Therapeutic silence of pleiotrophin by targeted delivery of siRNA and its effect on the inhibition of tumor growth and metastasis.
Zha, Lisha; He, Lichun; Xie, Weidong; Cheng, Jin; Li, Tong; Mohsen, Mona O; Lei, Fan; Storni, Federico; Bachmann, Martin; Chen, Hongquan; Zhang, Yaou.
; 12(5): e0177964, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28562667
Intravenous delivery of siRNA targeting CD47 effectively inhibits melanoma tumor growth and lung metastasis.
Macrophage migration inhibitory factor produced by the tumour stroma but not by tumour cells regulates angiogenesis in the B16-F10 melanoma model.
Distinct roles for LINE-1 and HERV-K retroelements in cell proliferation, differentiation and tumor progression.
Systemic delivery of siRNA via LCP nanoparticle efficiently inhibits lung metastasis.
MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancer.
[Construction of stable focal adhesion kinase knockdown cell line and preliminary study of its properties].
Knockdown of chemokine receptor CXCR4 gene by RNA interference: Effects on the B16-F10 melanoma growth.
Persistent interferon transgene expression by RNA interference-mediated silencing of interferon receptors.
RNA interference of metastasis-associated gene 1 inhibits metastasis of B16F10 melanoma cells in a C57BL/6 mouse model.
Keratinocyte-derived laminin-332 protein promotes melanin synthesis via regulation of tyrosine uptake.