Superoxide dismutase 1 is positively selected to minimize protein aggregation in great apes.
Dasmeh, Pouria; Kepp, Kasper P.
Cell Mol Life Sci
; 74(16): 3023-3037, 2017 08.
Artigo em Inglês | MEDLINE | ID: mdl-28389720
Alterations in local stability and dynamics of A4V SOD1 in the presence of trifluoroethanol.
SALS-linked WT-SOD1 adopts a highly similar helical conformation as FALS-causing L126Z-SOD1 in a membrane environment.
An in silico study of the effect of SOD1 electrostatic loop dynamics on amyloidlike filament formation.
CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1) ALS mice originate from astrocytes and neurons and carry misfolded SOD1.
Characterization of Cu/Zn-SOD enzyme activities and gene expression in soybean under low nitrogen stress.
Molecular mechanisms underlying the impact of mutations in SOD1 on its conformational properties associated with amyotrophic lateral sclerosis as revealed with molecular modelling.
Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS).
Chronic electromyograms in treadmill running SOD1 mice reveal early changes in muscle activation.
Tricking a Protein To Swap Strands.
SOD1 in Amyotrophic Lateral Sclerosis: "Ambivalent" Behavior Connected to the Disease.