestados sobre la presentación de la ceremonia y sus actitudes sobre su formato. Los resultados de la encuesta influyeron en el formato en el que se llevó a cabo la conmemoración. La conmemoración se introdujo en 2019, como parte de la primera conferencia de anatomía. El formato era rentable, causaba pocas alteraciones en un horario complejo y estaba alineado con los resultados del aprendizaje y las preferencias culturales de los estudiantes. También permitió la transición a los modos en línea de la entrega causada por la pandemia de COVID-19 en Australia. En la siguiente etapa, la ceremonia conmemorativa incluirá a los miembros de la familia donante y a los estudiantes.

La pandemia de COVID-19, estudio de casos: Australia, Nueva Zelandia y Cuba / COVID-19 pandemic; case studies: Australia, New Zealand and Cuba

Introducción: La COVID-19, enfermedad respiratoria viral, producida por el SARS- CoV- 2, los primeros casos aparecieron en Wuhan, China, en diciembre 2019, evolucionó a pandemia. La OMS declaró emergencia mundial el 30 de enero del 2020. Se presentan los datos generales de la epidemia en Cuba, Australia y Nueva Zelandia. Objetivo: Describir la evolución de la epidemia en dichos países, las medidas tomadas y sus resultados. Material y Métodos: Investigación descriptiva, cuanti - cualitativa, utilizó la revisión documental, para cotejar información publicada sobre la epidemia en los países seleccionados, en revistas médicas, prensa periódica, sitios web oficiales. Se analizó información hasta el 13 de junio. Resultados: Australia tuvo 7 283 casos, 6 888 (94,48 por ciento) recuperados. Realizaron 1 782 651 test diagnósticos (69,91 por 10 000 habitantes) y positividad de 0.4 por ciento. Reportaron 102 fallecidos, mayores tasas entre 70 - 89 años, letalidad de 1,39 por ciento. Nueva Zelandia totalizó 1 515 casos, con 1 483 recuperados (97,8 por ciento), fallecieron 22. Realizaron 310 297 (36 por 10 000 habitantes) pruebas de PCR, con 0,7 por ciento de positivos. La letalidad fue de 1,9 por ciento. Cuba, acumulaba 2 238 casos, recuperados 1 923 (86 por ciento). Fallecieron 84 pacientes, con letalidad de 3,75 por ciento. Realizaron PCR (12,16 x 10 000 hab.), con 1,7 por ciento positivas. Conclusiones: El control resultó de la voluntad política de enfrentar y contener la epidemia con drásticas medidas de distanciamiento social, cierre de fronteras y aislamiento de territorios, aplicación de test diagnósticos, y la existencia de sistemas de salud públicos robustos y gratuitos(AU)

Introduction: COVID-19 is a viral respiratory disease produced by SARS-CoV-2. The first cases were diagnosed in Wuhan, China in December 2019; then the disease became a pandemic. The WHO declared it a global emergency on January 30, 2020. General data on the epidemic in Cuba, Australia and New Zealand are presented. Objective: To present the evolution of the epidemic in these countries as well as the measures taken and their results. Material and Methods: A descriptive, quantitative and qualitative research used documentary review to compare information about the epidemic in the selected countries. The information was obtained from medical journals, periodical press, and official websites and it was analyzed before June 13. Results: Australia had 7,283 cases of which 6,888 (94.48 percent) patients recovered. They performed 1,782,651 diagnostic tests (69.91 per 10,000 inhabitants) and the positivity was 0.4 percent. They reported 102 deaths with higher rates in people aged 70 - 89 years, and a case fatality of 1.39 percent. New Zealand reported 1,515 cases, with 1,483 recovered (97.8 percent) and 22 deaths. They performed 310,297 (36 per 10,000 population) PCR tests, with 0.7 percent positive cases. The case fatality was 1.9 percent. Cuba accumulated 2,238 cases and 1,923 (86 percent) recovered. A total of 84 patients died, with a lethality of 3.75 percent. PCR tests (12.16 x 10,000 inhabitants) were performed reporting 1.7 percent of positive cases. Conclusions: The control resulted from the political will to confront and contain the epidemic with drastic measures of social distancing, closure of borders and isolation of territories, application of diagnostic tests, and the existence of robust and free public health systems(AU)

A ciência da saúde coletiva por escrito: contribuição para estudos em saúde bucal coletiva / The science of collective health in writing: contribution to studies in collective oral health

Resumo Comemorando os 25 anos da Revista Ciência & Saúde Coletiva (C&SC), o presente artigo analisou 375 documentos publicados entre 2000-2019 neste periódico, como parte integrante da editoria de saúde bucal coletiva. A análise da produção visou compreender como o núcleo de saúde bucal aparece nas publicações e como poderia ter contribuído com o conhecimento sobre a saúde-doença da população, as políticas públicas específicas, o ensino e a gestão dos serviços de saúde bucal no SUS. O processo privilegiou a análise bibliométrica e a de documentos. Foi possível explicitar a distribuição institucional dos autores, sua expressiva rede de colaboradores e a dimensão das citações das publicações inclusive no plano internacional. Os estados brasileiros mais presentes nas publicações foram São Paulo e Minas Gerais, seguidos por autores de Pernambuco, Rio Grande do Sul e Santa Catarina. As citações foram mais frequentemente do Brasil (85,14%), seguido por Estados Unidos (2,31%), Portugal (1,34%) e Austrália (1,34%). Conclui-se que, mesmo com limitações, C&SC se mostrou, inequivocamente, um potente instrumento de divulgação da produção científica na perspectiva da saúde bucal coletiva, possibilitando a divulgação e o intercâmbio de informações, facilitando a integração entre os pesquisadores e possibilitando um caminho da sua consolidação.

Abstract Celebrating the 25 years of existence of the Journal Ciência & Saúde Coletiva (C&SC), this paper analyzed 375 documents published between 2000-2019 as an integral part of the editorial of collective oral health. The production analysis aimed to understand how oral health core appears in publications and how it could have contributed to knowledge on the population's health-disease, specific public policies, education, and management of oral health services in the SUS. The process employed bibliometric and documental analysis. We could show the authors' territorial distribution, their extensive collaboration network, and the dimension of citations in publications, including the international plan. The Brazilian states most present in the publications were São Paulo and Minas Gerais, followed by authors from Pernambuco, Rio Grande do Sul, and Santa Catarina. Citations were more frequent in Brazil (85.14%), followed by the United States (2.31%), Portugal (1.34%), and Australia (1.34%). We concluded that, despite the limitations, the C&SC showed unequivocally a powerful instrument for the dissemination of scientific production from the perspective of collective oral health, enabling the exchange of information and facilitating the integration between researchers and enabling a path to its consolidation.

Trends in case-fatality rates of COVID-19 in the World, between 2019 - 2020 / Tendência das taxas de letalidade de covid-19 no mundo, entre 2019-2020

INTRODUCTION: CoV infections can potentially cause from a simple cold to a severe respiratory syndrome, such as the Severe Acute Respiratory Syndrome and the Middle East Respiratory Syndrome (MERS-CoV). The COVID-19 created a new reality for global healthcare modelsOBJETIVE: To evaluate trends in case-fatality rates of COVID-19 in the WorldMETHODS: We conducted a population-based time-series study using public and official data of cases and deaths from COVID-19 in Argentina, Australia, Brazil, Chile, China, Colombia, France, Germany, India, Iran, Italy, Japan, Mexico, Morocco, New Zealand, Nigeria, Peru, Saudi Arabia, South Africa, South Korea, Spain, Switzerland, United Kingdom, United States and Russian, between December, 2019 and August, 2020. Data were based on reports from European Centre for Disease Prevention and Control. COVID-19 was defined by the International Classification of Diseases, 10th revision (U07.1). A Prais-Winsten regression model was performed and the Daily Percentage Change (DPC) calculated determine rates as increasing, decreasing or flatRESULTS: During the study period, trends in case-fatality rates in the world were flat (DPC = 0.3; CI 95% [-0.2: 0.7]; p = 0.225). In Africa, Morocco had decreasing trends (DPC = -1.1; CI 95% [-1.5: -0.7]; p < 0.001), whereas it were increasing in South Africa (p < 0.05) and flat in Nigeria (p > 0.05). In the Americas, Argentina showed a decreasing trend in case-fatality rates (DPC = -0.6; CI 95% [-1.1: -0.2]; p = 0.005), the U.S. had flat trends (p > 0.05) and all other American countries had increasing trends (p < 0.05). In Asia, Iran had decreasing trends (DPC = -1.5; CI 95% [-2.6 : -0.2]; p = 0.019); China and Saudi Arabia showed increasing trends (p < 0.05), while in India, Japan and South Korea they were flat (p > 0.05). European countries had mostly increasing trends (p < 0.05): Germany, Italy, Spain, the UK and Russia; France and Switzerland had flat trends (p > 0.05). Finally, in Oceania, trends in case-fatality rates were flat in Australia (p > 0.05) and increasing in New Zealand (p < 0.05CONCLUSION: Trends in case-fatality rates of COVID-19 in the World were flat between December, 31 and August, 31. Argentina, Iran and Morocco were the only countries with decreasing trends. On the other hand, South Africa, Brazil, Canada, Chile, Colombia, Mexico, Peru, China, Saudi Arabia, Germany, Spain, United Kingdom, Russian and New Zealand had increasing trends in case-fatality rate. All the other countries analyzed had flat trends. Based on case-fatality rate data, our study supports that COVID-19 pandemic is still in progress worldwide

INTRODUÇÃO: As infecções por CoV podem causar desde um simples resfriado até uma síndrome respiratória grave, como a Síndrome Respiratória Aguda Grave e a Síndrome Respiratória do Oriente Médio (MERS-CoV). O COVID-19 impôs uma nova realidade em termos de modelos globais de saúdeOBJETIVO: Avaliar as tendências das taxas de letalidade do COVID-19 no mundoMÉTODO: Estudo de séries temporais de base populacional usando dados públicos e oficiais de casos e mortes por COVID-19 na Argentina, Austrália, Brasil, Chile, China, Colômbia, França, Alemanha, Índia, Irã, Itália, Japão, México, Marrocos, Nova Zelândia, Nigéria, Peru, Arábia Saudita, África do Sul, Coreia do Sul, Espanha, Suíça, Reino Unido, Estados Unidos (EUA) e Rússia, entre 31 dezembro de 2019 e 31 agosto de 2020. Os dados foram baseados nos relatórios do Centro Europeu de Prevenção e Controle de Doenças. COVID-19 foi definido pela Classificação Internacional de Doenças, 10ª revisão (U07.1). Para análise estatística, foi realizado o modelo de regressão de Prais-Winsten, a partir do qual foi possível calcular a variação percentual de mudança diária (DPC) das taxas, classificadas como crescentes, decrescentes ou estacionáriasRESULTADOS: Durante o período do estudo, as taxas de letalidade no mundo permaneceram estacionárias (DPC = 0,3; IC 95% [-0,2: 0,7]; p = 0,225). Na África, Marrocos teve tendência decrescente (DPC = -1,1; IC 95% [-1,5: -0,7]; p <0,001), enquanto na África do Sul houve tendência crescente (p < 0,05) e estacionária na Nigéria (p > 0,05). Em relação às Américas, a Argentina revelou tendência decrescente nas taxas de letalidade (DPC = -0,6; IC 95% [-1,1: -0,2]; p = 0,005), os EUA demonstraram tendência estacionária (p > 0,05) e todos os outros países americanos demonstraram tendências crescentes (p < 0,05). Na Ásia, o Irã apresentou tendência decrescente (DPC = -1,5; IC 95% [-2,6: -0,2]; p = 0,019); China e Arábia Saudita apresentaram tendências crescentes (p <0,05), enquanto Índia, Japão e Coreia do Sul mantiveram tendência estacionária (p > 0,05). A maioria dos países europeus apresentaram tendências crescentes (p <0,05): Alemanha, Itália, Espanha, Reino Unido e Rússia; França e Suíça demonstraram tendências estacionárias (p > 0,05). Por fim, na Oceania, a tendência nas taxas de letalidade na Austrália foi estacionária (p > 0,05) e aumentou na Nova Zelândia (p < 0,05CONCLUSÃO: A tendência nas taxas de letalidade por COVID-19 no mundo permaneceu estacionária entre 31 de dezembro de 2019 e 31 de agosto de 2020. Argentina, Irã e Marrocos foram os únicos países com tendências decrescentes. Por outro lado, África do Sul, Brasil, Canadá, Chile, Colômbia, México, Peru, China, Arábia Saudita, Alemanha, Espanha, Reino Unido, Rússia e Nova Zelândia apresentaram tendências crescentes de letalidade. Todos os outros países analisados demonstraram tendências estacionárias. De acordo com dados de letalidade, nosso estudo confirma que a pandemia de COVID-19 ainda está em fase de progressão em todo o mundo

Assessment of interspecific interactions between the invasive red-claw crayfish (Cherax quadricarinatus) and the Mozambique tilapia (Oreochromis mossambicus) / Avaliação das interações interespecíficas entre o lagostim invasivo de garra vermelha (Cherax quadricarinatus) e a tilapia de Moçambique (Oreochromis mossambicus)

Abstract The Australian red-claw crayfish, Cherax quadricarinatus, has been introduced for aquaculture purposes worldwide and consequently colonized natural environments, where it might cause ecosystem services losses or adversely affect native species and the local environment. This species was first found in Pequenos Libombos Reservoir in Maputo Province, Southern Mozambique in the late 2009 and is linked to reduction in tilapia fisheries. This study, conducted in 2015 under controlled conditions, aimed to assess the interspecific relationships between the Mozambique tilapia (Oreochromis mossambicus) and the alien crayfish. For both species, no significant differences in growth and survival rates were found between animals reared in the presence versus the absence of heterospecifics, indicating no direct deleterious interspecific effects. Behavioural observations revealed that fish and crayfish competed for shelter and food. Both species reduced the foraging in the presence of heterospecifics during feeding period, in the daytime. Crayfish seemed to have an advantage in competition for shelter, suggesting that they may interfere with tilapia sheltering activity and make tilapia vulnerable to predators in natural habitats.

Resumo O lagostim australiano, Cherax quadricarinatus, tem sido introduzido para fins de aquicultura em todo o mundo e, consequentemente, colonizado ambientes naturais, onde pode coexistir com a biota local sem causar perdas nos serviços dos ecossistemas ou afetar negativamente as espécies nativas e o meio ambiente local. Esta espécie foi encontrada pela primeira vez na Albufeira dos Pequenos Libombos, na Província de Maputo, sul de Moçambique, no final de 2009 e foi relacionada à redução da pesca de tilápias registrada na mesma localidade. Este estudo, conduzido em 2015 sob condições controladas, teve como objetivo avaliar as relações interespecíficas entre a tilápia de Moçambique (Oreochromis mossambicus) e o lagostim invasor (C. quadricarinatus). Para ambas espécies, não foram encontradas diferenças significativas nas taxas de crescimento e sobrevivência entre animais criados na presença versus ausência de heteroespecíficos, indicando ausência de efeitos deletérios interespecíficos diretos. Observações comportamentais revelaram que peixes e lagostins competiam por abrigo e comida. Ambas espécies reduziram o forrageamento na presença de heteroespecíficos durante o período de alimentação, no período diurno. O lagostim parece ter uma vantagem na competição por abrigos, sugerindo que, em habitats naturais eles podem provocar o deslocamento de tilápias de seus abrigos, e deste modo tornar as tilápias vulneráveis aos predadores.

Pares articulares en prótesis primaria de cadera. ¿Existe alguna diferencia? / Bearing surfaces in primary hip arthroplasty. Is there any difference?

Resumen: Introducción: En un reemplazo total de cadera primario (RTC), diferentes materiales son los que se usan para las superficies de apoyo. En nuestro medio, las cabezas de metal o cerámica con polietileno altamente entrecruzado (PA) son los más utilizados. Estas combinaciones tienen buenos resultados, pero no es claro cuál es superior clínicamente. Basados en una revisión sistemática de la literatura y de los registros nacionales de artroplastía, el objetivo de este estudio es determinar si existe alguna diferencia significativa desde el punto de vista clínico. Material y métodos: Realizamos una revisión sistemática de la literatura y de los registros nacionales de artroplastía. Buscamos estudios en los que se compararan los tipos de superficie de contacto: cerámica-polietileno altamente entrecruzado (CP) y metal-polietileno altamente entrecruzado (MP), además de los registros nacionales de artroplastía que describieran, con un seguimiento mínimo de 10 años, la tasa de revisión según el tipo de superficie. El desenlace evaluado fue: tasa de revisión por cualquier causa según el tipo de superficie. Resultados: Dos de quince registros nacionales fueron incluidos: el registro australiano muestra una diferencia en la tasa de revisión a 15 años, comparando CP: 6.3 (IC 5.8, 6.7) contra MP: 5.1 (IC 4.6, 5.7). El registro de Nueva Zelanda no muestra diferencias en la tasa de revisión/100 componentes/año: CP de 0.54 (0.48-0.61) en comparación con MP de 0.61 (0.57-0.66). No encontramos estudios clínicos con los criterios de inclusión que respondan la pregunta de investigación. Conclusión: Los resultados de esta revisión muestran una alta supervivencia cuando se usa polietileno altamente entrecruzado; asimismo, los resultados son similares cuando se utilizan cabezas de cerámica o metálicas.

Abstract: Introduction: In primary hip replacement, different materials are used for bearing surfaces. In our medium metal or ceramic heads with highly crossed-linked polyethylene (PA) are the most used. These combinations have good results, but it is not clear which is clinically superior. The objective of this study is to determine whether there is any clinically significant difference based on a systematic review of the literature and national registries of arthroplasty. Material and methods: We conduct a systematic review of the literature and national registries of arthroplasty and we were looking for studies comparing bearing surfaces: ceramic-highly cross-linked polyethylene (CP) and metal-highly cross-linked polyethylene (MP); describing the revision rate according to the surface type with a minimum 10-year follow-up. The outcome evaluated was: review rate for any cause depending on surface type. Results: Two out of fifteen national registries were included. The Australian registry shows a difference in the 15-year revision rate: CP: 6.3 (IC 5.8, 6.7) vs MP: 5.1 (IC 4.6, 5.7). The New Zealand registry shows no differences in revision rate/100 components/year: CP 0.54 (0.48-0.61) vs MP 0.61 (0.57-0.66). We do not find clinical studies with inclusion criteria that answer the research question. Conclusion: The results of this review show a high survival rate with the use of highly cross-linked polyethylene, the results are similar when using ceramic or metal heads.

Aquí (en Sídney) estamos perdidos: estudio etnográfico de la satisfacción vital de aborígenes urbanos australianos participantes en un programa sociocomunitario / Here (in Sydney) we are lost: An ethnographic study of life satisfaction among urban aboriginal Australians participating in a community outreach program

RESUMEN Este estudio etnográfico fue diseñado para explorar las condiciones de vida de un grupo de familias aborígenes residentes en un contexto urbano, beneficiarias de un programa sociorecreativo en Sídney, Australia. El objetivo fue explorar la satisfacción vital mediante el análisis de sus condiciones de vida y del capital cultural inscrito en sus actitudes, percepciones y conocimientos establecidos. El trabajo de campo se estructuró en dos fases complementarias: en la fase 1, entre mayo de 2008 y diciembre de 2010, se inició con el ingreso del primer autor como voluntario en la asociación responsable del programa y, en la fase 2, entre enero de 2011 y febrero de 2013 se intensificó el proceso de observación participante y las entrevistas semiestructuradas. Los resultados muestran que el proceso de desarraigo cultural está en la base de las experiencias vitales de desigualdad social experimentadas y apunta a un efecto de cohorte que llega hasta nuestros días. Dicho proceso de (des)consonancia cultural debe ser tenido en cuenta como un factor clave a la hora de analizar las condiciones de vida y bienestar de estas minorías étnicas, así como a la hora de desarrollar programas e intervenciones.

ABSTRACT This ethnographic study was designed to explore living conditions among a group of aboriginal families residing in an urban context, who participated in a recreational social program. The aim of the study was to explore life satisfaction by analyzing their living conditions and cultural capital inscribed in established attitudes, perceptions, and lay knowledge. Fieldwork was carried out in two complementary phases: phase 1, between May 2008 and December 2010, began when the first listed author initiated volunteer work with the organization responsible for the program; in phase 2, which extended from January 2011 to February 2013, participant observation was intensified and semi-structured interviews were carried out. The results indicate that the process of cultural uprooting underscores the experience of social inequality, and suggest a cohort effect that continues to this day. This process of cultural (in)consonance must be taken into account as a key factor when analyzing the living conditions and well-being of ethnic minorities, as well as when developing programs and interventions.

COVID-19-Related Challenges in Dental Education: Experiences From Brazil, the USA, and Australia

Abstract Objective: To describe and compare how three dental schools from different countries (Australia, Brazil, and the USA) have managed experiences in dental education during the COVID-19 crisis. Material and Methods: It is a descriptive study reporting the experience that three distinct dental schools faced during the COVID-19 pandemic. They represent countries that adopted different measures to tackle the pandemic and were undergoing different stages of the disease. Results: After the WHO declared the COVID-19 pandemic, the Federal University of Paraíba suspended all on-site teaching, research, and service activities. For the return to teaching activities, the use of information and communications technology resources for distance learning was recommended. At the School of Dental Medicine (University of Pittsburgh), all research activities were suspended or, otherwise, could not be interrupted because of the employment of unique materials or supplies. When the pandemic started, Australia was one of the first countries to introduce strong regulations related to social distancing, travel restrictions, testing and tracking of infected patients. As such, the universities started to be closed from mid-March, cancelling all clinical and pre-clinical activities, maintaining online theoretical activities, such as seminars, lectures, and journal clubs. Conclusion: Numerous and critical difficulties have arisen as a result of the pandemic for individuals, communities and institutions that will have long-lasting effects. Our students face disruption to their education and career; our professional colleagues will be challenged rebuilding their practices, while staff at all Dental Schools are experiencing various hardships.

Equivalencia cultural de la versión Chilena del Evaluation of Ability to Sing Easily: EASE / Cross-cultural adaptation of the Chilean version of Evaluation of Ability to Sing Easily: EASE

RESUMEN Objetivo: Adaptar lingüística y culturalmente el protocolo australiano de voz cantada Evaluation of Ability to Sing Easily (EASE) al español chileno. Método: Fue realizada la traducción al español chileno del EASE y posteriormente la retrotraducción; ambas fueron revisadas por un comité compuesto por 4 fonoaudiólogos quienes crearon la primera versión en español chileno (EASE-CL). El EASE-CL está compuesto, al igual que el original, por 22 ítems que se contestan de acuerdo con una escala de Likert de frecuencia, a la que, durante la adaptación, se le sumó la alternativa "no aplicable" para poder identificar las consignas no comprendidas o inapropiadas para el vocabulario de los cantantes chilenos. Esta versión se aplicó a 21 cantantes profesionales de la región de Valparaíso. Durante esta aplicación no existieron sugerencias para el cambio de alguna consigna. Resultado: El EASE-CL refleja la versión original del inglés, tanto en la cantidad de ítems como en dominios. Conclusión: Queda demostrada la equivalencia cultural y lingüística del protocolo EASE al español chileno, originándose la versión EASE-CL.

ABSTRACT Purpose: To adapt the Australian singing voice protocol, Evaluation of Ability to Sing Easily (EASE) to Chilean Spanish. Methods: A translation of the EASE to Chilean Spanish was performed and later back translated; these were reviewed by a committee made up of 4 Speech-Language pathologists who created the first version in Chilean Spanish (EASE-CL). The EASE-CL is made up of 22 items, the same as the original, which are answered according to a Likert frequency scale, to which, during its adaptation, the option 'not applicable' was added in order to identify the instructions that were not understood or inappropriate for the vocabulary of Chilean singers. This version was applied to 21 professional singers in the Valparaiso Region. During this application there were no suggestions to change any of the instructions. Results: The EASE-CL reflects the original English both in the number of items and in the domains. Conclusion: The cultural and linguistic equivalence of the EASE protocol in Chilean Spanish was demonstrated and the EASE-CL version came to be.

O acesso a medicamentos em sistemas universais de saúde - perspectivas e desafios / Access to medication in universal health systems - perspectives and challenges

RESUMO Este estudo objetivou analisar os desafios do acesso a medicamentos em quatro sistemas universais de saúde da Austrália, do Brasil, do Canadá e do Reino Unido. Estudo qualitativo crítico-reflexivo por meio de revisão integrativa da literatura. Um dos grandes desafios dos sistemas estudados é o da incorporação de medicamentos de alto custo, via análises de custo-efetividade para cumprir a difícil tarefa de conciliar a justiça social e a equidade no acesso com sustentabilidade econômica. Particularmente o Canadá, mesmo sendo um país desenvolvido, ainda vive o dilema de como financiar um sistema de saúde no qual o acesso a medicamentos também seja universal. O Brasil convive com duas realidades problemáticas: primeiro, dar acesso a medicamentos, já padronizados pelo Sistema Único de Saúde (SUS), diante de um financiamento diminuto, segundo, de maneira semelhante aos sistemas australiano, canadense e inglês, vive o dilema de como incorporar novos medicamentos eficazes e com viabilidade econômica, além da questão da judicialização da saúde, um fenômeno complexo resultante da fragilidade pública na organização, financiamento, consolidação do SUS.

ABSTRACT This study aimed to analyze the challenges of access to medicines in four universal health systems in Australia, Brazil, Canada and the United Kingdom. Critical-reflexive qualitative study through Integrative Literature Review. The great challenge of the systems studied is the incorporation of high-cost drugs, through cost-effectiveness analyses to fulfill the difficult task of reconciling social justice and access equity with economic sustainability. Canada, in particular, despite being a developed country, still deals with the dilemma of how to finance a health system in which access to medicines is also universal. Brazil deals with two problematic realities: first, to grant access to medicines that are already standardized by the Unified Health System (SUS), in the face of insufficient funding. Secondly, similarly to the Australian, Canadian, and English systems, the dilemma of how to incorporate new efficient medicines considering its economic feasibility, as well as the issue of health judicialization, a complex phenomenon resulting from public fragility in the organization, financing, and consolidation of the SUS.

Factors associated with self-reported dental visits among older melbournians: the MELSHA study 2008 data collection / Factores asociados con visitas dentales autoinformadas entre melbournianos mayores: el estudio MELSHA 2008 recopilación de datos

Objective: To describe self-reported oral health-care visits and associated factors in older adults in Melbourne, Australia. Material and Methods: 201 older adults, 79-96 years, took part in the Melbourne Longitudinal Studies on Healthy Ageing (MELSHA) in 2008. Participants who visited a dentist within 12-months prior were identified. Logistic regression examined factors associated with the 12-month visits. Results: 47.7% reported visits to the dentist in the previous 12 months. Multivariate analyses showed dentate participants (OR=11.27; 95% CI: 4.38-29.00) were more likely to have a 12-month visit, and; those receiving a government pension or benefit were less likely to have a 12-month visit (OR=0.38; 95% CI 0.18-0.79). Conclusion: Compared with existing data on the oral health of older Australians, MELSHA participants appear to have lower dental attendance. Findings highlight the need to increase older people sl eeking oral health-care, and the need to collect information to identify influencers of oral health service usage.

Objetivo: Describir las visitas de atención de salud bucal autoreportadas y los factores asociados en adultos mayores en Melbourne, Australia. Métodos: 201 adultos mayores, de 79 a 96 años, participaron en los Estudios longitudinales de Envejecimiento Saludable en Melbourne (MELSHA) en 2008. Se identificaron los participantes que visitaron a un dentista dentro de los 12 meses anteriores. La regresión logística examinó los factores asociados con haber visitado el dentists en los ultimos 12 meses. Resultados: el 47,7% informó visitas al dentista en los 12 meses anteriores. Los análisis multivariados mostraron que los participantes dentados (OR=11.27; IC 95%:4.38-29.00) tenían más probabilidades de haber visitado al dentista en los ultimos 12 meses; y aquellos que recibieron una pensión o beneficio del gobierno tenían menos probabilidades de haber reportado una visita en los ultimos 12 meses (OR=0,38; IC del 95%:0,18 a 0,79). Conclusión: en comparación con los datos existentes sobre la salud oral de los australianos adultos mayores, los participantes de MELSHA reportaron una menor asistencia dental. Los resultados resaltan la necesidad de aumentar que adultos mayores busquen atención de salud bucal, y la necesidad de recopilar información para identificar influyentes en el uso de servicios de salud bucal.

Efficacy of adjunctive Garcinia mangostana Linn (mangosteen) pericarp for bipolar depression: study protocol for a proof-of-concept trial

Objective: Bipolar depression is characterized by neurobiological features including perturbed oxidative biology, reduction in antioxidant levels, and a concomitant rise in oxidative stress markers. Bipolar depression manifests systemic inflammation, mitochondrial dysfunction, and changes in brain growth factors. The depressive phase of the disorder is the most common and responds the least to conventional treatments. Garcinia mangostana Linn, commonly known as mangosteen, is a tropical fruit. The pericarp's properties may reduce oxidative stress and inflammation and improve neurogenesis, making mangosteen pericarp a promising add-on therapy for bipolar depression. Methods: Participants will receive 24 weeks of either 1,000 mg mangosteen pericarp or placebo per day, in addition to their usual treatment. The primary outcome is change in severity of mood symptoms, measured using the Montgomery-Åsberg Depression Rating Scale (MADRS), over the treatment phase. Secondary outcomes include global psychopathology, quality of life, functioning, substance use, cognition, safety, biological data, and cost-effectiveness. A follow-up interview will be conducted 4 weeks post-treatment. Conclusion: The findings of this study may have implications for improving treatment outcomes for those with bipolar disorder and may contribute to our understanding of the pathophysiology of bipolar depression. Clinical trial registration: Australian and New Zealand Clinical Trial Registry, ACTRN12616000028404.

Australian osteopathic practitioners' perceptions of the clinical relevance of anatomy / Percepciones de los practicantes de osteopatía australianos de la relevancia clínica de la anatomía

SUMMARY: Anatomy is a foundational discipline in the training of health care professionals. However, there is a paucity of literature on the relative importance of anatomy, especially in relation to the other biomedical sciences and clinical domains, in preparing osteopathic practitioners for clinical practice. This study aimed to examine Australian osteopathic practitioners' perceptions of the relative importance of anatomy in their professional training and clinical practice, especially in relation to other biomedical sciences and clinical domains within osteopathic curricula. The study also examined the perceived importance of the sub-disciplines of anatomy to professional practice. A questionnaire-based survey was carried out among Australian osteopathic practitioners at several national meetings in 2014 and 2015. Using a five-point Likert scale, all respondents were asked to rate the relevance of the following thirteen disciplines and subdisciplines to clinical practice: biomechanics, biochemistry, embryology, histology, gross anatomy, microbiology, neuroanatomy, neurology, pathology, pharmacology, physical examination, physiology and radiology. Out of 175 practitioners surveyed, 169 responded (i.e., 96.6 % response rate). Two of the sub-disciplines of anatomy were among the highest rated, with 98.2 % perceiving gross anatomy as "very important" while neuroanatomy being rated as "very important" by 84.6 % and "quite important" by 14.2 %. Similar high rating was also given to biomechanics and physical examination while the other two sub-disciplines, embryology and histology received lower ratings. No significant difference in ratings were identified with regard to participants' year and place of graduation. However, there was an association between gender and rating on Pathology and Pharmacology respectively, as well as age effects on the ratings of several sub-disciplines. These findings are generally consistent with the results from similar surveys carried out on the clinical importance of anatomy in other medical and allied health professionals in different countries. Overall, osteopathic practitioners have a positive perception of the relevance of anatomy, particularly gross and neuroanatomy, to clinical practice, and this should be taken into account when developing osteopathic curricula.

RESUMEN: La anatomía es una disciplina fundamental en la formación de profesionales de la salud. Sin embargo, hay poca literatura sobre la importancia relativa de la anatomía, especialmente en relación con las otras ciencias biomédicas y los dominios clínicos, en la preparación de profesionales de la osteopatía para la práctica clínica. Este estudio tuvo como objetivo examinar las percepciones de los médicos osteopáticos australianos sobre la importancia relativa de la anatomía en su formación profesional y práctica clínica, especialmente en relación con otras ciencias biomédicas y dominios clínicos dentro de los currículos osteopáticos. El estudio también examinó la importancia percibida de las subdisciplinas de la anatomía para la práctica profesional. Se realizó una encuesta basada en un cuestionario entre los profesionales osteopáticos australianos en varias reuniones nacionales en 2014 y 2015. Utilizando una escala Likert de cinco puntos, se pidió a todos los encuestados que calificaran la relevancia de las siguientes trece disciplinas y subdisciplinas para la práctica clínica: Biomecánica, bioquímica, embriología, histología, anatomía macroscópica, microbiología, neuroanatomía, neurología, patología, farmacología, exploración física, fisiología y radiología. De los 175 practicantes encuestados, 169 respondieron (es decir, una tasa de respuesta del 96,6 %). Dos de las subdisciplinas de la anatomía estaban entre las mejor calificadas, con un 98,2 % que percibían la anatomía general como "muy importante", mientras que la neuroanatomía se calificaba como "muy importante" en un 84,6 % y "muy importante" en un 14,2 %. También se dio una calificación alta similar a la biomecánica y el examen físico, mientras que las otras dos subdisciplinas, embriología e histología recibieron calificaciones más bajas. No se identificaron diferencias significativas en las calificaciones con respecto al año de los participantes y el lugar de graduación. Sin embargo, hubo una asociación entre el sexo y la calificación en Patología y Farmacología respectivamente, así como los efectos de la edad en las calificaciones de varias subdisciplinas. Estos hallazgos son generalmente consistentes con los resultados de encuestas similares realizadas sobre la importancia clínica de la anatomía, en otros profesionales de la salud médicos y afines en diferentes países. En general, los profesionales de la osteopatía tienen una percepción positiva de la relevancia de la anatomía, en particular la neuroanatomía general y la neuroanatomía, para la práctica clínica, lo que se debe tener en cuenta al desarrollar los currículos osteopáticos.