RESUMO
Granulosa-theca cell tumours are ovarian neoplasms of low malignancy with hormone secreting potential, accounting for 2-3 percent of all ovarian cancers. They have an uncertain clinical course and a potential for late recurrence aftet surgical removal. Clincal features of a patient presenting with pulmonary metastases 21 years after removal of the primary tumour are described, along with a review of the management options.(AU)
Assuntos
Relatos de Casos , Feminino , Humanos , Pessoa de Meia-Idade , Tumor de Células da Granulosa/secundário , Neoplasias Pulmonares/secundário , Neoplasias Ovarianas/patologia , Bignoniaceae/secundário , Seguimentos , Tumor de Células da Granulosa/patologia , Tumor de Células da Granulosa/cirurgia , Neoplasias Pulmonares/patologia , Neoplasias Pulmonares/cirurgia , Neoplasias Ovarianas/cirurgia , Ovariectomia , Pneumonectomia , Bignoniaceae/patologia , Bignoniaceae/cirurgiaRESUMO
The clinical and pathological features of 17 cases of feminizing mesenchymal tumours of the ovary observed over a 14-year period have been reviewed. (1) This group of neoplasms accounts for 3.4 percent of all primary ovarian tumours. (2) One case was observed before puberty and the others equally divided between women in the reproductive and the post-menopausal age groups. Most of the thecomas were observed in the reproductive period. (3) The tumours occurred in nulliparous patients and in those of low parity. (4) Vaginal bleeding and swelling of the abdomen were the most frequent presenting symptoms. The former symptom was, however, notably absent in the cases with pure granulosa cell growths. (5) All cases were treated surgically, the extent of the operation depending on the age of the patient and the presence of association uterine pathology. (6) The very large tumours were almost entirely cystic and all these cases died within 5 years. The thecomas were all benign. (7) Follow-up of these patients for life is essential as late recurrences of the tumours are a prominent feature (AU)
