Assuntos
COVID-19 , Vacinas contra COVID-19 , Betacoronavirus , Surtos de Doenças , Trombose , Trombocitopenia , Guia , Administração de Caso , Medicina ClínicaAssuntos
COVID-19 , Betacoronavirus , Surtos de Doenças , Vacinas contra COVID-19 , Trombose , Trombocitopenia , Guia , Administração de Caso , Medicina ClínicaAssuntos
COVID-19 , Betacoronavirus , Surtos de Doenças , Vacinas contra COVID-19 , Trombose , Trombocitopenia , Guia , Administração de Caso , Medicina ClínicaAssuntos
COVID-19 , Betacoronavirus , Surtos de Doenças , Trombose , Trombocitopenia , Guia , Administração de Caso , Medicina ClínicaAssuntos
COVID-19 , Betacoronavirus , Surtos de Doenças , Vacinas contra COVID-19 , Trombose , Trombocitopenia , Guia , Administração de Caso , Medicina ClínicaAssuntos
Embolia , Vasos Coronários , Próteses Valvulares Cardíacas , Trombose , Infarto do MiocárdioRESUMO
This study determined the prevalence of inherited factor V Leiden mutation in a group of 128 thrombosis patients [102 with venous thrombosis and 26 with arterial thrombosis] attending a hospital in Sousse, Tunisia, and a control group of 100 with no history of thrombosis. Using an allele-specific PCR amplification technique, factor V Leiden was found in significantly more patients [20.3%] than controls [6.0%]. The higher prevalence was significant in the subgroup of venous thrombosis patients but not in arterial thrombosis patients. The allele frequency was 3.5% in the normal Tunisian population. Screening Tunisian patients with venous thrombosis and their relatives for factor V Leiden may be justified
Assuntos
Mutação , Trombose , Prevalência , Reação em Cadeia da Polimerase , Fator VAssuntos
Resistência à Proteína C Ativada , Fator V , Infarto , Mutação , Placenta , Gravidez , Trombose , Aborto HabitualAssuntos
Cinerradiografia , Ecocardiografia Transesofagiana , Eletrocardiografia , Fibrinolíticos , Cardiopatias , Próteses Valvulares Cardíacas , Infusões Intravenosas , Gravidez , Complicações Cardiovasculares na Gravidez , Resultado da Gravidez , Primeiro Trimestre da Gravidez , Trombose , EstreptoquinaseRESUMO
A group of 40 thalassaemic patients [20 splenectomized and 20 nonsplenectomized] from the Haematology Unit of Tanta University Hospital [age range: 3-14 years] were studied to identify the mechanisms by which haemorrhagic and thrombotic complications occur in thalassaemic patients. The patients' levels of protein C, antithrombin III and in vitro platelet aggregation in response to collagen were compared with those of 20 controls. The study suggests that thrombocytosis, increased platelet aggregation and decreased natural coagulation inhibitors [protein C and antithrombin III] in splenectomized thalassaemic children may be significant in thrombotic complications in such patients. Defective platelet aggregation and prothrombin activity in nonsplenectomized children may also give rise to haemorrhagic tendencies