CD26/DPPIV inhibition alters the expression of immune response-related genes in the thymi of NOD mice.
Julián, María Teresa; Alonso, Núria; Colobran, Roger; Sánchez, Alex; Miñarro, Antoni; Pujol-Autonell, Irma; Carrascal, Jorge; Rodríguez-Fernández, Silvia; Ampudia, Rosa María; Vives-Pi, Marta; Puig-Domingo, Manel.
Mol Cell Endocrinol
; 426: 101-12, 2016 May 05.
Artigo em Inglês | MEDLINE | ID: mdl-26911933
Transcriptional programs that control expression of the autoimmune regulator gene Aire.
Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth.
Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs.
Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy.
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The transcriptional regulator Aire binds to and activates super-enhancers.
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Chemical and mechanical stimuli act on common signal transduction and cytoskeletal networks.
Diverse reprogramming codes for neuronal identity.