1,5-Diazacyclooctanes, as Exclusive Oxidative Polyamine Metabolites, Inhibit Amyloid- (1-40) Fibrillization.
Tsutsui, Ayumi; Zako, Tamotsu; Bu, Tong; Yamaguchi, Yoshiki; Maeda, Mizuo; Tanaka, Katsunori.
Adv Sci (Weinh)
; 3(10): 1600082, 2016 10.
Artigo em Inglês | MEDLINE | ID: mdl-27840798
Unexplored Chemical Reactions of Endogenous Acrolein: Detection, Toxicity, and Biological Roles.
Imino [4+4] cycloaddition products as exclusive and biologically relevant acrolein-amine conjugates are intermediates of 3-formyl-3,4-dehydropiperidine (FDP), an acrolein biomarker.
Computational insight into the carbenic character of nitrilimines from a reactivity perspective.
Novel electrochemical approach to enhanced toxicity of 4-oxo-2-nonenal vs. 4-hydroxy-2-nonenal (role of imine): oxidative stress and therapeutic modalities.
Î³-Hydroxy-1,N2-propano-2'-deoxyguanosine DNA adduct conjugates the N-terminal amine of the KWKK peptide via a carbinolamine linkage.
Catalytic asymmetric umpolung reactions of imines.
Identification of a novel acetylated form of branched-chain polyamine from a hyperthermophilic archaeon Thermococcus kodakarensis.
Solid-phase synthesis and screening of N-acylated polyamine (NAPA) combinatorial libraries for protein binding.
Broad Spectrum Enolate Equivalent for Catalytic Chemo-, Diastereo-, and Enantioselective Addition to N-Boc Imines.
Secondary and primary amine catalysts for iminium catalysis.