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1.
West Indian med. j ; 33(2): 80-3, Sept. 1988.
Artigo em Inglês | MedCarib | ID: med-11489

RESUMO

Two hundred and seventy-eight deliveries were studied prospectively to determine the association between the use of oxytocin during labour and the incidence of neonatal jaundice. Jaundice was seen significantly more often in neonates following maternal infusion of oxytocin in dextrose water (OT) or dextrose water alone (DW) as compared to those whose mothers did not receive either. No significant difference was seen in the incidence of jaundice between OT or DW groups. Mean umbilical cord serum sodium levels were significantly lower in the OT and DW group neonates who became jaundiced, as compared to the rest of the neonates in the same group and the control group. Sixty per cent of the jaundiced neonates in the OT as well as the DW group had frank hyponatremia as compared to only 8 percent in the control group. These findings support a probable causative association between hyponatremia at birth and neonatal jaundice in the deliveries following dextrose water and/or oxytocin infusion (AU)


Assuntos
Feminino , Humanos , Recém-Nascido , Glucose/efeitos adversos , Icterícia Neonatal/induzido quimicamente , Trabalho de Parto , Trabalho de Parto Induzido , Ocitocina/efeitos adversos , Sangue Fetal/análise , Hiponatremia/induzido quimicamente , Hiponatremia/etiologia , Icterícia Neonatal/complicações , Gravidez , Estudos Prospectivos , Jamaica
2.
Br J Obstet Gynaecol ; 91(10): 1014-8, Oct. 1984.
Artigo em Inglês | MedCarib | ID: med-9578

RESUMO

Cord serum sodium levels in three groups of 278 singleton infants, born vaginally at term, were correlated with the incidence of jaundice (serum bilirubin o85æmol/1) in the first 3 days of life. Of the 278 infants, 87 were born to mothers who were given infusions of 5 percent or 10 percent glucose in water during labour (group I), 90 were born to mothers who received glucose solution as a vehicle for oxytocin (group II), and 101 to mothers who did not receive any intravenous fluid therapy (control group). Jaundice was seen significantly more frequently in groups I (28/87, 32 percent) and II infants (30/90, 33 percent) than in the control group (12/101, 12 percent) (P<0.01), but when analysed in relation to cord serum sodium levels, the prevalence of jaundice in the normonatraemic infants (serum sodium o131 mmol/1) was similar in the three groups. On the other hand, in groups I and II jaundice occurred about 3.5 times more frequently in the hyponatraemic infants (group I (17/32, 53 percent) and II (20/39, 51 percent) than in the normonatraemic infants (P<0.01). The difference was not associated with any other perinatal or neonatal characteristic.(AU)


Assuntos
Humanos , Gravidez , Recém-Nascido , Adulto , Feminino , Hidratação/efeitos adversos , Glucose/efeitos adversos , Hiponatremia/complicações , Icterícia Neonatal/etiologia , Sangue Fetal/análise , Hiponatremia/etiologia , Ocitocina/administração & dosagem , Estudos Prospectivos , Risco , Sódio/sangue
3.
West Indian med. j ; 33(Suppl): 47, 1984.
Artigo em Inglês | MedCarib | ID: med-6050

RESUMO

Umbilical cord serum sodium level in three groups of 278 term, vaginally delivered, singleton infants, were correlated with the incidence of jaundice (serum bilirubin 85 æmols/1) in the first 3 days of life. Eighty-seven infants were born to mothers who were given infusions of 5 percent or 10 percent glucose in water during labour (Group I); ninety were born to mothers who received glucose solution as a vehicle for oxytocin (Group II); and 101 whose mothers did not receive any intravenous fluid therapy served as controls. Jaundice was seen significantly more frequently in groups I (28/87, 31.5 percent) and II (30/90, 33 percent) infants compared with controls (12/101, 12 percent) (p<0.001); but when analysed in relation to umbilical cord serum sodium levels, the incidence of jaundice in normonatraemic infants (serum sodium < 131 mols/l) in the three groups was not different (p>0.1). On the other hand, the incidence of jaundice was about 3.5 times more in the hyponatraemic groups I (17/32, 53 percent) and II (20/39, 51 percent) infants as compared to normonatraemic infants in the same groups (p<0.01). The difference was not attributable to any other perinatal or neonatal characteristic. These findings lend support to our previous suggestion that there is a causative association between transplacental hyponatraemia and neonatal jaundice, and define one more category of infants 'at risk' for jaundice (AU)


Assuntos
Humanos , Recém-Nascido , Hiponatremia , Icterícia Neonatal , Solução Hipertônica de Glucose
5.
West Indian med. j ; 25(2): 67-72, June 1976.
Artigo em Inglês | MedCarib | ID: med-11178

RESUMO

A case is described of tuberculous endometritis associated with hyponatraemia probably resulting from inappropriate secretion of anti-diuretic hormone. An extensive search of the literature has failed to reveal another documented case of this association (AU)


Assuntos
Adulto , Feminino , Humanos , Endometrite/complicações , Hiponatremia/complicações , Tuberculose dos Genitais Femininos/complicações , Nigéria
6.
Am J Med Sci ; 263(3): 137-41, Mar. 1972.
Artigo em Inglês | MedCarib | ID: med-7190

RESUMO

A patient with diabetes mellitus treated with the sulfonylurea chlorpropamide developed the syndrome of inappropriate secretion of antidiuretic hormone. The mode of clinical presentation was one suggesting a central nervous system disorder. A clinical study of the patient's response to chlorpropamide was carried out. Headache, systolic hypertension, serum hypo-osmality, hyponatremia, urine hyperosmolality, fall in urinary output and continued renal excretion of sodium were demonstrated, confirming the initial diagnosis (AU)


Assuntos
Humanos , Feminino , Clorpropamida/efeitos adversos , Hiponatremia/induzido quimicamente , Vasopressinas/metabolismo , Doenças do Sistema Nervoso Central/induzido quimicamente , Clorpropamida/uso terapêutico , Diabetes Mellitus/tratamento farmacológico , Natriurese , Transtornos Urinários/induzido quimicamente , Concentração Osmolar , Síndrome , Fatores de Tempo
7.
West Indian med. j ; 17(4): 193-203, Dec. 1968.
Artigo em Inglês | MedCarib | ID: med-10748

RESUMO

The case is presented of a 69-year-old woman with a long standing lesion at the base of the brain who terminally developed the classical findings of the inappropriate secretion of antidiuretic hormone. It is postulated that the lesion, in close proximity to the pituitary stalk, could have acted as an irritative focus, resulting in over-production of antidiuretic hormone (AU)


Assuntos
Idoso , Feminino , Humanos , Aneurisma Intracraniano/complicações , Hiponatremia/etiologia , Hipopotassemia/etiologia
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