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1.
West Indian med. j ; 50(3): 230-3, Sept. 2001. ilus
Artigo em Inglês | MedCarib | ID: med-278

RESUMO

This paper reports two cases of benign hepatic cysts successfully treated by the instillation of tetracycline hydrochloride. The patients presented with solitary large symptomic hepatic cysts and underwent ultrasound guided needle aspiration followed by the instillation of tetracycline hydrochloride. The cyst size diminished without complication and the patients have remained symptom free. We review the treatment of this uncommon entity and propose that injection of tetracycline hydrochloride is an effective non-operative treatment of symptomatic solitary hepatic cysts. (AU)


Assuntos
Idoso , Humanos , Masculino , Relatos de Casos , Adolescente , Tetraciclinas/uso terapêutico , Cistos/terapia , Escleroterapia , Hepatopatias/terapia , /uso terapêutico , Drenagem , Idoso de 80 Anos ou mais , /administração & dosagem , Cistos/diagnóstico por imagem , Instilação de Medicamentos , Hepatopatias/diagnóstico por imagem , Tetraciclina/administração & dosagem
2.
Artigo em Inglês | MedCarib | ID: med-17769

RESUMO

Antimicrobial susceptibility patterns of strains of Escherichia coli isolated between 1994 and 1998 were studied. Of the 1,283 strains examined, 75% were recovered from urine, 8.7% from wounds, 3.2% from blood, 2.6% from pus, and 10.5% from other sources. Isolates from inpatients and outpatients accounted for 46.1% and 53.9%, respectively. Gentamicin and nalidixic acid showed the greatest efficacy against isolates from both inpatients and outpatients, revealing a >90% sensitivity. Drugs with the lowest efficacies were ampicillin and amoxicillin-clavulanic acid, which showed a >45% resistance. Tetracycline showed a significant decline in resistance from 1994 to 1998 among strains from both inpatients and outpatients (P < 0.001). This decline may be related to a policy of restrictive antibiotic reporting by the Microbiology Laboratory and seminars for general practitioners, subsequent to an island-wide survey an antibiotic resistance. A similar pattern of declining resistance was also observed for cefuroxime. E. coli sensitivity to co-trimoxazole was relatively stable during the study period. Although the overall prevalence of resistance among E. coli strains is relatively low, on-going surveillance of bacterial resistance must continue. The microbial antibiogram can provide general practitioners and clinicians with data essential for optimum empiric choices. Further, the introduction of a policy of restrictive reporting may act "synergistically" with the education of doctors on resistance patterns, to effect island-wide reduction of antimicrobial resistance.


Assuntos
Humanos , Estudo Comparativo , Combinação Amoxicilina e Clavulanato de Potássio/farmacologia , Ampicilina/farmacologia , Antibacterianos/farmacologia , Escherichia coli/efeitos dos fármacos , Infecções por Escherichia coli/tratamento farmacológico , Infecções por Escherichia coli/microbiologia , Cefuroxima/farmacologia , Cefalosporinas/farmacologia , Resistência Microbiana a Medicamentos , Gentamicinas/farmacologia , Hospitais Privados , Testes de Sensibilidade Microbiana , Ácido Nalidíxico/farmacologia , Penicilinas/farmacologia , Tetraciclina/farmacologia , Trinidad e Tobago
3.
J Wildl Dis ; 30(4): 497-505, Oct. 1994.
Artigo em Inglês | MedCarib | ID: med-4736

RESUMO

A field of study was conducted on Antigua, West Indies to determine the feasibility of delivering an oral rabies vaccine or population control agent to free-ranging mongooses (Herpestes javanicua). Two biomarkers (tetracycline hydrochloride [THCL] and Dupoint Oil Blue A dye) and two bait types (Dupont polymer fish meal and polyurethane foam) were used to bait three study sites. Four hundred polymer baits containing both biomarkers were distributed at 36 central point bait stations (11 baits/station) on an 80 ha study site (5 baits/ha); 69 percent of the mongoose population consumed one or more baits. Two thousand baits containing THCL and 400 baits containing DuPont dye were distributed on two additional 100 ha study sites (24 baits/ha). Polymer fish meal baits were used on the first site and polyurethane baits on the second site. Based on the presence of biomarkers in bone or soft tissue, 96 to 97 percent of the mongooses at both sites consumed at least one bait. We conclude that oral baiting of mongooses is a feasible method for delivery of vaccines for the control of rabies in this species (AU)


Assuntos
Feminino , Masculino , 21003 , Vacina Antirrábica/administração & dosagem , Vacinação/veterinária , Herpestidae , Tecido Adiposo/química , Administração Oral , Antraquinonas/administração & dosagem , Antraquinonas/análise , Biomarcadores , Medula Óssea/química , Corantes/administração & dosagem , Corantes/análise , Mandíbula , Polímeros , Poliuretanos , Cauda , Tetraciclina/administração & dosagem , Tetraciclina/análise
4.
West Indian med. j ; 41(Suppl 1): 55, April 1992.
Artigo em Inglês | MedCarib | ID: med-6544

RESUMO

During the period, January 1989 to December 1990, 41 women or 25 percent of all female patients between the ages of 15 and 50 years who presented to a private family practice were diagnosed as having pelvic inflammatory disease (PID). Seventy-eight per cent were between the ages of 20 and 40 years, 83 percent presented with pain, 56 percent with vaginal discharge and 15 were infertile. Fifty-one percent were treated with a combination of tetracyline and metronidazole and 22 percent with cotrimoxazole. Seventy-four per cent obtained a symptomatic cure and 26 percent continued with persistent pain. Forty-five per cent of 11 patients presenting with rupture tubal pregnancy gave a history of previous PID. A review of the results of bacteriological investigation of women with PID over the period January 1989 to December 1990 showed that 49.7 percent had no pathogens, 26.4 percent had candida albicans, 8.2 percent trichomonas, 46 percent E. Coli, 4.6 percent haemophilus, 4.4 percent streptococcus, 15 percent N. Gonorrhea and 10.4 percent other organisms (AU)


Assuntos
Humanos , Adolescente , Adulto , Feminino , Doença Inflamatória Pélvica/epidemiologia , Índias Ocidentais , Infertilidade Feminina , Tetraciclina/uso terapêutico , Metronidazol/uso terapêutico , Candida albicans , Trichomonas , Haemophilus
5.
West Indian med. j ; 40(Suppl. 2): 100, July 1991.
Artigo em Inglês | MedCarib | ID: med-5216

RESUMO

The efficacy of roxythromycin 150 mg twice daily was evaluated for treatment of NGU caused by Chlamydia trachomatis in an adult outpatient setting with a high non-compliance level. Eligible patients were male adults (> 18 years) attending a sexually transmitted diseases (STD) clinic in Kingston with uncomplicated NGU. Chlamydial aetiology was identified by direct immunofluorescence and tissue culture techniques using monoclonal antibodies for final confirmation. In a 14-week study, 245 cases of NGU were identified of which 178 (72.7 per cent) were Chlamydia-positive. The results showed that C. trachomatis was eradicated from 87.2 per cent of the 125 patients finally evaluable. The prevalence of C. trachomatis is high in genital infections in Jamaica. These results indicated that roxythromycin was a suitable alternative for treatment in view of reports of resistance to tetracycline. A distinct advantage of roxythromycin was the twice daily dosage compared with four times daily for tetracycline, in treating a common sexually transmitted disease in a population group with a high non-compliance rate (AU)


Assuntos
Humanos , Masculino , Infecções por Chlamydia/tratamento farmacológico , Uretrite/tratamento farmacológico , Roxitromicina/uso terapêutico , Tetraciclina/administração & dosagem , Jamaica
7.
West Indian med. j ; 39(2): 124-7, June 1990.
Artigo em Inglês | MedCarib | ID: med-14171

RESUMO

Medication-induced oesophagitis is an unusual cause of aesophageal damage. A patient is presented who developed sudden onset of odynophagia and dysphagia while taking tetracycline. Endoscopy revealed proximal oesophagitis which was confirmed histologically. Symptoms resolved rapidly after stopping the offending drug. Drug-induced oesophagitis should be considered in patients with unexplained oesophageal symptoms. This condition is often unrecognized as symptoms usually resolve on cessation of the drug. Prevention is the best approach (AU)


Assuntos
Humanos , Adulto , Feminino , Esofagite/induzido quimicamente , Tetraciclina/efeitos adversos
8.
West Indian med. j ; 30(2): 63-7, June 1981.
Artigo em Inglês | MedCarib | ID: med-11346

RESUMO

The antibiotic sensitivity of 113 strains of N. gonorrhoeae collected in Kingston and Montego Bay in 1978 was compared to that of 26 strains collected in Kingston in 1971. In 1971, 38 percent of the gonococcal isolates in Jamaica grew in the presence of >0.25 æg/ml of penicillin (0.4 units) compared to only 8.9 percent in 1978. A similar decrease in the level of tetracycline resistance (MIC>1.0 æg/ml) was also seen from 1971, when 31 percent of gonococcal isolates were resistant, to 1977 when only 13.4 percent were resistant. The percentage of antibiotic resistance of strains of N. gonorrhoeae in Jamaica was higher than were contemporary isolates from the United States in both 1971 and 1978. The level of penicillin and tetracycline resistance of the 1978 strains were less than those of the 1971 strains, but were higher as a group than contemporary gonococci isolated in the United States (AU)


Assuntos
Feminino , Humanos , Técnicas In Vitro , Masculino , Neisseria gonorrhoeae/efeitos dos fármacos , Penicilinas/farmacologia , Tetraciclina/farmacologia , Resistência Microbiana a Medicamentos , Testes de Sensibilidade Microbiana , Jamaica , Estados Unidos
9.
West Indian med. j;23(4): 226-31, Dec. 1974.
em Inglês | MedCarib | ID: med-11064

RESUMO

The sensitivity of penicillin and tetracycline of 53 strains of gonococci isolated in the Summer of 1971 from routine cases in a clinic in Kingston, Jamaica, has been determined. The level of sensitivity of Jamaican strains to these antibiotics was remarkably similar to the sensitivity to these antibiotics of routine strains isolated over the United States in 1970-71. There was a remarkable correlation of sensitivities to penicillin and tetracycline of individual strains. The similarity of sensitivity of strains in Jamaica to the sensitivity of strains in the United States and the good correlation of the degree of sensitivity of individual strains to the two drugs lend support to the hypothesis of Sparling (1972) and of Maness and Sparling (1973) of a common genetic pathway responsible for the development of most cases of resistance to these antibodies (AU)


Assuntos
Resistência Microbiana a Medicamentos , Neisseria gonorrhoeae/efeitos dos fármacos , Penicilinas/farmacocinética , Tetraciclina/farmacocinética , Testes de Sensibilidade Microbiana , Resistência às Penicilinas , Especificidade da Espécie , Jamaica
10.
J Hyg ; 71(1): 209-15, Mar. 1973.
Artigo em Inglês | MedCarib | ID: med-15804

RESUMO

The antibiotic resistance patterns of califorms in faecal specimens from pigs and their human contacts were studied. The ability of the resistant coliforms to transfer their resistance in vitro to antibiotic-sensitive recipients was examined. The results showed that pigs which had received antibiotics carried more multiply-resistant, R-factor bearing coliforms than pigs which had not been given antibiotics. Human contacts of the antibiotic-treated pigs had a higher incidence of antibiotic-resistant coliforms with R-factors than contacts of pigs which had not been given antibiotics. It is concluded that antibiotic treatment of farm animals may lead to acquisition of antibiotic resistance by gut coliforms of man.(AU)


Assuntos
Humanos , 21003 , Herança Extracromossômica , Resistência às Penicilinas , Doenças dos Suínos/microbiologia , Zoonoses , Ampicilina , Cloranfenicol , Reservatórios de Doenças , Fezes/microbiologia , Estreptomicina , Sulfonamidas , Suínos , Tetraciclina
11.
Stethoscope ; 7(1): 26-8, 1971.
Artigo em Inglês | MedCarib | ID: med-9127

RESUMO

Only methisazone and amantadine of the synthetic antiviral agents are commercially available for general use, and they are used only prophylactically. Interferon inducers are promising but as yet untested in man. No doubt effective chemotherapeutic agents will in time become available but for the present and immediate future, vaccines will provide the first line of defence against disease. Methods of immunization are bound to improve and with an increasing awareness of public health measures the role of antiviral chemotherapeutic agents though important, will be minor. (Summary)


Assuntos
Humanos , Viroses/tratamento farmacológico , Tiossemicarbazonas/uso terapêutico , Desoxirribonucleases/uso terapêutico , Amantadina/uso terapêutico , Interferons/uso terapêutico , Mycoplasma , Tetraciclina/uso terapêutico , Cloranfenicol/uso terapêutico , Sulfadiazina/uso terapêutico
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