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1.
Am J Epidemiol ; 91(1): 68-77, Jan. 1970.
Artigo em Inglês | MedCarib | ID: med-14449

RESUMO

An outbreak of acute respiratory disease occurred among infants and pre-school-age children in nothern Trinidad during the last quater of 1967. There were 556 admissions to Port-of-Spain General Hospital during this period. Half of the children admitted were under 2 years of age, and 84 percent were under 5. A broad spectrum of clinical illness was observed, ranging from upper respiratory tract infection to bronchiolitis and pnuemonia. Para-influenza viruses were isolated from 12.3 percent of hospitalised children and were the only respiratory pathogens recovered in significant numbers. Para-influenza type 1, very rarely isolated during previous years, was the predominant serotype. Of 161 household contacts on whom paired sera were available, 14.3 percent had serologic evidence of recent para-influenza infection. Although age-specific prevalence rates among household contacts were similiar, respiratory illness more frequently ensued in younger individuals. Previous studies by the Trinidad Regional Virus Laboratory had shown para-influenza to be a cause of sparadic respiratory infections in Trinidadian children and respiratory syncytial virus to be associated with rainy season outbreaks of variable magnitude. This large-scale rainy season epidemic associated with para-influenza virus represents an epidemiologic pattern not previously recognized in Trinidad (Summary)


Assuntos
Humanos , Recém-Nascido , Lactente , Pré-Escolar , Criança , Masculino , Feminino , /epidemiologia , Infecções Respiratórias/microbiologia , Fatores Etários , Bronquiolite Viral/epidemiologia , Surtos de Doenças , Infecções por Orthomyxoviridae/microbiologia , Infecções Respiratórias/epidemiologia , Pneumonia Viral/epidemiologia , Sorotipagem , Trinidad e Tobago
2.
Am J Epidemiol ; 88(2): 257-66, Sept. 1968.
Artigo em Inglês | MedCarib | ID: med-12440

RESUMO

During 1964-1966, 94 cases of acute respiratory infection in Trinidad were found to be associated with respiratory syncytial virus infection. The clinical picture ranged from mild upper respiratory tract infection to severe infection of the lower respiratry tract. Seventy-nine of the patients were less than three years of age; 70 were diagnosed clinically as having bronchiolitis or pneumonia. Outbreaks of respiratory syncytial virus infection occurred annually during the rainy season in the second half of each year. The pattern was similar to that of temperate climates where outbreakes have occurred annually in the late fall and early winter or late winter and early spring. Although respiratory syncytial virus is reported to be relatively unstable, 18 strains of the virus were recovered from pharyngeal swabs that had been stored frozen at -56 C for 6-9 months. No antigenic relationships between respiratory syncytial virus and other myxoviruses were demonstrated by complement fixation tests on paired sera from three clinical cases of respiratory syncytial virus infection. The studies demonstrate the importance of respiratory pathogen on a tropical island. (AU)


Assuntos
Humanos , Lactente , Pré-Escolar , Criança , Adolescente , Adulto , Masculino , Feminino , Infecções por Orthomyxoviridae/epidemiologia , Vírus Sinciciais Respiratórios/isolamento & purificação , Infecções Respiratórias/microbiologia , Testes de Fixação de Complemento , Faringe/microbiologia , Nariz/microbiologia , Infecções por Orthomyxoviridae/imunologia , Vírus Sinciciais Respiratórios/imunologia , Infecções Respiratórias/epidemiologia , Trinidad e Tobago
3.
Am J Epidemiol ; 86(3): 690-9, Nov. 1967.
Artigo em Inglês | MedCarib | ID: med-13072

RESUMO

A survey of respiratory viruses and their antibodies in the Caribbean island of Jamaica has revealed that infleunza A, B and C viruses, parainfleunza type 1 and 3 viruses, respiratory syncytial virus and several types of adenovirus are causing respiratory infections in the Jamaican population. Respiratory virus infections were detected in Jamaica more frequently in the cooler months of the year, October through March, than in the warmer months. Adenoviruses were observed to be causing infections at all times of the year, but some evidence that parainfleunza type 1 infections are occurring at intervals only was obtained. Almost all infections by respiratory syncytial virus were obtained in infants and young children with severe lower respiratory tract disease.(Summary)


Assuntos
Humanos , Pré-Escolar , Criança , Adolescente , Masculino , Feminino , Infecções por Adenoviridae/epidemiologia , Infecções por Enterovirus/epidemiologia , Infecções por Herpesviridae/epidemiologia , Influenza Humana/epidemiologia , Infecções por Orthomyxoviridae/epidemiologia , Infecções Respiratórias/etiologia , Fatores Etários , Testes de Fixação de Complemento , Testes de Inibição da Hemaglutinação , Jamaica , Testes de Neutralização , /epidemiologia , Estações do Ano , Cultura de Vírus
4.
Am J Epidemiol ; 85(1): 101-7, Jan. 1967.
Artigo em Inglês | MedCarib | ID: med-13009

RESUMO

Mumps hemagglutination-inhibiting antibodies were clearly related to mumps history in diverse normal populations. A decline in titer of about twofold per decade after infection was observed in prospective and retrospective studies. This decline was such that many persons who had had mumps more than 15 years prior to testing had titers that could not be distinguished from non-immune. There was very little variation in titer over one month. Antibodies against four parainfluenza strains were tested for correlation with the discrepancies that were found between mumps serology and history. No correlation was found to suggest that parainfluenza causes a persistent aberration of mumps titer, but transient aberrations may occur.(Summary)


Assuntos
Humanos , Recém-Nascido , Lactente , Pré-Escolar , Criança , Adolescente , Adulto , Pessoa de Meia-Idade , Anticorpos/análise , Caxumba/imunologia , Infecções por Orthomyxoviridae/imunologia , África Ocidental , Alaska , Bahamas , Brasil , Canadá , Connecticut , Testes de Inibição da Hemaglutinação , Islândia , /imunologia , Vigilância da População , Ilhas do Pacífico
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