Synthesis and evaluation of anthranilamide-based derivatives as FXa inhibitors.
Huang, Changjiang; Wang, Wenzhi; Li, Yao; Zhang, Shijun; Meng, Fancui; Xu, Weiren; Yuan, Jing; Chen, Ligong.
; 8(23): 37186-37199, 2017 Jun 06.
Artigo em Inglês | MEDLINE | ID: mdl-28415603
Novel Anthranilamide-Based FXa Inhibitors: Drug Design, Synthesis and Biological Evaluation.
Qualitative and quantitative pharmacophore-similarity assessment of anthranilamide-based factor Xa inhibitors: applications on similar molecules with identical biological endpoints.
Identification of anthranilamide derivatives as potential factor Xa inhibitors: drug design, synthesis and biological evaluation.
Anthranilamide-based N,N-dialkylbenzamidines as potent and orally bioavailable factor Xa inhibitors: P4 SAR.
Anthranilic acid derivatives as novel ligands for farnesoid X receptor (FXR).
Discovery and initial optimization of alkoxyanthranilic acid derivatives as inhibitors of HCV NS5B polymerase.
Identification of potent orally active factor Xa inhibitors based on conjugation strategy and application of predictable fragment recommender system.
Identification of novel plasminogen activator inhibitor-1 inhibitors with improved oral bioavailability: Structure optimization of N-acylanthranilic acid derivatives.
Synthesis and Caco-2 cell permeability of N-substituted anthranilamide esters as ADP inhibitor in platelets.
Distribution of the tryptophan pathway-derived defensive secondary metabolites gramine and benzoxazinones in Poaceae.