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1.
Artigo em Inglês | MedCarib | ID: med-17792

RESUMO

The importance of laser photostimulation is now accepted generally but the laser light facilitates wound healing and tissue repair remains poorly understood. So we have examined the hypothesis that the laser photo stimulation can enhances the collagen production in excision wounds using excision wound model in Wister rat model. The circular wounds were created on the dorsum of the back of the animals. The animals were divided into two groups. The experimental group (n = 12) wound was treated with 632.8 nm He-Ne laser at a dose of 2.1J cmƒ{2 for five days a week until the complete healing. The control group was sham irradiated. The parameters studied were wound area, period of epithelization and hydroxyproline. Significant increase in the hydroxyproline content (p<0.001) and reduction in the wound size (p<0.001) was observed in study group when compared to controls. The significant epithelization (p<0.001) was noticed. The experimental wounds were, on average, fully healed by the 15th day, whereas the control group healed, on average by 22nd day. Wound contraction together with the hydroxyproline and experimental observations suggested that low intensity Helium-Neon laser photo stimulation facilitates the tissue repair process by accelerating collagen production in chronic wounds.


Assuntos
Ratos , Animais , Cicatrização , Hélio , Lasers , Ratos Wistar/lesões , Ratos Wistar/fisiologia , Trinidad e Tobago
2.
Eye ; 7(5): 703-6, 1993.
Artigo em Inglês | MedCarib | ID: med-8043

RESUMO

The effect of sectoral, scatter laser photocoagulation on proliferative sickle retinopathy (PSR) was investigated by reviewing florescein angiograms of 88 sickle cell-haemoglobin C patients enrolled in a controlled, randomised trial. Follow-up was for a median period of 2.9 years. Complete infarction of all PSR in an eye occurred in 7 of 74 treated eyes and 2 0f 60 control eyes. Treatment resulted in significantly greater regression (decrease in number and size of PSR lesions) in eyes of patients aged <25 years at enrollment but not in eyes of patients> or = 25 years at enrollment. Infarction of the individual PSR lesions was significantly more common in treated eyes. Treated PSR was significantly more likely to infarct if small (< 15 degrees circumferential involvement) and if flat rather than elevated. New PSR was significantly less likely to develop in treated eyes.


Assuntos
Humanos , Adulto , Doenças Retinianas/cirurgia , Doença da Hemoglobina C/complicações , Lasers , Retina/cirurgia , Angiofluoresceinografia , Doenças Retinianas/etiologia
3.
Ophthalmology ; 90(5): 540-5, May 1983.
Artigo em Inglês | MedCarib | ID: med-9334

RESUMO

A randomized prospective clinical trial of feeder vessel photocoagulation for proliferative sickle cell retinopathy was performed. In Chicago, there were 34 argon laser-treated eyes and 30 control eyes. In Kingston, there were 53 xenon arc treated eyes and 50 control eyes. Prolonged loss of visual acuity was rare in both photocoagulated and control eyes. Argon laser and xenon arc feeder vessel photocoagulation reduced the incidence of vitreous hemorrhage and visual loss from vitreous hemorrhage. However, photocoagulation was associated with an increased risk of choroidal neovascularization (xenon arc greater than argon laser) and retinal detachment (argon laser), although visual loss from these complications has not been in these patients so far. (AU)


Assuntos
Humanos , Adulto , Masculino , Feminino , Anemia Falciforme/complicações , Lasers/uso terapêutico , Doenças Retinianas/cirurgia , Lasers/métodos , Corioide/irrigação sanguínea , Ensaios Clínicos como Assunto , Estudo Comparativo , Seguimentos , Lasers/efeitos adversos , /etiologia , Distribuição Aleatória , Descolamento Retiniano/etiologia , Doenças Retinianas/etiologia
4.
Br J Ophthalmol ; 65(3): 192-7, Mar. 1981.
Artigo em Inglês | MedCarib | ID: med-9371

RESUMO

Choroidal neovascularisation occurred in 35 out of 57 (61 percent) patients during a trial of xenon arc photocoagulation in proliferative sickle retinopathy. Nineteen patients manifested abnormal vessel systems in the plane of the retina which tended to be benign, not enlarging and without complications (choroidoretinal neovascularization). In 16 patients the abnormal vessel system grew into the vitreous, tended to increase in size and to be associated with vitreous haemorrhage and retinal traction (choroidovitreal neovascularisation). Both forms of neovascularisation were significantly more common at younger ages. Treatment was generally unsatisfactory, frequently resulting in further enlargement of the lesions. Although the natural history of choroidal neovascularisation and its ultimate effect on visual function remains to be recorded, these lesions constitute a common and potentially serious complication of xenon arc photocoagulation in proliferative sickle retinopathy as currently performed. (Summary)


Assuntos
Humanos , Adolescente , Adulto , Pessoa de Meia-Idade , Masculino , Feminino , Anemia Falciforme/cirurgia , Corioide/irrigação sanguínea , Lasers/efeitos adversos , Lasers/uso terapêutico , Fatores Etários , Angiofluoresceinografia , Seguimentos , Fatores de Tempo , Doenças da Úvea/etiologia , Doenças da Úvea/patologia
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