RESUMO
This publication presents an up-to-date and in-depth review of the effects of Chargas' disease on the nervous system, highlighting the alterations seen in patients as well as the mechanisms by which the pathology is produced
Following an overview of the public health problems posed by Chagas' disease (also knows as American trypanosomiasis) and how they are being addressed, the book describes studies of specific alterations in autonomic, peripheral, and central nervous functios produced by chagasic infection in humans, including childre suffering from congenital infection. The next section presents the latest findings on the possible role fo the body's immune response in the genesis of nervous tissue lesions in Chagas' disease. The final two chapters discuss studies of nervous system pathology in two experimental models, mice and monkeys, and how they can enhance understanding of the infection in humans
Researchers in immunology, neurology, and parasitic diseases will find this book to be a compendium of state-of-the-art knowledge, and it will provide physicians and other health professionals who may encounter persons afficted with this widespread parasitosis with valuable insight into these patients' conditions
