Sorbitol crystallization-induced aggregation in frozen mAb formulations.
Piedmonte, Deirdre Murphy; Hair, Alison; Baker, Priti; Brych, Lejla; Nagapudi, Karthik; Lin, Hong; Cao, Wenjin; Hershenson, Susan; Ratnaswamy, Gayathri.
J Pharm Sci
; 104(2): 686-97, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-25219372
Assessment of different systems for the production of aldonic acids and sorbitol by calcium alginate-immobilized Zymomonas mobilis cells.
Naturally occurring osmolytes modulate the nanomechanical properties of polycystic kidney disease domains.
Protective effect of sorbitol on enzymes exposed to microsecond pulsed electric field.
Distinctive solvation patterns make renal osmolytes diverse.
The binuclear form of dinitrosyl iron complexes with thiol-containing ligands in animal tissues.
Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.
Influence of sorbitol on protein crowding in solution and freeze-concentrated phases.
Osmolyte effects on the self-association of concanavalin A: testing theoretical models.
Metastability Gap in the Phase Diagram of Monoclonal IgG Antibody.
Intra-spike crosslinking overcomes antibody evasion by HIV-1.