Cold-Adapted Viral Attenuation (CAVA): Highly Temperature Sensitive Polioviruses as Novel Vaccine Strains for a Next Generation Inactivated Poliovirus Vaccine.
Sanders, Barbara P; de Los Rios Oakes, Isabel; van Hoek, Vladimir; Bockstal, Viki; Kamphuis, Tobias; Uil, Taco G; Song, Yutong; Cooper, Gillian; Crawt, Laura E; Martín, Javier; Zahn, Roland; Lewis, John; Wimmer, Eckard; Custers, Jerome H H V; Schuitemaker, Hanneke; Cello, Jeronimo; Edo-Matas, Diana.
; 12(3): e1005483, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-27032093
Experimental Evolution to Study Virus Emergence.
The Evolutionary Pathway to Virulence of an RNA Virus.
A RT-PCR method for selective amplification and phenotypic characterization of all three serotypes of Sabin-related polioviruses from viral mixtures.
La vacuna polio oral en lactantes no interfiere con la detección de enterovirus en sangre.
A safe and reliable neutralization assay based on pseudovirus to measure neutralizing antibody titer against poliovirus.
New Strains Intended for the Production of Inactivated Polio Vaccine at Low-Containment After Eradication.
Planning for globally coordinated cessation of bivalent oral poliovirus vaccine: risks of non-synchronous cessation and unauthorized oral poliovirus vaccine use.
Limits of variation, specific infectivity, and genome packaging of massively recoded poliovirus genomes.
Development of a multiplex RT-PCR assay for the identification of recombination types at different genomic regions of vaccine-derived polioviruses.
Continued use of poliovirus after eradication: hyper-attenuated strains as a safe alternative for release testing of human immunoglobulins.