RESUMO
Thyrotoxic periodic paralysis is a rare endocrine disorder most prevalent among individuals of Asian descent that presents as proximal muscle weakness, hypokalemia, and signs of hyperthyroidism. We present the case report of a patient with previously undiagnosed hyperthyroidism, protracted muscle weakness with transient exacerbations, and nocturnal onset of periodic paralysis affecting the upper and lower limbs (AU)
Assuntos
Adulto , Relatos de Casos , Humanos , Masculino , Paralisias Periódicas Familiares/complicações , Tireotoxicose/complicações , Jamaica , Paralisias Periódicas Familiares/etnologia , Paralisias Periódicas Familiares/fisiopatologia , Paralisias Periódicas Familiares/terapia , Tireotoxicose/fisiopatologia , Tireotoxicose/terapiaRESUMO
A post menopausal female with severe vomiting and weight loss in association with elevated hormone levels is presented. Signs and symptoms of thyrotoxicosis were not evident at presentation. Possible pathophysiological mechanisms and treatment are discussed. Antithyroid therapy with carbimazole and propranlol induced rapid resolution of her symptoms and marked improvement in well-being. Radioactive iodine ablation of her thyroid gland was performed later and she has remained asymptomatic.(AU)
Assuntos
Feminino , Humanos , Pessoa de Meia-Idade , Relatos de Casos , Tireotoxicose/complicações , Vômito/etiologia , Tireotoxicose/terapia , Radioisótopos do Iodo/uso terapêutico , Redução de PesoRESUMO
A case of thyrotoxic periodic paralysis occurring in a Black Jamaican male patient is described. Diagnosis is based on history and confirmed by evaluation of serum electrolyte during attacks and thyroid function studies. The physiopathology, associations, therapy and prognosis are discussed. It is important that clinicians recognise the condition as all forms of periodic paralysis are amenable to treatment, and progressive weakness can be prevented or even reversed. (AU)
Assuntos
Humanos , Adulto , Masculino , Tireotoxicose/diagnóstico , Paralisias Periódicas Familiares/diagnóstico , Paralisias Periódicas Familiares/fisiopatologia , Paralisias Periódicas Familiares/terapia , Prognóstico , Jamaica , Testes de Função Tireóidea , Prognóstico , Tireotoxicose/fisiopatologiaAssuntos
Humanos , Masculino , Feminino , Adulto , Criança , Tireotoxicose/radioterapia , Barbados , Iodo/uso terapêuticoRESUMO
A case of mongolism, thyrotoxicosis and diabetes mellitus is reported. The literature on the status of the thyroid in mongolism is reviewed. Attention is drawn to the association of mongolism, thyrotoxicosis and diabetes mellitus, and a possible explanation for their association is discussed (AU)
Assuntos
Síndrome de Down , Tireotoxicose , Diabetes MellitusRESUMO
Thyroid acropachy is one of the more odd manifestaions of an endocrine disorder and is the last and rarest part of a syndrome comprising hyperthyroidism, exophthalmos and pretibial myxeodema, usually arising in that order. It is estimated that it occurs in 1 percent of patients with graves' disease and Melkinson (1963) could find only 26 authentic cases in the literature. Two cases of hyperthroidism and localized myxoedema are presented. In case I the mild degree of localized myxoedema disappeared with medical treatment of the hyperthyroidism. In case II thyroid acropachy. The McKenzie mouse bioassay for the long-acting thyroid stimulator (LATS) performed 3 years post thyroidectomy showed a moderately high LATS. This is in keeping with the observation that patients who develop pretibial myxoedema frequently have very high LATS levels. In contrast there is disagreement about the possible association between LATS and the eye signs of thyrotoxicosis (AU)
Assuntos
Humanos , Estimulador Tireóideo de Ação Prolongada/administração & dosagem , Doenças do Sistema Endócrino/tratamento farmacológico , Doenças do Sistema Endócrino/imunologia , TireotoxicoseRESUMO
The aneasthetic problems associated with thyroid surgery have been described. The importance of the history and of viewing the pre-operative x-rays of the patient's neck and thoracic inlet have been stressed, as well as adequate preparation of the toxic patient. The problems which may arise during surgery and their management have been discussed. Post-operative respiratory difficulties and their treatment are described (AU)
