Annotation of pseudogenic gene segments by massively parallel sequencing of rearranged lymphocyte receptor loci.
Dean, Jared; Emerson, Ryan O; Vignali, Marissa; Sherwood, Anna M; Rieder, Mark J; Carlson, Christopher S; Robins, Harlan S.
; 7: 123, 2015 Nov 23.
Artigo em Inglês | MEDLINE | ID: mdl-26596423
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Decision checkpoints in the thymus.
Chromatin conformation governs T-cell receptor Jß gene segment usage.
Disease etiology and diagnosis by TCR repertoire analysis goes viral.
Noncanonical mode of ERK action controls alternative αß and Î³Î´ T cell lineage fates.
A role for differential variable gene pairing in creating T cell receptors specific for unique major histocompatibility ligands.
An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells.
Robust control of the adaptive immune system.
Dynamics of Individual T Cell Repertoires: From Cord Blood to Centenarians.