Identification of a Potent, Selective, and Efficacious Phosphatidylinositol 3-Kinase δ (PI3Kδ) Inhibitor for the Treatment of Immunological Disorders.

Liu, Qingjie; Shi, Qing; Marcoux, David; Batt, Douglas G; Cornelius, Lyndon; Qin, Lan-Ying; Ruan, Zheming; Neels, James; Beaudoin-Bertrand, Myra; Srivastava, Anurag S; Li, Ling; Cherney, Robert J; Gong, Hua; Watterson, Scott H; Weigelt, Carolyn; Gillooly, Kathleen M; McIntyre, Kim W; Xie, Jenny H; Obermeier, Mary T; Fura, Aberra; Sleczka, Bogdan; Stefanski, Kevin; Fancher, R M; Padmanabhan, Shweta; Rp, Thatipamula; Kundu, Ipsit; Rajareddy, Kallem; Smith, Rodney; Hennan, James K; Xing, Dezhi; Fan, Jingsong; Levesque, Paul C; Ruan, Qian; Pitt, Sidney; Zhang, Rosemary; Pedicord, Donna; Pan, Jie; Yarde, Melissa; Lu, Hao; Lippy, Jonathan; Goldstine, Christine; Skala, Stacey; Rampulla, Richard A; Mathur, Arvind; Gupta, Anuradha; Arunachalam, Pirama Nayagam; Sack, John S; Muckelbauer, Jodi K; Cvijic, Mary Ellen; Salter-Cid, Luisa M.
J Med Chem; 60(12): 5193-5208, 2017 Jun 22.
Artigo em Inglês | MEDLINE | ID: mdl-28541707