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1.
PLoS One ; 19(4): e0301868, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38603724

RESUMO

The role that inhaled particulate matter plays in the development of post-deployment lung disease among US service members deployed to Southwest Asia during the Global War on Terrorism has been difficult to define. There is a persistent gap in data addressing the relationship between relatively short-term (months to a few years) exposures to high levels of particulate matter during deployment and the subsequent development of adverse pulmonary outcomes. Surgical lung biopsies from deployed service members and veterans (DSMs) and non-deployed service members and veterans (NDSMs) who develop lung diseases can be analyzed to potentially identify residual deployment-specific particles and develop associations with pulmonary pathological diagnoses. We examined 52 surgical lung biopsies from 25 DSMs and 27 NDSMs using field emission scanning electron microscopy (FE-SEM) with energy dispersive x-ray spectroscopy (EDS) to identify any between-group differences in the number and composition of retained inorganic particles, then compared the particle analysis results with the original histopathologic diagnoses. We recorded a higher number of total particles in biopsies from DSMs than from NDSMs, and this difference was mainly accounted for by geologic clays (illite, kaolinite), feldspars, quartz/silica, and titanium-rich silicate mixtures. Biopsies from DSMs deployed to other Southwest Asia regions (SWA-Other) had higher particle counts than those from DSMs primarily deployed to Iraq or Afghanistan, due mainly to illite. Distinct deployment-specific particles were not identified. Particles did not qualitatively associate with country of deployment. The individual diagnoses of the DSMs and NDSMs were not associated with elevated levels of total particles, metals, cerium oxide, or titanium dioxide particles. These results support the examination of particle-related lung disease in DSMs in the context of comparison groups, such as NDSMs, to assist in determining the strength of associations between specific pulmonary pathology diagnoses and deployment-specific inorganic particulate matter exposure.


Assuntos
Pneumopatias , Militares , Minerais , Terrorismo , Humanos , Pulmão/patologia , Pneumopatias/patologia , Material Particulado , Biópsia
2.
PLoS One ; 19(3): e0295695, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38451934

RESUMO

This specific research initiative aims to intricately examine the intricate dynamics connecting terrorism, corruption, and capital flight within the context of South Asian economies, encompassing countries including Bangladesh, India, Pakistan, and Sri Lanka. The principal objectives of this study entail a comprehensive investigation into the synergistic impacts of terrorism and corruption on the prevalence of capital flight. To realize these objectives, the study employs longitudinal data from 1990 to 2019, adopting the portfolio choice framework as its theoretical underpinning. In terms of methodology, the empirical inquiry uses the Generalized Method of Moments (GMM) estimation technique. The empirical findings derived from this analysis distinctly establish a statistically noteworthy and positive correlation between terrorism, corruption, and the occurrence of capital flight across multiple South Asian nations. In light of these discerning outcomes, it is strongly recommended that the governments of South Asian countries prioritize and actively pursue the fortification of their institutional governance mechanisms. This strategic approach is deemed crucial in efficaciously counteracting the escalation of capital flight. Specifically, a targeted focus on augmenting institutional governance practices, fostering transparency, fortifying anti-corruption measures, and intensifying counterterrorism efforts could collectively contribute to reducing capital flight tendencies. By undertaking these recommendations, South Asian governments can foster an environment of enhanced economic stability, attractiveness for investment, and sustainable growth, thereby deterring the adverse impact of capital flight while concurrently combatting the underlying challenges posed by terrorism and corruption.


Assuntos
Governo , Terrorismo , Sri Lanka , Investimentos em Saúde , Índia , Desenvolvimento Econômico
3.
BMC Health Serv Res ; 24(1): 277, 2024 Mar 08.
Artigo em Inglês | MEDLINE | ID: mdl-38454472

RESUMO

BACKGROUND: There is scarce knowledge on the health care follow-up of parents of terror attack survivors. This study focused on the mothers and fathers of survivors and examined (1) their perceived health care needs relative to their psychological reactions, physical health problems (unmet health care needs), and adaptation to work; (2) whether sociodemographic characteristics, health problems and social support were associated with unmet health care needs; and (3) how unmet health care needs, sociodemographic characteristics, and experiences with health services associated with overall dissatisfaction during the health care follow-up. METHODS: Interview and questionnaire data from three waves of the Utøya parent study were analyzed (n = 364). Chi-square tests and t- tests were used to compare unmet physical and psychological health care needs, sociodemographic factors and post-terror attack health reported by mothers and fathers. Logistic regression analyses were used to examine whether sociodemographic characteristics, unmet health care needs, and health care experiences were associated with overall dissatisfaction among mothers and fathers of the survivors during the health care follow-up. RESULTS: Among the mothers, 43% reported unmet health care needs for psychological reactions, while 25% reported unmet health care needs for physical problems. Among the fathers, 36% reported unmet health care needs for psychological reactions, and 15% reported unmet health care needs for physical problems. Approximately 1 in 5 mothers and 1 in 10 fathers reported "very high/high" needs for adaptation to work. Poorer self-perceived health, higher levels of posttraumatic stress and anxiety/depression symptoms, and lower levels of social support were significantly associated with reported unmet psychological and physical health care needs in both mothers and fathers. Parents with unmet health care needs reported significantly lower satisfaction with the help services received compared to parents whose health care needs were met. Low accessibility of help services and not having enough time to talk and interact with health care practitioners were associated with overall dissatisfaction with the help received. CONCLUSIONS: Our findings highlight that parents of terror-exposed adolescents are at risk of having unmet psychological and physical health care needs and thus need to be included in proactive outreach and health care follow-up programs in the aftermath of a terror attack.


Assuntos
Transtornos de Estresse Pós-Traumáticos , Terrorismo , Feminino , Adolescente , Humanos , Estudos Longitudinais , Transtornos de Estresse Pós-Traumáticos/epidemiologia , Transtornos de Estresse Pós-Traumáticos/psicologia , Terrorismo/psicologia , Atenção à Saúde , Pais/psicologia , Sobreviventes/psicologia
4.
Front Public Health ; 12: 1362021, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38525333

RESUMO

Introduction: After the terrorist attacks, early psychosocial care is provided to people considered at risk of developing mental health issues due to the attacks. Despite the clear importance of such early intervention, there is very few data on how this is registered, who is targeted, and whether target-recipients accept such aid. Methods: Using registry data from the Centre General Wellbeingwork (CAW), a collection of centers in the regions Brussels and Flanders that provide psychosocial care, we examined the early psychosocial care response after the terrorist attacks of 22/03/2016 in Belgium. Results: In total, 327 people were listed to be contacted by the CAW, while only 205 were reached out to (62.7%). Most were contacted within a month (84.9%), and were victims of the attacks (69.8%). Overall, the majority was female (55.6%). Conclusion: Overall, target recipients were witnesses and survivors of the attacks, though a large proportion of people were not reached by the early outreach.


Assuntos
Terrorismo , Humanos , Feminino , Bélgica , Terrorismo/psicologia , Sobreviventes/psicologia
5.
PLoS One ; 19(2): e0293810, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38354207

RESUMO

Exposure to radicalizing information has been associated with support for violent extremism. It is, however, unclear whether specific information use behavior, namely, a distinct pattern of incidental exposure (IE) to and active selection (AS) of radicalizing content, indicates stronger violent extremist attitudes and radical action intentions. Drawing on a representative general population sample (N = 1509) and applying latent class analysis, we addressed this gap in the literature. Results highlighted six types of information use behavior. The largest group of participants reported a near to zero probability of both IE to and AS of radicalizing material. Two groups of participants were characterized by high or moderate probabilities of incidental exposure as well as a low probability of active selection of radicalizing content. The remaining groups displayed either low, moderate, or high probabilities of both IE and AS. Importantly, we showed between-group differences regarding violent extremist attitudes and radical behavioral intentions. Individuals reporting near zero or high probabilities for both IE to and AS of radicalizing information expressed the lowest and strongest violent extremist attitudes and willingness to use violence respectively. Groups defined by even moderate probabilities of AS endorsed violent extremism more strongly than those for which the probability for incidental exposure was moderate or high but AS of radicalizing content was unlikely.


Assuntos
Terrorismo , Humanos , Violência , Agressão , Intenção , Atitude
6.
Eur J Psychotraumatol ; 15(1): 2312750, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38386049

RESUMO

Background: The long-term impact of mass violence attacks is practically unknown, especially in children and adolescents. In a previous study, we found that 8.5 years after a terror attack targeting mainly adolescents, nearly half of the survivors met diagnostic criteria for insomnia.Objectives: The aims of this study were to investigate: (1) whether exposure to a single mass violence event during adolescence increases the risk of insomnia almost a decade later above that expected for a non-exposed population; and (2) whether prior interpersonal violence exposure and early post-traumatic reactions predict later insomnia.Method: Participants were survivors of the 2011 Utøya Island terrorist attack (n = 279) and controls from the HUNT Norwegian general population study (n = 35,664). Early adulthood insomnia was assessed using four items from the Karolinska Sleep Questionnaire 8.5 years after the attack. Participants who had also completed earlier data collection waves for both studies (n = 116 and 2382, respectively) were included in logistic regression models testing the associations between predictors during adolescence and later insomnia.Results: Nearly a decade after the Utøya attack, 38.4% (n = 56) of the survivors reported symptoms of insomnia indicative of probable insomnia compared to 20.5% (n = 5771) of controls. Terror exposure during adolescence was a significant predictor of later insomnia [odds ratio (OR) = 3.18, 95% confidence interval (CI) = 2.05-4.87, p < .001]. Early post-trauma symptoms of anxiety and depression (OR = 1.34, 95% CI = 1.02-1.76, p = .033) and weekly headaches (OR = 1.64, 95% CI = 1.08-2.47, p = .018) were also significant predictors while controlling for background factors and other predictors.Conclusion: Long-term assessment and treatment are needed for survivors of mass violence to improve resilience and recovery.


Nearly twice as many young adults exposed to a terror attack during adolescence report insomnia compared to a general population sample.Exposure to the attack and early post-trauma symptoms of anxiety, depression, and weekly headaches were significant predictors of insomnia around a decade later.Long-term assessment and treatment is needed for survivors of mass violence attacks.


Assuntos
Exposição à Violência , Distúrbios do Início e da Manutenção do Sono , Terrorismo , Criança , Humanos , Adolescente , Adulto , Distúrbios do Início e da Manutenção do Sono/epidemiologia , Seguimentos , Violência
7.
Prehosp Disaster Med ; 39(1): 65-72, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38204194

RESUMO

INTRODUCTION: Intentional mass-casualty incidents (IMCIs) involving motor vehicles (MVs) as weapons represent a growing trend in Western countries. This method has resulted in the highest casualty rates per incident within the field of IMCIs. Consequently, there is an urgent requirement for a timely and accurate casualty estimation in MV-induced IMCIs to scale and adjust the necessary health care resources. STUDY OBJECTIVE: The objective of this study is to identify the factors associated with the number of casualties during the initial phase of MV-IMCIs. METHODS: This is a retrospective, observational, analytical study on MV-IMCIs world-wide, from 2000-2021. Data were obtained from three different sources: Targeted Automobile Ramming Mass-Casualty Attacks (TARMAC) Attack Database, Global Terrorism Database (GTD), and the vehicle-ramming attack page from the Wikipedia website. Jacobs' formula was used to estimate the population density in the vehicle's route. The primary outcome variables were the total number of casualties (injured and fatalities). Associations between variables were analyzed using Spearman's correlation coefficient and simple linear regression. RESULTS: Forty-six MV-IMCIs resulted in 1,636 casualties (1,430 injured and 206 fatalities), most of them caused by cars. The most frequent driving pattern was accelerating whilst approaching the target, with an average speed range between four to 130km/h and a distance traveled between ten to 2,260 meters. The people estimated in the MV-IMCI scenes ranged from 36-245,717. A significant positive association was found of the number affected with the estimated crowd in the scene (R2: 0.64; 95% CI, 0.61-0.67; P <.001) and the average vehicle speed (R2: 0.42; 95% CI, 0.40-0.44; P = .004). CONCLUSION: The estimated number of people in the affected area and vehicle's average speed are the most significant variables associated with the number of casualties in MV-IMCIs, helping to enable a timely estimation of the casualties.


Assuntos
Planejamento em Desastres , Incidentes com Feridos em Massa , Terrorismo , Humanos , Triagem/métodos , Aglomeração , Veículos Automotores
8.
PLoS One ; 19(1): e0281615, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38252642

RESUMO

Terrorism has shown a trend of organizational cooperation in a large number of terrorist attacks around the world, posting a great challenge to counter-terrorism efforts. To investigate the trend and pattern of global terrorist organizational cooperations and to propose effective measures for effectively enforcing and restricting terrorist attacks, based on the Global Terrorism Database and the UN sanctions list of terrorist groups, this study constructs a cooperative evolutionary network of terrorist organizations from 119,803 terrorist attacks that occurred globally between 2001 and 2018. The evolution of worldwide terrorist cooperation is evaluated in terms of network characteristics, including key nodes, cohesion, and motifs. The network keeps expanding, with a large number of new nodes emerging each year. On average, there are 13 additional organizations entering in the collaboration network each year, with a yearly survival rate of about 34.66%, and the rank of node importance iterate and update frequently. Through k-core decomposition, for which the breakdown of the network has increased from three to five partitions, we find that the core of the terrorist organization's cooperation network changes much less frequently than the edges. The dominating modal structure of the network is the "star" motif (90%), and "triadic closed" motif (9%). We conclude that, over time, the cooperative network of terrorist groups has gradually evolved into a cluster of star-shaped networks, with various organizations serving as the centers of the networks and showing core-periphery structure in their individual communities. The core organizations are highly connected and stable, whereas the periphery organizations are loosely connected and highly variable.


Assuntos
Organizações , Terrorismo , Bases de Dados Factuais
9.
Disaster Med Public Health Prep ; 18: e12, 2024 Jan 30.
Artigo em Inglês | MEDLINE | ID: mdl-38287687

RESUMO

INTRODUCTION: Nightclubs are entertainment and hospitality venues historically vulnerable to terrorist attacks. This study identified and characterized terrorist attacks targeting nightclubs and discotheques documented in the Global Terrorism Database (GTD) over a 50-y period. METHODS: A search of the Global Terrorism Database (GTD) was conducted from 1970 to 2019. Precoded variables for target type "business" and target subtype "entertainment/cultural/stadium/casino" were used to identify attacks potentially involving nightclubs. Nightclub venues were specifically identified using the search terms "club," "nightclub," and "discotheque." Two authors manually reviewed each entry to confirm the appropriateness for inclusion. Descriptive statistics were performed using R (3.6.1). RESULTS: A total of 114 terrorist attacks targeting nightclub venues were identified from January 1, 1970, through December 31, 2019. Seventy-four (64.9%) attacks involved nightclubs, while forty (35.1%) attacks involved discotheques. A bombing or explosion was involved in 84 (73.7%) attacks, followed by armed assault in 14 (12.3%) attacks. The highest number of attacks occurred in Western Europe and Sub-Saharan Africa. In total, 284 persons died, and 1175 persons were wounded in attacks against nightclub venues. CONCLUSIONS: While terrorist attacks against nightclub venues are infrequent, the risk for mass casualties and injuries can be significant, mainly when explosives and armed assaults are used.


Assuntos
Incidentes com Feridos em Massa , Terrorismo , Humanos , Europa (Continente)
10.
Harefuah ; 163(1): 12-16, 2024 Jan.
Artigo em Hebraico | MEDLINE | ID: mdl-38297413

RESUMO

INTRODUCTION: A war usually requires a new or adjusted set up and needs of all caregivers according to the "new" status. The current war in Israel began on the 7.10.2023. The Israeli Ministries of Defense and Health were in a new status in which they had to complete new requirements according to the use of new weapons, and in numbers and types of injuries that overwhelmed the system from the day the war began. In the past, we published evidence that in times of terror, as in times of war, epidemiology of injuries changes and requires adjustments in human resources, surgical tools and consumables in the Israeli health and defense systems. This article aims to describe the role of specialists in plastic, aesthetic and reconstructive surgery and the first response according to the existing system divided into prevention, preparedness, response and rehabilitation. In the long term rapid response, recruitment of human resources, abilities and flexibility of the system enables overcoming a sudden "new" status as in war, terror and mass casualty events.


Assuntos
Procedimentos de Cirurgia Plástica , Cirurgia Plástica , Terrorismo , Humanos , Guerra , Israel/epidemiologia
11.
J Pharmacol Exp Ther ; 388(2): 260-267, 2024 01 17.
Artigo em Inglês | MEDLINE | ID: mdl-38233227

RESUMO

This Commentary delves into the current progress and challenges on ongoing research on medical countermeasures (MCs) for chemical, biologic, radiologic, and nuclear (CBRN) threats. CBRN agents pose a serious risk to human health and safety, with the potential for mass casualties in both military and civilian settings. Chemical threats are toxic compounds that could be used in a terrorist attack, an accidental release, or chemical warfare. They include nerve agents, organophosphates, pulmonary agents, metabolic/cellular agents, vesicants, ocular toxicants, and opioid agents. Developing effective MCs is crucial for mitigating the acute and chronic effects of exposure to CBRN agents. The papers in this special issue of JPET highlights the latest advancements in MC research, showcasing insightful outcomes on experimental models, mechanisms, and translational research on MCs for CBRN threats. They portray several notable contributions, including the development of neurosteroid and combination anticonvulsant therapies for nerve agent poisoning, the exploration of chronic impacts and diagnostic tracers for OP neurotoxicity, the establishment of innovative pediatric OP models, the identification of novel molecules for ocular, pulmonary and vesicant injuries, and the repurposing of existing drugs for the treatment of botulism, cyanide, and OP poisoning. These crucial outcomes underscore the breadth of current research covering a variety of chemical threats. Overall, this collection of articles highlights the importance of ongoing research and development in the field of MCs, emphasizing the potential of these countermeasures to effectively treat and mitigate the effects of toxicant exposures and thereby enhance our preparedness for mass casualty incidents. SIGNIFICANCE STATEMENT: CBRN agents pose a significant threat to public health. Effective MCs exist for certain chemical threats, but there is a need for new and improved MCs for many others. The research presented in this special issue of JPET highlights the latest advancements in MCs for CBRN threats. This research has the potential to lead to the development of new and repurposed MCs that are more effective, broad-spectrum, and easier to administer to mitigate acute and long-term consequences of chemical exposures.


Assuntos
Contramedidas Médicas , Terrorismo , Humanos , Criança
12.
Trauma Violence Abuse ; 25(2): 1184-1200, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-37272343

RESUMO

Given the pervasiveness of violent extremism all over the globe, understanding its psychological underpinnings is key in the fight against it. According to the Significance Quest Theory and its 3N model, violent extremism (i.e., violent and deviant behavior) is a function of three elements: need, narrative, and network. In the present meta-analysis, to put into test the theory and its model, we aimed to establish the strength of the association between these three elements, as well as the quest for significance itself, and violent extremism; and investigate if these associations are influenced by methodological decisions (i.e., sampling and measurements/manipulations). A literature search was performed through electronic platforms, a call for unpublished or in-press data, and backward snowballing. Seventeen reports, comprising 42 studies, met full inclusion criteria: quantitative studies based on primary data assessing for the association of at least one of the 3Ns, or quest for significance, and violent extremism, and providing sufficient data for effect size extraction. Findings are reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA) guidelines. Random-effect meta-analyses rendered statistically significant pooled effect sizes in all the investigated associations. The association is strong for quest for significance, moderate for narrative and network, and low for need for significance. Subgroup analyses demonstrate that the detection of these associations is influenced by methodological decisions concerning the measurements and manipulations, but not by those concerning the sampling. We discuss these findings and suggest future research directions aiming to improve the predictive power of the theory and its model.


Assuntos
Terrorismo , Violência , Humanos , Violência/psicologia , Terrorismo/psicologia , Agressão
13.
Trauma Violence Abuse ; 25(2): 1219-1234, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-37272372

RESUMO

In recent years, the concept of "misogynistic extremism" has emerged as a subject of interest among scholars, governments, law enforcement personnel, and the media. Yet a consistent understanding of how misogynistic extremism is defined and conceptualized has not yet emerged. Varying epistemological orientations may contribute to the current conceptual muddle of this topic, reflecting long-standing and on-going challenges with the conceptualization of its individual components. To address the potential impact of misogynistic extremism (i.e., violent attacks), a more precise understanding of what this phenomenon entails is needed. To summarize the existing knowledge base on the nature of misogynistic extremism, this scoping review analyzed publications within English-language peer-reviewed and gray literature sources. Seven electronic databases and citation indexes were systematically searched using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews (PRISMA-ScR) checklist and charted using the 2020 PRISMA flow diagram. Inclusion criteria included English peer-reviewed articles and relevant gray literature publications, which contained the term "misogynistic extremism" and other closely related terms. No date restrictions were imposed. The search strategy initially yielded 475 publications. After exclusion of ineligible articles, 40 publications remained for synthesis. We found that misogynistic extremism is most frequently conceptualized in the context of misogynistic incels, male supremacism, far-right extremism, terrorism, and the black pill ideology. Policy recommendations include increased education among law enforcement and Countering and Preventing Violent Extremism experts on male supremacist violence and encouraging legal and educational mechanisms to bolster gender equality. Violence stemming from misogynistic worldviews must be addressed by directly acknowledging and challenging socially embedded systems of oppression such as white supremacy and cisheteropatriarchy.


Assuntos
Terrorismo , Violência , Masculino , Humanos , Violência/prevenção & controle , Terrorismo/prevenção & controle , Agressão
14.
J Am Vet Med Assoc ; 262(2): 1-8, 2024 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-37948846

RESUMO

OBJECTIVE: A longitudinal study followed search-and-rescue (SAR) dogs for 15 years to determine the incidence of health events and whether factors of deployment during 9/11, breed, or sex altered the risk of specific events. ANIMALS: 150 SAR dogs: 95 dogs deployed to the September 11 terrorist attack sites and 55 SAR dogs not deployed. METHODS: Each year, a survey was sent to the handler to collect health information until the dog died or the handler withdrew from the study. The reported health events were then categorized according to the body system affected and etiology. Incidence risk rates, with 95% CIs, were calculated for the most common types of health events. Incidence rate ratios were calculated stratified by deployment status, sex, and breed and significance assessed. RESULTS: 1 or more health event was recorded in 96 of the 150 enrolled dogs. The most affected systems were the musculoskeletal (31%; CI, 24 to 39), integumentary (22%; CI, 15 to 29), and gastrointestinal (20%; CI, 14 to 26). The health events were most commonly reported as inflammatory (45%; CI, 37 to 53) and degenerative (28%; CI, 21 to 35) in nature. There were no significant differences in incidence of health events based on deployment status to the September 11, 2001, terrorist attacks. Additionally, there was no significant effect of breed or sex on incidence of health events. CLINICAL RELEVANCE: To improve the health and longevity of SAR dogs, disease prevention and management programs should focus on reducing the health problems involving the musculoskeletal system as well as the integumentary and gastrointestinal systems.


Assuntos
Doenças do Cão , Terrorismo , Cães , Animais , Estudos Longitudinais , Cães Trabalhadores , Trabalho de Resgate , Doenças do Cão/epidemiologia
16.
Forensic Sci Int ; 354: 111887, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38007870

RESUMO

Two commercially available portable Rapid DNA instruments were evaluated for their ability to process 1 µL and 10 µL saliva samples deposited on metal and plastic surfaces and contaminated with surrogates of cesium (Cs)-137, strontium (Sr)-90 and cobalt (Co)-60; radioactive materials potentially released during a nuclear weapon accident or a radiological dispersal device detonation. A comparable success rate was noted for both Rapid DNA instruments when considering the number of complete and balanced DNA profiles, the number of profiles with a minimum of 10 autosomal STR loci (out of 23 [FlexPlex™ 27] or 21 [GlobalFiler™ Express]), and the possibility to search a national DNA database in Canada and the United States. Cobalt had an adverse impact on the quality of the megaplex short tandem repeat (STR) DNA profiles derived on each instrument for two of the three contamination levels tested in this study, i.e., 0.05 M and 0.1 M as reflected by a reduced number of detected alleles and decreased profile peak heights. Strontium exhibited some adverse effect on the Rapid DNA results when used at the highest contamination level (0.1 M) whereas cesium had none. No new artifacts were observed in the Rapid DNA profiles of samples spiked with the non-radiogenic surrogates. Importantly, in the context of a radiological/nuclear (RN) event, the ANDE™ 6C offers the possibility to dispose of all radioactive materials associated with contaminated samples quickly using a chip on which all steps of the Rapid DNA process are performed whereas the RapidHIT™ ID accumulates radioactive materials for many days before disposal. An individual handling 25 samples in a week (5 per day) on the RapidHIT™ ID at a 30.5 cm distance with a 5 min exposure to the radioactive source estimated at every run would exceed the 0.042 µSv/5 min limit with gamma dose rates for Cs at 0.13 mSv and for Co at 3.8 mSv. Beta dose rates calculated for the surrogate isotopes at the three concentrations tested were also above the recommended radiation exposure limit of 1 mSv/yr (0.042 µSv/5 min). Various potential mechanisms of action behind the interference noted for Sr and Co at high concentrations are presented. These elements may play a role in the steps prior to PCR (at the DNA molecule by binding to bases or to phosphate groups), during PCR (at the DNA polymerase as cofactors for catalytic sites), or even during amplified DNA fragment detection (as fluorescence quenchers).


Assuntos
Impressões Digitais de DNA , Terrorismo , Impressões Digitais de DNA/métodos , Reação em Cadeia da Polimerase , Repetições de Microssatélites , Mucosa Bucal/química , DNA/análise , Radioisótopos de Cobalto/análise , Radioisótopos de Césio/análise , Radioisótopos de Estrôncio/análise
17.
J Forensic Sci ; 69(1): 241-251, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37919826

RESUMO

The subclassification of homicide-suicide into psychopathology and intrafamilial homicide-suicides having been presented in the foregoing Parts I and II, this Part III concerns extrafamilial homicide-suicides. Extrafamilial homicide-suicides are divided into adversarial, autogenic mass, cult, and terrorist homicide-suicides. Adversarial homicide-suicides involve a "formal" relationship between actor and homicide victims, further divided according to the role of the actor in their relationship as employee, current or former pupil/student as in school shootings, patient, and litigant. For comparison, school shootings were divided into those resulting in 10 or more homicide victims and those with fewer. The autogenic mass homicide-suicide, wherein victims are strangers to the actor, was heuristically bifurcated here depending on the number of homicide victims, 10 or more or fewer. As expected, the homicide-suicides with larger numbers of victims were more homogenous.


Assuntos
Suicídio , Terrorismo , Humanos , Homicídio , Estudantes
18.
Int J Legal Med ; 138(1): 295-299, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-36609734

RESUMO

In times of peace and except for terrorist attacks, fatalities by explosions are rare. Fireworks have deadly potential, especially self-made or illegally acquired devices. The use of professional pyrotechnics by untrained persons poses a life-threatening hazard. We present a case of devastating blunt force and blast injuries to the head and chest of a young man. After ignition of a display shell (syn. a real shell or mortar shell) without the use of a launching pipe, the device hit the man's face, nearly simultaneously followed by the explosion of the burst charge. The autopsy revealed injuries to the face and forehead as well as extensive tissue structure damage and a massive contusion with a bloody edema of the lungs. Autopsy results are supplemented with CT imaging and 3D reconstruction of the fractured mid face, as well as histological and toxicological examinations. This case of a misused display shell demonstrates both its devastating destructive potential and the corresponding and rarely observed injury pattern.


Assuntos
Traumatismos por Explosões , Terrorismo , Ferimentos não Penetrantes , Humanos , Traumatismos por Explosões/etiologia , Traumatismos por Explosões/patologia , Diagnóstico por Imagem , Ferimentos não Penetrantes/etiologia , Pulmão/patologia , Explosões
20.
Health Econ ; 33(1): 21-40, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37717244

RESUMO

How does terrorism affect child mortality? We use geo-coded data on terrorism and spatially disaggregated data on child mortality to study the relationship between both variables for 52 African countries between 2000 and 2017 at the 0.5 × 0.5° grid level. Our estimates suggest that moderate increases in terrorism are linked to several thousand additional annual deaths of children under the age of five. A panel event-study points to economic effects that are larger and compound over time. Interrogating our data, we show that the direct impact of terrorism tends to be very small. Instead, we theorize that terrorism causes child mortality primarily by triggering adverse behavioral responses by parents, medical workers, and policymakers. We provide tentative evidence in support of this argument.


Assuntos
Mortalidade da Criança , Terrorismo , Criança , Humanos , Pais
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