The mosaic structure of the mammalian cognitive map.

The cognitive map, proposed by Tolman in the 1940s, is a hypothetical internal representation of space constructed by the brain to enable an animal to undertake flexible spatial behaviors such as navigation. The subsequent discovery of place cells in the hippocampus of rats suggested that such a map-like representation does exist, and also provided a tool with which to explore its properties. Single-neuron studies in rodents conducted in small singular spaces have suggested that the map is founded on a metric framework, preserving distances and directions in an abstract representational format. An open question is whether this metric structure pertains over extended, often complexly structured real-world space. The data reviewed here suggest that this is not the case. The emerging picture is that instead of being a single, unified construct, the map is a mosaic of fragments that are heterogeneous, variably metric, multiply scaled, and sometimes laid on top of each other. Important organizing factors within and between fragments include boundaries, context, compass direction, and gravity. The map functions not to provide a comprehensive and precise rendering of the environment but rather to support adaptive behavior, tailored to the species and situation.

Lateral entorhinal cortex subpopulations represent experiential epochs surrounding reward.

During goal-directed navigation, 'what' information, describing the experiences occurring in periods surrounding a reward, can be combined with spatial 'where' information to guide behavior and form episodic memories. This integrative process likely occurs in the hippocampus, which receives spatial information from the medial entorhinal cortex; however, the source of the 'what' information is largely unknown. Here, we show that mouse lateral entorhinal cortex (LEC) represents key experiential epochs during reward-based navigation tasks. We discover separate populations of neurons that signal goal approach and goal departure and a third population signaling reward consumption. When reward location is moved, these populations immediately shift their respective representations of each experiential epoch relative to reward, while optogenetic inhibition of LEC disrupts learning the new reward location. Therefore, the LEC contains a stable code of experiential epochs surrounding and including reward consumption, providing reward-centric information to contextualize the spatial information carried by the medial entorhinal cortex.

Commercial hatchery practices have long-lasting effects on laying hens' spatial behaviour and health.

The commercial hatchery process is globally standardized and exposes billions of day-old layer chicks to stress every year. By alleviating this early stress, on-farm hatching is thought to improve animal welfare, yet little is known about its effects throughout production. This study compared welfare indicators and spatial behaviours during the laying period of hens hatched in an on-farm environment (OFH) to those hatched in a commercial hatchery and transferred at one day-old to a rearing barn (STAN). In particular, we assessed how OFH and TRAN hens differed in space-use and movement behaviours following the transfer to the laying barn at 17 weeks of age, a similar stressor encountered by STAN hens early in life, and determined whether effects aligned more with the 'silver-spoon' or 'environmental matching' hypothesis. We found that for the first three months post-transfer into the laying barn, OFH hens, on average, transitioned less between the aviary's tiers and spent less time on the littered floor. Because OFH hens became behaviourally more similar to STAN hens over time, these results suggest that OFH hens required a prolonged period to establish their daily behavioural patterns. Furthermore, OFH hens had more severe keel bone fractures throughout the laying period but similar feather damage and body mass to STAN hens. No differences were found in hen mortality or the number of eggs per live hen. These findings support the environmental matching hypothesis and suggest that early-life stressors may have prepared hens for later-life stressors, underscoring the importance of both early-life and adult environments in enhancing animal welfare throughout production.

Atlantic cod individual spatial behaviour and stable isotope associations in a no-take marine reserve.

Foraging is a behavioural process and, therefore, individual behaviour and diet are theorized to covary. However, few comparisons of individual behaviour type and diet exist in the wild. We tested whether behaviour type and diet covary in a protected population of Atlantic cod, Gadus morhua. Working in a no-take marine reserve, we could collect data on natural behavioural variation and diet choice with minimal anthropogenic disturbance. We inferred behaviour using acoustic telemetry and diet from stable isotope compositions (expressed as δ13 C and δ15 N values). We further investigated whether behaviour and diet could have survival costs. We found cod with shorter diel vertical migration distances fed at higher trophic levels. Cod δ13 C and δ15 N values scaled positively with body size. Neither behaviour nor diet predicted survival, indicating phenotypic diversity is maintained without survival costs for cod in a protected ecosystem. The links between diet and diel vertical migration highlight that future work is needed to understand whether the shifts in this behaviour during environmental change (e.g. fishing or climate), could lead to trophic cascades.

Hippocampal representation during collective spatial behaviour in bats.

Social animals live and move through spaces shaped by the presence, motion and sensory cues of multiple other individuals1-6. Neural activity in the hippocampus is known to reflect spatial behaviour7-9 yet its study is lacking in such dynamic group settings, which are ubiquitous in natural environments. Here we studied hippocampal activity in groups of bats engaged in collective spatial behaviour. We find that, under spontaneous conditions, a robust spatial structure emerges at the group level whereby behaviour is anchored to specific locations, movement patterns and individual social preferences. Using wireless electrophysiological recordings from both stationary and flying bats, we find that many hippocampal neurons are tuned to key features of group dynamics. These include the presence or absence of a conspecific, but not typically of an object, at landing sites, shared spatial locations, individual identities and sensory signals that are broadcasted in the group setting. Finally, using wireless calcium imaging, we find that social responses are anatomically distributed and robustly represented at the population level. Combined, our findings reveal that hippocampal activity contains a rich representation of naturally emerging spatial behaviours in animal groups that could in turn support the complex feat of collective behaviour.

Spatial behavior of hepatitis A, MMR, and varicella vaccination coverage in the state of Minas Gerais, 2020.

OBJECTIVE: To analyze the spatial behavior of hepatitis A, measles, mumps, and rubella (MMR), and varicella vaccination coverage in children and its relationship with socioeconomic determinants in the state of Minas Gerais. METHODS: This ecological study investigated records of doses administered to children, extracted from the Immunization Information System of 853 municipalities in Minas Gerais, in 2020. We analyzed the vaccination coverage and socioeconomic factors. Spatial scan statistics were used to identify spatial clusters and measure the relative risk based on the vaccination coverage indicator and the Bivariate Moran Index, and thus detect socioeconomic factors correlated with the spatial distribution of vaccination. We used the cartographic base of the state and its municipalities and the ArcGIS and SPSS software programs. RESULTS: Hepatitis A (89.0%), MMR (75.7%), and varicella (89.0%) showed low vaccination coverage. All vaccines analyzed had significant clusters. The clusters most likely to vaccinate their population were mainly located in the Central, Midwest, South Central, and Northwest regions, while the least likely were in the North, Northeast, and Triângulo do Sul regions. The municipal human development index, urbanization rate, and gross domestic product were spatially dependent on vaccination coverage. CONCLUSIONS: The spatial behavior of hepatitis A, MMR, and varicella vaccination coverage is heterogeneous and associated with socioeconomic factors. We emphasize that vaccination records require attention and should be continuously monitored to improve the quality of information used in services and research.

Challenging Behavior in Context: A Case Study on How People, Space, and Activities Interact.

AIM: We aim to gain insight into the interaction between challenging behavior as shown by individuals with an intellectual impairment, and space, and to explore the possibilities of using routinely collected data to this end. BACKGROUND: Research on challenging behavior shown by intellectually impaired individuals links their behavior to context, which includes space. Unfortunately, research about this link is hard to conduct, since these individuals may have difficulties expressing themselves verbally and react extremely to sensory stimuli. METHOD: We conducted a single-case study, focusing on a Dutch very-intensive care facility. We analyzed data routinely collected by the healthcare organization in search of time-space configurations that provide insights into the resident-space interaction. As sensitizing concepts, we used three different contexts the residents interact with-space, people, and activities. FINDINGS: The study exemplified reported interactions that were direct, for example, between the residents and the spatial context, and indirect, for example, through other contexts (people and activities). Space impacts on residents' senses intensely and acts as a lightning rod for their perceived stress. People also influence residents substantially. Caregivers may both have positive or adverse effects, for example, absenteeism or schedule change. Co-residents may trigger challenging behavior directly by a mere presence or transfer of their stress. Transitions between activities cause unpredictability and are triggers for residents, which interact with space. CONCLUSIONS: Living environments providing choice in nearness to the caregiver and distance to co-residents "high in tension," lowering thresholds for transitions, and facilitating predictability would be beneficial for intellectually impaired individuals showing challenging behavior.

A map of spatial navigation for neuroscience.

Spatial navigation has received much attention from neuroscientists, leading to the identification of key brain areas and the discovery of numerous spatially selective cells. Despite this progress, our understanding of how the pieces fit together to drive behavior is generally lacking. We argue that this is partly caused by insufficient communication between behavioral and neuroscientific researchers. This has led the latter to under-appreciate the relevance and complexity of spatial behavior, and to focus too narrowly on characterizing neural representations of space-disconnected from the computations these representations are meant to enable. We therefore propose a taxonomy of navigation processes in mammals that can serve as a common framework for structuring and facilitating interdisciplinary research in the field. Using the taxonomy as a guide, we review behavioral and neural studies of spatial navigation. In doing so, we validate the taxonomy and showcase its usefulness in identifying potential issues with common experimental approaches, designing experiments that adequately target particular behaviors, correctly interpreting neural activity, and pointing to new avenues of research.

Understanding systemic racism: Anti-Blackness, white supremacy, racial capitalism, and the re/creation of white space and time.

In this article, the authors explain systemic racism through a racial-spatial framework wherein anti-Blackness, white supremacy, and racial capitalism interlock to create and recreate white space and time. Through the creation of private property, institutional inequities become embedded and structured for the benefit of white people. The framework provides a way to conceptualize how our geographies are racialized and how time is often used against Black and non-Black people of Color. In contrast to white experiences of feeling "in-place" almost everywhere, Black and non-Black people of Color continually experience displacement and dispossession of both their place and their time. This racial-spatial onto-epistemology is derived from the knowledge and experiences of Black, Indigenous, Latinx, Asian, and other non-Black people of Color, and how they have learned through acculturation, racial trauma, and micro-aggressions to thrive in white spaces and contend with racism such as time-theft. The authors posit that through reclaiming space and time, Black and non-Black people of Color can imagine and practice possibilities that center their lived experiences and knowledge as well as elevate their communities. Recognizing the importance of reclaiming space and time, the authors encourage counseling psychology researchers, educators, and practitioners to consider their positionalities with respect to systemic racism and the advantages it confers to white people. Through the process of creating counterspaces and using counterstorytelling, practitioners may help clients develop healing and nurturing ecologies that challenge the perniciousness of systemic racism. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Choice between decision-making strategies in human route-following.

To follow a prescribed route, we must decide which way to turn at intersections. To do so, we can memorize either the serial order of directions or the associations between spatial cues and directions ("at the drug store, turn left"). Here, we investigate which of these two strategies is used if both are available. In Task S, all intersections looked exactly alike, and participants therefore had to use the serial order strategy to decide which way their route continued. In Task SA, each intersection displayed a unique spatial cue, and participants therefore could use either strategy. In Task A, each intersection displayed a unique cue, but the serial order of cues varied between trips, and participants therefore had to use the associative cue strategy. We found that route-following accuracy increased from trip to trip, was higher on routes with 12 rather than 18 intersections, and was higher on Task SA than on the other two tasks, both with 12 and with 18 intersections. Furthermore, participants on Task SA acquired substantial knowledge about the serial order of directions as well as about cue-direction associations, both with 12 and with 18 intersections. From this we conclude that, when both strategies were available, participants did not pick the better one but rather used both. This represents dual encoding, a phenomenon previously described for more elementary memory tasks. We further conclude that dual encoding may be implemented even if the memory load is not very high (i.e., even with only 12 intersections).

Entropy and a sub-group of geometric measures of paths predict the navigability of an environment.

Despite extensive research on navigation, it remains unclear which features of an environment predict how difficult it will be to navigate. We analysed 478,170 trajectories from 10,626 participants who navigated 45 virtual environments in the research app-based game Sea Hero Quest. Virtual environments were designed to vary in a range of properties such as their layout, number of goals, visibility (varying fog) and map condition. We calculated 58 spatial measures grouped into four families: task-specific metrics, space syntax configurational metrics, space syntax geometric metrics, and general geometric metrics. We used Lasso, a variable selection method, to select the most predictive measures of navigation difficulty. Geometric features such as entropy, area of navigable space, number of rings and closeness centrality of path networks were among the most significant factors determining the navigational difficulty. By contrast a range of other measures did not predict difficulty, including measures of intelligibility. Unsurprisingly, other task-specific features (e.g. number of destinations) and fog also predicted navigation difficulty. These findings have implications for the study of spatial behaviour in ecological settings, as well as predicting human movements in different settings, such as complex buildings and transport networks and may aid the design of more navigable environments.

Pausing and reorienting behaviors enhance the performance of a spatial working memory task.

During spatial working memory tasks, animals need to retain information about a previous trial in order to successfully select their next trajectory. Specifically, the delayed non-match to position task requires rats to follow a cued sample trajectory, then select the opposite route after a delay period. When faced with this choice, rats will occasionally exhibit complex behaviors, such as pausing and sweeping their head back and forth. These behaviors, called vicarious trial and error (VTE), are thought to be a behavioral manifestation of deliberation. However, we identified similarly complex behaviors during sample-phase traversals, despite the fact that these laps do not require a decision. First, we identified that these behaviors occurred more often after incorrect trials than before them, indicating that rats are retaining information between trials. Next, we determined that these pause-and-reorient (PAR) behaviors increased the likelihood of the next choice being selected correctly, suggesting that these behaviors assist the rat in successful task performance. Finally, we identified similarities between PARs and choice-phase VTEs, suggesting that VTEs may not only be reflective of deliberation, but may also contribute to a strategy for successful performance of spatial working memory tasks.

Landscape Aesthetic Value of Waterfront Green Space Based on Space-Psychology-Behavior Dimension: A Case Study along Qiantang River (Hangzhou Section).

As an important part of urban green infrastructure, the landscape effect of the urban waterfront green space varies, and sometimes, the green space with an excellent landscape aesthetic value fails to serve the needs of most citizens. This seriously affects the construction of a green ecological civilization and the implementation of the concept of "common prosperity" in China. Based on multi-source data, this study took the Qiantang River Basin as an example, selected 12 representative waterfront green spaces along the river as the research objects, and used qualitative and quantitative analysis methods to determine the landscape aesthetic value of the research area from the different dimensions of space, psychology, and physiology. We examined the relationship between each dimension so as to objectively and comprehensively reflect the landscape value characteristics of the waterfront green space in the study area and provide a reasonable theoretical framework and practical development path for future urban waterfront green space landscape design. We obtained the following results: (1) The results of the spatial dimension research indicated that the spatial value index of the waterfront green space in the study area was three-dimensional space > vertical space > horizontal space, and the overall spatial value was low; Qianjiang Ecological Park obtained the highest value (0.5473), and Urban Balcony Park obtained the lowest value (0.4619). (2) The results of the psychological dimension indicated that people's perceptions of the waterfront green space in the study area were relatively weak, mainly focusing on visual perception, but the waterfront green space with a relative emotional value greater than one accounted for 75%, and the overall recognition of the landscape was high. (3) The results of the behavioral dimension showed that the overall heat of the waterfront green space in the study area was insufficient (1.3719-7.1583), which was mainly concentrated in low-heat levels, and the population density was unevenly distributed (0.0014-0.0663), which was mainly concentrated in the medium-density level. The main purpose of users was to visit, and they stayed an average of 1.5 h. (4) The results of the coupling coordination analysis of the spatial-psychological-behavioral dimensions showed that the landscape value of the waterfront green space in the study area presented a form of 'high coupling degree and low coordination degree'.

Behavioural ecology at the spatial-social interface.

Spatial and social behaviour are fundamental aspects of an animal's biology, and their social and spatial environments are indelibly linked through mutual causes and shared consequences. We define the 'spatial-social interface' as intersection of social and spatial aspects of individuals' phenotypes and environments. Behavioural variation at the spatial-social interface has implications for ecological and evolutionary processes including pathogen transmission, population dynamics, and the evolution of social systems. We link spatial and social processes through a foundation of shared theory, vocabulary, and methods. We provide examples and future directions for the integration of spatial and social behaviour and environments. We introduce key concepts and approaches that either implicitly or explicitly integrate social and spatial processes, for example, graph theory, density-dependent habitat selection, and niche specialization. Finally, we discuss how movement ecology helps link the spatial-social interface. Our review integrates social and spatial behavioural ecology and identifies testable hypotheses at the spatial-social interface.

Evaluating the effects of a programming error on a virtual environment measure of spatial navigation behavior.

Relying on shared tasks and stimuli to conduct research can enhance the replicability of findings and allow a community of researchers to collect large data sets across multiple experiments. This approach is particularly relevant for experiments in spatial navigation, which often require the development of unfamiliar large-scale virtual environments to test participants. One challenge with shared platforms is that undetected technical errors, rather than being restricted to individual studies, become pervasive across many studies. Here, we discuss the discovery of a software bug in a virtual environment platform used to investigate individual differences in spatial navigation: Virtual Silcton. The bug, which was difficult to detect for several reasons, resulted in storing the absolute value of a direction in a pointing task rather than the signed direction and rendered the original sign of the direction unrecoverable. To assess the impact of the bug on published findings, we collected a new data set for comparison. Results revealed that although the bug caused suppression in pointing errors and had different effects across people (less accurate navigators had more suppression), the effect of the bug on published data is small, partially explaining the difficulty in detecting the bug. We also used the new data set to develop a tool that allows researchers who have previously used Virtual Silcton to evaluate the impact of the bug on their findings. We summarize the ways that shared open materials, shared data, and collaboration can pave the way for better science to prevent errors in the future. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Larger on the right: Honeybees represent quantities spatially.

Giurfa, Marcout, Hilpert, Thevenoy, and Rugani (PNAS, https://doi.org/10.1073/pnas.22035841192022 ) report the first evidence of spatial representation of quantity in invertebrates. In an exciting and well-controlled series of experiments, the authors present evidence that honeybees, like humans, non-human primates, and birds, represent small quantities on one side of space and large quantities on the other side of space.

A small step for rats alters spatial behavior: rats on a bi-level arena explore each level separately.

We tested rats on a 'bi-level open-field' whose two halves were separated vertically by an 8-cm step that the rats could easily ascend/descend. We sought to determine what might be the factors that shape traveling in three-dimensional environments; what makes an environment perceived as multileveled; and how are multileveled environments explored compared to two-dimensional environments? We found that rats on the bi-level open-field traveled a greater distance on the lower level compared to the upper one. They also spent a long time at the foot of the step before ascending to the upper level. They established a home-base on one level and a local base on the other one, and explored each level separately. We could not find a particular factor that accounted for the preference for the lower level. We suggest that the momentary egocentric sensation of moving vertically, together with an overall area large enough for exploration, result in perceiving an environment as multilevel. Exploration of such environments is fragmented, and each level is explored relatively independently, as has also been shown in other studies. Regarding the unanswered question of earlier studies concerning what integrates fragmented representations, this is the first study that suggests that in rats, and perhaps also in other rodent species, such integration is achieved by means of home-base behavior, resulting in the establishment of a single comprehensive representation of the multilevel environment.

Utilizing a Reconfigurable Maze System to Enhance the Reproducibility of Spatial Navigation Tests in Rodents.

Several maze shapes are used to test spatial navigation performance and behavioral phenotypes. Traditionally, each experiment requires a unique maze shape, thus requiring several separate mazes in different configurations. The maze geometry cannot be reconfigured in a single environment to accommodate scalability and reproducibility. The reconfigurable maze is a unique approach to address the limitations, allowing quick and flexible configurations of maze pathways in a repeatable manner. It consists of interlocking pathways and includes feeders, treadmills, movable walls, and shut-off sensors. The current protocol describes how the reconfigurable maze can replicate existing mazes, including the T-shaped, plus-shaped, W-shaped, and figure-eight mazes. Initially, the T-shaped maze was constructed inside a single experimental room, followed by modifications. The rapid and scalable protocol outlined herein demonstrates the flexibility of the reconfigurable maze, achieved through the addition of components and behavioral training phases in a stepwise manner. The reconfigurable maze systematically and precisely assesses the performance of multiple aspects of spatial navigation behavior.

Negative patterning in the spatial domain.

In three experiments, animals were required to learn about the presence or absence of a hidden platform in a swimming pool. This was determined with reference to different patterned landmarks. In Experiment 1, the presence of a spotted or a striped cue indicated the position of the platform, while the combination of patterns, a half-spotted and half-striped cue, predicted the absence of the goal (i.e., negative patterning). In Experiment 2 the task was redesigned to better represent a locale navigation task. Rats received the same discrimination task, but it took place in an equilateral triangle with landmarks positioned on the walls of the arena. The hidden platform (if present) was located in one corner of the triangle. Experiment 3 used a more complex negative patterning discrimination in the triangular swimming pool to help dissociate between the unique cue and configural associative learning theories. Experiment 1 and 2 provides the first instance of negative patterning in a spatial task, while Experiment 3 provides initial evidence that some rats may represent compound stimuli in a way explained by the unique cue theory of associative learning. This begins to elucidate the underlying of associate principles that guide learning in the spatial domain.

Let them go free: Spatial behaviour following the experimental release of hatchery-reared juveniles Sciaena umbra and Dentex dentex.

As marine stocks and biodiversity are rapidly declining, the release of hatchery-reared individuals into the wild is a species conservation measure aiming at replenishing stocks of freshwater, anadromous and marine fish species. The aim of this study is to assess for the first time the post-release exploration behaviours, survival and dispersal in the wild of released hatchery-reared juveniles of D. dentex and S. umbra. For this purpose, twenty fish from each species were tagged with acoustic transmitters and released in a marine no-take zone located in Corsica (France). Most individuals were considered alive until their last detection (95% of S. umbra and 74% of D. dentex detected individuals). Fish were detected within the receiver array on average up to 11.3 (± 20.7) and 10.3 (± 10.3) days after being released for juveniles of D. dentex and S.umbra, respectively. Dentex dentex juveniles dispersed mostly southward along the shore whereas S. umbra juveniles tended to disperse along the shore both northward and southward from the acoustic receiver array. Before their rapid dispersion (i.e. within a few days) outside the studied zone, juveniles of both species displayed increasing cumulative MCP areas and increased their vertical niche revealing their gradual coverage and exploration of deeper habitats in the area. The results from our study highlighted that hatchery-reared juveniles of both species did not settle inside the studied area but seemed to start to acclimate to the natural environment. This work is a first step towards the assessment of the viability of restocking for both species.