Assuntos
Cricetinae , Camundongos , 21003 , Aminas/sangue , Reações Antígeno-Anticorpo , Fibroblastos/imunologia , Soros Imunes , Células L/imunologia , Lisossomos/imunologia , Técnicas de Cultura , Absorção , Contagem de Células , Linhagem Celular , Sobrevivência Celular , Proteínas do Sistema Complemento , Reações Cruzadas , Meios de Cultura , Histocitoquímica , Rim , Microscopia Eletrônica , Polímeros , Espermina , Fatores de TempoRESUMO
Beta-aminopropionaldehyde is one of the serum aldehydes whose level increases on treating serum with As2O3 and methanol. In animal tissues, beta-aminopropionaldehyde can arise directly from the oxidation of spermidine or diaminopropane. A pathway linking spermidine, b-aminopropionaldehyde and malondialdehyde to the control of RNA and DNA synthesis is proposed (AU)
Assuntos
Humanos , 21003 , Aldeídos/sangue , Metanol/farmacologia , Aldeídos/metabolismo , Oxirredutases atuantes sobre Doadores de Grupo CH-NH/metabolismo , Aminas/sangue , Arsenicais/farmacologia , Derivados de Benzeno , Divisão Celular/efeitos dos fármacos , Química , Cromatografia em Camada Delgada , Dinitrofenóis , DNA/biossíntese , Hidrazinas , Rim/enzimologia , Malonatos/análise , Propionatos/sangue , RNA/biossíntese , Espermina/metabolismo , SuínosRESUMO
Adrenaline and Noradrenaline both caused a contraction of the vas deferens. However, adrenaline was a more potent stimulant than noradrenaline. Isoprenaline by itself had no effect on the vas deferens, but it modified the stimulatory effect of subsequent administered adrenaline and noradrenaline. In small doses isoprenaline lessened and in large doses it potentiated the stimulating effect of the other two amines, the degree of inhibition by isoprenaline being greater on noradrenaline than on adrenaline. It was suggested that isoprenaline acted by inhibiting alpha adrenergic receptors in small concentrations, stimulating them in large concentrations and not by stimulating Beta receptors as is presently believed (AU)
